Filtered By:
Specialty: Cardiology
Condition: Cardiomyopathy
Education: Study

This page shows you your search results in order of date.

Order by Relevance | Date

Total 256 results found since Jan 2013.

Suberosin Alleviates Thiazolidinedione-Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4-LPCAT3 and PI3K-AKT Signaling Pathways
In this study, we investigated the anti-ferroptosis effects of suberosin (SBR; a prenylated coumarin) in diabetic Sprague Dawley rats. Further, we assessed the effects of co-administration of SBR (30 and 90 mg/kg/day) with thiazolidinedione (TZ at 15 mg/kg) to mitigate TZ-induced cardiomyopathy in diabetic rats. Our results showed that cardiac output, stroke volume, left ventricle systolic and diastolic pressures were aggravated in diabetic rats treated with TZ alone after 4 weeks. TZ treatments induced ferroptosis as well as marked histoarchitecture disarrangements in rat cardiomyocytes. The study found that optimizing vo...
Source: Cardiovascular Toxicology - September 7, 2023 Category: Cardiology Authors: Shabnoor Iqbal Farhat Jabeen Ivan Kahwa Timothy Omara Source Type: research

Signaling Pathways Associated with Prior Cardiovascular Events in Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy. A subset of patients experience major adverse cardiovascular event (MACE) including arrhythmias, stroke, and heart failure. However, molecular mechanisms underlying MACE in HCM are still not well understood. We therefore conducted a multicenter case-control study of patients with HCM comparing those with and without prior history of MACE to identify dysregulated signaling pathways through plasma proteomics profiling.
Source: Journal of Cardiac Failure - August 7, 2023 Category: Cardiology Authors: Charlotte Lee, Lusha W. Liang, Kohei Hasegawa, Mathew S. Maurer, Albree Tower-Rader, Michael A. Fifer, Muredach Reilly, Yuichi J. Shimada Source Type: research

Gender Differences in Atrial Fibrosis and Cardiomyopathy Assessed by Left Atrial Low-Voltage Areas During Catheter Ablation of Atrial Fibrillation
This study aimed to delineate gender differences in the prevalence, predictors, and prognostic impact of left atrial low-voltage areas (LVAs). This observational study included 1,488 consecutive patients who underwent initial ablation for AF. Voltage mapping was performed after pulmonary vein isolation during sinus rhythm.
Source: The American Journal of Cardiology - July 21, 2023 Category: Cardiology Authors: Masaharu Masuda, Yasuhiro Matsuda, Hiroyuki Uematsu, Ayako Sugino, Hirotaka Ooka, Satoshi Kudo, Subaru Fujii, Mitsutoshi Asai, Osamu Iida, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takuya Tsujimura, Yosuke Hata, Taku Toyoshima, Naoko Higashino, Sho Source Type: research

Risk of cardioembolic ischemic events and relation to atrial fibrillation/flutter in patients with arrhythmogenic cardiomyopathy during a long-term follow-up
This study sought to determine the occurrence of cardioembolic ischemic events (CIEs) in ACM patients and to identify clinical and imaging predictors of CIEs.
Source: International Journal of Cardiology - July 21, 2023 Category: Cardiology Authors: Elisabetta Toso, Francesca De Lio, Pier Paolo Bocchino, Claudia Raineri, Francesco Fioravanti, Elena Maria Richiardi, Gianluca Marcelli, Tania Sacco, Carla Giustetto, Fiorenzo Gaita Source Type: research

Cardiovascular Effects of Cannabinoids
Cardiol Rev. 2023 Jun 29. doi: 10.1097/CRD.0000000000000566. Online ahead of print.ABSTRACTMarijuana is now one of the most widely used substances in the United States that has been rising in prevalence given increasing legalization and recreational and medical usage. Despite its widespread use, there have been increasing concerns regarding the cardiovascular safety of marijuana. Recent studies have found a link between marijuana use and the development of cardiovascular disease. Most notably, marijuana has been found to be associated with various cardiac complications, including atherosclerosis, myocardial infarction, str...
Source: Atherosclerosis - June 29, 2023 Category: Cardiology Authors: Andy Wang Subo Dey Sarah Subhan Jay Patel William H Frishman Wilbert S Aronow Source Type: research

A causal relationship between irritability and cardiovascular diseases: a Mendelian randomization study
CONCLUSION: Our findings support the first genetic evidence of the causality of genetically predicted irritability with the risk of developing into CVDs. Our results deliver a viewpoint that more early active interventions to manage an individual's anger and related unhealthy lifestyle habits are needed to prevent the occurrence of adverse cardiovascular events.PMID:37324625 | PMC:PMC10267866 | DOI:10.3389/fcvm.2023.1174329
Source: Atherosclerosis - June 16, 2023 Category: Cardiology Authors: Dihui Cai Yin Fu Yongfei Song Hui Lin Yanna Ba Jiangfang Lian Source Type: research

Long ‐term success of a multi‐electrode substrate mapping and ablation strategy versus a classic single tip mapping and ablation strategy for ventricular tachycardia ablation in patients with ischemic cardiomyopathy
ConclusionsIn patients with ischemic cardiomyopathy, a HD substrate mapping, and ablation strategy did not lead to higher VT-free survival and shock-free survival compared to a single tip mapping and ablation strategy. In this study, only LVF is an independent predictor for VT recurrence. Anterior infarct location and age predict recurrent ICD shocks.
Source: Pacing and Clinical Electrophysiology : PACE - June 1, 2023 Category: Cardiology Authors: Jippe C. Balt, Bob G. S. Abeln, Bakhtawar K. Mahmoodi, Vincent F. Dijk, Maurits C. E. F. Wijffels, Lucas V. A. Boersma Tags: ELECTROPHYSIOLOGY Source Type: research

Substances of abuse and cardiovascular risk: cannabinoids
G Ital Cardiol (Rome). 2023 Jun;24(6):455-465. doi: 10.1714/4041.40205.ABSTRACTProgressive legalization for medical conditions or recreational use has led to an increased use of cannabis and synthetic cannabinoids over the past years. Most consumers are young and healthy, without cardiovascular risk factors; however, this population is expected to include older individuals. Thus, concerns have arisen about safety and short- and long-term potential adverse effects, with special emphasis on vulnerable groups. Studies show that cannabis might be linked with thrombosis, inflammation, and atherosclerosis, and many reports have ...
Source: Atherosclerosis - May 25, 2023 Category: Cardiology Authors: Maurizio G Abrignani Francesco Ciccirillo Pier Luigi Temporelli Arturo Cesaro Giulio Binaghi Alessandro Maloberti Chiara Cappelletto Fabrizio Oliva Carmine Riccio Pasquale Caldarola Domenico Gabrielli Furio Colivicchi Source Type: research

Po-05-185 prediction and risk of atrial fibrillation in patients with hypertrophic cardiomyopathy: a danish nationwide cohort study
Hypertrophic cardiomyopathy (HCM) can be associated with serious complications such as heart failure, atrial fibrillation (AF) and sudden cardiac death. The treatment of AF in HCM patients can be challenging since AF often aggravates symptoms and increases the risk of stroke. Little is known on which factors contribute to the development of AF in these patients.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Christopher Z örner, Jannik L. Pallisgaard, Anne-Marie Schjerning, Morten K. Jensen, Jacob Tønnesen, Lise D. Vestergaard, Peter Vibe Rasmussen, Gunnar Gislason, Morten L. Hansen Source Type: research

Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Systematic Review and Meta-analysis of Anticoagulation Strategy
ConclusionsCompared with VKAs, a DOAC-based strategy might represent an effective and safe strategy regarding all-cause mortality, major/life-threatening bleeding complications, and TEs in HCM patients with concomitant AF. However, further prospective studies are necessary to reinforce a DOAC-based anticoagulation strategy in this population.
Source: American Journal of Cardiovascular Drugs - April 15, 2023 Category: Cardiology Source Type: research

Factors influencing left ventricular thrombus resolution and its significance on clinical outcomes
ConclusionsThis study suggests that LVT resolution is an important predictor for favourable clinical outcomes. LVEF improvement failure interfered with LVT resolution and appeared to be a crucial factor for LVT recurrence. After LVT resolution, continuation of anticoagulation did not seem to impact LVT recurrence and the prognosis.
Source: ESC Heart Failure - April 4, 2023 Category: Cardiology Authors: Se ‐Eun Kim, Chan Joo Lee, Jaewon Oh, Seok‐Min Kang Tags: Original Article Source Type: research

The Impact of Complete Revascularization in Symptomatic Severe Left Ventricular Dysfunction between Coronary Artery Bypass Graft and Percutaneous Coronary Intervention
CONCLUSIONS: In patients with symptomatic (NYHA class ≥ 3) severe LV dysfunction and CAD, CABG brought less HF admission when compared to patients in the PCI group, but this did not differ when compared to the complete revascularization subgroup. Therefore, an extensive revascularization, achieved by CABG or PCI, is associated with a lower HF hospitalization rate during the 3-yearfollow-up period in such populations.PMID:36896424 | PMC:PMC9991473 | DOI:10.1155/2023/9226722
Source: Cardiology Research and Practice - March 10, 2023 Category: Cardiology Authors: Hsiu-Yu Fang Yen-Nan Fang Yin-Chia Chen Jiunn-Jye Sheu Wei-Chieh Lee Source Type: research