Clinical Phenotypes and Age-Related Differences in Presentation, Treatment, and Outcome of Heart Failure with Preserved Ejection Fraction: A Vietnamese Multicenter Research
Cardiol Res Pract. 2021 Jan 15;2021:4587678. doi: 10.1155/2021/4587678. eCollection 2021.ABSTRACTBACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a rising health problem with heterogeneous presentation and no evidence-based treatment. While Southeast Asia reported the highest mortality and morbidity among Asian population, little is known about the Vietnamese population, including patient characteristics, prescribing pattern and mortality rate.METHODS: We conducted an observational study on 477 patients diagnosed with HFpEF from seven hospitals in Southern Vietnam from January 2019 to December 2019.RES...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Ngoc-Thanh-Van Nguyen Diep Tuan Tran Pham Le An Sy Van Hoang Hoai-An Nguyen Hoa Ngoc Chau Source Type: research

Corrigendum to "Comparison of the CAMI-NSTEMI and GRACE Risk Model for Predicting In-Hospital Mortality in Chinese Non-ST-Segment Elevation Myocardial Infarction Patients"
Cardiol Res Pract. 2021 Feb 10;2021:5137403. doi: 10.1155/2021/5137403. eCollection 2021.ABSTRACT[This corrects the article DOI: 10.1155/2020/2469281.].PMID:33628488 | PMC:PMC7896849 | DOI:10.1155/2021/5137403 (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Peng Wang Hongliang Cong Ying Zhang Yujie Liu Source Type: research

Association between Serum Adiponectin and Atrial Fibrillation: A Case-Control Study Stratified by Age and Gender
Cardiol Res Pract. 2021 Feb 10;2021:6633948. doi: 10.1155/2021/6633948. eCollection 2021.ABSTRACTBACKGROUND: Circulating adiponectin has been suggested to be associated with atrial fibrillation (AF). However, whether the association differs by age and gender remains unknown. We performed a case-control study to evaluate the above association.METHODS: AF patients who underwent 24-hour long-range 12-channel electrocardiogram examination at our center were included in this study, and people with normal sinus rhythm (NSR) were included as controls. All participants underwent echocardiography and heart rate variability tests. B...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Tongjian Zhu Zhuo Wang Songyun Wang Wei Hu Hui Chen Jing Xie Meng Wang Kezhong Ma Hong Jiang Source Type: research

Impact of Prone Position on 12-Lead Electrocardiogram in Healthy Adults: A Comparison Study with Standard Electrocardiogram
Cardiol Res Pract. 2021 Feb 11;2021:6653061. doi: 10.1155/2021/6653061. eCollection 2021.ABSTRACTBACKGROUND: The standard electrocardiogram (ECG) is commonly performed in the supine posture. It may be difficult to report ECG in a supine posture for those who are unable to adopt the supine posture because of certain circumstances such as acute respiratory distress syndrome-patients who are placed in a prone position for long periods to improve oxygenation. Few data are available on the impact of the prone position on the ECG recording with electrodes on the posterior chest. Examining and analyzing the type and extent of cha...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Yunis Daralammouri Murad Azamtta Hamza Hamayel Amro Adas Osama Sawalmeh Yahia Ismail Saed H Zyoud Source Type: research

Trends in Stroke Prevention between 2014 and 2018 in Hospitalized Atrial Fibrillation Patients
Cardiol Res Pract. 2021 Feb 8;2021:6657776. doi: 10.1155/2021/6657776. eCollection 2021.ABSTRACTIn recent years, significant changes in stroke prophylaxis in patients with atrial fibrillation (AF) have been observed. Non-vitamin K antagonist oral anticoagulants (NOACs) are more commonly used in the prevention of thromboembolic complications in patients with AF. The aim of the study was to evaluate recommended stroke prophylaxis in patients with AF and to identify predictors of using NOACs in patients treated with anticoagulant therapy. The present study was a retrospective, observational, single-center study which included...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: B Bielecka I Gorczyca O Jelonek B Wo żakowska-Kapłon Source Type: research

Atrial Cardiomyopathy and Atrial Fibrillation in Cancer
Cardiol Res Pract. 2021 Feb 10;2021:6685953. doi: 10.1155/2021/6685953. eCollection 2021.ABSTRACTThe number of patients with oncologic and cardiologic comorbidities is increasing. A growing number of evidence shows an inextricable link between cancer, atrial fibrillation, and atrial cardiomyopathy. Cancer itself and resultant inflammation, anticancer treatment, and other comorbidities lead to atrial remodeling and fibrosis, which increases the tendency to develop atrial cardiomyopathy and atrial fibrillation. The scarcity of current literature and ambiguous results make its relationship difficult to fully understand. In th...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Mengdi Ren Yu Yao Xin Yue Yuye Ning Yan Yang Source Type: research

Clinical Phenotypes and Age-Related Differences in Presentation, Treatment, and Outcome of Heart Failure with Preserved Ejection Fraction: A Vietnamese Multicenter Research
Cardiol Res Pract. 2021 Jan 15;2021:4587678. doi: 10.1155/2021/4587678. eCollection 2021.ABSTRACTBACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a rising health problem with heterogeneous presentation and no evidence-based treatment. While Southeast Asia reported the highest mortality and morbidity among Asian population, little is known about the Vietnamese population, including patient characteristics, prescribing pattern and mortality rate.METHODS: We conducted an observational study on 477 patients diagnosed with HFpEF from seven hospitals in Southern Vietnam from January 2019 to December 2019.RES...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Ngoc-Thanh-Van Nguyen Diep Tuan Tran Pham Le An Sy Van Hoang Hoai-An Nguyen Hoa Ngoc Chau Source Type: research

Corrigendum to "Comparison of the CAMI-NSTEMI and GRACE Risk Model for Predicting In-Hospital Mortality in Chinese Non-ST-Segment Elevation Myocardial Infarction Patients"
Cardiol Res Pract. 2021 Feb 10;2021:5137403. doi: 10.1155/2021/5137403. eCollection 2021.ABSTRACT[This corrects the article DOI: 10.1155/2020/2469281.].PMID:33628488 | PMC:PMC7896849 | DOI:10.1155/2021/5137403 (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Peng Wang Hongliang Cong Ying Zhang Yujie Liu Source Type: research

Association between Serum Adiponectin and Atrial Fibrillation: A Case-Control Study Stratified by Age and Gender
Cardiol Res Pract. 2021 Feb 10;2021:6633948. doi: 10.1155/2021/6633948. eCollection 2021.ABSTRACTBACKGROUND: Circulating adiponectin has been suggested to be associated with atrial fibrillation (AF). However, whether the association differs by age and gender remains unknown. We performed a case-control study to evaluate the above association.METHODS: AF patients who underwent 24-hour long-range 12-channel electrocardiogram examination at our center were included in this study, and people with normal sinus rhythm (NSR) were included as controls. All participants underwent echocardiography and heart rate variability tests. B...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Tongjian Zhu Zhuo Wang Songyun Wang Wei Hu Hui Chen Jing Xie Meng Wang Kezhong Ma Hong Jiang Source Type: research

Impact of Prone Position on 12-Lead Electrocardiogram in Healthy Adults: A Comparison Study with Standard Electrocardiogram
Cardiol Res Pract. 2021 Feb 11;2021:6653061. doi: 10.1155/2021/6653061. eCollection 2021.ABSTRACTBACKGROUND: The standard electrocardiogram (ECG) is commonly performed in the supine posture. It may be difficult to report ECG in a supine posture for those who are unable to adopt the supine posture because of certain circumstances such as acute respiratory distress syndrome-patients who are placed in a prone position for long periods to improve oxygenation. Few data are available on the impact of the prone position on the ECG recording with electrodes on the posterior chest. Examining and analyzing the type and extent of cha...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Yunis Daralammouri Murad Azamtta Hamza Hamayel Amro Adas Osama Sawalmeh Yahia Ismail Saed H Zyoud Source Type: research

Trends in Stroke Prevention between 2014 and 2018 in Hospitalized Atrial Fibrillation Patients
Cardiol Res Pract. 2021 Feb 8;2021:6657776. doi: 10.1155/2021/6657776. eCollection 2021.ABSTRACTIn recent years, significant changes in stroke prophylaxis in patients with atrial fibrillation (AF) have been observed. Non-vitamin K antagonist oral anticoagulants (NOACs) are more commonly used in the prevention of thromboembolic complications in patients with AF. The aim of the study was to evaluate recommended stroke prophylaxis in patients with AF and to identify predictors of using NOACs in patients treated with anticoagulant therapy. The present study was a retrospective, observational, single-center study which included...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: B Bielecka I Gorczyca O Jelonek B Wo żakowska-Kapłon Source Type: research

Atrial Cardiomyopathy and Atrial Fibrillation in Cancer
Cardiol Res Pract. 2021 Feb 10;2021:6685953. doi: 10.1155/2021/6685953. eCollection 2021.ABSTRACTThe number of patients with oncologic and cardiologic comorbidities is increasing. A growing number of evidence shows an inextricable link between cancer, atrial fibrillation, and atrial cardiomyopathy. Cancer itself and resultant inflammation, anticancer treatment, and other comorbidities lead to atrial remodeling and fibrosis, which increases the tendency to develop atrial cardiomyopathy and atrial fibrillation. The scarcity of current literature and ambiguous results make its relationship difficult to fully understand. In th...
Source: Cardiology Research and Practice - February 25, 2021 Category: Cardiology Authors: Mengdi Ren Yu Yao Xin Yue Yuye Ning Yan Yang Source Type: research

Effects and Mechanisms of Cutting Upper Thoracic Sympathetic Trunk on Ventricular Rate in Ambulatory Canines with Persistent Atrial Fibrillation
Cardiol Res Pract. 2021 Feb 2;2021:8869264. doi: 10.1155/2021/8869264. eCollection 2021.ABSTRACTOBJECTIVE: The purpose is to observe the effects and neural mechanism of cutting upper thoracic sympathetic trunk (TST) on the ventricular rate (VR) during persistent atrial fibrillation (AF).METHODS: Twelve beagle dogs were halving to the control group and experimental group, 6 dogs for each group. Both groups were performed with left atrial rapid pacing (600 beats/min) to induce sustained AF. The experimental group underwent cutting upper TST after a sustained AF model was established, while the control group received thoracot...
Source: Cardiology Research and Practice - February 24, 2021 Category: Cardiology Authors: Jie Cai Min Tang Hao Liu Shiao Ding Rongxin Lu Wei Wang Nan Ma Ju Mei Zhaolei Jiang Source Type: research

Effects and Mechanisms of Cutting Upper Thoracic Sympathetic Trunk on Ventricular Rate in Ambulatory Canines with Persistent Atrial Fibrillation
Cardiol Res Pract. 2021 Feb 2;2021:8869264. doi: 10.1155/2021/8869264. eCollection 2021.ABSTRACTOBJECTIVE: The purpose is to observe the effects and neural mechanism of cutting upper thoracic sympathetic trunk (TST) on the ventricular rate (VR) during persistent atrial fibrillation (AF).METHODS: Twelve beagle dogs were halving to the control group and experimental group, 6 dogs for each group. Both groups were performed with left atrial rapid pacing (600 beats/min) to induce sustained AF. The experimental group underwent cutting upper TST after a sustained AF model was established, while the control group received thoracot...
Source: Cardiology Research and Practice - February 24, 2021 Category: Cardiology Authors: Jie Cai Min Tang Hao Liu Shiao Ding Rongxin Lu Wei Wang Nan Ma Ju Mei Zhaolei Jiang Source Type: research

Echocardiographic Features of Cardiomyopathy in Emery-Dreifuss Muscular Dystrophy
CONCLUSIONS: A significant number of EDMD patients present LV dilatation and different degrees of systolic dysfunction. Dilatation of the atria dominates over ventricle dilatation. We did not present any significant differences between EDMD1 and EDMD2 in terms of the morphology and the function of the heart.PMID:33614169 | PMC:PMC7878080 | DOI:10.1155/2021/8812044 (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - February 22, 2021 Category: Cardiology Authors: Micha ł Marchel Agnieszka Madej-Pilarczyk Agata Tymi ńska Roman Steckiewicz Janusz Kochanowski Julia Wysi ńska Ewa Ostrowska Pawe ł Balsam Marcin Grabowski Grzegorz Opolski Source Type: research

Echocardiographic Features of Cardiomyopathy in Emery-Dreifuss Muscular Dystrophy
CONCLUSIONS: A significant number of EDMD patients present LV dilatation and different degrees of systolic dysfunction. Dilatation of the atria dominates over ventricle dilatation. We did not present any significant differences between EDMD1 and EDMD2 in terms of the morphology and the function of the heart.PMID:33614169 | PMC:PMC7878080 | DOI:10.1155/2021/8812044 (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - February 22, 2021 Category: Cardiology Authors: Micha ł Marchel Agnieszka Madej-Pilarczyk Agata Tymi ńska Roman Steckiewicz Janusz Kochanowski Julia Wysi ńska Ewa Ostrowska Pawe ł Balsam Marcin Grabowski Grzegorz Opolski Source Type: research

Assessment of Concentrations of Heavy Metals in Postmyocardial Infarction Patients and Patients Free from Cardiovascular Event.
This study aimed to assess the concentration of some heavy metals (copper (Cu), zinc (Zn), manganese (Mn), cobalt (Co), and iron (Fe)) in the blood serum of postmyocardial infarction (post-MI) patients and patients free from myocardial infarction (MI) as well as estimate the relationship between the occurrence of MI and increased concentration of heavy metals. The concentration of heavy metals (Cu, Zn, Mn, Co, and Fe) was assessed using the inductively coupled plasma mass spectrometry technique in a group of 146 respondents divided into two groups: post-MI group (study group (SG), n = 74) and group without ca...
Source: Cardiology Research and Practice - February 21, 2021 Category: Cardiology Authors: Nowicki GJ, Ślusarska B, Prystupa A, Blicharska E, Adamczuk A, Czernecki T, Jankowski KJ Tags: Cardiol Res Pract Source Type: research

The Protective Effect of Cx43 Protein-Mediated Phosphocreatine on Myocardial Ischemia/Reperfusion Injury.
Conclusions: Phosphocreatine can improve the electrocardiogram and restore histologic changes in ischemic myocardium and coronary blood flow. The postulated mechanism is by inhibiting the generation of free oxygen radicals and restoring the expression of Cx43 protein. PMID: 33552599 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - February 9, 2021 Category: Cardiology Authors: Wang CX, Guo JJ, Di AJ, Zhu Y, Han WM, Cheng AR, Li C, Si RC, Lan TS, Zhang R, Liu HL, Yan GL Tags: Cardiol Res Pract Source Type: research

The Effect of Accessory Pathway Location on Cardiac Function in Adult Patients with Wolff-Parkinson-White Syndrome.
Conclusions: Anterograde conduction with a septal or right free wall accessory pathway may cause left ventricular dyssynchrony and impair left ventricular function. Intraventricular left ventricular dyssynchrony seems to be responsible for the pathogenesis of left ventricular dysfunction. Radiofrequency catheter ablation results in decreased NT-proBNP levels, normalized QRS duration, mechanical resynchronization, and improved left ventricular function. PMID: 33489357 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - January 27, 2021 Category: Cardiology Authors: Zhang Y, Xin M, Liu T, Song S, Wang W, Li J, Xu B, Hou X, Dong B Tags: Cardiol Res Pract Source Type: research

Metabonomics Analysis of Myocardial Metabolic Dysfunction in Patients with Cardiac Natriuretic Peptide Resistance.
Abstract Brain natriuretic peptide (BNP) is an important biological marker and regulator of cardiac function. BNP resistance is characterized by high concentrations of less functionally effective BNP and common in heart failure (HF) patients. However, the roles and consequences of BNP resistance remain poorly understood. Investigate the effects of cardiac BNP resistance and identify potential metabolic biomarkers for screening and diagnosis. Thirty patients and thirty healthy subjects were enrolled in this study. Cardiac functions were evaluated by echocardiography. The plasma levels of cyclic guanosine monophosph...
Source: Cardiology Research and Practice - December 31, 2020 Category: Cardiology Authors: Chang P, Lei S, Zhang X, Zhang J, Wang X, Wu J, Wang J, Geng J, Chen B, Yu J Tags: Cardiol Res Pract Source Type: research

Electrocardiographic Characteristics of Breast Cancer Patients Treated with Chemotherapy.
Abstract Introduction: Patients receiving chemotherapy for breast cancer may be at risk of developing cardiac dysfunction and electrophysiological abnormalities. The aim of this study is to evaluate alterations in electrocardiographic (ECG) parameters in breast cancer patients receiving chemotherapy. Materials and Methods: This was a prospective single-center cohort study conducted in the Fourth Hospital of Hebei Medical University, China. Participants with breast cancer referred for chemotherapy from May 1, 2019, to October 1, 2019, were invited to participate in the study. Standard 12-lead ECG and echocardi...
Source: Cardiology Research and Practice - December 31, 2020 Category: Cardiology Authors: Liang X, Wang Y, Yin X, Gong X, Pan S, Chen Z, Geng X Tags: Cardiol Res Pract Source Type: research

Characteristics and Surgical Results of Patients with Hypertrophic Obstructive Cardiomyopathy without Intrinsic Mitral Valve Diseases Undergoing Mitral Subvalvular Procedures during Myectomy.
Abstract Background: Mitral subvalvular procedures have acquired a major role during hypertrophic obstructive cardiomyopathy (HOCM) surgery. However, few studies have focused on characterizing the clinical feature of HOCM patients without intrinsic mitral valve (MV) diseases undergoing mitral subvalvular procedures in addition to myectomy. Additionally, scant data about the results of mitral subvalvular procedures during HOCM surgery are available. This single-center study aims to characterize the clinical feature and surgical results of HOCM patients without intrinsic MV diseases undergoing mitral subvalvular pro...
Source: Cardiology Research and Practice - December 31, 2020 Category: Cardiology Authors: Ji Q, Wang Y, Yang Y, Xia L, Ding W, Song K, Wang C Tags: Cardiol Res Pract Source Type: research

The Effect of the Teach-Back Method on Knowledge, Performance, Readmission, and Quality of Life in Heart Failure Patients.
Conclusion: Teach-back education improved patients' knowledge and performance, readmission frequency, and quality of life. PMID: 33299604 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - December 13, 2020 Category: Cardiology Authors: Rahmani A, Vahedian-Azimi A, Sirati-Nir M, Norouzadeh R, Rozdar H, Sahebkar A Tags: Cardiol Res Pract Source Type: research

Distinct Features of Gut Microbiota in High-Altitude Tibetan and Middle-Altitude Han Hypertensive Patients.
Abstract Indigenous animals show unique gut microbiota (GM) in the Tibetan plateau. However, it is unknown whether the hypertensive indigenous people in plateau also have the distinct gut bacteria, different from those living in plains. We sequenced the V3-V4 region of the gut bacteria 16S ribosomal RNA (rRNA) gene of feces samples among hypertensive patients (HPs) and healthy individuals (HIs) from 3 distinct altitudes: Tibetans from high altitude (3600-4500 m, n = 38 and 34), Hans from middle altitude (2260 m, n = 49 and 35), and Hans from low altitude (13 m, n&th...
Source: Cardiology Research and Practice - December 11, 2020 Category: Cardiology Authors: Zhu LL, Ma ZJ, Ren M, Wei YM, Liao YH, Shen YL, Fan SM, Li L, Wu QX, Gao ZS, Song JF, Ma YL Tags: Cardiol Res Pract Source Type: research

Alterations in the Properties of Red Blood Cells in Men with Coronary Artery Diseases after Comprehensive Cardiac Rehabilitation.
Conclusion: CCR in men with CAD after cardiac intervention is connected with decreased membrane fluidity and decreased membrane protein mobility, which indicates that reduction of oxidative changes in these components occurs. PMID: 33294220 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - December 11, 2020 Category: Cardiology Authors: Gwozdzinski K, Pieniazek A, Bernasinska-Slomczewska J, Brzeszczynska J, Irzmanski R, Jegier A Tags: Cardiol Res Pract Source Type: research

Synthesis and Appraisal of Natural Drug-Polymer-Based Matrices Relevant to the Application of Drug-Eluting Coronary Stent Coatings.
Abstract Cardiovascular diseases are becoming a leading cause of death in the world, and attention is being paid to develop natural drug-based treatment to cure heart diseases. Curcumin, ginger, and magnolol are pharmaceutically active in many ways, having properties including anticoagulation, antiproliferation, anti-inflammatory, and antioxidant, and may be used to synthesis coatings for drug-eluting stents to treat cardiovascular diseases. In the present investigation, a degradable polymer with varying molecular weights was used as a drug carrier to control the degradation of polymer; three different natural dru...
Source: Cardiology Research and Practice - December 8, 2020 Category: Cardiology Authors: Ghafoor B, Ali MN, Riaz Z Tags: Cardiol Res Pract Source Type: research

Circulating Soluble ST2 Predicts All-Cause Mortality in Severe Heart Failure Patients with an Implantable Cardioverter Defibrillator.
Conclusions: sST2 level was associated with risk of all-cause mortality, and a threshold of 43.43 ng/ml showed good distinguishing performance to predict all-cause mortality in patients with severe heart failure, recommended for ICD implantation. Patients with sST2 levels more than 43.42671 ng/ml even after ICD implantation should therefore be monitored carefully. PMID: 33282418 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - December 8, 2020 Category: Cardiology Authors: Hou ZW, Yu HB, Liang YC, Gao Y, Xu GQ, Wu M, Mei Z, Wang ZL, Li ZG, Li YY, Song HX, Li JY, Han YL Tags: Cardiol Res Pract Source Type: research

The Short QTc Is a Marker for the Development of Atrial Flutter and Atrial Fibrillation.
The objective was to identify cases with short QT and their consequences. Our hospital ECG database was screened for cases with a QTc based on the Bazett formula (QTcBZT) of less than 340 ms. The QTc was recalculated using the spline (QTcRBK) formula, which more accurately adjusts for the heart rate and identifies cases based on percentile distribution of the QT interval. The exclusion criteria were presence of bundle branch block, arrhythmias, or electronic pacemakers. An age- and sex-matched cohort was obtained from individuals with normal QT intervals with the same exclusion criteria. There were 28 cases with a s...
Source: Cardiology Research and Practice - November 24, 2020 Category: Cardiology Authors: Rabkin SW, Tang JKK Tags: Cardiol Res Pract Source Type: research

Bioinformatics Analysis Reveals Diagnostic Markers and Vital Pathways Involved in Acute Coronary Syndrome.
Conclusion: This study suggests that three genes (VEGFA, SPP1, and VCAM1) were involved in the molecular mechanisms of ACS pathogenesis and could serve as biomarkers of disease progression. PMID: 33224526 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - November 24, 2020 Category: Cardiology Authors: Li M, Ren C, Wu C, Li X, Li X, Mao W Tags: Cardiol Res Pract Source Type: research

Managing Nonagenarians with Acute Myocardial Infarction: Invasive versus Conservative Treatment.
Abstract Background: Limited data are available to support an invasive treatment strategy in nonagenarians with acute myocardial infarction (AMI). We aimed to investigate whether percutaneous coronary intervention (PCI) is beneficial in this frail population. Methods: We retrospectively analyzed 41 nonagenarians with AMI (both ST-segment-elevation and non-ST-segment-elevation MI) between 2006 and 2015 in a single center. We assessed 30-day and one-year mortality rates according to the treatment strategy. Results: Among study subjects, 24 (59%) were treated with PCI (PCI group) and 17 (41%) were treated w...
Source: Cardiology Research and Practice - November 24, 2020 Category: Cardiology Authors: Lee J, Seo KW, Park JS, Yang HM, Lim HS, Choi BJ, Choi SY, Yoon MH, Hwang GS, Tahk SJ, Shin JH Tags: Cardiol Res Pract Source Type: research

Metabolic Modulation and Potential Biomarkers of the Prognosis Identification for Severe Aortic Stenosis after TAVR by a Metabolomics Study.
Conclusion: This is the first study to reveal systemic and cardiac metabolites changed significantly in patients with AS after TAVR. Some altered metabolites involved in the arginine and proline metabolism pathway in the peripheral vein could predict left ventricle regression, which merited further study. PMID: 33204525 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - November 20, 2020 Category: Cardiology Authors: Liao Y, Liu C, Xiong T, Zhao M, Zheng W, Feng Y, Li Y, Ou Y, Zhao Z, Peng Y, Wei J, Li Q, Meng W, Liu X, Chen M Tags: Cardiol Res Pract Source Type: research

Rejuvenated Circulating Endothelial Progenitor Cells and Nitric Oxide in Premenopausal Women with Hyperhomocysteinemia.
Abstract Hyperhomocysteinemia (HHcy) induced endothelial dysfunction is associated with disturbance in circulating endothelial progenitor cells (EPCs). Nevertheless, whether this unfavorable effect of HHcy on circulating EPCs also exists in premenopausal women is still unknown. Therefore, this leaves an area for the investigation of the difference on the number and activity of circulating EPCs in premenopausal women with hyperhomocysteinemia and its underlying mechanism. The number of circulating EPCs was measured by fluorescence-activated cell sorter analysis, as well as DiI-acLDL and lectin fluorescent staining....
Source: Cardiology Research and Practice - November 20, 2020 Category: Cardiology Authors: Peng L, Gu Q, Huang Z, Zeng L, Chu C, Yang X Tags: Cardiol Res Pract Source Type: research

Systemic Lupus Erythematosus, Its Impact on Selected Cardiovascular Risk Factors, and Correlation with Duration of Illness: A Pilot Study.
Conclusions. Patients with SLE are at greater risk of developing cardiovascular diseases as the illness progresses. The activity of the disease according to the SLEDAI-2K scale may have an impact on the LVEF values which was significantly decreased in the group with active disease, but further thorough investigation is required to fully evaluate the impact of individual components of the disease and its treatment on the CVD development and mortality. PMID: 33204527 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - November 20, 2020 Category: Cardiology Authors: Przywara-Chowaniec B, Blachut D, Harpula J, Bereś M, Nowak A, Nowalany-Kozielska E Tags: Cardiol Res Pract Source Type: research

Prognostic Value of the Residual SYNTAX Score on In-Hospital and Follow-Up Clinical Outcomes in ST Elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Interventions.
Abstract Aims: We investigated the prognostic significance of residual SYNTAX score (RSS) in patients undergoing PCI due to STEMI and relationship between RSS and in-hospital and long-term ischemic cardiac events. Methods: Between June 2015 and December 2018, 538 patients who underwent primary PCI were evaluated for in-hospital events and 478 patients were evaluated for clinical events during follow-up. Primary and secondary endpoints for both in-hospital and follow-up periods were cardiac death and major adverse cardiac events (MACE). Results: 538 patients were included the study. RSS values of 131 pati...
Source: Cardiology Research and Practice - November 14, 2020 Category: Cardiology Authors: Altekin RE, Kilinc AY, Onac M, Cicekcibasi O Tags: Cardiol Res Pract Source Type: research

In-Stent Restenosis and a Drug-Coated Balloon: Insights from a Clinical Therapeutic Strategy on Coronary Artery Diseases.
Abstract Coronary heart disease is a major cause of death and disability in developed countries. Stent implantation has become an efficacious treatment for a culprit lesion vessel of the coronary artery. However, 10%-20% restenosis is still an important complication that restricts the clinical safety and efficacy of drug-eluting stents. In-stent restenosis may lead to the recurrence of major cardiovascular adverse events, including angina pectoris, acute myocardial infarction, and even sudden cardiac death. These events are currently serious problems that occur after coronary stent implantation. Clinical physician...
Source: Cardiology Research and Practice - November 11, 2020 Category: Cardiology Authors: Zhang DM, Chen S Tags: Cardiol Res Pract Source Type: research

Out-of-Hospital Cardiac Arrest due to Drowning in North America: Comparison of Patient Characteristics between Survival and Mortality Groups.
This study aims to compare patient characteristics between the survival group and mortality group of OHCA due to drowning. OHCA due to drowning cases were selected from the North America Termination of Resuscitation Association database between 2011 and 2015. The retrospective analysis of epidemiological characteristics and clinical features of all OHCA patients were performed. Of the 17,094 OHCA cases in the registry, 54 cases of OHCA due to drowning were included in this study. Among the 54 OHCAs due to drowning, 7 (13.0%) survived, while 47 (87.0%) died. Compared to the mortality group, the survival group had a higher b...
Source: Cardiology Research and Practice - November 7, 2020 Category: Cardiology Authors: Huang Z, Zhang W, Liao J, Liu Z, Xiong Y, Zhan H Tags: Cardiol Res Pract Source Type: research

Vitamin D (1,25-(OH)2D3) Improves Endothelial Progenitor Cells Function via Enhanced NO Secretion in Systemic Lupus Erythematosus.
Abstract It has been proven that vitamin D was decreased and function of circulating endothelial progenitor cells (EPCs) was injured in systemic lupus erythematosus (SLE) patients. However, the effect of vitamin D on the function of EPCs in vitro and its mechanism need further study. Therefore, we investigated whether vitamin D improved the function of EPCs in vitro. The peripheral blood mononuclear cells of the participants were isolated from SLE patients and control subjects and cultured to EPCs. After the EPCs were treated with vitamin D (1,25-(OH)2D3), we evaluated the number, migratory and proliferative activ...
Source: Cardiology Research and Practice - November 1, 2020 Category: Cardiology Authors: Huang Z, Liu L, Huang S, Li J, Feng S, Huang N, Ai Z, Long W, Jiang L Tags: Cardiol Res Pract Source Type: research

Postoperative New-Onset Atrial Fibrillation following Noncardiac Operations: Prevalence, Complication, and Long-Term MACE.
This study was intended to examine the incidence of POAF in noncardiothoracic surgeries performed under general anesthesia and its effects on the length of hospitalization stay, short-term and long-term morbidity, and mortality. Methodology. We conducted a retrospective observational descriptive study. The study population consists of patients hospitalized in surgical wards from January 2014 to December 2017. Surgery was defined as noncardiac or thoracic procedure conducted under general anesthesia. Results: A total of 24,125 general anesthesia operations were performed at 7 surgical wards. About two-fifth of the oper...
Source: Cardiology Research and Practice - November 1, 2020 Category: Cardiology Authors: Koren O, Hakim R, Israeli A, Rozner E, Turgeman Y Tags: Cardiol Res Pract Source Type: research

Value of Plasma NGAL and Creatinine on First Day of Admission in the Diagnosis of Cardiorenal Syndrome Type 1.
This study was aimed to evaluate the diagnostic efficacy of plasma NGAL in the diagnosis of CRS1. Methods: There were 139 patients with AHF or ADHF in the department of Cardiovascular Resuscitation and Interventional Cardiology at Ho Chi Minh City 115 People Hospital from September 2018 to March 2019. This was a prospective cohort study. Results: There were 48 cases (rate 34.5%) with CRS1, mean age was 66.12 ± 15.77 and men accounted for 50.4%. There were no significant differences of vital signs at admission, diagnosis, and EF-based heart failure between CRS1 and non-CRS1 groups. The urea, c...
Source: Cardiology Research and Practice - October 22, 2020 Category: Cardiology Authors: Phan Thai H, Hoang Bui B, Hoang Anh T, Huynh Van M Tags: Cardiol Res Pract Source Type: research

The Association of New-Onset Atrial Fibrillation and Risk of Cancer: A Systematic Review and Meta-Analysis.
This study aims to explore the relationship between NOAF and the risk of developing cancer through a meta-analysis with a large sample size. Methods: Electronic databases, such as PubMed and EMBASE, were searched for published relevant studies on NOAF patients diagnosed with cancer after and during follow-ups, including reported records of baseline information and the statistical result of morbidity. Two investigators independently reviewed the articles and extracted the data using uniform standards and definitions. The meta-analysis was conducted using the Cochrane Program Review Manager. Results: This meta-anal...
Source: Cardiology Research and Practice - October 21, 2020 Category: Cardiology Authors: Zhang M, Li LL, Zhao QQ, Peng XD, Wu K, Li X, Ruan YF, Bai R, Liu N, Ma CS Tags: Cardiol Res Pract Source Type: research

Impaired Mitophagy: A New Potential Mechanism of Human Chronic Atrial Fibrillation.
Abstract Mitophagy is an autophagic response and plays essential roles in survival, development, and homeostasis of cells. It has been reported that mitophagic dysfunction is involved in several cardiovascular diseases. However, the effect of mitophagy on atrial fibrillation (AF) is still unknown. Therefore, we investigated the exact role of mitophagy in human chronic AF. Western blot was used to detect the protein abundance. The mitochondrial morphology and structure were observed by transmission electron microscopy. Immunofluorescent stainings were performed to analyze colocalization of mitochondria with autopha...
Source: Cardiology Research and Practice - October 21, 2020 Category: Cardiology Authors: Zhou S, Dai W, Zhong G, Jiang Z Tags: Cardiol Res Pract Source Type: research

Effects of N-Acetylcysteine and N-Acetylcysteine Amide on Erythrocyte Deformability and Oxidative Stress in a Rat Model of Lower Extremity Ischemia-Reperfusion Injury.
Conclusion. The results of our study demonstrated the protective effects of NAC and NACA on erythrocyte deformability and oxidative damage in skeletal muscle in lower extremity ischemia-reperfusion. NAC and NACA exhibited similar protective effects on oxidative damage and erythrocyte deformability. PMID: 33062321 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - October 21, 2020 Category: Cardiology Authors: Erol G, Kartal H, Comu FM, Cetin E, Demirdas E, Sicim H, Unal CS, Gunay C, Oz BS, Bolcal C Tags: Cardiol Res Pract Source Type: research

Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention.
Conclusion: FBG was independently associated with MVO in nondiabetic STEMI patients. PMID: 33062322 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - October 21, 2020 Category: Cardiology Authors: Wu H, Li R, Wang K, Mu D, Chen JZ, Wei X, Bao X, Wei ZH, Xie J, Xu B Tags: Cardiol Res Pract Source Type: research

Matrix Metalloproteinase-2 Isoforms Differ within the Aortic Wall of Ascending Aortic Aneurysms Associated with Bicuspid Aortic Valve.
Abstract The pathogenesis of ascending thoracic aortic aneurysm (aTAA) is thought to differ between patients with bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV), and one of the causes is different hemodynamics. Influenced by hemodynamics, the tissue levels of proteins associated with aTAA might differ between aTAAs with BAV and TAV and between different localities within the aortic wall. We therefore analyzed aTAA tissue levels of MMP-2 (matrix metalloproteinase-2) isoforms (Pro-MMP-2, active MMP-2, and total MMP-2) and tissue levels of MMP-14, TIMP-2 (tissue inhibitor of metalloproteinase-2), MMP-9,...
Source: Cardiology Research and Practice - October 9, 2020 Category: Cardiology Authors: Schmitt R, Tscheuschler A, Laschinski P, Discher P, Fuchs J, Kari FA Tags: Cardiol Res Pract Source Type: research

Left Atrial Appendage Thrombus Formation Despite Continuous Non-Vitamin K Antagonist Oral Anticoagulant Therapy in Atrial Fibrillation Patients Undergoing Electrical Cardioversion or Catheter Ablation: A Comparison of Dabigatran and Rivaroxaban.
We examined the factors predisposing to LAAT in patients treated with the anticoagulants dabigatran and rivaroxaban. We retrospectively evaluated 1,256 AF patients from three centres who underwent TOE before electrical cardioversion (n = 611, 51.4%) or catheter ablation (n = 645, 48.6%) from January 2013 to December 2019 and had been on at least three weeks of continuous dabigatran (n = 603, 48%) or rivaroxaban (n = 653, 52%) therapy. Preprocedural TOE diagnosed LAAT in 51 patients (4.1%), including 30 patients (5%) treated with dabigatran and 21 patients (3.2%) treat...
Source: Cardiology Research and Practice - October 6, 2020 Category: Cardiology Authors: Gorczyca I, Chrapek M, Jelonek O, Michalska A, Kapłon-Cieślicka A, Uziębło-Życzkowska B, Budnik M, Gawałko M, Krzesiński P, Jurek A, Scisło P, Kochanowski J, Kiliszek M, Gielerak G, Filipiak KJ, Opolski G, Wożakowska-Kapłon B Tags: Cardiol Res Pract Source Type: research

Myocardial Scar on Surface ECG: Selvester Score, but Not Fragmentation, Predicts Response to CRT.
Conclusion: In HF patients with true-LBBB and LVEF ≤35% eligible for CRT, myocardial scar assessed by calculating the SSc on preimplant ECG is an independent predictor of nonresponse after multiple adjustments. Neither SSc nor fQRS is associated with overall and cardiac death, ventricular arrhythmias, or hospitalization for heart failure at a 24-month follow-up. PMID: 33014454 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - October 6, 2020 Category: Cardiology Authors: Nesti M, Perini AP, Bani R, Cartei S, Checchi L, Ricciardi G, Pieragnoli P, Michelotti F, Mascioli G, Cavarretta E, Sciarra L Tags: Cardiol Res Pract Source Type: research

The Effect of Sex Differences on Endothelial Function and Circulating Endothelial Progenitor Cells in Hypertriglyceridemia.
Abstract Background: Men have a higher risk and earlier onset of cardiovascular diseases compared with premenopausal women. Hypertriglyceridemia is an independent risk factor for the occurrence of ischemic heart disease. Endothelial dysfunction is related to the development of ischemic heart disease. Whether sex differences will affect the circulating endothelial progenitor cells (EPCs) and endothelial function in hypertriglyceridemia patients or not is not clear. Methods: Forty premenopausal women and forty age- and body mass index (BMI)-matched men without cardiovascular and metabolic disease were recruited...
Source: Cardiology Research and Practice - October 6, 2020 Category: Cardiology Authors: Ren Z, Guo J, Xiao X, Huang J, Li M, Cai R, Zeng H Tags: Cardiol Res Pract Source Type: research

Upregulation of MicroRNA-125b Leads to the Resistance to Inflammatory Injury in Endothelial Progenitor Cells.
Conclusions: miR-125b protects EPCs against TNF-α-induced inflammation and cell apoptosis by attenuating the activation of NF-κB pathway and consequently improves the cardiac function recovery and EPC-mediated neovascularization in the ischemic hearts. PMID: 33005452 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - October 3, 2020 Category: Cardiology Authors: Yang K, Liu X, Lin W, Zhang Y, Peng C Tags: Cardiol Res Pract Source Type: research

Correlation between the Serum Platelet-Derived Growth Factor, Angiopoietin-1, and Severity of Coronary Heart Disease.
Conclusion: The serum PDGF concentration in patients with acute coronary syndrome was significantly increased, especially in the local coronary artery. The serum Ang-1 in the coronary artery was significantly increased in patients with acute myocardial infarction and was related to the degree of coronary artery stenosis. Coronary sinus PDGF and Ang-1 levels can reflect the severity of lesions in patients with acute coronary syndrome. PMID: 32963822 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - September 25, 2020 Category: Cardiology Authors: Pang S, Tao Z, Min X, Zhou C, Pan D, Cao Z, Wang X Tags: Cardiol Res Pract Source Type: research

Echocardiography in Confirmed and Highly Suspected Symptomatic COVID-19 Patients and Its Impact on Treatment Change.
Conclusions: Echocardiography may be useful for the management of selected COVID-19 patients, especially those with elevated D-Dimer and Troponin levels, in up to 16% of patients. PMID: 32963823 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - September 25, 2020 Category: Cardiology Authors: Benyounes N, Van Der Vynckt C, Tibi S, Iglesias A, Salomon L, Gout O, Tibi T Tags: Cardiol Res Pract Source Type: research