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Therapy: Cardiac Resynchronization Therapy

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Total 150 results found since Jan 2013.

Effects of AV-delay optimization on hemodynamic parameters in patients with VDD pacemakers.
CONCLUSION: AV-delay optimization in patients treated with VDD-PMs exhibits immediate beneficial effects on hemodynamic parameters that are sustained for 3 months. PMID: 24652015 [PubMed - as supplied by publisher]
Source: Wiener Klinische Wochenschrift - March 21, 2014 Category: Journals (General) Authors: Krychtiuk KA, Nürnberg M, Volker R, Pachinger L, Jarai R, Freynhofer MK, Wojta J, Huber K, Weiss TW Tags: Wien Klin Wochenschr Source Type: research

Scar tissue–guided left ventricular lead placement for cardiac resynchronization therapy in patients with ischemic cardiomyopathy: An acute pressure-volume loop study
Background: Response to cardiac resynchronization therapy (CRT) is hampered by the extent and location of left ventricular (LV) scar tissue. It is commonly advised to avoid scar tissue while placing the LV lead. However, whether individual patients benefit from this strategy remains unclear.Methods: Thirty-two CRT candidates with ischemic cardiomyopathy were enrolled from 2 successive clinical trials (TBS and E-pot study). Magnetic resonance imaging with late contrast enhancement was performed to assess location, degree and transmurality of LV scar tissue. Patients underwent invasive pressure-volume loop measurements to as...
Source: American Heart Journal - January 16, 2014 Category: Cardiology Authors: Gerben Jan de Roest, LiNa Wu, Carel C. de Cock, Matthijs L. Hendriks, Peter Paul H.M. Delnoy, Albert C. van Rossum, Cornelis P. Allaart Tags: Heart Failure Source Type: research

CHADS2 and CHA2DS2-VASc scores to predict morbidity and mortality in heart failure patients candidates to cardiac resynchronization therapy
Conclusion In CRT-D patients, pre-implant CHA2DS2-VASc score is an independent predictor of major clinical events at 30-month follow-up.
Source: Europace - December 16, 2013 Category: Cardiology Authors: Paoletti Perini, A., Bartolini, S., Pieragnoli, P., Ricciardi, G., Perrotta, L., Valleggi, A., Vergaro, G., Michelotti, F., Boggian, G., Sassone, B., Mascioli, G., Emdin, M., Padeletti, L. Tags: Pacing and resynchronization therapy Source Type: research

Multipoint left ventricular pacing improves acute hemodynamic response assessed with pressure-volume loops in cardiac resynchronization therapy patients
Backgound: Conventional cardiac resynchronization therapy (CRT) improves acute cardiac hemodynamics.Objective: To investigate if CRT with multipoint left ventricular (LV) pacing in a single coronary sinus branch (MultiPoint Pacing [MPP], St Jude Medical, Sylmar, CA) can offer further hemodynamic benefits to patients.Methods: Forty-four consecutive patients (80% men, New York Heart Association III, end-systolic volume 180 ± 77 mL, ejection fraction 27% ± 6%, and QRS duration 152 ± 17 ms) receiving a CRT device implant (Unify Quadra MP or Quadra Assura MP and Quartet LV lead, St Jude Medical) underwent intraoperative asse...
Source: Heart Rhythm - December 2, 2013 Category: Cardiology Authors: Carlo Pappone, Žarko Ćalović, Gabriele Vicedomini, Amarild Cuko, Luke C. McSpadden, Kyungmoo Ryu, Enrico Romano, Massimo Saviano, Mario Baldi, Alessia Pappone, Cristiano Ciaccio, Luigi Giannelli, Bogdan Ionescu, Andrea Petretta, Raffaele Vitale, Angeli Tags: Devices Source Type: research

Efficient preloading of the ventricles by a properly timed atrial contraction underlies stroke work improvement in the acute response to cardiac resynchronization therapy
Conclusion: Efficient preloading of the ventricles by a properly timed atrial contraction is responsible for a significant stroke work improvement in the acute CRT response.
Source: Heart Rhythm - August 7, 2013 Category: Cardiology Authors: Yuxuan Hu, Viatcheslav Gurev, Jason Constantino, Natalia Trayanova Tags: Experimental Source Type: research

Noninvasive Monitoring of Stroke Volume With Resynchronization Devices in Patients With Ischemic Cardiomyopathy
Conclusions: In CRT patients with chronic infarction and wall motion abnormalities, impedance is a valid parameter to estimate stroke volume and to guide optimization of CRT timing.
Source: Journal of Cardiac Failure - August 1, 2013 Category: Cardiology Authors: Michael Kühne, Mario Bocchiardo, Herbert Nägele, Beat Schaer, Michael Lippert, Christian Sticherling, Stefan Osswald Tags: Clinical Investigations Source Type: research

Optimisation of cardiac resynchronization therapy in clinical practice during exercise.
CONCLUSION: A potential increase in SV of 10 % can be achieved using Nexfin for optimisation of AV delay during exercise. A considerable number of patients showed benefit with lengthening of the AV delay during exercise. PMID: 23821492 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - July 3, 2013 Category: Cardiology Authors: Molenaar MM, Oude Velthuis B, Scholten MF, Stevenhagen JY, Wesselink WA, van Opstal JM Tags: Neth Heart J Source Type: research

Abstract 227: Prescribing Warfarin at Discharge for Heart Failure Patients without Atrial Fibrillation Findings from the Get With The Guidelines-Heart Failure Registry Poster Session II
Conclusions: Approximately 1 in 10 HF patients without AF or other documented indications are prescribed warfarin at discharge, and prescription rates vary widely across hospitals. Further research is needed to understand why anticoagulation is prescribed to patients with HF in the absence of documented indications.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Eapen, Z., Grau-Sepulveda, M., Fonarow, G., Heidenreich, P., Peterson, E., Hernandez, A. Tags: Poster Session II Source Type: research

Effect of atrioventricular and ventriculoventricular delay optimization on clinical and echocardiographic outcomes of patients treated with cardiac resynchronization therapy: A meta-analysis
Conclusion: The current literature suggests that routine AV and/or VV delay optimization has a neutral effect on clinical and echocardiographic outcomes based on pooled data from randomized and nonrandomized studies. Standardization of patient selection and optimization timing and method may help to further define the role of CRT device optimization.
Source: American Heart Journal - May 2, 2013 Category: Cardiology Authors: Dominique Auger, Ulas Hoke, Jeroen J. Bax, Eric Boersma, Victoria Delgado Tags: Curriculum in Cardiology Source Type: research

Prediction of long-term outcome of cardiac resynchronization therapy by acute pressure-volume loop measurements
Conclusion Invasive assessment of acute haemodynamics is a reliable tool to determine individual response to CRT. An acute increase in SW predicts long-term response to CRT with a higher accuracy than an acute increase in dP/dtmax, baseline QRS duration, and degree of LV mechanical dyssynchrony.
Source: European Journal of Heart Failure - February 20, 2013 Category: Cardiology Authors: de Roest, G. J., Allaart, C. P., Kleijn, S. A., Delnoy, P. P. H. M., Wu, L., Hendriks, M. L., Bronzwaer, J. G. F., van Rossum, A. C., de Cock, C. C. Tags: CRT Source Type: research

The Year in Review of Clinical Cardiac Electrophysiology
This past year saw multiple important advances in the field clinical cardiac electrophysiology. Seminal articles describing new anticoagulant drugs for stroke prevention in atrial fibrillation were published. New results that raise questions regarding the safety of dronedarone and several new promising techniques in AF ablation were described. Important articles that refine our understanding of the risk of sudden death among Wolff-Parkinson-White patients were published. In the basic and translational sciences, the application of gene therapy to the study and potential treatment of arrhythmias was described, whereas geneti...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - February 11, 2013 Category: Cardiology Source Type: research

Larger Interventricular Conduction Time Enhances Mechanical Response to Resynchronization Therapy
ConclusionsAn optimal acute response to CRT can be obtained by positioning the LV lead at the site associated with the maximum RV‐to‐LV conduction time. A significant correlation appears to exist between RV‐to‐LV conduction time and the improvement in systolic function with CRT.
Source: Pacing and Clinical Electrophysiology : PACE - January 10, 2013 Category: Cardiology Authors: LUIGI PADELETTI, PAOLO PIERAGNOLI, GIUSEPPE RICCIARDI, LAURA PERROTTA, ALESSANDRO P. PERINI, GINO GRIFONI, ILARIA RICCERI, MARGHERITA PADELETTI, VINCENZO LIONETTI, SERGIO VALSECCHI Tags: Original Article Source Type: research

Recent advances in management of atrial fibrillation in patients with heart failure
The objective of this review is to provide an overview of atrial fibrillation in HF, and the implications for management. Recent findings: At present there is no evidence that a rhythm control strategy may bring any long-term benefits in routine management of atrial fibrillation in HF. Recently, the procedure of pulmonary vein isolation has been shown to provide clinical and prognostic benefits in patients with atrial fibrillation and concomitant HF who remain symptomatic despite optimal medical therapy, including rate and rhythm control. A meta-analysis of patients with atrial fibrillation and symptomatic HF who had impla...
Source: Current Opinion in Cardiology - January 1, 2013 Category: Cardiology Tags: HEART FAILURE: Edited by Haissam Haddad Source Type: research