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Total 342 results found since Jan 2013.
Mortality of bullous pemphigoid in Singapore: risk factors and causes of death in 359 patients seen at the National Skin Centre.
CONCLUSION: This study confirmed an increased 3-year mortality rate for BP patients in Singapore. Risk factors for increased mortality include medical co-morbidities, especially neurological, cardiac and renal diseases. Treatment with combination therapy, including the use of low to moderate dose corticosteroid, appeared to decrease mortality risk in BP patients. This article is protected by copyright. All rights reserved.
PMID: 24372558 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - December 24, 2013 Category: Dermatology Authors: Cai SC, Allen JC, Lim YL, Chua SH, Tan SH, Tang MB Tags: Br J Dermatol Source Type: research
Systemic Corticosteroids in Acute Chest Syndrome: Friend or Foe?
Summary: Acute chest syndrome(ACS) is the most common pulmonary complication of sickle cell disease (SCD), the second most common cause of hospitalization and the primary cause of death in patients with sickle cell disease. Its highest prevalence is in early childhood. The pathogenesis of ACS is unknown but many predisposing conditions and mechanisms have been implicated including infections, pulmonary fat embolism, asthma and ischemic reperfusion injury. These conditions are associated with inflammation and therefore, the use of corticosteroids has been advocated because of their anti-inflammatory properties. Although, si...
Source: Paediatric Respiratory Reviews - November 25, 2013 Category: Respiratory Medicine Authors: Folasade Ogunlesi, Matthew M. Heeney, Anastassios C. Koumbourlis Tags: Mini-Symposium: Controversies in the evaluation and treatment of sickle cell disease Source Type: research
Factors Associated with Major Cardiovascular Events in Patients with Systemic Necrotizing Vasculitides: Results of a Longterm Followup Study.
CONCLUSION: These results suggest that factors associated with a higher MCVE risk in patients with SNV are NCEP/ATP III-defined high-risk status and BMI > 30 kg/m(2). Carotid IMT could help identify patients with SNV at risk of early MCVE.
PMID: 24584925 [PubMed - as supplied by publisher]
Source: J Rheumatol - March 1, 2014 Category: Rheumatology Authors: Terrier B, Chironi G, Pagnoux C, Cohen P, Puéchal X, Simon A, Mouthon L, Guillevin L, for the French Vasculitis Study Group Tags: J Rheumatol Source Type: research
Pheochromocytoma crisis resulting in acute heart failure and cardioembolic stroke in a 37-year-old man
A previously healthy, 37-year-old man presented to his primary care physician with new-onset hypertension, cough, and dyspnea. He was initially diagnosed with asthma and was treated with inhalation corticosteroids. Despite treatment, his symptoms worsened over a 3-month period. Although previously athletic, he developed exercise intolerance, orthopnea, and paroxysmal nocturnal dyspnea. His symptoms prompted admission to a community hospital to rule out pulmonary embolism. Contrast computed tomography of the chest instead demonstrated a 5.3 × 4.8-cm left adrenal tumor ().
Source: Surgery - January 9, 2013 Category: Surgery Authors: Jenny K. Cohen, Robin M. Cisco, Anouk Scholten, Elliot Mitmaker, Quan-Yang Duh Tags: Images in Surgery Source Type: research
Headaches in brain tumor patients: primary or secondary?
CONCLUSION: Our literature review revealed that brain tumor headache uncommonly presents with classic brain tumor headache characteristics and often satisfies criteria for a primary headache category such as migraine or tension-type. Thus, clinicians may miss headaches due to brain tumors in following ICHD-3 criteria, and the distinction between primary and secondary headache disorders may not be so clear-cut.
PMID: 24697234 [PubMed - in process]
Source: Headache - April 1, 2014 Category: Neurology Authors: Nelson S, Taylor LP Tags: Headache Source Type: research
Paroxysmal Dysarthria and Ataxia after Treatment of Brainstem Encephalitis (P6.053)
CONCLUSIONS: Paroxysmal dysarthria and ataxia is most often recognized as a complication of multiple sclerosis, but it can occur in other neurologic diseases with midbrain lesions near or involving the red nucleus. Effective treatments include carbamazepine, acetazolamide, lamotrigine, and phenytoin.Study Supported by: N/A.Disclosure: Dr. Klaas has nothing to disclose. Dr. Boes has nothing to disclose. Dr. Aksamit has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Klaas, J., Boes, C., Aksamit, A. Tags: Movement Disorders: Miscellaneous Ataxias Source Type: research
Do Not Forget Susac Syndrome in Patients with Unexplained Acute Confusion (P6.303)
CONCLUSIONS: We report two patients evaluated within one month of each other who presented with acute confusion associated with MRI and CSF abnormalities and were eventually diagnosed with Susac syndrome. Susac syndrome remains under-diagnosed and should be included in the differential diagnosis of patients with unexplained confusional state associated with CSF pleocytosis/proteinorrachia and MRI callosal abnormalities.Disclosure: Dr. Star has nothing to disclose. Dr. Bruzzone has nothing to disclose. Dr. De Alba has nothing to disclose. Dr. Gill has nothing to disclose. Dr. Schneck has received personal compensation in an...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Star, M., Bruzzone, M., De Alba, F., Gill, R., Schneck, M., Biller, J. Tags: Neuro-ophthalmology/Neuro-otology II Source Type: research
FDA Orders New Warning for Epidural Steroids
(MedPage Today) -- Injectable corticosteroids must now carry a new label warning about the risks of severe adverse effects from epidural injections including death, stroke, and permanent blindness and paralysis, the FDA said.
Source: MedPage Today Geriatrics - April 24, 2014 Category: Geriatrics Source Type: news
Spinal Corticosteroids Run Risk of Severe Neuro EffectsSpinal Corticosteroids Run Risk of Severe Neuro Effects
The FDA has announced that injections given to treat neck and back pain and radiating pain in the arms and legs may result, on rare occasions, in blindness, stroke, paralysis, and death. News Alerts
Source: Medscape Neurology and Neurosurgery Headlines - April 24, 2014 Category: Neurology Tags: Neurology & Neurosurgery News Alert Source Type: news
Epidural Corticosteroid Injections Pose Risk for Neurological Problems (FREE)
By Kristin J. Kelley
Injectable corticosteroids given via epidural to treat back and neck pain may cause "rare but serious" complications — paralysis, stroke, vision loss, and death …
Source: Physician's First Watch current issue - April 24, 2014 Category: Primary Care Source Type: news
Epidural Corticosteroid Injection: Drug Safety Communication - Risk of Rare But Serious Neurologic Problems
Injection of corticosteroids into the epidural space of the spine may result in loss of vision, stroke, paralysis, and death.
Source: FDA MedWatch - April 23, 2014 Category: American Health Source Type: news
Study shows insufficient decrease in wound complications with sutured versus stapled skin closure in gastrointestinal operations
Commentary on: Tsujinaka T, Yamamoto K, Fujita J, et al.. Subcuticular sutures versus staples for skin closure after open gastrointestinal surgery: a phase 3, multicentre, open-label, randomised controlled trial. Lancet 2013;382:1105–12. Context Postoperative wound complications can occur in 9–26% of gastrointestinal operations.1–3 Skin closure with subcuticular sutures in clean operations, such as caesarean sections, are associated with decreased wound complications and increased patient satisfaction when compared with skin closure using staples.4 5 Whether these results are applicable to clean–con...
Source: Evidence-Based Medicine - May 19, 2014 Category: Internal Medicine Authors: Vo, H., Kin, C. Tags: Patients, Clinical trials (epidemiology), Immunology (including allergy), Drugs: cardiovascular system, Stroke, Dermatology, Diabetes, Injury Therapeutics Source Type: research
Steroid treatment can improve the impaired quality of life of patients with acquired idiopathic generalized anhidrosis
This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - July 24, 2014 Category: Dermatology Authors: A. Fukunaga, M. Hatakeyama, M. Tsujimoto, Y. Oda, K. Washio, C. Nishigori Tags: Correspondence Source Type: research
Steroid treatment can improve the impaired quality of life of patients with acquired idiopathic generalized anhidrosis.
This article is protected by copyright. All rights reserved.
PMID: 25060903 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - July 24, 2014 Category: Dermatology Authors: Fukunaga A, Hatakeyama M, Tsujimoto M, Oda Y, Washio K, Nishigori C Tags: Br J Dermatol Source Type: research
Treating gerstmann's syndrome with natalizumab
We present video, MRI and pathological evidence of the case of a 30 year old woman who developed Gerstmann's syndrome as a result of a tumefactive multiple sclerosis (MS) lesion affecting the left cerebral hemisphere. Intravenous corticosteroids failed to stop rapid enlargement of the index lesion and occurrence of additional hemispheric lesions leading to clinical deterioration.
Brain biopsy confirmed the diagnosis of MS. Strong contrast enhancement of the lesions prompted us to start treatment with natalizumab 300 mg i.v. every four weeks leading to sustained disease remission over a 14 month follow-up period though comp...
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 9, 2014 Category: Neurosurgery Authors: Gnanapavan, S., Zane, J., Kelly, P., Sakthivel, G., Klaus, S. Tags: Abstracts Source Type: research
