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Drug: Nicotine

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Total 8544 results found since Jan 2013.

Nicotine perturbs the microbiota of brown planthopper (Nilaparvata lugens st ål Hemiptera: Delphinidae)
Ecotoxicol Environ Saf. 2023 Aug 25;264:115383. doi: 10.1016/j.ecoenv.2023.115383. Online ahead of print.ABSTRACTBacterial symbionts exhibiting co-evolutionary patterns with insect hosts play a vital role in the nutrient synthesis, metabolism, development, reproduction, and immunity of insects. The brown planthopper (BPH) has a strong ability to adapt to various environmental stresses and can develop resistance to broad-spectrum insecticides. We aimed to investigate whether gut symbionts of BPH play a major role in the detoxification of insecticides and host fitness in unfavorable environments. Nicotine-treated rice plants...
Source: Ecotoxicology and Environmental Safety - August 27, 2023 Category: Environmental Health Authors: Gu Gong Yingying Hong Xuemei Wang Surajit De Mandal Junaid Zafar Ling Huang Fengliang Jin Xiaoxia Xu Source Type: research

Creating a sustainable rural general surgery workforce: what enables fellows to return as rural general surgeons?
CONCLUSION: Ensuring a sustainable general surgical workforce in a rural community requires employee and surgical leadership to ensure a collaborative and progressive culture, which offers work diversity, supports the family lifestyle and petitions for selecting those who embody the rural general surgeon identity. Post-fellowship positions can enable young general surgeons to have exposure to the realities of a rural lifestyle, which is likely to have a positive effect on recruitment. Due to the return investment of the fellowship program, we propose that the federal government should look at funding post-fellowship positi...
Source: Rural Remote Health - August 25, 2023 Category: Rural Health Authors: Jessica A Paynter Kirby R Qin Christine Cuthbertson Janelle Brennan Source Type: research

Partial desensitization of MYC2 transcription factor alters the interaction with jasmonate signaling components and affects specialized metabolism
Int J Biol Macromol. 2023 Aug 23:126472. doi: 10.1016/j.ijbiomac.2023.126472. Online ahead of print.ABSTRACTThe activity of bHLH transcription factor MYC2, a key regulator in jasmonate signaling and plant specialized metabolism, is sensitive to repression by JASMONATE-ZIM-domain (JAZ) proteins and co-activation by the mediator subunit MED25. The substitution of a conserved aspartic acid (D) to asparagine (N) in the JAZ-interacting domain (JID) of Arabidopsis MYC2 affects interaction with JAZ, although the mechanism remained unclear. The effects of the conserved residue MYC2D128 on interaction with MED25 have not been inves...
Source: International Journal of Biological Macromolecules - August 25, 2023 Category: Biochemistry Authors: Xin Hou Sanjay Kumar Singh Joshua R Werkman Yongliang Liu Qinghua Yuan Xia Wu Barunava Patra Xueyi Sui Ruiqing Lyu Bingwu Wang Xiaoyu Liu Yongqing Li Wei Ma Sitakanta Pattanaik Ling Yuan Source Type: research

Creating a sustainable rural general surgery workforce: what enables fellows to return as rural general surgeons?
CONCLUSION: Ensuring a sustainable general surgical workforce in a rural community requires employee and surgical leadership to ensure a collaborative and progressive culture, which offers work diversity, supports the family lifestyle and petitions for selecting those who embody the rural general surgeon identity. Post-fellowship positions can enable young general surgeons to have exposure to the realities of a rural lifestyle, which is likely to have a positive effect on recruitment. Due to the return investment of the fellowship program, we propose that the federal government should look at funding post-fellowship positi...
Source: Rural Remote Health - August 25, 2023 Category: Rural Health Authors: Jessica A Paynter Kirby R Qin Christine Cuthbertson Janelle Brennan Source Type: research

Partial desensitization of MYC2 transcription factor alters the interaction with jasmonate signaling components and affects specialized metabolism
Int J Biol Macromol. 2023 Aug 23:126472. doi: 10.1016/j.ijbiomac.2023.126472. Online ahead of print.ABSTRACTThe activity of bHLH transcription factor MYC2, a key regulator in jasmonate signaling and plant specialized metabolism, is sensitive to repression by JASMONATE-ZIM-domain (JAZ) proteins and co-activation by the mediator subunit MED25. The substitution of a conserved aspartic acid (D) to asparagine (N) in the JAZ-interacting domain (JID) of Arabidopsis MYC2 affects interaction with JAZ, although the mechanism remained unclear. The effects of the conserved residue MYC2D128 on interaction with MED25 have not been inves...
Source: International Journal of Biological Macromolecules - August 25, 2023 Category: Biochemistry Authors: Xin Hou Sanjay Kumar Singh Joshua R Werkman Yongliang Liu Qinghua Yuan Xia Wu Barunava Patra Xueyi Sui Ruiqing Lyu Bingwu Wang Xiaoyu Liu Yongqing Li Wei Ma Sitakanta Pattanaik Ling Yuan Source Type: research

One Man ’ s Quest to Heal the Oceans —And Maybe Save the World
Enric Sala—marine ecologist, conservationist, and ocean advocate—is standing under a life-size replica of a Northern Atlantic Right Whale at the natural history museum in Washington, D.C., and the air outside is smudged with wildfire smoke drifting down from Canada. It’s not surprising that Sala wants to talk about the smoke, or about whales. Their poop, however, is an unexpected twist. According to Sala, whale excrement, or, more precisely, the lack of it, has a role to play in the choking miasma that has forced my interview with one of the world’s foremost ocean explorers indoors instead of out on...
Source: TIME: Science - August 24, 2023 Category: Science Authors: Aryn Baker Tags: Uncategorized climate change healthscienceclimate TIME 2030 Source Type: news

Sexual dysfunction prevalence, risk factors, and help-seeking behavior in opioid agonist treatment and general psychiatry: a cross-sectional study
CONCLUSION: SD are common among psychiatric patients receiving OAT and general psychiatric patients seeking psychotherapy. Professionals providing mental healthcare to patients must emphasize prevention and routine assessments of sexual functioning needs.PMID:37608998 | PMC:PMC10440384 | DOI:10.3389/fpsyt.2023.1204236
Source: Pain Physician - August 23, 2023 Category: Anesthesiology Authors: Maximilian Meyer Jean N Westenberg Patrick Brunner Martin G ürtler Gerhard A Wiesbeck Undine E Lang Marc Vogel Kenneth M D ürsteler Source Type: research

Withdrawal from repeated nicotine vapor exposure increases somatic signs of physical dependence, anxiety-like behavior, and brain reward thresholds in adult male rats
In this study we assessed markers of withdrawal following 14 days of nicotine vapor exposure. For Experiment 1, 21 adult male rats were exposed to air or nicotine vapor for 14 consecutive days. Following exposure on day 14, rats were injected with the nicotinic receptor antagonist mecamylamine (3.0 mg/mL) and assessed for somatic withdrawal signs and anxiety-like behavior in the elevated plus maze. For Experiment 2, 12 adult male rats were tested for intracranial self-stimulation (ICSS) immediately following exposure to vehicle vapor (50%/50%, vegetable glycerin/propylene glycol) or nicotine vapor, for 14 consecutive days....
Source: Neuropharmacology - August 23, 2023 Category: Drugs & Pharmacology Authors: Michelle Mart ínez Veronika E Espinoza Valeria Garcia Kevin P Uribe Kenichiro Negishi Igor L Estevao Luis M Carcoba Laura E O'Dell Arshad M Khan Ian A Mendez Source Type: research

The influence of pain-related comorbidities on pain intensity and pain-related psychological distress in patients presenting with musculoskeletal pain
CONCLUSIONS: Depression was associated with greater pain intensity. No comorbidities were able to account for the extent of pain-related psychological distress.PMID:37611373 | DOI:10.1016/j.bjpt.2023.100532
Source: Health Physics - August 23, 2023 Category: Physics Authors: Steven L Spoonemore Ryan C McConnell William E Owen Jodi L Young Derek J Clewley Daniel I Rhon Source Type: research

Sexual dysfunction prevalence, risk factors, and help-seeking behavior in opioid agonist treatment and general psychiatry: a cross-sectional study
CONCLUSION: SD are common among psychiatric patients receiving OAT and general psychiatric patients seeking psychotherapy. Professionals providing mental healthcare to patients must emphasize prevention and routine assessments of sexual functioning needs.PMID:37608998 | PMC:PMC10440384 | DOI:10.3389/fpsyt.2023.1204236
Source: Pain Physician - August 23, 2023 Category: Anesthesiology Authors: Maximilian Meyer Jean N Westenberg Patrick Brunner Martin G ürtler Gerhard A Wiesbeck Undine E Lang Marc Vogel Kenneth M D ürsteler Source Type: research

E-Cigarette, or Vaping, Product Use-Associated Lung Injury (EVALI) Continues: An Opportunity for Pharmacist Intervention
Ann Pharmacother. 2023 Aug 21:10600280231193770. doi: 10.1177/10600280231193770. Online ahead of print.ABSTRACTElectronic cigarette (e-cigarette), or vaping, product use-associated lung injury (EVALI) was first identified and reported in 2019, but media coverage and reporting of cases drastically decreased when the COVID-19 pandemic started in early 2020. The syndrome has continued to occur since that time and it is critical that pharmacists are aware of how EVALI presents, and when it should be considered as a potential diagnosis. Inpatient and outpatient pharmacists play a vital role in the treatment of EVALI, and should...
Source: The Annals of Pharmacotherapy - August 22, 2023 Category: Drugs & Pharmacology Authors: Miranda R Andrus Source Type: research

Youth mental health and nicotine vape use: The moderating role of rural-urban/suburban school environments
CONCLUSIONS: Although differences in mental health were not shown based on rural versus urban/suburban school environments alone, findings showed that the relationship between nicotine vape use and mental health was stronger for youth attending high school in rural areas. Additional research is needed to understand the underlying social and environmental mechanisms that exacerbate this relationship. Future interventions might consider how to support and improve the mental health of rural nicotine vapers to better achieve health equity across different school environments.PMID:37607466 | DOI:10.1016/j.addbeh.2023.107830
Source: Addictive Behaviors - August 22, 2023 Category: Addiction Authors: Nan Wang Candice D Donaldson Source Type: research

E-Cigarette, or Vaping, Product Use-Associated Lung Injury (EVALI) Continues: An Opportunity for Pharmacist Intervention
Ann Pharmacother. 2023 Aug 21:10600280231193770. doi: 10.1177/10600280231193770. Online ahead of print.ABSTRACTElectronic cigarette (e-cigarette), or vaping, product use-associated lung injury (EVALI) was first identified and reported in 2019, but media coverage and reporting of cases drastically decreased when the COVID-19 pandemic started in early 2020. The syndrome has continued to occur since that time and it is critical that pharmacists are aware of how EVALI presents, and when it should be considered as a potential diagnosis. Inpatient and outpatient pharmacists play a vital role in the treatment of EVALI, and should...
Source: The Annals of Pharmacotherapy - August 22, 2023 Category: Drugs & Pharmacology Authors: Miranda R Andrus Source Type: research