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Specialty: Pediatrics
Condition: Hypertension

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Total 58 results found since Jan 2013.

Stroke in pediatric ECMO patients: analysis of the National Inpatient Sample (NIS) database
CONCLUSIONS: Over the years, there is an apparent increase in the diagnosis of stroke. All types of stroke in ECMO patients are associated with increased LOS, although mortality is increased in hemorrhagic and combined stroke only.IMPACT: Stroke is a commonly seen complication in pediatric patients supported by ECMO. Understanding the trends will help in identifying modifiable risk factors that predict poor outcomes in this patient population.PMID:35505077 | DOI:10.1038/s41390-022-02088-7
Source: Pediatric Research - May 3, 2022 Category: Pediatrics Authors: Chidiebere Ezetendu Orkun Baloglu Hasan F Othman Vanishree Nandakumar Samir Latifi Hany Aly Source Type: research

Birth weight as destiny?
In 1989, Barker et al reported a correlation between lower birth weights and increased risk for death in adulthood from ischemic heart disease in men born between 1911-1930 in England (Lancet 1989;2:577-80. doi: https://doi.org/10.1016/s0140-6736(89)90710-1). Many subsequent studies have affirmed the relationship between birth weight and conditions such as diabetes, hypertension, and obesity. In this volume of The Journal of Pediatrics, Lilja et al report an association between birth weight and stroke in adulthood.
Source: The Journal of Pediatrics - September 22, 2021 Category: Pediatrics Authors: Raye-Ann deRegnier Tags: The Editors' Perspectives Source Type: research

Primary Hypertension Beginning in Childhood and Risk for Future Cardiovascular Disease
Hypertension in adulthood continues to be a leading cause of morbidity and mortality worldwide.1 Hypertension in childhood is not uncommon, but due to the absence of data on future adverse outcomes (heart failure, stroke, kidney failure) hypertension has been defined in childhood as systolic or diastolic blood pressure (BP)>95th percentile of age, sex, and height adjusted normative BP data. The prevalence of childhood hypertension is approximately 4 percent, and the prevalence of elevated BP, a condition of higher risk for progression to hypertension, is approximately 10 percent.
Source: The Journal of Pediatrics - August 12, 2021 Category: Pediatrics Authors: Bonita Falkner, Empar Lurbe Tags: Medical Progress Source Type: research

Neurological complications in pediatric patients with SARS-CoV-2 infection: a systematic review of the literature
ConclusionsOur research highlights the large range of neurological manifestations and their presumed pathogenic pathways associated with SARS-CoV-2 infection in children. Nervous system involvement could be isolated, developing during COVID-19 or after its recovery, or arise in the context of a MIS-C. The most reported neurological manifestations are cerebrovascular accidents, reversible splenial lesions, GBS, benign intracranial hypertension, meningoencephalitis; ADEM is also a possible complication, as we observed in our patient. Further studies are required to investigate all the neurological complications of SARS-CoV-2...
Source: Italian Journal of Pediatrics - June 2, 2021 Category: Pediatrics Source Type: research

Monogenic Lupus with IgA Nephropathy Caused by Spondyloenchondrodysplasia with Immune Dysregulation
This report also highlights the rare coexistence of IgA nephropathy in monogenic lupus.
Source: Indian Journal of Pediatrics - March 13, 2021 Category: Pediatrics Source Type: research

How Common are Aortic Aneurysms?
Discussion Aortic root dilatation or thoracic aortic aneurysm occurs in 6:100,000 individuals > 50 years of age. It is due to aging, hypertension, hypercholesterolemia, and smoking. Tertiary syphilis was a cause in the preantibiotic era. Pediatric aneurysms are very uncommon but the exact prevalence is different due to the various causes. Aneurysms are due to genetic disorders, congenital anomalies or post-surgical repair. In pediatric patients with sudden cardiac deaths, 5.4% are due to ruptured thoracic aortic aneurysms. Learning Point Some causes of pediatric aneurysms include: Familial thoracic aneurysm and dissect...
Source: PediatricEducation.org - February 22, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

How Good is Photoscreening For Young Children ’ s Vision Problems?
This study showed that not only was smartphone photoscreening feasible, but was quite good at screening for potential vision problems. Smartphone photoscreening has the advantages of being more ubiquitously available and thus children in almost any location can be screened. A study of photoscreening using a handheld digital photoscreener in primary care offices validated the technology showing an overall referral rate of 10% to an ophthalmologist with suspected astigmatism, anisometropia and strabismus being the most common reasons. The overall positive predictive rate was 0.60. “…[O]ver 60% of children referre...
Source: PediatricEducation.org - January 4, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

The Use of Clevidipine for Hypertension in Pediatric Patients Receiving Mechanical Circulatory Support
Conclusions: In this pediatric cardiac cohort, clevidipine infusions were effective at hypertension management and were not associated with hypotensive or code events. This report details the largest cohort and longest duration of clevidipine administration within a pediatric population and did not demonstrate hypotensive events, even among neonatal populations. Clevidipine may be a reasonable cost-effective alternative antihypertensive medication compared to traditional short-acting agents.
Source: Pediatric Critical Care Medicine - December 1, 2020 Category: Pediatrics Tags: Online Cardiac Intensive Care Source Type: research

What Are the Main Acyanotic Congenital Heart Diseases?
Discussion Congenital heart diseases (CHD) are malformations of the heart and great vessels. It occurs in about 5-8/1000 live births. Cyanotic congenital heart disease is often noted perinatally because of cyanosis, respiratory distress and/or poor feeding or other distress type problems. A review can be found here. Acyanotic congenital heart disease (ACHD) can present at birth but often is seen in older children or adults unless the lesions are severe, especially obstructive lesions. Severe lesions may also cause cyanosis and distress type problems in patients also. Shunting lesions cause problems by diverting blood flo...
Source: PediatricEducation.org - August 17, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Do you hear what I hear? ECHO and autism
Autism spectrum disorder (ASD) is now estimated to occur in 1 of every 59 children in the US. The direct and indirect costs of caring for children and adults affected by ASD in 2015 dollars exceeded the cost of hypertension and stroke (Pediatrics 2020;145:e20193447). For these reasons and so many others, it is vital that general pediatricians and other primary care providers (PCPs) are able to recognize, screen, refer, and care for the many comorbidities that affect children and adolescents with ASD.
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Jane Oski Tags: The Editors' Perspectives Source Type: research

Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review.
This article summarizes the preclinical and clinical studies of arginine/citrulline in both adults and children, including currently available pharmacokinetic information. The pharmacology of arginine/citrulline is confounded by several patient-specific factors such as variations in baseline arginine/citrulline due to developmental ages and disease states. Currently available pharmacokinetic studies are insufficient to inform the optimal design of clinical studies, especially in children. Successful bench-to-bedside clinical translation of arginine supplementation awaits information from well-designed pharmacokinetic/pharm...
Source: Paediatric Drugs - March 5, 2020 Category: Pediatrics Authors: Rashid J, Kumar SS, Job KM, Liu X, Fike CD, Sherwin CMT Tags: Paediatr Drugs Source Type: research

Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review
This article summarizes the preclinical and clinical studies of arginine/citrulline in both adults and children, including currently available pharmacokinetic information. The pharmacology of arginine/citrulline is conf ounded by several patient-specific factors such as variations in baseline arginine/citrulline due to developmental ages and disease states. Currently available pharmacokinetic studies are insufficient to inform the optimal design of clinical studies, especially in children. Successful bench-to-bedsi de clinical translation of arginine supplementation awaits information from well-designed pharmacokinetic/pha...
Source: Pediatric Drugs - March 5, 2020 Category: Pediatrics Source Type: research

Understanding the Global Prevalence of Hypertension in Children and Adolescents
Hypertension is a major risk factor for the development of cardiovascular disease morbidity and mortality worldwide. Stroke, heart failure, myocardial infarction, and peripheral arterial disease are all outcomes associated with hypertension in adults. Hypertension is also considered to be a major cause of poorer disability-adjusted life-years. The prevalence of hypertension in adults has been debated in part because the definition of hypertension has changed over time. The association between blood pressure and cardiovascular disease is a continuous one, making the establishment of a cut point for hypertension difficult. H...
Source: JAMA Pediatrics - October 7, 2019 Category: Pediatrics Source Type: research

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news