Synthetic T2 mapping is correlated with time from stroke onset: a future tool in wake-up stroke management?

ConclusionsThe difference and ratio in T2 relaxation times were correlated with the onset time in stroke patients in the 4.5-h window. T2 mapping generated from synthetic MRI may become a relevant tool to select WUS patients with subtle FLAIR hyperintensities. Given that no definitive statement can be made about its usefulness in the 4.5-h windows, further study including patients with an onset time>  4.5 h is required.Key Points• The difference and ratio in T2 relaxation times are each individually correlated with the time from stroke onset in the 4.5-h window.• FLAIR rSI showed a poor correlation with the time from stroke onset.• T2 mapping, directly generated from synthetic MRI, may be a suitable quantitative marker to select safely WUS patients with subtle FLAIR hyperintensities for intravenous thrombolysis.
Source: European Radiology - Category: Radiology Source Type: research