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Total 5918 results found since Jan 2013.

Worldwide Analysis of Radiology Access and Education for Stroke Care: View From Abroad From 14 Countries
The World Health Organization reports that stroke is among the leading causes of death in noncommunicable diseases worldwide despite advances in acute stroke care [1]. Early interventions in cerebrovascular accidents can prevent mortality and minimize debilitating effects of stroke. There have been major recent advancements in stroke care to intervene more quickly and effectively. We are entering a new era of stroke imaging-based treatment for late acute ischemic stroke. Recent neurointerventional trials, such as DAWN and DEFUSE 3, have transformed the way clinicians provide acute stroke care in the United States and provi...
Source: Journal of the American College of Radiology : JACR - September 6, 2018 Category: Radiology Authors: Jesus Uribe, Simon Ammanuel, Bhavya Rehani Tags: A View From Abroad Source Type: research

Lesion locations associated with persistent proprioceptive impairment in the upper limbs after stroke
We examined a large sample (n = 153) of stroke survivors longitudinally to determine which brain regions were associated with persistent post-stroke proprioceptive deficits. A robotic exoskeleton quantified two components of proprioception, position sense and kinesthesia (movement sense), at 2 weeks and again at 6 months post-stroke. A statistical region of interest (sROI) analysis compared the lesion-behaviour relationships of those subjects with cortical and subcortical stroke (n = 136). The impact of damage to brainstem and cerebellum (n = 17) was examined separately. Results indicate that damage to the ...
Source: NeuroImage: Clinical - October 5, 2018 Category: Radiology Source Type: research

Endovascular retrograde approach may be a better option for acute tandem occlusions stroke.
Conclusion For acute tandem occlusion stroke, favourable outcomes were better in patients undergoing retrograde therapy than in patients who received the anterograde approach. Future randomised trials are warranted to determine the optimal treatment. PMID: 30290710 [PubMed - as supplied by publisher]
Source: Interventional Neuroradiology - October 7, 2018 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Infarct Volume Predicts Hospitalization Costs in Anterior Circulation Large-Vessel Occlusion Stroke ADULT BRAIN
CONCLUSIONS: Final infarct volume was the strongest predictor of increased hospitalization costs in anterior circulation large-vessel occlusion stroke. Acute stroke therapies that reduce final infarct volume may not only improve clinical outcomes but may also prove cost-effective.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Streib, C. D., Rangaraju, S., Campbell, D. T., Winger, D. G., Paolini, S. L., Zhang, A. J., Jankowitz, B. T., Jadhav, A. P., Jovin, T. G. Tags: ADULT BRAIN Source Type: research

Mapping acute lesion locations to physiological swallow impairments after stroke
This study aimed to assess the statistical relationship between acute stroke lesion locations and impairment of specific aspects of swallow physiology. We performed lesion symptom mapping with 68 retrospectively recruited, acute, first-ever ischemic stroke patients. Lesions were determined on diffusion weighted MRI scans. Post-stroke swallow physiology was determined using the Modified Barium Swallow Study Impairment Profile (MBSImP©™). The relationship between brain lesion location and 17 physiological aspects of swallowing were tested using voxel-based and region-based statistical associations corrected for multiple c...
Source: NeuroImage: Clinical - January 22, 2019 Category: Radiology Source Type: research

Focal Hypoperfusion in Acute Ischemic Stroke Perfusion CT: Clinical and Radiologic Predictors and Accuracy for Infarct Prediction ADULT BRAIN
CONCLUSIONS: Compared with NCCT, perfusion CT doubles the sensitivity in detecting acute ischemic stroke. Focal hypoperfusion is independently predicted by stroke severity, cortical clinical deficits, nonlacunar supratentorial strokes, and shorter onset-to-imaging delays. A high proportion of patients with focal hypoperfusion developed infarction on subsequent imaging, as did some patients without focal hypoperfusion, indicating the complementarity of perfusion CT and MR imaging in acute ischemic stroke.
Source: American Journal of Neuroradiology - March 13, 2019 Category: Radiology Authors: Bill, O., Inacio, N. M., Lambrou, D., Wintermark, M., Ntaios, G., Dunet, V., Michel, P. Tags: ADULT BRAIN Source Type: research

Intravenous lysis treatment in acute stroke treatment-latest situation.
CONCLUSION: The i.v. thrombolysis treatment is still an essential treatment concept in acute stroke management. Further studies should be carried out with respect to the application in mothership stroke patients undergoing early endovascular treatment. PMID: 31065739 [PubMed - as supplied by publisher]
Source: Der Radiologe - May 6, 2019 Category: Radiology Authors: Haußmann A Tags: Radiologe Source Type: research

Mobile Stoke Unit : Changes in the concept of stroke care over time.
CONCLUSIONS: The MSU allows swifter treatment and a diagnosis-based triage decision at the scene of the emergency. It is now important to continue evaluating the clinical and socioeconomic benefit of these, at first glance expensive, preclinical tools and also continue analyzing special regional aspects as well as the pros and cons of the concepts. The recently established Prehospital Stroke Treatment Organization (PRESTO) represents a promising approach. PMID: 31143974 [PubMed - as supplied by publisher]
Source: Der Radiologe - May 28, 2019 Category: Radiology Authors: Kettner M, Walter S, Fassbender K Tags: Radiologe Source Type: research

Associations Between Diffusion Dynamics and Functional Outcome in Acute and Early Subacute Ischemic Stroke
ConclusionDiffusion dynamics are correlated with the clinical functional outcome of ischemic stroke. This correlation is independent of the effect of lesion volume and is specific to the time period between symptom onset and imaging. More effort is needed to further investigate the predictive value of diffusion-weighted imaging.
Source: Klinische Neuroradiologie - August 8, 2019 Category: Radiology Source Type: research

Direct Admission vs. Secondary Transfer to a  Comprehensive Stroke Center for Thrombectomy
ConclusionThese results confirm prior studies stating that DA to a  comprehensive stroke center leads to better outcome compared to ST in stroke patients undergoing thrombectomy.
Source: Klinische Neuroradiologie - October 10, 2019 Category: Radiology Source Type: research

Synthetic T2 mapping is correlated with time from stroke onset: a future tool in wake-up stroke management?
ConclusionsThe difference and ratio in T2 relaxation times were correlated with the onset time in stroke patients in the 4.5-h window. T2 mapping generated from synthetic MRI may become a relevant tool to select WUS patients with subtle FLAIR hyperintensities. Given that no definitive statement can be made about its usefulness in the 4.5-h windows, further study including patients with an onset time>  4.5 h is required.Key Points• The difference and ratio in T2 relaxation times are each individually correlated with the time from stroke onset in the 4.5-h window.• FLAIR rSI showed a poor correlation with the time ...
Source: European Radiology - November 4, 2019 Category: Radiology Source Type: research

Role of cerebral glutamate in post-stroke epileptogenesis
Publication date: Available online 5 November 2019Source: NeuroImage: ClinicalAuthor(s): John-Paul Nicolo, Terence J. O'Brien, Patrick KwanAbstractStroke is one of the most important causes of acquired epilepsy in the adult population. While factors such as cortical involvement and haemorrhage have been associated with increased seizure risk, the mechanisms underlying the development of epilepsy after stroke remain unclear. One hypothesised mechanism is an excitotoxic effect of abnormal glutamate release following a stroke. Cerebral extracellular glutamate levels are known to rise in the setting of acute stroke, and numero...
Source: NeuroImage: Clinical - November 6, 2019 Category: Radiology Source Type: research

Endovascular treatment decision-making in acute ischemic stroke patients with large vessel occlusion and low National Institutes of Health Stroke Scale: insights from UNMASK EVT, an international multidisciplinary survey
ConclusionDespite the limited evidence for endovascular therapy in acute stroke patients with low NIHSS, most physicians in this survey decided to proceed with endovascular therapy. A randomized controlled trial seems warranted.
Source: Neuroradiology - February 14, 2020 Category: Radiology Source Type: research

Is Histologic Thrombus Composition in Acute Stroke Linked to Stroke Etiology or to Interventional Parameters? INTERVENTIONAL
CONCLUSIONS: We interpreted the higher macrophage and platelet content in cardioembolic thrombi compared with large-artery atherosclerotic stenosis or embolic stroke of undetermined source thrombi as an indication that the latter type might be derived from an atherosclerotic plaque rather than from an undetermined cardiac source. The extent of thrombus fragmentation was associated with a more challenging mechanical thrombectomy and a higher lymphocyte content of the thrombi. Thus, thrombus fragmentation not only might be caused by the recanalization procedure but also might be a feature of a lymphocyte-rich, difficult-to-r...
Source: American Journal of Neuroradiology - April 8, 2020 Category: Radiology Authors: Goebel, J., Gaida, B.- J., Wanke, I., Kleinschnitz, C., Koehrmann, M., Forsting, M., Moenninghoff, C., Radbruch, A., Junker, A. Tags: INTERVENTIONAL Source Type: research

Location-Specific ASPECTS Paradigm in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis ADULT BRAIN
CONCLUSIONS: Our study indicated an unequal impact of some ASPECTS subregions in predicting outcomes of patients with acute ischemic stroke. Stroke laterality, imaging technique, and interventional technique subgroup analyses showed no differences among ASPECTS regions in predicting outcome. Investigation in larger cohorts is required to assess the association of ASPECTS with acute ischemic stroke outcome.
Source: American Journal of Neuroradiology - November 11, 2020 Category: Radiology Authors: Seyedsaadat, S. M., Neuhaus, A. A., Pederson, J. M., Brinjikji, W., Rabinstein, A. A., Kallmes, D. F. Tags: ADULT BRAIN Source Type: research