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Therapy: Cardiac Resynchronization Therapy

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Total 150 results found since Jan 2013.

New insights from a computational model on the relation between pacing site and CRT response
Conclusions</div>In these model simulations, the best cardiac function was obtained when pacing the mid-basal LV lateral wall, because of fastest recruitment of LV activation. This study illustrates how computer modeling can shed new light on optimizing pacing therapies for CRT. The results from this study may help to design new clinical studies to further investigate the importance of the pacing site for CRT response.</span>
Source: Europace - December 22, 2016 Category: Cardiology Source Type: research

MassDevice.com +5 | The top 5 medtech stories for November 14, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Final FDA rules clarify adverse event reporting for contract manufacturers The FDA last week issued final guidance for medical device companies on the requirements for reporting adverse events that walked back much of the burde...
Source: Mass Device - November 14, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Improved patient selection for cardiac resynchronization therapy by normalization of QRS duration to left ventricular dimension
ConclusionSince normalized QRSd reflects myocardial conduction properties, these findings suggest that myocardial conduction velocity rather than increased path length mainly determines response to CRT. Normalizing QRSd to LV dimension might provide a relatively simple method to improve patient selection for CRT.
Source: Europace - October 5, 2016 Category: Cardiology Source Type: research

Mortality After Atrioventricular Nodal Radiofrequency Catheter Ablation With Permanent Ventricular Pacing in Atrial Fibrillation: Outcomes From a Controlled Nonrandomized Study Original Article
Conclusions— In sick AF patients with multiple comorbidities, AVNA with permanent ventricular pacing for rate control seems safe during follow-up and may be associated with lower mortality.
Source: Circulation: Arrhythmia and Electrophysiology - June 29, 2016 Category: Cardiology Authors: Garcia, B., Clementy, N., Benhenda, N., Pierre, B., Babuty, D., Olshansky, B., Fauchier, L. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Atrial Fibrillation Original Article Source Type: research

Bifocal left ventricular stimulation or the optimal left ventricular stimulation site in cardiac resynchronization therapy: a pressure-volume loop study
Conclusion Stimulation at the optimal LV site showed a significantly higher pump function improvement compared with bifocal LV stimulation. Mechanical activation at the optimal LV site was significantly more delayed compared with the non-optimal LV site. In general, these results suggest that implantation of a second LV lead yields no additional benefit over implantation of one optimally placed LV lead. However, a bifocal approach might be beneficial in the individual patient.
Source: Europace - June 28, 2016 Category: Cardiology Authors: de Roest, G. J., Wu, L., de Cock, C. C., Delnoy, P.-P. H. M., Hendriks, M. L., van Rossum, A. C., Allaart, C. P. Tags: Pacing and resynchronization therapy Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter Defibrillators over Time in Ischemic and Dilated Cardiomyopathy Patients
ConclusionThese changes in clinical practice with a shift to primary prevention and rise in non‐ICM implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real‐life cohort.
Source: Pacing and Clinical Electrophysiology : PACE - June 6, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, CHRISTIAN STICHERLING, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: ORIGINAL Source Type: research

Dynamic Changes in High ‐Sensitivity Cardiac Troponin I Are Associated with Dynamic Changes in Sum Absolute QRST Integral on Surface Electrocardiogram in Acute Decompensated Heart Failure
ConclusionPatient‐specific time‐varying changes in the surface ECG scalar measure of global electrical heterogeneity, as measured by SAI QRST, and in myocardial injury as measured by hsTnI, are independently and directly associated with each other, likely reflecting a common underlying mechanism.
Source: Annals of Noninvasive Electrocardiology - June 5, 2016 Category: Cardiology Authors: Larisa G. Tereshchenko, Albert Feeny, Erica Shelton, Thomas Metkus, Andrew Stolbach, Ernest Mavunga, Shannon Putman, Frederick K. Korley Tags: Original Article Source Type: research

Dynamic Changes in High‐Sensitivity Cardiac Troponin I Are Associated with Dynamic Changes in Sum Absolute QRST Integral on Surface Electrocardiogram in Acute Decompensated Heart Failure
ConclusionPatient‐specific time‐varying changes in the surface ECG scalar measure of global electrical heterogeneity, as measured by SAI QRST, and in myocardial injury as measured by hsTnI, are independently and directly associated with each other, likely reflecting a common underlying mechanism.
Source: Annals of Noninvasive Electrocardiology - June 5, 2016 Category: Cardiology Authors: Larisa G. Tereshchenko, Albert Feeny, Erica Shelton, Thomas Metkus, Andrew Stolbach, Ernest Mavunga, Shannon Putman, Frederick K. Korley Tags: Original Article Source Type: research

PM101 Impact of Right Ventricular Stroke Work Index on the Echocardiographic and Clinical Response to Cardiac Resynchronization Therapy
Right ventricular (RV) dysfunction is considered a major determinant of outcome in patients with moderate-to-severe heart failure (HF). Baseline RV function may play a role in determining the left ventricular response to CRT. The RV stroke work index (RVSWI) calculates RV workload and contractility based on invasive hemodynamics. However there is no data about the value of basal RVSWI in predicting the left ventricular response to CRT.
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: N. Arat, E. Ozenc, O. Yildiz, S. Usalp, O. Demiroz, C. Ciftci Tags: Poster Abstract Source Type: research

HRS 2016 roundup: Leadless pacers at the fore
Medtronic (NYSE:MDT) and St. Jude Medical (NYSE:STJ), aiming to distinguish their respective leadless pacemaker offerings, presented new data last week in San Francisco at the Heart Rhythm Society’s annual meeting. St. Jude said a subset of data from the Leadless II trial showed that its Nanostim device was was successfully retrieved in 14 patients up to 3.2 years after implantation, with no serious adverse events. “We’ve now shown that for patients requiring device upgrades or new leadless pacing options, late retrievability – even up to 3 years – is possible with the Nanostim leadless pacemak...
Source: Mass Device - May 9, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Cardiovascular Clinical Trials Boston Scientific Cardiac Rhythm Management HRS 2016 Medtronic St. Jude Medical Source Type: news

Simultaneous His Bundle and Left Ventricular Pacing for Optimal Cardiac Resynchronization Therapy Delivery: Acute Hemodynamic Assessment by Pressure-Volume Loops Original Articles
Conclusions— Standard right ventricular apex+LV and LV-only pacing enhanced systolic function and LV synchrony at individually optimized AVD close to the measured intrinsic P-H interval. By contrast, HIS+LV pacing yielded improvements, regardless of AVD setting. These findings support the hypothesis of the crucial role of intrinsic right ventricular conduction in optimal cardiac resynchronization therapy delivery.
Source: Circulation: Arrhythmia and Electrophysiology - May 8, 2016 Category: Cardiology Authors: Padeletti, L., Pieragnoli, P., Ricciardi, G., Innocenti, L., Checchi, L., Padeletti, M., Michelucci, A., Picariello, F., Valsecchi, S. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Congenital Heart Disease, Heart Failure, Pacemaker Original Articles Source Type: research

The influence of right ventricular stimulation on acute response to cardiac resynchronisation therapy.
CONCLUSION: The haemodynamic effect of addition of RVapex stimulation to LV stimulation differs widely among patients receiving CRT. Poor RV function is associated with poor response to LV but not BiV stimulation. PMID: 26649436 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - December 9, 2015 Category: Cardiology Authors: Wu L, de Roest GJ, Hendriks ML, van Rossum AC, de Cock CC, Allaart CP Tags: Neth Heart J Source Type: research

MassDevice.com +3 | The top 3 medtech stories for November 24, 2015
Say hello to MassDevice +3, a bite-sized view of the top three medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 3 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry.   3. Ocular Therapeutix launches another pivotal for Dextenza eye drug-device combo Ocular Therapeutix said today that it launched another pivotal trial for its Dextenza drug-device combination, its 2nd study of the treatment for an allergic conjunctivitis indication. Bedford, Mass.-based Ocular Th...
Source: Mass Device - November 24, 2015 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 3 Source Type: news

Non-invasive hemodynamic analysis in cardiac resynchronization therapy patients wearing quadripolar left ventricular leads: the importance of pacing electrode selection.
CONCLUSION: Our study demonstrates that different bipolar pacing configurations, even if arising from a single CS branch, substantially modify the hemodynamic effect of LV pacing in CRT patients. Moreover, the non-invasive hemodynamic analysis suggests the better pacing configuration should be established individually and could represent an important issue in optimizing CRT during follow-up. PMID: 25275712 [PubMed - indexed for MEDLINE]
Source: Minerva Cardioangiologica - November 18, 2015 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research