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Therapy: Palliative

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Total 267 results found since Jan 2013.

Definitive chemoradiotherapy for advanced cervical cancer: should it be different in the elderly?
Conclusions Despite advanced age, more than 60% of pts underwent complete CRT treatment. Thus, age should not be the only factor to guide therapeutic decisions in CC. Carboplatin was better tolerated
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - June 20, 2015 Category: OBGYN Source Type: research

Hospice and Palliative Medicine Clinician Views of Deactivation of Ventricular Assist Devices at the End of Life
Left ventricular assist devices (LVADs) provide circulatory support to patients with advanced heart failure. These devices are used as a temporary bridge to recovery, bridge to cardiac transplantation, or as destination therapy (DT)—where the patient will have the device in situ for the remainder of his/her life. Compared to medical management alone, LVAD-DT often improves survival and quality of life for patients with severe heart failure.1 However, patients with LVADs may experience a host of challenges including a catastrophic event (e.g., stroke, hemorrhage, infection), a concurrent slow decline in health (e.g., righ...
Source: Journal of Pain and Symptom Management - May 26, 2015 Category: Palliative Care Authors: Keith M. Swetz, Sara E. Wordingham, Matthew H. Armstrong, Katlyn E. Koepp, Abigale L. Ottenberg Tags: Letter Source Type: research

Risk of type 2 diabetes mellitus in female breast cancer patients treated with morphine: a retrospective population-based time-dependent cohort study
A key element of the palliative care of cancer patients is the management of chronic pain [1]. Opioids continue to be a mainstay in the management of cancer pain in all treatment guidelines [2], and morphine is regarded as the “gold standard” [3–6]. Considered as broad-spectrum analgesics, opioids have multiple side effects and potential complications [7]. Our previous studies indicated that morphine treatment is associated with subdural hemorrhage [8], pulmonary embolism [9], and acute coronary syndrome [10] in cancer patients, as well as increased stroke incidence in prostate cancer patients [11].
Source: Diabetes Research and Clinical Practice - October 12, 2015 Category: Endocrinology Authors: Szu-Pang Yang, Chih-Hsin Muo, I-Kuan Wang, Yen-Jung Chang, Shih-Wei Lai, Cynthia Wei-Sheng Lee, Donald E. Morisky Source Type: research

The Evolution of an Inpatient Palliative Care Consultation Service in an Urban Teaching Hospital.
CONCLUSION: We describe the evolution of palliative care in a safety-net hospital. Medicine services which are largely resident run adopted early. Specialty services that are attending driven adopted later. We believe house staff and nurses were the initial change agents. The number of consultations increased when house staff and students began rotating on the service suggesting unmet demand due to the limited supply of providers. PMID: 26543069 [PubMed - as supplied by publisher]
Source: The American Journal of Hospice and Palliative Care - November 5, 2015 Category: Palliative Care Authors: Liu OY, Malmstrom T, Burhanna P, Rodin MB Tags: Am J Hosp Palliat Care Source Type: research

Reversible hemiparesis in a patient with migraine.
This report is adapted from paineurope 2014; Issue 1, Haymarket Medical Publications Ltd., and is presented with permission. paineurope is provided as a service to pain management by Mundipharma International, Ltd., and is distributed free of charge to health care professionals in Europe. Archival issues can be accessed via the Web site: http://www.paineurope.com at which European health professionals can register online to receive copies of the quarterly publication. PMID: 25166776 [PubMed - indexed for MEDLINE]
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 20, 2015 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Occupational Therapy: Cost-Effective Solutions for Changing Health System Needs
This article aligns the discussion of health system transformation with literature identifying the cost-effectiveness of occupational therapy in Canada.
Source: Healthcare Quarterly - January 30, 2013 Category: Global & Universal Source Type: research

Optimising palliative and end-of-life care within care home settings
Background The World Health Organization (WHO) has defined palliative care as an approach that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment and treatment of pain and other problems, physical, psychosocial and spiritual.1 Globally, it is estimated that every year over 20 million people will require palliative care at the end of life. Of these 69% are adults over 60 years. These older population, who make up the vast majority of residents w...
Source: Evidence-Based Nursing - December 15, 2015 Category: Nursing Authors: Mitchell, G., Twycross, A. Tags: End of life decisions (geriatric medicine), Drugs: cardiovascular system, Dementia, Pain (neurology), EBN Opinion, Stroke, End of life decisions (palliative care), Hospice, Memory disorders (psychiatry), End of life decisions (ethics) Source Type: research

Community palliative care use by dementia sufferers may reduce emergency department use at end of life
Commentary on: Rosenwax L, Spilsbury K, Arendts G, et al. Community-based palliative care is associated with reduced emergency department use by people with dementia in their last year of life: a retrospective cohort study. Palliat Med 2015;29:727–36. Implications for practice and research We need to better understand how community palliative care should be organised and delivered to optimise well-being for the dementia population. Research is needed to explore and explain the nature of the relationship between community palliative care and emergency department (ED) use. More work is needed to examine which palliativ...
Source: Evidence-Based Nursing - December 15, 2015 Category: Nursing Authors: Wright, D. K., Vandyk, A. D. Tags: End of life decisions (geriatric medicine), Care of the older person, Dementia, Pain (neurology), Stroke, End of life decisions (palliative care), Hospice, Memory disorders (psychiatry), End of life decisions (ethics) Source Type: research

“This Was Not What I Had in Mind,” and Other Palliative Challenges Encountered in Left Ventricular Assist Device (LVAD) Care (TH321)
With the evolution and growing availability of mechanical circulatory support (MCS) technology for patients with advanced heart failure come new frontiers for palliative care (PC) teams. Although data demonstrates that MCS devices, including left ventricular assist devices (LVADs), can improve survival and quality-of-life for patients with advanced heart failure, patients remain at risk for catastrophic events, like stroke or hemorrhage, persistent functional decline, or progression of other life-threatening medical conditions.
Source: Journal of Pain and Symptom Management - January 29, 2016 Category: Palliative Care Authors: J. Hunter Groninger, George Ruiz, Joan Panke, Anne Kelemen Source Type: research

Palliative care in India: Situation assessment and future scope
SS Kar, L Subitha, S IswaryaIndian Journal of Cancer 2015 52(1):99-101Palliative care is an approach that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through prevention and relief of suffering by means of early identification, assessment and treatment of pain, and other problems – physical, psychosocial, and spiritual. It is estimated that in India the total number of people who need palliative care is likely to be 5.4 million people a year. Though palliative care services have been in existence for many years, India ranks at the bot...
Source: Indian Journal of Cancer - February 3, 2016 Category: Cancer & Oncology Authors: SS KarL SubithaS Iswarya Source Type: research

Predictors of place of death in South West Scotland 2000-2010: Retrospective cohort study.
CONCLUSION: The proportion of people dying at home fell during our survey. Place of death was strongly associated with age, calendar year and cause of death. A mismatch remains between stated preference for place of death and where death occurs. PMID: 26857358 [PubMed - as supplied by publisher]
Source: Palliative Medicine - February 8, 2016 Category: Palliative Care Authors: Black H, Waugh C, Munoz-Arroyo R, Carnon A, Allan A, Clark D, Graham F, Isles C Tags: Palliat Med Source Type: research

Neurologists as primary palliative care providers: Communication and practice approaches
Purpose of review: To present current knowledge and recommendations regarding communication tasks and practice approaches for neurologists as they practice primary palliative care, including discussing serious news, managing symptoms, aligning treatment with patient preferences, introducing hospice/terminal care, and using the multiprofessional approach. Recent findings: Neurologists receive little formal palliative care training yet often need to discuss prognosis in serious illness, manage intractable symptoms in chronic progressive disease, and alleviate suffering for patients and their families. Because patients with ...
Source: Neurology Clinical Practice - February 15, 2016 Category: Neurology Authors: Creutzfeldt, C. J., Robinson, M. T., Holloway, R. G. Tags: All Clinical Neurology, Prognosis, All Cerebrovascular disease/Stroke, Palliative care Review Source Type: research

Repeated Aortic Balloon Valvuloplasty in Elderly Patients With Aortic Stenosis Who Are Not Candidates for Definitive Treatment.
CONCLUSION: BAV is associated with poor long-term clinical outcome. However, when no other therapeutic options are feasible, a strategy of repeated palliative BAV appears to be safe and is potentially associated with improved clinical outcomes. PMID: 26378413 [PubMed - in process]
Source: The Journal of Invasive Cardiology - March 11, 2016 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Mucor Thrombus
Conclusions The endovascular placement of an expandable stent in the setting of angioinvasive mucormycosis restored good cerebral blood flow in a proximal internal carotid artery occlusion. The patient’s aphasia resolved following this intervention. Artifacts of CT angiography may result in the overestimation of acute arterial occlusions. Endovascular carotid stenting may be a palliative measure in the setting of angioinvasive rhino-cerebro-orbital mucormycosis.
Source: Neurocritical Care - March 31, 2016 Category: Neurology Source Type: research

Long-term cardiovascular outcomes and overall survival of early-stage breast cancer patients with early discontinuation of trastuzumab: a population-based study
Abstract We critically examined long-term cardiovascular (CV) outcomes and overall survival (OS) of breast cancer (BC) patients who had cardiotoxicity during adjuvant trastuzumab treatment requiring discontinuation in a population-based sample. This was a retrospective cohort of early-stage BC patients diagnosed before 2010 and treated with trastuzumab in Ontario. Patients were stratified based on trastuzumab doses received: 1–8, 9–15, ≥16 (therapy completion). Time-dependent multivariable Cox models were used to analyze primary endpoint OS, and the following composite endpoints: hospitalization/emergency ro...
Source: Breast Cancer Research and Treatment - June 5, 2016 Category: Cancer & Oncology Source Type: research