Serum Concentrations of Osteogenesis/Osteolysis-Related Factors and Micro-RNA Expression in ST-Elevation Myocardial Infarction.
Conclusions: In STEMI patients, serum concentrations of osteogenesis/osteolysis factors, as well as miR-24-1 and miR-6802 expression, do not change significantly within the 3-month follow-up and are not correlated with LV remodeling and function. PMID: 31275638 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - July 7, 2019 Category: Cardiology Authors: Jadczyk T, Francuz T, Garczorz W, Kimsa-Furdzik M, Dutka M, Gaik E, Gruszczynska K, Syzdol M, Wanha W, Kurzelowski R, Fluder J, Starek Z, Wojakowski W Tags: Cardiol Res Pract Source Type: research

Effects of Minimal Extracorporeal Circulation on the Systemic Inflammatory Response and the Need for Transfusion after Coronary Bypass Grafting Surgery.
Conclusion: Our results show that MiECT seems to be more advantageous in terms of priming volume, perioperative hematocrit levels, need for blood and blood product transfusion, and mediastinal drainage with respect to the conventional approach after coronary artery bypass grafting. PMID: 31275639 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - July 7, 2019 Category: Cardiology Authors: Elçi ME, Kahraman A, Mutlu E, İspir CS Tags: Cardiol Res Pract Source Type: research

Cost-Effectiveness of Cardiac Rehabilitation in Patients with Coronary Artery Disease: A Meta-Analysis.
Abstract Background: Medical costs associated with cardiovascular disease are increasing considerably worldwide; therefore, an efficacious, cost-effective therapy which allows the effective use of medical resources is vital. There have been few economic evaluations of cardiac rehabilitation (CR), especially meta-analyses of medical cost versus patient outcome. Methods: The target population in this meta-analysis included convalescent and comprehensive CR patients with coronary artery disease (CAD), the status most commonly observed postmyocardial infarction (MI). Here, we evaluated medical costs, quality-adju...
Source: Cardiology Research and Practice - July 7, 2019 Category: Cardiology Authors: Takura T, Ebata-Kogure N, Goto Y, Kohzuki M, Nagayama M, Oikawa K, Koyama T, Itoh H Tags: Cardiol Res Pract Source Type: research

Novel Molecular Targets Participating in Myocardial Ischemia-Reperfusion Injury and Cardioprotection.
Abstract Worldwide morbidity and mortality from acute myocardial infarction (AMI) and related heart failure remain high. While effective early reperfusion of the criminal coronary artery after a confirmed AMI is the typical treatment at present, collateral myocardial ischemia-reperfusion injury (MIRI) and pertinent cardioprotection are still challenging to address and have inadequately understood mechanisms. Therefore, unveiling the related novel molecular targets and networks participating in triggering and resisting the pathobiology of MIRI is a promising and valuable frontier. The present study specifically foc...
Source: Cardiology Research and Practice - July 7, 2019 Category: Cardiology Authors: Liu NB, Wu M, Chen C, Fujino M, Huang JS, Zhu P, Li XK Tags: Cardiol Res Pract Source Type: research

A Review of the Epidemiological Evidence for Adducin Family Gene Polymorphisms and Hypertension.
Abstract Hypertension is one of the most common cardiovascular diseases that seriously endangers human health and has become a significant public health problem worldwide. In the vast majority of patients, the cause of hypertension is unknown, called essential hypertension (EH), accounting for more than 95% of total hypertension. Epidemiological and genetic studies of humans and animals provide strong evidence of a causal relationship between high salt intake and hypertension. Adducin is one of the important candidate genes for essential hypertension. Adducin is a heterodimeric or heterotetrameric protein that con...
Source: Cardiology Research and Practice - July 7, 2019 Category: Cardiology Authors: Zhang JR, Hu WN, Li CY Tags: Cardiol Res Pract Source Type: research

Anticoagulation Use prior to Common Dental Procedures: A Systematic Review.
Abstract Currently, the number of patients on oral anticoagulation is increasing. There is a paucity of data regarding maintaining oral anticoagulation (especially novel oral anticoagulants) around the time of specific dental procedures. A dentist has three options: either to stop anticoagulation, to continue it, or to bridge with heparin. A systematic review of 10 clinical trials was conducted to address this issue. It was found that continuing anticoagulation during dental procedures did not increase the risk of bleeding in most trials. Although none of the studies reported a thromboembolic event after interrupt...
Source: Cardiology Research and Practice - July 7, 2019 Category: Cardiology Authors: Chahine J, Khoudary MN, Nasr S Tags: Cardiol Res Pract Source Type: research

Predictors of Unfavorable Outcomes in Patients with Atrial Fibrillation and Concomitant Heart Failure with Different Ejection Fractions: RIF-CHF Register One-Year Follow-Up.
The objective of this study was to analyze how the features of the course of the diseases and management of HF + AF influence the clinical outcomes. Methods: The data of 1,003 patients from the first Russian register of patients with chronic heart failure and atrial fibrillation (RIF-CHF) were analyzed. The endpoints included hospitalization due to HF worsening, mortality, thromboembolic events, and hemorrhage. Predictors of unfavorable outcomes were analyzed separately for patients with HF and preserved ejection fraction (AF + HFpEF), midrange ejection fraction (AF + HFmrEF),...
Source: Cardiology Research and Practice - June 22, 2019 Category: Cardiology Authors: Zhirov I, Safronova N, Osmolovskaya Y, Alshevskaya A, Moskalev A, Tereshchenko S Tags: Cardiol Res Pract Source Type: research

Hypereosinophilic Syndrome, Cardiomyopathies, and Sudden Cardiac Death in Superinvasive Opisthorchiasis.
Abstract Cardiovascular pathology in patients with superinvasive opisthorchiasis is characterized by severe changes in haemodynamics and myocardial metabolism, impaired automatism, excitability, and conduction of the heart muscle. An analysis of 578 cases (medical and outpatient records and reports of pathoanatomical and forensic autopsies) recorded in healthcare facilities treating opisthorchiasis patients with a hyperendemic focus was carried out. We identified a set of cardiac changes in patients with hypereosinophilic syndrome associated with superinvasive opisthorchiasis infection, classified the pathological...
Source: Cardiology Research and Practice - June 20, 2019 Category: Cardiology Authors: Bychkov VG, Zolotukhin VM, Khadieva ED, Kulikova SV, Petrov IM, Berdinskih SG, Lazarev SD, Morozova LF, Morozov EN Tags: Cardiol Res Pract Source Type: research

Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon.
Abstract The coronary slow flow phenomenon (CSFP) is a poorly recognized clinical entity characterized by delayed distal vessel opacification in the absence of epicardial coronary stenosis and presently lack of specific data on the clinical profile and outcome. We investigated a cohort of 429 patients who fulfilled the criteria for CSFP to explore the clinical feature, outcome, and risk factor of prognosis. Two teams (clinical center and core lab) were blind to patient data for the assessment of coronary angiograph using corrected thrombolysis in myocardial infarction (TIMI) frame count (CTFC). The study cohort co...
Source: Cardiology Research and Practice - June 18, 2019 Category: Cardiology Authors: Zhu X, Shen H, Gao F, Wu S, Ma Q, Jia S, Zhao Z, Tong S, Zhang Z, Zhou Y Tags: Cardiol Res Pract Source Type: research

Additive Value of Biomarkers and Echocardiography to Stratify the Risk of Death in Heart Failure Patients with Reduced Ejection Fraction.
hio S Abstract Background: Risk stratification is a crucial issue in heart failure. Clinicians seek useful tools to tailor therapies according to patient risk. Methods: A prospective, observational, multicenter study on stable chronic heart failure outpatients with reduced left ventricular ejection fraction (HFrEF). Baseline demographics, blood, natriuretic peptides (NPs), high-sensitivity troponin I (hsTnI), and echocardiographic data, including the ratio between tricuspid annular plane excursion and systolic pulmonary artery pressure (TAPSE/PASP), were collected. Association with death for any cause was ana...
Source: Cardiology Research and Practice - June 15, 2019 Category: Cardiology Authors: Falletta C, Clemenza F, Klersy C, Agnese V, Bellavia D, Di Gesaro G, Minà C, Romano G, Temporelli PL, Dini FL, Rossi A, Raineri C, Turco A, Traversi E, Ghio S Tags: Cardiol Res Pract Source Type: research

Low-Dose Aspirin as Primary Prophylaxis for Cardiovascular Events in Rheumatoid Arthritis: An Italian Multicentre Retrospective Study.
Conclusion: The IR of CV events in our Italian multicentre cohort was lower than that reported in other European and non-European cohorts. Low-dose ASA may have a role in the primary prophylaxis of CV events in RA patients. PMID: 31192004 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - June 15, 2019 Category: Cardiology Authors: Iacono D, Fasano S, Pantano I, D'Abrosca V, Ruscitti P, Margiotta DPE, Navarini L, Maruotti N, Grembiale RD, Cantatore FP, Afeltra A, Giacomelli R, Valentini G Tags: Cardiol Res Pract Source Type: research

Prevention of Cardiovascular Disease: Screening for Magnesium Deficiency.
Abstract Magnesium is an essential mineral naturally present in the human body, where it acts as cofactor in several enzymatic reactions. Magnesium is a key cardiovascular regulator, which maintains electrical, metabolic, and vascular homeostasis. Moreover, magnesium participates in inflammation and oxidative processes. In fact, magnesium deficiency is involved in the pathophysiology of arterial hypertension, diabetes mellitus, dyslipidemia, metabolic syndrome, endothelial dysfunction, coronary artery disease, cardiac arrhythmias, and sudden cardiac death. In consideration of the great public-health impact of card...
Source: Cardiology Research and Practice - June 15, 2019 Category: Cardiology Authors: Severino P, Netti L, Mariani MV, Maraone A, D'Amato A, Scarpati R, Infusino F, Pucci M, Lavalle C, Maestrini V, Mancone M, Fedele F Tags: Cardiol Res Pract Source Type: research

Primary Mechanism Study of Panax notoginseng Flower (Herb) on Myocardial Infarction in Rats.
Conclusions: PN-F demonstrated a potential herb to treat rats with myocardial infarction through promoting angiogenesis and inhibition of apoptosis in the infarct area. PMID: 31192006 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - June 15, 2019 Category: Cardiology Authors: Zhou X, Li ZC, Chen PP, Xie RF Tags: Cardiol Res Pract Source Type: research

Effects of Cardiac Hypertrophy, Diabetes, Aging, and Pregnancy on the Cardioprotective Effects of Postconditioning in Male and Female Rats.
The objective of this study was to investigate the vulnerability of hearts with aging, LVH, diabetes, and pregnancy to ischemic insult and their response to pacing postconditioning- (PPC-) induced heart protection. Methods: Hearts isolated from aged, spontaneously hypertensive and diabetic male and female rats and hearts from pregnant female rats (n=8 per group) were subjected to coronary occlusion followed by reperfusion using a modified Langendorff system. Hemodynamics data were computed digitally, and cardiac damage was accessed by measurements of infarct size and cardiac enzyme release. Results: There were no...
Source: Cardiology Research and Practice - June 15, 2019 Category: Cardiology Authors: Babiker F, Al-Jarallah A, Al-Awadi M Tags: Cardiol Res Pract Source Type: research

Genetic Variants Are Not Rare in ICD Candidates with Dilated Cardiomyopathy: Time for Next-Generation Sequencing?
Conclusion: In patients with DCM and ICD, genetic variants could be identified in a significant proportion of patients in several genes, highlighting the potential role of genetics in DCM SCD risk stratification. PMID: 31179125 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - June 12, 2019 Category: Cardiology Authors: Sousa A, Canedo P, Campelo M, Moura B, Leite S, Baixia M, Belo A, Rocha-Gonçalves F, Machado JC, Silva-Cardoso J, Martins E, Fatima Investigators Tags: Cardiol Res Pract Source Type: research

Non-HDL-c/TC: A Novel Lipid-Related Marker in the Assessment of Severity of Coronary Artery Lesions and Cardiovascular Outcomes.
Abstract Background: Non-high-density lipoprotein cholesterol (non-HDL-c) predicts the severity of coronary artery lesions in patients not treated with statin. The association between non-HDL-c and severity of coronary artery lesions in patients treated with lipid-lowering therapy has been unknown. Hypothesis: We hypothesize a novel marker of non-HDL-c/TC predicts the severity of coronary artery lesions and clinical outcomes in 12 months in the patients treated with statin. Method: 473 subjects who met inclusion criteria were eligible for inclusion. Coronary artery angiography (CAG) was performed,...
Source: Cardiology Research and Practice - June 12, 2019 Category: Cardiology Authors: Huang A, Qi X, Wei L, Zhang M, Zhou S Tags: Cardiol Res Pract Source Type: research

Increased C-Reactive Protein in Brazilian Children: Association with Cardiometabolic Risk and Metabolic Syndrome Components (PASE Study).
The objective was to evaluate the high-sensitive CRP (hs-CRP) and its association with traditional and nontraditional cardiometabolic risk factors, as well as metabolic syndrome (MetS) components in Brazilian children. This is a cross-sectional representative study, with participants of the Schoolchildren Health Assessment Survey (PASE). Children from 8 to 9 years old (n=350) enrolled in public and private schools in the municipality of Viçosa, Minas Gerais, Brazil, were evaluated. Sociodemographic evaluation was performed through a semistructured questionnaire. Anthropometric, body composition, clinical, and...
Source: Cardiology Research and Practice - June 1, 2019 Category: Cardiology Authors: Suhett LG, Hermsdorff HHM, Rocha NP, Silva MA, Filgueiras MS, Milagres LC, Peluzio MDCG, de Novaes JF Tags: Cardiol Res Pract Source Type: research

Preoperative Low-Molecular-Weight Heparin Prophylaxis Associated with Increased Heparin Resistance Frequency in On-Pump Coronary Artery Bypass Graft Surgery.
Conclusion: Preoperative treatment with LMWH may cause intraoperative HR. Corrective and preventive arrangements with close follow-up should be performed in this group of patients. PMID: 31143477 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - June 1, 2019 Category: Cardiology Authors: Saydam O, Atay M, Serefli D, Doganci S, Kumabasar U, Yılmaz M, Dogan R, Demircin M Tags: Cardiol Res Pract Source Type: research

LncRNA-MIAT Increased in Patients with Coronary Atherosclerotic Heart Disease.
Conclusions: Serum lncRNA-MIAT in CAD patients was significantly increased, which may be a potential marker for diagnosis and prognosis of CAD. PMID: 31143478 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - June 1, 2019 Category: Cardiology Authors: Tan J, Liu S, Jiang Q, Yu T, Huang K Tags: Cardiol Res Pract Source Type: research

Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility.
Conclusions: SIRT1 single-nucleotide polymorphisms were associated with premature myocardial infarction, which affected the SIRT1 and endothelial nitric oxide synthase protein expression, irrespective of the underlying SIRT1 genotype. PMID: 31143479 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - June 1, 2019 Category: Cardiology Authors: Yamac AH, Uysal O, Ismailoglu Z, Ertürk M, Celikten M, Bacaksiz A, Kilic U Tags: Cardiol Res Pract Source Type: research

Association of Cancer and the Risk of Developing Atrial Fibrillation: A Systematic Review and Meta-Analysis.
Abstract Aims: Previous studies have demonstrated epidemiological evidence for an association between cancer and the development of new-onset atrial fibrillation (AF). However, these results have been conflicting. This systematic review and meta-analysis was conducted to examine the relationship between cancer and the risk of developing atrial fibrillation. Methods: PubMed and Web of Science were searched for publications examining the association between cancer and atrial fibrillation risk published until June 2017. Adjusted odds ratios (ORs) or hazard ratios (HRs) and 95% CI were extracted and pooled. ...
Source: Cardiology Research and Practice - May 22, 2019 Category: Cardiology Authors: Yuan M, Zhang Z, Tse G, Feng X, Korantzopoulos P, Letsas KP, Yan BP, Wu WKK, Zhang H, Li G, Liu T, Xia Y Tags: Cardiol Res Pract Source Type: research

Echocardiographic Findings in Patients with Atrial Septal Aneurysm: A Prospective Case-Control Study.
Abstract Background: Atrial septal aneurysm (ASA) is a congenital deformity of the interatrial septum with a prevalence of 1-2% in the adult population. Although ASA has been supposed to be an incidental finding in echocardiographic examination, its structural and clinical associations have gained an increasing interest. Aim: To investigate and compare the clinical features and echocardiographic parameters between ASA patients and age- and gender-matched control group patients. Methods: 410 patients with ASA were enrolled in the study, prospectively. After the exclusion of 33 patients, the remaining 377 ...
Source: Cardiology Research and Practice - May 9, 2019 Category: Cardiology Authors: Atak R, Ileri M, Ozturk S, Korkmaz A, Yetkin E Tags: Cardiol Res Pract Source Type: research

Resting Heart Rate and Long-Term Outcomes in Patients with Percutaneous Coronary Intervention: Results from a 10-Year Follow-Up of the CORFCHD-PCI Study.
Abstract Background: The relationship between heart rate in CAD patients who underwent percutaneous coronary intervention (PCI) and had long-term outcomes over up to 10 years of follow-up has not been investigated. Methods: All patients were from the CORFCHD-PCI, a retrospective cohort study that included a total of 6050 CAD patients who underwent PCI from January 2008 to December 2016. One patient was excluded due to a lack of heart rate data. Ultimately, 6049 patients were enrolled. The primary outcome was long-term mortality after PCI. Results: Patients were divided into 5 groups according to h...
Source: Cardiology Research and Practice - May 9, 2019 Category: Cardiology Authors: Zheng YY, Wu TT, Chen Y, Hou XG, Yang Y, Ma X, Ma YT, Zhang JY, Xie X Tags: Cardiol Res Pract Source Type: research

Incidental Findings Diagnosed during Preprocedural Evaluation of TAVR.
Conclusion: Preprocedural evaluation is one of the most important steps in TAVR. Computed tomography imaging provides extensive information, not only for procedure planning. Our findings emphasize that computed tomography has a crucial role for the preprocedural evaluation of TAVR candidates. PMID: 31061731 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - May 9, 2019 Category: Cardiology Authors: Sahiner L, Coteli C, Kivrak A, Sener YZ, Asil S, Hazirolan T, Kaya EB, Ozer N, Aytemir K Tags: Cardiol Res Pract Source Type: research

Biomarkers of Atrial Fibrillation: Which One Is a True Marker?
Abstract Atrial fibrillation (AF) is the most common sustained cardiac arrhythmias and associated with the risk of stroke and death. Continuous development of the diagnostic tool and prognostic stratification may lead to optimal management of AF. The use of biomarkers in the management of AF has been grown as an interesting topic. However, the AF biomarkers are not yet well established in the major guidelines. Among these biomarkers, a lot of data show troponin and brain natriuretic peptides are promising for the prediction of future events. The troponin elevation in AF patients may not necessarily be diagnosed as...
Source: Cardiology Research and Practice - May 9, 2019 Category: Cardiology Authors: Ardhianto P, Yuniadi Y Tags: Cardiol Res Pract Source Type: research

Effects of Ivabradine on Residual Myocardial Ischemia after PCI Evaluated by Stress Echocardiography.
Conclusions: Ivabradine seems to produce a significant improvement of ischemic threshold, chronotropic reserve, and diastolic function. PMID: 31061733 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - May 9, 2019 Category: Cardiology Authors: Calcagno S, Infusino F, Dettori O, Taccheri T, Bruno P, Maestrini V, Sardella G, Mancone M, Fedele F Tags: Cardiol Res Pract Source Type: research

Concordance between the Different Cardiovascular Risk Scores in People with Rheumatoid Arthritis and Psoriasis Arthritis.
Abstract Aim: To determine the cardiovascular risk and the concordance between the different scores in people with rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Methods: Observational descriptive study of prevalence. Performed in the Rheumatology Service and the Clinical Epidemiology and Biostatistics Unit of the University Hospital Complex of A Coruña (Spain). Patients diagnosed with RA or PsA, older than 18 years of age were included. Measurements: sociodemographic, anthropometric variables of the disease, comorbidity, cardiovascular risk, and therapeutic management. Results: 1...
Source: Cardiology Research and Practice - April 21, 2019 Category: Cardiology Authors: Gonzalez-Martin C, Grande Morais S, Pertega-Diaz S, Seoane-Pillado T, Balboa-Barreiro V, Veiga-Seijo R Tags: Cardiol Res Pract Source Type: research

Retracted: A Comprehensive Review on Metabolic Syndrome.
Abstract [This retracts the article DOI: 10.1155/2014/943162.]. PMID: 30993018 [PubMed - in process] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - April 19, 2019 Category: Cardiology Authors: Practice CRA Tags: Cardiol Res Pract Source Type: research

Coronary Atherosclerotic Plaque Vulnerability Rather than Stenosis Predisposes to Non-ST Elevation Acute Coronary Syndromes.
Conclusions: The vulnerability rather than the stenotic severity is the most important factor that predisposes to non-ST segment elevation acute coronary syndromes. The vulnerability is related to the lesion characteristics especially lipidic core and calcification while lesion fibrosis favours lesion stability. PMID: 30984422 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - April 16, 2019 Category: Cardiology Authors: Laimoud M, Faris F, Elghawaby H Tags: Cardiol Res Pract Source Type: research

Red Cell Distribution Width as a Novel Marker for Different Types of Atrial Fibrillation in Low and High Altitude.
Abstract Background: Increased red cell distribution width (RDW) can predict the incidence and mortality of cardiovascular diseases. However, there are limited data on the relationship between RDW and altitude and the subtype of atrial fibrillation (AF). We investigated the effects of altitude on RDW in patients with different types of AF. Methods: A total of 303 patients with nonvalvular AF were included. Of these, 156 lived in low altitude (77 paroxysmal AF, PAF; 79 persistent AF, PeAF) and 147 in high altitude (77 paroxysmal AF, PAF; 70 persistent AF, PeAF). In these groups, baseline characteristics, compl...
Source: Cardiology Research and Practice - April 16, 2019 Category: Cardiology Authors: Han K, Su X, Liu J, Yao F, Lu F Tags: Cardiol Res Pract Source Type: research

HDL Particle Size and Functionality Comparison between Patients with and without Confirmed Acute Myocardial Infarction.
This study was carried out to evaluate the structure (molecular and particle size) and functionality of high-density lipoprotein (HDL) shortly after AMI, in the presence of acute inflammatory response. Casuistic and Methods: A cross-sectional, observational study was conducted between January 2015 and August 2016, with a total convenient sample of 85 patients. The patients' data were segregated according to the Registry of Acute Myocardial Infarction (REAMI), with 45 confirmed AMI patients. The study groups consisted of patients from both sexes, older than 35 years, presented to the Hospital São Rafael (...
Source: Cardiology Research and Practice - April 6, 2019 Category: Cardiology Authors: de Miranda Teixeira R, Cruz de Sá N, Caires Dos Santos AP, Anjos E Silva VR, de Magalhães Cabral Albuquerque EC, Lemos Correia LC, Couto RD Tags: Cardiol Res Pract Source Type: research

Leukodepleted Packed Red Blood Cells Transfusion in Patients Undergoing Major Cardiovascular Surgical Procedure: Systematic Review and Meta-Analysis.
Conclusions: We found evidence that supports the routine use of leukodepletion in patients undergoing a major cardiovascular surgical procedure requiring PRBC transfusion to prevent death and infection. In the case of infection, the evidence should be considered sufficient and conclusive and hence indicated that further trials would not be required. PMID: 30931154 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - April 2, 2019 Category: Cardiology Authors: Simancas-Racines D, Arevalo-Rodriguez I, Urrutia G, Buitrago-Garcia D, Núñez-González S, Martínez-Zapata MJ, Madrid E, Bonfill X, Hidalgo-Ottolenghi R Tags: Cardiol Res Pract Source Type: research

Comparison of Echocardiographic and Electrocardiographic Mapping for Cardiac Resynchronisation Therapy Optimisation.
Abstract Study hypothesis: We sought to investigate the association between echocardiographic optimisation and ventricular activation time in cardiac resynchronisation therapy (CRT) patients, obtained through the use of electrocardiographic mapping (ECM). We hypothesised that echocardiographic optimisation of the pacing delay between the atrial and ventricular leads-atrioventricular delay (AVD)-and the delay between ventricular leads-interventricular pacing interval (VVD)-would correlate with reductions in ventricular activation time. Background: Optimisation of AVD and VVD may improve CRT patient outcome. Op...
Source: Cardiology Research and Practice - March 30, 2019 Category: Cardiology Authors: Pereira H, Jackson TA, Claridge S, Behar JM, Yao C, Sieniewicz B, Gould J, Porter B, Sidhu B, Gill J, Niederer S, Rinaldi CA Tags: Cardiol Res Pract Source Type: research

Triggers for Atrial Fibrillation: The Role of Anxiety.
Abstract Atrial fibrillation (AF) is the most widely recognized arrhythmia. Systemic arterial hypertension, diabetes, obesity, heart failure, and valvular heart diseases are major risk factors for the onset and progression of AF. Various studies have emphasized the augmented anxiety rate among AF patients due to the poor quality of life; however, little information is known about the possibility of triggering atrial fibrillation by anxiety. The present review sought to underline the possible pathophysiological association between AF and anxiety disorders and suggests that anxiety can be an independent risk factor ...
Source: Cardiology Research and Practice - March 26, 2019 Category: Cardiology Authors: Severino P, Mariani MV, Maraone A, Piro A, Ceccacci A, Tarsitani L, Maestrini V, Mancone M, Lavalle C, Pasquini M, Fedele F Tags: Cardiol Res Pract Source Type: research

Association of Autoantibodies against M2-Muscarinic Acetylcholine Receptor with Atrial Fibrosis in Atrial Fibrillation Patients.
Abstract Objectives: To investigate the association of serum autoantibodies against M2-muscarinic acetylcholine receptor (anti-M2-R) with atrial fibrosis in long-standing persistent atrial fibrillation (AF) patients. Methods: Twenty-four long-standing persistent AF patients, scheduled to undergo hybrid ablation surgery, were enrolled in the study. Twenty-six patients with sinus rhythm, scheduled to undergo coronary artery bypass grafting surgery, were enrolled into the non-AF group. We detected serum anti-M2-R levels. Left atrial appendages were subjected to histological and molecular biological assays. Patie...
Source: Cardiology Research and Practice - March 15, 2019 Category: Cardiology Authors: Ma G, Wu X, Zeng L, Jin J, Liu X, Zhang J, Zhang L Tags: Cardiol Res Pract Source Type: research

Timeout for Contrast: Using Physician Behavior Modification to Reduce Contrast in the Catheterization Laboratory.
Conclusion: A significant reduction in radiocontrast use across all operators and procedures after the introduction of a revised timeout procedure that was seen, which is a change that was sustained over a period of three years. With this straightforward intervention involving physician behavioral modification, patients were exposed to less of the nephrotoxic contrast and were consequently at a lower risk of developing dose-depended CIN and other associated complications. PMID: 30766733 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - February 17, 2019 Category: Cardiology Authors: Singh R, Zughaib M Tags: Cardiol Res Pract Source Type: research

Left Atrial Appendage Occlusion Guided Only by Transesophageal Echocardiography.
Conclusions: TEE-guided left atrial appendage occlusion is safe and reliable, simplifies the procedure, protects doctors and patients from radiation, and is gradually becoming the mainstream operation for left atrial appendage occlusion. This trial is registered with ChiCTR1800018387. PMID: 30719340 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - February 7, 2019 Category: Cardiology Authors: Zhao J, Li F, Zhang Y, Zhuang Z, Wang M, Fu L, Ni Y, Lu Z, Chen Z, Zhang C Tags: Cardiol Res Pract Source Type: research

Low-Dose Ibutilide Combined with Catheter Ablation of Persistent Atrial Fibrillation: Procedural Impact and Clinical Outcome.
Abstract Background: In patients with persistent atrial fibrillation (AF), the procedural and clinical outcomes of ablation combined with infusion of antiarrhythmic drug are unknown. Objectives: To determine the impact of low-dose ibutilide after circumferential pulmonary vein isolation (CPVI) and/or left atrial (LA) substrate modification on acute procedural and clinical outcome of persistent AF. Methods: In a prospective cohort of 135 consecutive patients with persistent AF, intravenous 0.25 mg ibutilide was administered 3 days before the procedure and intraprocedurally, if required, after CPVI ...
Source: Cardiology Research and Practice - February 7, 2019 Category: Cardiology Authors: Sun XR, Tian Y, Shah A, Yin XD, Shi L, Wang YJ, Liu XQ, Hocini M, Haissaguerre M, Yang XC, Liu XP Tags: Cardiol Res Pract Source Type: research

Serum Nickel and Titanium Levels after Transcatheter Closure of Atrial Septal Defects with Amplatzer Septal Occluder.
Discussion: This is the first study that evaluated both serum nickel and titanium release after implantation of the Amplatzer occluder. Our study shows that nickel is released from the device in the first few months after implantation. Therefore, in patients with nickel allergy, other devices may be considered. PMID: 30719342 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - February 7, 2019 Category: Cardiology Authors: Elkiran O, Karakurt C, Kocak G, Taskapan C Tags: Cardiol Res Pract Source Type: research

Therapeutic Targeting of the Proinflammatory IL-6-JAK/STAT Signalling Pathways Responsible for Vascular Restenosis in Type 2 Diabetes Mellitus.
Abstract Type 2 diabetes mellitus (T2DM) is increasing worldwide, and it is associated with increased risk of coronary artery disease (CAD). For T2DM patients, the main surgical intervention for CAD is autologous saphenous vein grafting. However, T2DM patients have increased risk of saphenous vein graft failure (SVGF). While the mechanisms underlying increased risk of vascular disease in T2DM are not fully understood, hyperglycaemia, insulin resistance, and hyperinsulinaemia have been shown to contribute to microvascular damage, whereas clinical trials have reported limited effects of intensive glycaemic control i...
Source: Cardiology Research and Practice - February 7, 2019 Category: Cardiology Authors: Moshapa FT, Riches-Suman K, Palmer TM Tags: Cardiol Res Pract Source Type: research

"Traditional" and "Healthy" Dietary Patterns Are Associated with Low Cardiometabolic Risk in Brazilian Subjects.
This study aimed at determining the dietary patterns and investigating their association with cardiometabolic risk markers in a brazilian population at risk. This transversal study was carried out with data of 265 patients (n = 123 M/172 W, age 42 ± 16 years) of the Cardiovascular Health Care Program-PROCARDIO-UFV, Brazil-who had their first appointment between 2012 and 2017. A 24-hour recall was applied. The dietary patterns were determined by Principal Component Analysis. Anthropometric, clinical-metabolic, sociodemographic, and lifestyle data were collected through medical record analysis. Five patt...
Source: Cardiology Research and Practice - December 26, 2018 Category: Cardiology Authors: Silveira BKS, de Novaes JF, Reis NA, Lourenço LP, Capobiango AHM, Vieira SA, Hermsdorff HHM Tags: Cardiol Res Pract Source Type: research

CardioMEMS in a Busy Cardiology Practice: Less than Optimal Implementation of a Valuable Tool to Reduce Heart Failure Readmissions.
Conclusion: Despite the benefits to patients and reducing healthcare expenditure, there has been a poor adaptation of this groundbreaking technology. Our study revealed that 79% of eligible heart failure patients did not receive the device. Therefore, efforts need to be undertaken to improve physician and patient education of the device to complement the current standard of care for congestive heart failure. PMID: 30524758 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - December 15, 2018 Category: Cardiology Authors: Singh R, Varjabedian L, Kaspar G, Zughaib M Tags: Cardiol Res Pract Source Type: research

Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis.
k P Abstract Background: Fast progression of the transaortic mean gradient (P mean) is relevant for clinical decision making of valve replacement in patients with moderate and severe aortic stenosis (AS) patients. However, there is currently little knowledge regarding the determinants affecting progression of transvalvular gradient in AS patients. Methods: This monocentric retrospective study included consecutive patients presenting with at least two transthoracic echocardiography examinations covering a time interval of one year or more between April 2006 and February 2016 and diagnosed as moderate or severe...
Source: Cardiology Research and Practice - December 12, 2018 Category: Cardiology Authors: Salinger T, Hu K, Liu D, Taleh S, Herrmann S, Oder D, Gensler D, Müntze J, Ertl G, Lorenz K, Frantz S, Weidemann F, Nordbeck P Tags: Cardiol Res Pract Source Type: research

A Pilot Study on Parameter Setting of VisiTag ™ Module during Pulmonary Vein Isolation.
Conclusion: A 3 mm distance limit for at least 20 s and FOT being a minimal force of 5 g with 50% stability time might be OPC for the VisiTag™ module. PMID: 30510796 [PubMed] (Source: Cardiology Research and Practice)
Source: Cardiology Research and Practice - December 6, 2018 Category: Cardiology Authors: Wang YC, Huang B, Li K, He PK, Chen ED, Xia YL, Jiang J, Sheng QH, Zhou J, Ding YS Tags: Cardiol Res Pract Source Type: research

Croatian National Data and Comparison with European Practice: Data from the Cardiac Resynchronization Therapy Survey II Multicenter Registry.
ola S Abstract Aims: The Cardiac Resynchronization Therapy (CRT) Survey II was conducted between October 2015 and December 2016 and included data from 11088 CRT implantations from 42 countries. The survey's aim was to report on current European CRT practice. The aim of this study was to compare the Croatian national CRT practice with the European data. Methods: Five centres from Croatia recruited consecutive patients, in a 15-month period, who underwent CRT implantation, primary or an upgrade. Data were collected prospectively by using online database. Results: A total of 115 patients were included in Cr...
Source: Cardiology Research and Practice - December 2, 2018 Category: Cardiology Authors: Brusich S, Zeljković I, Pavlovic N, Anić A, Jurišić Z, Židan D, Klasan M, Čubranić Z, Dickstein K, Linde C, Normand C, Manola S Tags: Cardiol Res Pract Source Type: research

The First Harmonic of Radial Pulse as an Early Predictor of Silent Coronary Artery Disease and Adverse Cardiac Events in Type 2 Diabetic Patients.
Abstract Background: It has been reported that harmonics of radial pulse is related to coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM). It is still unclear whether or not the first harmonics of the radial pulse spectrum is an early independent predictor of silent coronary artery disease (SCAD) and adverse cardiac events (ACE). Objectives: To measure the risk of SCAD in patients with T2DM and also to survey whether or not an increment of the first harmonic (C1) of the radial pulse increases ACE. Methods: 1968 asymptomatic individuals with T2DM underwent radial pulse wave mea...
Source: Cardiology Research and Practice - November 15, 2018 Category: Cardiology Authors: Chang CW, Liao KM, Chang YT, Wang SH, Chen YC, Wang GC Tags: Cardiol Res Pract Source Type: research

Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence.
Abstract As advances in medical technology arise and the availability of cancer treatment increases, an increased number of patients are receiving cancer treatment. Radiation therapy has evolved to become one of the cornerstones of treatment for various types of cancers. One of the long-term consequences of radiation therapy is radiation-induced coronary artery disease (RICAD). Although the pathophysiology of RICAD may be slightly different and more acute onset than the commonly seen "generic" coronary artery disease, it is common practice to treat RICAD in the same method as nonradiation-induced CAD. Th...
Source: Cardiology Research and Practice - November 11, 2018 Category: Cardiology Authors: DeZorzi C Tags: Cardiol Res Pract Source Type: research

Disparities in the Diagnosis of Hypertrophic Obstructive Cardiomyopathy: A Narrative Review of Current Literature.
Abstract Hypertrophic obstructive cardiomyopathy (HOCM) is a disorder of abnormal thickening of the myocardium that affects 0.2% of the population. HOCM is a frequently implicated cause of sudden cardiac death (SCD) in young athletes. In this manner, this condition has the capacity for tremendous emotional, social, financial, and medical burdens for families and communities across the country. Multiple factors including genetics and hormonal elements are believed to play a role in the development of this cardiomyopathy. HOCM is an autosomal dominant trait with variable expressivity. It is associated with several g...
Source: Cardiology Research and Practice - October 30, 2018 Category: Cardiology Authors: Burns J, Jean-Pierre P Tags: Cardiol Res Pract Source Type: research

Echo- and B-Type Natriuretic Peptide-Guided Follow-Up versus Symptom-Guided Follow-Up: Comparison of the Outcome in Ambulatory Heart Failure Patients.
ni FL Abstract Recent European Society of Cardiology and American Heart Association/American College of Cardiology Guidelines did not recommend biomarker-guided therapy in the management of heart failure (HF) patients. Combination of echo- and B-type natriuretic peptide (BNP) may be an alternative approach in guiding ambulatory HF management. Our aim was to determine whether a therapy guided by echo markers of left ventricular filling pressure (LVFP), lung ultrasound (LUS) assessment of B-lines, and BNP improves outcomes of HF patients. Consecutive outpatients with LV ejection fraction (EF) ≤ 50% ...
Source: Cardiology Research and Practice - October 28, 2018 Category: Cardiology Authors: Bajraktari G, Pugliese NR, D'Agostino A, Rosa GM, Ibrahimi P, Perçuku L, Miccoli M, Galeotti GG, Fabiani I, Pedrinelli R, Henein M, Dini FL Tags: Cardiol Res Pract Source Type: research

Prognostic Value of SYNTAX Score II in Patients with Acute Coronary Syndromes Referred for Invasive Management: A Subanalysis from the SPUM and COMFORTABLE AMI Cohorts.
Lüscher TF Abstract Aims: To assess the incremental prognostic value of SYNTAX score II (SxSII) as compared to anatomical SYNTAX Score (SxS) and GRACE risk score in patients with acute coronary syndromes who underwent percutaneous coronary intervention. Methods and results: SxSII and SxS were determined in 734 ACS patients. Patients were enrolled in the prospective Special Program University Medicine ACS and the COMFORTABLE AMI cohorts and later on stratified according to tertiles of SxSII (SxSIILow ≤21.5 (n=245), SxSIIMid 21.5-30.6 (n=245), and SxSIIHigh ≥30.6 (n=244). The primary endpoint of adju...
Source: Cardiology Research and Practice - October 26, 2018 Category: Cardiology Authors: Obeid S, Frangieh AH, Räber L, Yousif N, Gilhofer T, Yamaji K, Jaguszewski M, Aghlmandi S, Adams J, Bockhorn Y, Templin C, Stähli BE, Jüni P, Rodondi N, Mach F, Roffi M, Windecker S, Maier W, Nietlispach F, Matter CM, Klingenberg R, Lüscher TF Tags: Cardiol Res Pract Source Type: research