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Total 15 results found since Jan 2013.

Parkinson ’ s Patients Get More Mobility And Better Balance With Whole Body Vibration Therapy
I’ve always believed that with a little coaxing, your body can self-heal – and the same is true for your brain. Conventional doctors will never tell you this. For them, being a physician means managing symptoms with Big Pharma meds. But for years, I’ve been helping patients recover using dietary changes, lasers, stem cells, and hyperbaric oxygen (HBOT). These therapies help your body heal itself. No Big Pharma drug can do this. But I recently began researching another natural therapy – called Whole Body Vibration, or WBV – that can help Parkinson’s patients regain their mobility and balance. WBV isn’t new. It...
Source: Al Sears, MD Natural Remedies - August 28, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Health Natural Cures Source Type: news

Efficacy and safety of human-derived neural stem cell in patients with ischaemic stroke: study protocol for a randomised controlled trial
Introduction Stroke is the most common cause of neurological disability in adults worldwide. Neural stem cell (NSC) transplantation has shown promising results as a treatment for stroke in animal experiments. The pilot investigation of stem cells in stroke phase 1 and phase 2 trials showed that transplantation of the highest dose (20 million cells) was well tolerated. Preliminary clinical benefits have also been observed. However, the trials were open-label and had a small sample size. Furthermore, human NSCs (hNSCs) were intracerebrally implanted, and some serious adverse events were considered to be related to the surgic...
Source: BMJ Open - November 8, 2022 Category: General Medicine Authors: Xie, C., Wang, K., Peng, J., Jiang, X., Pan, S., Wang, L., Wu, Y., Guan, Y. Tags: Open access, Neurology Source Type: research

Clinical application of stem cell therapy in neurogenic bladder: a systematic review and meta-analysis
ConclusionAlthough most clinical trials provide evidence of the safety and effectiveness of MSCs on the management of NGB, the meta-analysis results did not show a significant improvement; however, the interpretation of study results is difficult because of the lack of placebo controls.
Source: International Urogynecology Journal - November 12, 2021 Category: OBGYN Source Type: research

Allogeneic adipose tissue-derived mesenchymal stem cells in ischaemic stroke (AMASCIS-02): a phase IIb, multicentre, double-blind, placebo-controlled clinical trial protocol
Introduction Stroke is a serious public health problem, given it is a major cause of disability worldwide despite the spread of recanalisation therapies. Enhancement of brain plasticity with stem cell administration is a promising innovative therapy to reduce sequelae in these patients. Methods and analysis We have developed a phase IIb, multicentre, randomised, double-blind, placebo-controlled clinical trial protocol to evaluate the safety and efficacy of intravenous administration of allogeneic adipose tissue-derived mesenchymal stem cells (AD-MSCs) in patients with acute ischaemic stroke, concurrently with conventional...
Source: BMJ Open - August 9, 2021 Category: General Medicine Authors: de Celis-Ruiz, E., Fuentes, B., Moniche, F., Montaner, J., Borobia, A. M., Gutierrez-Fernandez, M., Diez-Tejedor, E. Tags: Open access, Neurology Source Type: research

Stem cell transplantation for ischemic stroke.
CONCLUSIONS: Overall, in participants with ischemic stroke, stem cell transplantation was associated with a reduced neurological impairment, but not with a better functional outcome. No obvious safety concerns were raised. However, these conclusions came mostly from small RCTs with high risk of bias, and the certainty of the evidence ranged from low to very low. More well-designed trials are needed. PMID: 31055832 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - May 4, 2019 Category: General Medicine Authors: Boncoraglio GB, Ranieri M, Bersano A, Parati EA, Del Giovane C Tags: Cochrane Database Syst Rev Source Type: research

Challenge to the Intestinal Mucosa During Sepsis
Conclusion The impact of sepsis on the gut is manifold, e.g., sepsis mediated alteration of the gut-blood barrier and increase in the intestinal permeability, which may correlate with the phenomena of bacterial translocation and lymphatic activation (“toxic-lymph”). Systemic consequences of sepsis are widespread and concern to the coagulative system, the microbiome as well as enzymes, such as pancreatic proteases, MMPs and IAPs. Nevertheless, the therapeutic approaches for modulating the mucosal immune system are still rarely effective in daily routine. Recent published studies showing that treatment with ...
Source: Frontiers in Immunology - April 29, 2019 Category: Allergy & Immunology Source Type: research

Osteoporosis and Sarcopenia Increase Frailty Syndrome in the Elderly
Conclusions World population is aging and the increase in life expectancy is often unhealthy. In particular, musculoskeletal aging, which leads to sarcopenia and osteoporosis, has several causes such as changes in body composition, inflammation, and hormonal imbalance. Sarcopenia, osteoporosis, and more frequently, sarcopenic obesity are commonly associated with aging and frequently closely linked each other, often leading to the development of a frailty syndrome. Frailty syndrome favors an increased risk of loss function in daily activities, for cardiovascular diseases, cancers, falls, and mortality. As the number of eld...
Source: Frontiers in Endocrinology - April 23, 2019 Category: Endocrinology Source Type: research

Association between Exposure to p,p ′-DDT and Its Metabolite p,p′-DDE with Obesity: Integrated Systematic Review and Meta-Analysis
Conclusions: We classified p,p′-DDT and p,p′-DDE as “presumed” to be obesogenic for humans, based on a moderate level of primary human evidence, a moderate level of primary in vivo evidence, and a moderate level of supporting evidence from in vivo and in vitro studies. https://doi.org/10.1289/EHP527 Received: 17 May 2016 Revised: 04 May 2017 Accepted: 09 May 2017 Published: 18 September 2017 Please address correspondence to M.A. La Merrill, Dept. of Environmental Toxicology, University of California, Davis, 1 Shields Ave., 4245 Meyer Hall, Davis, CA 95616-5270 USA. Telephone: (530) 754-7254. Email: mlamerrill...
Source: EHP Research - September 18, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research

SanBio touts 1-year data on stem cell transplant for stroke
SanBio Inc. (TYO:4592) released 1-year interim data from the phase 1/2a, open-label, single-arm dose escalation study of its intracerebral stem cell implant designed for stroke patients. The Mountain View, Calif.-based company touted the results, which indicated that itsSB623 stem cell treatment was generally safe, well-tolerated and associated with improved motor functions in patients  suffering with chronic impairment following an ischemic stroke. SanBio presented interim results from the study at the American Congress of Rehabilitation Medicine Conference last week, and claims that the study is the 1st of its kind...
Source: Mass Device - November 4, 2016 Category: Medical Equipment Authors: Sarah Faulkner Tags: Drug-Device Combinations Neurological Research & Development Stem Cells SanBio Inc Source Type: news

Disrupting Today's Healthcare System
This week in San Diego, Singularity University is holding its Exponential Medicine Conference, a look at how technologists are redesigning and rebuilding today's broken healthcare system. Healthcare today is reactive, retrospective, bureaucratic and expensive. It's sick care, not healthcare. This blog is about why the $3 trillion healthcare system is broken and how we are going to fix it. First, the Bad News: Doctors spend $210 billion per year on procedures that aren’t based on patient need, but fear of liability. Americans spend, on average, $8,915 per person on healthcare – more than any other count...
Source: Healthy Living - The Huffington Post - November 9, 2015 Category: Consumer Health News Source Type: news

Nature’s Most Powerful Age Fighter?
When I lecture at anti-aging conferences around the world, I get a good sense of what the leading anti-aging physicians are thinking about. And I’m surprised by how many are still holding out hope for an anti-aging “drug.” But I’m not holding my breath. And even if the FDA approved a drug for aging, it would likely include a laundry list of side effects, and only affect a small range of age-related decline. I’ve always had more faith in nature. Many of the most powerful age fighters are naturally occurring, and they do a better job of supporting and lengthening your telomeres than any drug. Te...
Source: Al Sears, MD Natural Remedies - July 6, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging Nutrition omega 3 telomere vitamin C Source Type: news

Science Scandal Triggers Suicide, Soul-Searching in Japan
It was a success story that Japan sorely needed: a young, talented and beautiful researcher developed a cheap and simple way to grow versatile stem cells. MoreTokyo: What to See and What to SkipThis Is How TIME Explained the Atomic Bomb in 1945Iselle Weakens to Tropical Storm as Julio Barrels On NBC NewsIsrael Vows to 'Forcefully React' as Cease-Fire Ends NBC NewsCops Tampered With Pistorius Evidence, Lawyer Alleges NBC NewsThe discovery promised to usher in a new age of regenerative medicine, validated Japan as a leader in scientific research and demonstrated that even in a male-dominated society, women could excel when g...
Source: TIME.com: Top Science and Health Stories - August 8, 2014 Category: Consumer Health News Authors: Charlie Campbell Tags: Uncategorized haruko obokata Japan Research Science Stem Cells Suicide Yoshiki Sasai Source Type: news

Final agenda available for CRF sponsored conference on stem cell therapy for heart disease
(Cardiovascular Research Foundation) The Eighth International Conference on Cell Therapy for Cardiovascular Disease, sponsored by the Cardiovascular Research Foundation, will be held Jan. 23-25, 2013. The conference is the premier meeting dedicated to the evolving field of cell-based therapies for the repair and regeneration of cardiac and vascular disease, as well as related diseases such as diabetes and stroke.
Source: EurekAlert! - Medicine and Health - January 17, 2013 Category: Global & Universal Source Type: news

Agenda set for upcoming CRF-sponsored conference on stem cell therapy for heart disease
(Cardiovascular Research Foundation) The 8th International Conference on Cell Therapy for Cardiovascular Disease, sponsored by the Cardiovascular Research Foundation will be held Jan. 23-25, 2013. The conference is a comprehensive program dedicated to the evolving field of cell-based therapies for the repair and regeneration of cardiac and vascular disease, as well as related diseases such as diabetes and stroke.
Source: EurekAlert! - Medicine and Health - January 3, 2013 Category: Global & Universal Source Type: news