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Specialty: Opthalmology

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Total 380 results found since Jan 2013.

Outcomes after medial rectus recession and lateral rectus plication for abducens nerve palsy: A retrospective study
CONCLUSION: Medial rectus recession with lateral rectus plication is an effective procedure in reducing diplopia and ocular deviation in unilateral acquired ANP and may be used as a first-line intervention regardless of the initial ocular motility limitation in abduction. The causes are mainly traumatic but remain undetermined in one case out of six.PMID:33775440 | DOI:10.1016/j.jfo.2020.07.025
Source: Journal Francais d Ophtalmologie - March 29, 2021 Category: Opthalmology Authors: N Boutellis R K Khanna P-J Pisella S Arsene Source Type: research

Relationships among visual acuity, risk of acute myocardial infarction, and stroke: a nationwide cohort study in south korea
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Source: Ophthalmic Epidemiology - March 17, 2021 Category: Opthalmology Authors: Gyule Han Jisang Han Kyungdo Han Tae-Young Chung Kyung-Sun Na Dong Hui Lim Source Type: research

Increased mortality after intravitreal injections of anti-VEGF for neovascular AMD among patients with prior stroke or acute myocardial infarction
Eye, Published online: 02 March 2021; doi:10.1038/s41433-021-01416-1Increased mortality after intravitreal injections of anti-VEGF for neovascular AMD among patients with prior stroke or acute myocardial infarction
Source: Eye - March 2, 2021 Category: Opthalmology Authors: Yu-Yen Chen Yun-Ju Lai Yung-Feng Yen Pesus Chou Source Type: research

Pulmonary Arteriovenous Malformation-Related Embolic Stroke Causing Thalamic Esotropia
No abstract available
Source: Journal of Neuro-Ophthalmology - February 25, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Splenial Restricted Diffusion as MRI Correlate of Diaschisis in a Blind Infant With Unilateral Posterior Cerebral Artery Stroke
Abstract: A 3-month-old male infant appeared on multiple clinical examinations to have acutely developed bilateral retrogeniculate blindness. Electroencephalography showed focal status epilepticus confined to the left posterior cerebral hemisphere. MRI demonstrated restricted diffusion in the domain of the left posterior cerebral artery consistent with acute stroke. Notably, the restricted diffusion extended across the midline in the splenium of the corpus callosum. This splenial sign may be the imaging correlate of cerebral diaschisis, a well-described phenomenon in which patients with new brain lesions develop acutel...
Source: Journal of Neuro-Ophthalmology - February 25, 2021 Category: Opthalmology Tags: Photo Essay Source Type: research

Neuro-Ophthalmologic Features and Outcomes of Thalamic Infarction: A Single-Institutional 10-Year Experience
Conclusions: Thalamic infarction, especially in paramedian territory, can cause a wide variety of neuro-ophthalmologic manifestations, including vertical gaze palsy, skew deviation, and third nerve palsy. Although most oculomotor abnormalities resolve spontaneously within a few months, some may persist for years when the deficits remain unimproved for more than 3 months after stroke.
Source: Journal of Neuro-Ophthalmology - February 25, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

The Clinical and Imaging Profile of Skew Deviation: A Study of 157 Cases
Conclusions: The amplitude of misalignment in skew deviation varies widely but is generally 5 PD or less. When misalignment is 3 PD or less, patients report blurred vision rather than diplopia. Skew deviation is usually accompanied by other neurologic signs reflecting brainstem dysfunction. Yet there is a small subgroup in which vertical misalignment is an isolated sign, and there are no supporting brain imaging abnormalities. The main cause of skew deviation is ischemic stroke, which affects not only the brainstem but also the thalamus. Diplopia from skew deviation frequently persists, in which case prism spectacles m...
Source: Journal of Neuro-Ophthalmology - February 25, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Mitochondrial DNA A3243G variant-associated retinopathy: Current perspectives and clinical implications
Cellular function and survival are critically dependent on the proper functionality of the mitochondrion. Neurodegenerative cellular processes including cellular adenosine triphosphate production, intermediary metabolism control, and apoptosis regulation are all mitochondrially mediated.The A to G transition at position 3243 in the mitochondrial MTTL1 gene that encodes for the leucine transfer RNA (m.3243A>G) causes a variety of diseases, including maternally inherited loss of hearing and diabetes syndrome (MIDD), mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS).
Source: Survey of Ophthalmology - February 18, 2021 Category: Opthalmology Authors: Razek Georges Coussa, Sumit Parikh, Elias I. Traboulsi Tags: Review article Source Type: research

Mitochondrial DNA A3243G Variant Associated Retinopathy: Current Perspectives & Clinical Implications
Cellular function and survival are critically dependent on the proper functionality of the mitochondrion. Neurodegenerative cellular processes including cellular adenosine triphosphate production, intermediary metabolism control, and apoptosis regulation are all mitochondrially mediated.The A to G transition at position 3243 in the mitochondrial MTTL1 gene that encodes for the leucine transfer RNA (m.3243A>G) causes a variety of diseases including maternally inherited loss of hearing and diabetes syndrome (MIDD), mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS).
Source: Survey of Ophthalmology - February 18, 2021 Category: Opthalmology Authors: Razek Georges Coussa, Sumit Parikh, Elias I. Traboulsi Source Type: research

Identification of a New Genetic Mutation Associated With Peters Anomaly
Conclusions: PA might be associated with the mutation c.181_189delinsAGGTTTCCG; p.Gly61Arg in the COL4A1 gene. The COL4A1 gene encodes for collagen IVα1, an essential component of basal membranes, and mutations are associated with an increased risk for renal and cerebrovascular disorders and stroke. This should be considered when advising and monitoring patients.
Source: Cornea - February 17, 2021 Category: Opthalmology Tags: Case Report Source Type: research

The Impact of Visual Impairment in Stroke (IVIS) Study – Evidence of Reproducibility
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Source: Neuro-Ophthalmology - February 3, 2021 Category: Opthalmology Authors: Fiona J. Rowe Lauren R. Hepworth Source Type: research

Assessment of Cerebral Vasomotor Reactivity in Patients With Primary Open-angle Glaucoma and Ocular Hypertension Using the Breath-Holding Index
Précis: Patients with ocular hypertension (OHT) do not show impaired cerebral vasodilation responses to hypercapnia but patients with primary open-angle glaucoma (POAG) do. Impaired vasoreactivity in patients with POAG may have neuronal or vascular origins and increase stroke risk. Purpose: To investigate changes in cerebral blood flow and cerebral vasomotor reactivity using the breath-holding index in patients with POAG and OHT, to examine whether these parameters contribute to the risk of ischemic stroke. Methods: Thirty patients with POAG, 30 patients with OHT, and 30 age- and sex-matched healthy cont...
Source: Journal of Glaucoma - February 1, 2021 Category: Opthalmology Tags: Clinical Science: Original Studies Source Type: research