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Therapy: Cardiac Resynchronization Therapy

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Total 150 results found since Jan 2013.

Efficient preloading of the ventricles by a properly timed atrial contraction underlies stroke work improvement in the acute response to cardiac resynchronization therapy
Conclusion: Efficient preloading of the ventricles by a properly timed atrial contraction is responsible for a significant stroke work improvement in the acute CRT response.
Source: Heart Rhythm - August 7, 2013 Category: Cardiology Authors: Yuxuan Hu, Viatcheslav Gurev, Jason Constantino, Natalia Trayanova Tags: Experimental Source Type: research

Noninvasive Monitoring of Stroke Volume With Resynchronization Devices in Patients With Ischemic Cardiomyopathy
Conclusions: In CRT patients with chronic infarction and wall motion abnormalities, impedance is a valid parameter to estimate stroke volume and to guide optimization of CRT timing.
Source: Journal of Cardiac Failure - August 1, 2013 Category: Cardiology Authors: Michael Kühne, Mario Bocchiardo, Herbert Nägele, Beat Schaer, Michael Lippert, Christian Sticherling, Stefan Osswald Tags: Clinical Investigations Source Type: research

Effects of remote monitoring of cardiac implantable electronic devices after stroke or transient ischemic attack
Conclusion We found that remote monitoring as compared with conventional in-hospital visits may contribute to a better outcome in CIED recipients who had suffered from an ischemic cerebral event.
Source: Journal of Cardiovascular Medicine - August 1, 2019 Category: Cardiology Tags: Research articles: Telemonitoring Source Type: research

PM101 Impact of Right Ventricular Stroke Work Index on the Echocardiographic and Clinical Response to Cardiac Resynchronization Therapy
Right ventricular (RV) dysfunction is considered a major determinant of outcome in patients with moderate-to-severe heart failure (HF). Baseline RV function may play a role in determining the left ventricular response to CRT. The RV stroke work index (RVSWI) calculates RV workload and contractility based on invasive hemodynamics. However there is no data about the value of basal RVSWI in predicting the left ventricular response to CRT.
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: N. Arat, E. Ozenc, O. Yildiz, S. Usalp, O. Demiroz, C. Ciftci Tags: Poster Abstract Source Type: research

Effects of Cardiac Resynchronization Therapy on Cardiac Remodeling and Contractile Function: Results From Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction (REVERSE) Heart Failure
Conclusion In patients with NYHA Class I/II heart failure, cardiac resynchronization therapy exerts favorable changes in left ventricular end-systolic and end-diastolic volumes and the volume intercept. The volume intercept may be useful to gain insight into prognosis in heart failure. Clinical Trial Registration URL: https://www.clinicaltrials.gov/. Unique identifier: NCT00271154.
Source: JAHA:Journal of the American Heart Association - September 11, 2015 Category: Cardiology Authors: St. John Sutton, M., Cerkvenik, J., Borlaug, B. A., Daubert, C., Gold, M. R., Ghio, S., Chirinos, J. A., Linde, C., Ky, B. Tags: Heart Failure Source Type: research

The influence of right ventricular stimulation on acute response to cardiac resynchronisation therapy.
CONCLUSION: The haemodynamic effect of addition of RVapex stimulation to LV stimulation differs widely among patients receiving CRT. Poor RV function is associated with poor response to LV but not BiV stimulation. PMID: 26649436 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - December 9, 2015 Category: Cardiology Authors: Wu L, de Roest GJ, Hendriks ML, van Rossum AC, de Cock CC, Allaart CP Tags: Neth Heart J Source Type: research

Larger Interventricular Conduction Time Enhances Mechanical Response to Resynchronization Therapy
ConclusionsAn optimal acute response to CRT can be obtained by positioning the LV lead at the site associated with the maximum RV‐to‐LV conduction time. A significant correlation appears to exist between RV‐to‐LV conduction time and the improvement in systolic function with CRT.
Source: Pacing and Clinical Electrophysiology : PACE - January 10, 2013 Category: Cardiology Authors: LUIGI PADELETTI, PAOLO PIERAGNOLI, GIUSEPPE RICCIARDI, LAURA PERROTTA, ALESSANDRO P. PERINI, GINO GRIFONI, ILARIA RICCERI, MARGHERITA PADELETTI, VINCENZO LIONETTI, SERGIO VALSECCHI Tags: Original Article Source Type: research

Mechano-electrical coupling as framework for understanding functional remodeling during LBBB and CRT.
In conclusion, MEC may represent a useful framework for better understanding the long-term changes in cardiac electrophysiology and contraction following LBBB as well as CRT. PMID: 24748591 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - April 18, 2014 Category: Physiology Authors: Kuijpers NH, Hermeling E, Lumens J, Eikelder HT, Delhaas T, Prinzen FW Tags: Am J Physiol Heart Circ Physiol Source Type: research

Mechano-electrical coupling as framework for understanding functional remodeling during LBBB and CRT
In conclusion, MEC may represent a useful framework for better understanding the long-term changes in cardiac electrophysiology and contraction following LBBB as well as CRT.
Source: AJP: Heart and Circulatory Physiology - June 15, 2014 Category: Cardiology Authors: Kuijpers, N. H. L., Hermeling, E., Lumens, J., ten Eikelder, H. M. M., Delhaas, T., Prinzen, F. W. Tags: CARDIAC EXCITATION AND CONTRACTION Source Type: research

Simultaneous His Bundle and Left Ventricular Pacing for Optimal Cardiac Resynchronization Therapy Delivery: Acute Hemodynamic Assessment by Pressure-Volume Loops Original Articles
Conclusions— Standard right ventricular apex+LV and LV-only pacing enhanced systolic function and LV synchrony at individually optimized AVD close to the measured intrinsic P-H interval. By contrast, HIS+LV pacing yielded improvements, regardless of AVD setting. These findings support the hypothesis of the crucial role of intrinsic right ventricular conduction in optimal cardiac resynchronization therapy delivery.
Source: Circulation: Arrhythmia and Electrophysiology - May 8, 2016 Category: Cardiology Authors: Padeletti, L., Pieragnoli, P., Ricciardi, G., Innocenti, L., Checchi, L., Padeletti, M., Michelucci, A., Picariello, F., Valsecchi, S. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Congenital Heart Disease, Heart Failure, Pacemaker Original Articles Source Type: research

Atrial Fibrillation and Ventricular Arrhythmias: Sex Differences in Electrophysiology, Epidemiology, Clinical Presentation, and Clinical Outcomes.
Abstract Sex-specific differences in the epidemiology, pathophysiology, clinical presentation, clinical treatment, and clinical outcomes of atrial fibrillation (AF), sustained ventricular arrhythmias, and sudden cardiac death are recognized. Sex hormones cause differences in cardiac electrophysiological parameters between men and women that may affect the risk for arrhythmias. The incidence and prevalence of AF is lower in women than in men. However, because women live longer and AF prevalence increases with age, the absolute number of women with AF exceeds that of men. Women with AF are more symptomatic, present ...
Source: Circulation - February 6, 2017 Category: Cardiology Authors: Gillis AM Tags: Circulation Source Type: research

ESC 2017 Roundup: Biotronik touts lowered mortality for AF patients treated with cath ablation
Biotronik today released results from the Castle-AF study exploring the use of catheter ablation to treat heart failure patients with atrial fibrillation, touting a 38% composite reduction in all-cause mortality and hospitalization for worsening heart failure. The 398-patient, 33-site study compared the results of catheter ablation treatment for AF in heart failure patients using implantable cardioverter defibrillators or cardiac resynchronization therapy defibrillators to standard-of-care pharmacological therapy, the company said. Biotronik touted it as the largest study of its kind to date. Results indicated a 47% reduc...
Source: Mass Device - August 28, 2017 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Assist Devices Cardiac Implants Cardiovascular Clinical Trials Biotronik Medtronic Source Type: news

Device-Detected Atrial Fibrillation: Evidencing the Knowledge Gap.
Abstract Stroke is a devastating complication of atrial fibrillation (AF) the odds of which can be reduced by use of oral anticoagulation based on the stroke risk score.1,2 Patients with asymptomatic clinical AF have a similar stroke risk as patients with symptomatic clinical AF.3 Thus far, electrocardiographic- (ECG) or Holter monitor-detected AF is a prerequisite before use of oral anticoagulation,1,2 because the guideline recommendations are based on studies that included only ECG- or Holter-detected AF ('clinical' AF).1,2 In the past decades increasing number of cardiac implantable electronic devices (CIED) ha...
Source: Circulation - March 16, 2019 Category: Cardiology Authors: Mulder BA, van Gelder IC, Rienstra M Tags: Circulation Source Type: research