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Psoriasis and metabolic and cardiovascular comorbidities in children: A systematic review.
CONCLUSION: This systematic review suggests that psoriasis in children is not associated with metabolic and cardiovascular comorbidities, except overweight and obesity, for which higher prevalence is clearly demonstrated in the literature. PMID: 30638928 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - January 10, 2019 Category: Pediatrics Authors: Badaoui A, Tounian P, Mahé E Tags: Arch Pediatr Source Type: research

Coming to Terms with Cardiovascular Morbidity after Early Term Birth
There is accumulating evidence that the consequences of even late preterm birth (34-37 weeks of gestation) reach well beyond the neonatal hospitalization into morbidities commonly seen in adulthood. The Barker hypothesis proposed that fetal adaptations to suboptimal intrauterine oxygen and nutrient supply result in changes in physiology and metabolism that subsequently predispose these individuals to an increased risk of cardiovascular diseases over their lifetime, including ischemic heart disease, stroke, diabetes, and hypertension.
Source: The Journal of Pediatrics - December 4, 2017 Category: Pediatrics Authors: Susan W. Denfield, S. Kristen Sexson Tejtel Tags: Editorials Source Type: research

Clinical and hematological profile in a newborn cohort with hemoglobin SC.
CONCLUSIONS: Clinical severity is variable in SC hemoglobinopathy. Several children have severe manifestations similar to those with SS disease. PMID: 29195085 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - November 28, 2017 Category: Pediatrics Authors: Rezende PV, Santos MV, Campos GF, Vieira LLM, Souza MB, Belisário AR, Silva CM, Viana MB Tags: J Pediatr (Rio J) Source Type: research

Art therapy with a child with pulmonary hypertension
An 11-year-old girl with life-limiting pulmonary hypertension was offered art therapy as a mode of communication about her condition. Hour-long therapy sessions were weekly, over 5 years during which her condition improved and she prepared to move on to college. No claims are made for art therapy apart from it being part of her treatment. She said she needed art therapy because when she tried to express her fears to her parents they would begin to cry. The images illustrate the process of art therapy in her adjustment to chronic illness. In the first session she made a clay butterfly (figure 1) alongside the art thera...
Source: Archives of Disease in Childhood - May 23, 2017 Category: Pediatrics Authors: McGregor, S., Morton, M. Tags: Journalology, Other rehabilitative therapies, Drugs: cardiovascular system, Stroke, Hypertension, Child health, Competing interests (ethics) Images in paediatrics Source Type: research

Extracorporeal membrane oxygenation in critically ill neonates and children.
Abstract Extracorporeal membrane oxygenation is used as a last resort during neonatal and pediatric resuscitation in case of refractory circulatory or respiratory failure under maximum conventional therapies. Different types of ECMO can be used depending on the initial failure. The main indications for ECMO are refractory respiratory failure (acute respiratory distress syndrome, status asthmaticus, severe pneumonia, meconium aspiration syndrome, pulmonary hypertension) and refractory circulatory failure (cardiogenic shock, septic shock, refractory cardiac arrest). The main contraindications are a gestational age u...
Source: Archives de Pediatrie - April 14, 2017 Category: Pediatrics Authors: Rambaud J, Guilbert J, Guellec I, Jean S, Durandy A, Demoulin M, Amblard A, Carbajal R, Leger PL Tags: Arch Pediatr Source Type: research

Moyamoya disease associated with kidney angiodysplasia in a child.
CONCLUSION: Moyamoya disease is a rare cause of stroke in children. Its association with renal angiodysplasia is unusual and may be responsible for malignant hypertension. Cognitive impairment and social dependence have recently been recognized as an important unresolved social issue. Affected children require medical-surgical, social, and psychological care. PMID: 28341559 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - March 21, 2017 Category: Pediatrics Authors: Dibi A, Maana Z, Jabourik F, Bentahila A Tags: Arch Pediatr Source Type: research

What Causes Hyperammonemia?
Discussion Reye’s syndrome (RS)is named for Dr. Douglas Reye who along with Drs. G. Morgan and J. Baral described encephalopathy and fatty accumulation and degeneration in children in a 1963 Lancet article. RS usually affects children but can occur at all ages. All organs can be affected but the liver and brain are primarily affected causing liver failure and encephalopathy as toxic metabolites (especially ammonia) accumulate, and intracranial hypertension and cerebral edema occurs. As the ammonia levels begin to rise (> 100 mg/dL) patients lose their appetite, have nausea and emesis and mental status changes whic...
Source: PediatricEducation.org - February 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Hypertension, Stroke and Abdominal Bruit: A Cryptic Extracranial Moyamoya!
Source: Indian Journal of Pediatrics - November 30, 2016 Category: Pediatrics Source Type: research

Public health for paediatricians: population screening
Introduction The concept of population screening—proactive identification of a condition, disease or predisease state in individuals who presume themselves to be healthy but may benefit from early treatment—is a simple one. The translation of this into a screening programme often raises ethical, conceptual and practical challenges. For clinicians used to dealing with patients symptomatically, there are several key differences to understand between treating patients symptomatically compared with the approach to supporting the delivery of a screening programme. There is a range of definitions of screening, which ...
Source: Archives of Disease in Childhood - Education and Practice - November 17, 2016 Category: Pediatrics Authors: Streetly, A., Madden, V. Tags: Drugs: CNS (not psychiatric), Stroke, Hypertension, Pregnancy, Reproductive medicine, Child health, Neonatal health, Screening (epidemiology), Health promotion, Screening (public health) Source Type: research

Reversible cerebral vasoconstriction syndrome: A rare pediatric cause of thunderclap headaches.
We report on a case of a 13-year-old boy presenting with acute severe headaches, triggered by physical exertion. His past medical history was uneventful. Moderate headache persisted between exacerbations for 4 weeks. He secondarily presented with signs of intracranial hypertension. Brain magnetic resonance angiography (MRA) revealed multifocal narrowing of the cerebral arteries. A glucocorticoid treatment was started based on the hypothesis of primary angiitis of the CNS. The symptoms rapidly improved, and repeat angiography at 3 months showed no vasoconstriction. Although pediatric cases are rare, RCVS should be considere...
Source: Archives de Pediatrie - September 13, 2016 Category: Pediatrics Authors: Trolliet M, Sevely A, Albucher JF, Nasr N, Hachon Lecamus C, Deiva K, Cheuret E Tags: Arch Pediatr Source Type: research

Different stroke(s)
A 13-year-old boy with mild learning difficulties presented to his district general hospital after an unwitnessed episode of collapse with vomiting but no loss of consciousness. He had 3 days of lethargy and intermittent occipital headaches waking him from sleep. Two days later, after another ‘funny turn’, he represented with right-side paraesthesia, weakness and word-finding difficulty. He had three previous ‘collapses’ over the last 6 months, including symptoms of transient dizziness, slurred speech, dribbling, difficulty swallowing and left-facial paraesthesia from which he had recovere...
Source: Archives of Disease in Childhood - Education and Practice - May 17, 2016 Category: Pediatrics Authors: Mundada, V., Krishnakumar, D., Chitre, M., Das, T. Tags: Oncology, Eye Diseases, Drugs: cardiovascular system, Echocardiography, Headache (including migraine), Infection (neurology), Neurooncology, Pain (neurology), Stroke, Hypertension, Ophthalmology, Valvar diseases, Radiology, Rheumatology, Dermatology, Clin Source Type: research

Adding Stress Management to Cardiac Rehab Cuts New Incidents in Half
Contact: Samiha Khanna Phone: 919-419-5069 Email: samiha.khanna@duke.edu https://www.dukehealth.org EMBARGOED FOR RELEASE until 4 p.m. (ET) on Monday, March 21, 2016 DURHAM, N.C. -- Patients recovering from heart attacks or other heart trouble could cut their risk of another heart incident by half if they incorporate stress management into their treatment, according to research from Duke Health. The findings, published March 21 in the American Heart Association journal Circulation, are the result of a randomized clinical trial of 151 outpatients with coronary heart disease who were enrolled in cardiac rehabilitation due t...
Source: DukeHealth.org: Duke Health Features - March 22, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

The effects of malnutrition on cardiac function in African children
Conclusions In this largest study to date, we found no significant difference in cardiac function between hospitalised children with and without severe acute malnutrition. Further study is needed to determine if cardiac function is diminished in unstable malnourished children.
Source: Archives of Disease in Childhood - January 20, 2016 Category: Pediatrics Authors: Silverman, J. A., Chimalizeni, Y., Hawes, S. E., Wolf, E. R., Batra, M., Khofi, H., Molyneux, E. M. Tags: Epidemiologic studies, Stroke, Hypertension, Radiology, Clinical diagnostic tests, Radiology (diagnostics) Original article Source Type: research

Familial Hypercholesterolemia: The Reason to Screen Children for Cholesterol Abnormalities
It is now well established that atherosclerosis begins in childhood and is progressive through adolescence and young adulthood, ultimately resulting in myocardial infarction and stroke in adults.1,2 It is also clear that the well-known risk factors for cardiovascular disease in adults, such as diabetes, hypertension, and dyslipidemia, are important in children and adolescents.3 The key issue with dyslipidemia appears to be elevated low-density lipoprotein (LDL)-C, which is clearly involved in the development and evolution of atherosclerotic plaque in arteries.
Source: The Journal of Pediatrics - December 27, 2015 Category: Pediatrics Authors: Stephen R. Daniels Tags: Editorial Source Type: research

Renin-Angiotensin System Blocker Fetopathy
Chronic hypertension in pregnant women is associated with significant maternal and fetal morbidity and mortality, and is thought to complicate approximately 5% of the 4 million pregnancies in the US annually.1 Pregnant women with chronic hypertension are at risk for developing adverse complications, such as maternal preeclampsia, stroke, renal failure, and death.2 In addition, adverse fetal outcomes, such as intrauterine growth restriction, preterm birth, and death, are more likely among pregnant women with chronic hypertension than those without.
Source: The Journal of Pediatrics - August 5, 2015 Category: Pediatrics Authors: Janet D. Cragan, Bessie A. Young, Adolfo Correa Tags: Editorial Source Type: research

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