Is Histologic Thrombus Composition in Acute Stroke Linked to Stroke Etiology or to Interventional Parameters? [INTERVENTIONAL]

CONCLUSIONS:
We interpreted the higher macrophage and platelet content in cardioembolic thrombi compared with large-artery atherosclerotic stenosis or embolic stroke of undetermined source thrombi as an indication that the latter type might be derived from an atherosclerotic plaque rather than from an undetermined cardiac source. The extent of thrombus fragmentation was associated with a more challenging mechanical thrombectomy and a higher lymphocyte content of the thrombi. Thus, thrombus fragmentation not only might be caused by the recanalization procedure but also might be a feature of a lymphocyte-rich, difficult-to-retrieve subgroup of thrombi.

Source: American Journal of Neuroradiology - April 8, 2020 Category: Radiology Authors: Goebel, J., Gaida, B.- J., Wanke, I., Kleinschnitz, C., Koehrmann, M., Forsting, M., Moenninghoff, C., Radbruch, A., Junker, A. Tags: INTERVENTIONAL Source Type: research