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Therapy: Cardiac Resynchronization Therapy

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Total 150 results found since Jan 2013.

Medtronic touts reduced AF, improved activity in AdaptivCRT studies
Medtronic (NYSE:MDT) today released results from two real-world analyses of its AdaptivCRT algorithm, touting that its use was linked to a reduction in atrial fibrillation episodes and higher patient activity levels. Results from the analyses, which involved a total of 408 patients at 26 centers in Italy, were presented at the European Heart Rhythm Association’s Scientific Sessions 2018 in Barcelona, Spain, the company said. Medtronic’s AdaptivCRT algorithm is designed to adjust pacing to the heart dependent upon evaluations of heart rhythm made every minute, the company said. The program has been shown to in...
Source: Mass Device - March 20, 2018 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Assist Devices Cardiac Implants Cardiovascular Clinical Trials Software / IT Medtronic Source Type: news

Can We Use the Intrinsic Left Ventricular Delay (QLV) to Optimize the Pacing Configuration for Cardiac Resynchronization Therapy With a Quadripolar Left Ventricular Lead? Original Articles
Conclusions: The large variation in acute hemodynamic response indicates that the choice of the stimulated electrode on a quadripolar lead is important. Although QLV/QRSd was associated with acute hemodynamic response at group level, it cannot be used to select the optimal electrode in the individual patient.
Source: Circulation: Arrhythmia and Electrophysiology - March 16, 2018 Category: Cardiology Authors: van Everdingen, W. M., Zweerink, A., Cramer, M. J., Doevendans, P. A., Nguyen, U. C., van Rossum, A. C., Prinzen, F. W., Vernooy, K., Allaart, C. P., Meine, M. Tags: Heart Failure, Pacemaker Original Articles Source Type: research

EBR Systems launches trial for wireless pacer
EBR Systems said yesterday that it launched a 350-patient investigational device exemption trial of its Wise wireless pacemaker it hopes to use to win FDA approval. Sunnyvale, Calif.-based EBR’s device uses a subcutaneous generator to wirelessly deliver ultrasound energy to a “pellet” implanted in the right ventricle, which it uses to synchronize the left and right ventricles. The system is designed to eliminate the need for a left ventricular lead by allowing the operating physician to place the stimulation “pellet” in a patient-specific location inside the left ventricle. The FDA approved the Solve-CRT stu...
Source: Mass Device - March 8, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Cardiovascular Clinical Trials Cardiac Rhythm Management EBR Systems Inc. Source Type: news

Recent advances in heart failure
Purpose of review Acute heart failure continues to be a challenge as there is limited benefit of numerous agents that have been tested. Cardiac resynchronization therapy remains standard of care, yet timing and need for implantable cardiac defibrillator has been brought into question with the recent randomized trials. Several recent advances have been made towards management of heart failure both in drug and device therapy. The purpose of this review is to provide an update on the most important recent studies on heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpE...
Source: Current Opinion in Cardiology - February 8, 2018 Category: Cardiology Tags: Special Commentaries Source Type: research

Long-term outcome of catheter ablation and other form of therapy for electrical storm in patients with implantable cardioverter-defibrillators
ConclusionsIn patients treated with RFCA for ES, all-cause mortality was significantly lower compared to the group treated with other methods.
Source: Journal of Interventional Cardiac Electrophysiology - October 24, 2017 Category: Cardiology Source Type: research

Heart failure study of multipoint pacing effects on ventriculoarterial coupling: Rationale and design of the HUMVEE trial
Cardiac resynchronization therapy (CRT) is an established therapy for symptomatic heart failure (HF). Unfortunately, many recipients remain nonresponders. Studies have revealed the potential role of multipoint pacing (MPP) in improving response and outcomes. The aim of this study is to compare the effects of MPP against those of standard biventricular pacing (BVP) on (i) ventriculoarterial coupling (VAC) and energy efficiency of the failing heart, (ii) diastolic function, (iii) quality of life, and (iv) NT‐proBNP levels and glomerular filtration rate (GFR) during a follow‐up of 13 months. HUMVEE is a single‐center, ...
Source: Annals of Noninvasive Electrocardiology - October 15, 2017 Category: Cardiology Authors: Christina Chrysohoou, Polychronis Dilaveris, Christos ‐Konstantinos Antoniou, Ioannis Skiadas, Konstantinos Konstantinou, Konstantinos Gatzoulis, Ioannis Kallikazaros, Dimitrios Tousoulis Tags: ORIGINAL ARTICLE Source Type: research

Frailty syndrome: an emerging clinical problem in the everyday management of clinical arrhythmias. The results of the European Heart Rhythm Association survey
In conclusion, the complex clinical condition in frail patients presenting with arrhythmias warrants an integrated multidisciplinary approach both for the management of rhythm disturbances and for the decision on using CIEDs.
Source: Europace - October 10, 2017 Category: Cardiology Source Type: research

ESC 2017 Roundup: Biotronik touts lowered mortality for AF patients treated with cath ablation
Biotronik today released results from the Castle-AF study exploring the use of catheter ablation to treat heart failure patients with atrial fibrillation, touting a 38% composite reduction in all-cause mortality and hospitalization for worsening heart failure. The 398-patient, 33-site study compared the results of catheter ablation treatment for AF in heart failure patients using implantable cardioverter defibrillators or cardiac resynchronization therapy defibrillators to standard-of-care pharmacological therapy, the company said. Biotronik touted it as the largest study of its kind to date. Results indicated a 47% reduc...
Source: Mass Device - August 28, 2017 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Assist Devices Cardiac Implants Cardiovascular Clinical Trials Biotronik Medtronic Source Type: news

Clinical implications of long term ECG monitoring: from loop recorder to devices remote control.
Authors: DI Cori A, DE Lucia R Abstract Long term ECG monitoring has become nowadays an indispensable technology for prevention, management and treatment of many cardiac issues. Today long term ECG monitoring is achievable through loop recorders (LR) and cardiac devices (CIED) like pacemaker (PM), implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy device-defibrillators (CRT- Ds), all of which associated with remote monitoring (RM). Targeted long term ECG monitoring Patients who have recurrent non documented episodes of palpitations, unexplained episodes of syncope, cryptogenic stro...
Source: Minerva Cardioangiologica - July 20, 2017 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Heart rate and dyssynchrony in patients with cardiac resynchronization therapy: a pilot study.
The objective of this pilot study was to describe the impact of paced heart rate on left ventricular (LV) mechanical dyssynchrony in synchronous compared to dyssynchronous pacing modes in patients with heart failure. METHODS: Echocardiography was performed in 14 cardiac resynchronization therapy (CRT) patients at paced heart rates of 70 and 90 bpm in synchronous- (CRT), and dyssynchronous (atrial pacing + wide QRS activation) pacing modes. LV dyssynchrony was quantified using the 12-segment standard deviation model (Ts-SD) derived from Tissue Doppler Imaging. In addition, cardiac cycle intervals were assessed using...
Source: Scandinavian Cardiovascular Journal - March 27, 2017 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

MassDevice.com +5 | The top 5 medtech stories for March 17, 2017
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. GlucoMe tackles connected diabetes management with acoustic data transmission The Centers for Disease Control & Prevention predict that by 2050, if current trends continue, 1 in 3 adults in the U.S. will have diabetes. The d...
Source: Mass Device - March 17, 2017 Category: Medical Equipment Authors: Brad Perriello Tags: News Well Plus 5 Source Type: news

Atrioventricular dyssynchrony from empiric device settings is common in cardiac resynchronization therapy and adversely impacts left ventricular morphology and function
ConclusionOur study suggests that up to 50% of patients with empiric device settings have AV dyssynchrony at 6 months despite atrioventricular delay optimization (AVO) algorithms. As AV dyssynchrony is common and has proven to be modifiable, a strategic approach to Doppler echocardiography‐guided AVO after CRT is warranted, particularly in nonresponders where the LV filling pattern is fused or truncated.
Source: Echocardiography - February 28, 2017 Category: Cardiology Authors: Gregory J. Sinner, Vedant A. Gupta, Arash Seratnahaei, Richard J. Charnigo, Yousef H. Darrat, Samy C. Elayi, Steve W. Leung, Vincent L. Sorrell Tags: ORIGINAL INVESTIGATION Source Type: research

Atrial Fibrillation and Ventricular Arrhythmias: Sex Differences in Electrophysiology, Epidemiology, Clinical Presentation, and Clinical Outcomes.
Abstract Sex-specific differences in the epidemiology, pathophysiology, clinical presentation, clinical treatment, and clinical outcomes of atrial fibrillation (AF), sustained ventricular arrhythmias, and sudden cardiac death are recognized. Sex hormones cause differences in cardiac electrophysiological parameters between men and women that may affect the risk for arrhythmias. The incidence and prevalence of AF is lower in women than in men. However, because women live longer and AF prevalence increases with age, the absolute number of women with AF exceeds that of men. Women with AF are more symptomatic, present ...
Source: Circulation - February 6, 2017 Category: Cardiology Authors: Gillis AM Tags: Circulation Source Type: research

Gauging the response to cardiac resynchronization therapy: The important interplay between predictor variables and definition of a favorable outcome
ConclusionThe definition of a favorable CRT response influenced the optimal predictor variable(s). Standardization of defining a favorable response to CRT is needed to guide clinical decision making processes.
Source: Echocardiography - January 10, 2017 Category: Cardiology Authors: Milan Petrovic, Marija Petrovic, Goran Milasinovic, Bosiljka Vujisic Tesic, Danijela Trifunovic, Olga Petrovic, Ivana Nedeljkovic, Ivana Petrovic, Marko Banovic, Marija Boricic ‐Kostic, Jelena Petrovic, Ross Arena, Dejana Popovic Tags: ORIGINAL INVESTIGATION Source Type: research

Endocardial left ventricular pacing for cardiac resynchronization: systematic review and meta-analysis
ConclusionLV endocardial pacing appears to be a viable technique when conventional lead placement is not possible. Response rates were heterogeneous but comparable with conventional CRT. There is likely to be a small increase over expected rates of stroke, although included patients were high risk.
Source: Europace - January 10, 2017 Category: Cardiology Source Type: research