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Cancer: Gastric (Stomach) Cancer
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Clinical significance of expression level of ZNF471 in gastric cancer
CONCLUSION: ZNF471 functions as a tumor suppressor during the pathogenesis of GC. Thus, it is a promising biomarker for diagnosis and therapy of GC.PMID:37693683 | PMC:PMC10492033
Source: International Journal of Clinical and Experimental Pathology - September 11, 2023 Category: Pathology Authors: Siyuan Li Diyang Chen Huamin Zhang Yong Yang Jianguo Huai Linna Huang Kai Fan Tongyuan Lin Baijing Ding Source Type: research
Study of LncRNA BANCR Expression in Tumor Tissues and Adjacent Normal Tissues in Gastric Cancer Patients
CONCLUSIONS: The observed upregulation of BANCR in GC tissues implies its potential involvement as an oncogenic lncRNA in GC patients. Furthermore, BANCR may serve as a promising biomarker for identification and treatment of GC.PMID:37694252 | PMC:PMC10492603 | DOI:10.4103/abr.abr_260_22
Source: Adv Data - September 11, 2023 Category: Epidemiology Authors: Raha Nikanfar Rozhin Dabbaghi Ali Rajabi Shahriar Hashemzadeh Behzad Baradaran Shahram Teimourian Reza Safaralizadeh Source Type: research
Clinical significance of expression level of ZNF471 in gastric cancer
CONCLUSION: ZNF471 functions as a tumor suppressor during the pathogenesis of GC. Thus, it is a promising biomarker for diagnosis and therapy of GC.PMID:37693683 | PMC:PMC10492033
Source: International Journal of Clinical and Experimental Pathology - September 11, 2023 Category: Pathology Authors: Siyuan Li Diyang Chen Huamin Zhang Yong Yang Jianguo Huai Linna Huang Kai Fan Tongyuan Lin Baijing Ding Source Type: research
Study of LncRNA BANCR Expression in Tumor Tissues and Adjacent Normal Tissues in Gastric Cancer Patients
CONCLUSIONS: The observed upregulation of BANCR in GC tissues implies its potential involvement as an oncogenic lncRNA in GC patients. Furthermore, BANCR may serve as a promising biomarker for identification and treatment of GC.PMID:37694252 | PMC:PMC10492603 | DOI:10.4103/abr.abr_260_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Raha Nikanfar Rozhin Dabbaghi Ali Rajabi Shahriar Hashemzadeh Behzad Baradaran Shahram Teimourian Reza Safaralizadeh Source Type: research
Synthesis and In Silico Studies of Quinazolinones as PARP-1 Inhibitors
CONCLUSION: All the synthesized compounds have a better docking score than niraparib (-9.05). Further, the synthesized compounds have a favorable ADME profile. Therefore, they may serve as important leads in discovering PARP-1 inhibitors.PMID:37691193 | DOI:10.2174/1386207326666230905153443
Source: Combinatorial Chemistry and High Throughput Screening - September 11, 2023 Category: Chemistry Authors: Maneesh Guleria Adarsh Kumar Ankit Kumar Singh Pradeep Kumar Source Type: research
Clinical significance of expression level of ZNF471 in gastric cancer
CONCLUSION: ZNF471 functions as a tumor suppressor during the pathogenesis of GC. Thus, it is a promising biomarker for diagnosis and therapy of GC.PMID:37693683 | PMC:PMC10492033
Source: International Journal of Clinical and Experimental Pathology - September 11, 2023 Category: Pathology Authors: Siyuan Li Diyang Chen Huamin Zhang Yong Yang Jianguo Huai Linna Huang Kai Fan Tongyuan Lin Baijing Ding Source Type: research
Evolving perspectives regarding the role of the PD-1/PD-L1 pathway in gastric cancer immunotherapy
Biochim Biophys Acta Mol Basis Dis. 2023 Sep 9:166881. doi: 10.1016/j.bbadis.2023.166881. Online ahead of print.ABSTRACTGastric cancer (GC) is an increasing global health problem and is one of the leading cancers worldwide. Traditional therapies, such as radiation and chemotherapy, have made limited progress in enhancing their efficacy for advanced GC. The development of immunotherapy for advanced GC has considerably improved with a deeper understanding of the tumor microenvironment. Immunotherapy using checkpoint inhibitors is a new therapeutic option that has made substantial advances in the treatment of other malignanci...
Source: Biochimica et Biophysica Acta - September 11, 2023 Category: Biochemistry Authors: Xianzhe Yu Xiaoqian Zhai Juan Wu Qingbo Feng Chenggong Hu Lingling Zhu Qinghua Zhou Source Type: research
Study of LncRNA BANCR Expression in Tumor Tissues and Adjacent Normal Tissues in Gastric Cancer Patients
CONCLUSIONS: The observed upregulation of BANCR in GC tissues implies its potential involvement as an oncogenic lncRNA in GC patients. Furthermore, BANCR may serve as a promising biomarker for identification and treatment of GC.PMID:37694252 | PMC:PMC10492603 | DOI:10.4103/abr.abr_260_22
Source: Adv Data - September 11, 2023 Category: Epidemiology Authors: Raha Nikanfar Rozhin Dabbaghi Ali Rajabi Shahriar Hashemzadeh Behzad Baradaran Shahram Teimourian Reza Safaralizadeh Source Type: research
Clinical significance of expression level of ZNF471 in gastric cancer
CONCLUSION: ZNF471 functions as a tumor suppressor during the pathogenesis of GC. Thus, it is a promising biomarker for diagnosis and therapy of GC.PMID:37693683 | PMC:PMC10492033
Source: International Journal of Clinical and Experimental Pathology - September 11, 2023 Category: Pathology Authors: Siyuan Li Diyang Chen Huamin Zhang Yong Yang Jianguo Huai Linna Huang Kai Fan Tongyuan Lin Baijing Ding Source Type: research
The disappearance of gastric metastasis and liver metastasis in non-small cell lung adenocarcinoma is due to osimertinib
CONCLUSIONS: This is the first report to our knowledge of a patient who presented with gastric and hepatic metastases from lung cancer and achieved complete remission with osimertinib and local radiotherapy, with good quality of life, which also provides a basis for future clinical work and is of great significance.PMID:37695388 | DOI:10.1007/s00432-023-05386-7
Source: Clinical Lung Cancer - September 11, 2023 Category: Cancer & Oncology Authors: Yun Wang Chao Yan Chuantao Zhang Enhao Yu Kai Wang Xiangyong Liu Jie Yu Chunyang Zhou Aijie Yang Source Type: research
Mangostin enhances efficacy of aminolevulinic acid-photodynamic therapy against cancer through inhibition of ABCG2 activity
CONCLUSION: These findings suggest that mangostin enhances the efficacy of ALA-PDT in cancer through inhibition of ABCG2 activity.PMID:37696317 | DOI:10.1016/j.pdpdt.2023.103798
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Hung Wei Lai Yukitaka Tani Udomlak Sukatta Prapassorn Rugthaworn Asada Thepyos Shinkuro Yamamoto Hideo Fukuhara Keiji Inoue Hideya Yuasa Hiroyuki Nakamura Shun-Ichiro Ogura Source Type: research
The disappearance of gastric metastasis and liver metastasis in non-small cell lung adenocarcinoma is due to osimertinib
CONCLUSIONS: This is the first report to our knowledge of a patient who presented with gastric and hepatic metastases from lung cancer and achieved complete remission with osimertinib and local radiotherapy, with good quality of life, which also provides a basis for future clinical work and is of great significance.PMID:37695388 | DOI:10.1007/s00432-023-05386-7
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Yun Wang Chao Yan Chuantao Zhang Enhao Yu Kai Wang Xiangyong Liu Jie Yu Chunyang Zhou Aijie Yang Source Type: research
