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Diagnostic potential of routine brain MRI and high-resolution, multi-contrast vessel wall imaging in the detection of internal carotid artery dissection
Conclusion: The combination of brain MRI and clinical information could be used for the diagnosis of CAD and hrVWI should be sought for uncertain cases.
Source: Frontiers in Neurology - May 11, 2023 Category: Neurology Source Type: research

Craniovertebral Junction Anomalies: An Overlooked Cause of & #39;Posterior Circulation Stroke & #39;
Conclusions: CVJ anomalies can present as posterior circulation infarct. One must evaluate all patients with posterior circulation stroke, especially young patients, for possible CVJ anomalies. Dynamic lateral cervical spine X-ray is an important tool to diagnose AAD. CVJ anomalies represent a treatable cause of VAD.
Source: Neurology India - November 11, 2022 Category: Neurology Authors: Kanwaljeet Garg Vivek Tandon Rajinder Kumar P Sarat Chandra Shashank S Kale Bhawani Shankar Sharma Ashok K Mahapatra Source Type: research

Trends in admissions for intracranial dissections in the United States
Intracranial artery dissection (IAD) is rarer than cervical artery dissections (CeAD), and information is based on limited series with small cohorts. There are only several small-scale studies attempting to characterize the natural history of the disease. Herein, we analyze the prevalence of IADs in hospitalized patients using a national database.
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2022 Category: Neurology Authors: Waseem Wahood, Giuseppe Lanzino, Zafer Keser Source Type: research

Rural-Urban Differences in Diagnosed Cervical Artery Dissection in New York State
Conclusions: CeAD diagnosis correlates with population density as defined by rural-urban status. Our results could be due to underdiagnosis in rural areas or overdiagnosis with increasing urbanicity.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 14, 2022 Category: Neurology Source Type: research

Cervical Artery Dissection in Young Women: Risk of Recurrence During Subsequent Pregnancies
Conclusion In this study, there were no CAD recurrences during subsequent pregnancies or postpartum, irrespective of the type of delivery. Thus, pregnancy after a history of CAD appears to be safe.
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Assif, M., Lamy, C., De Gaalon, S., Caroit, Y., Bourcier, R., Preterre, C., Guillon, B. Tags: Stroke in young adults, Carotid artery dissection Research Source Type: research

Antiplatelet vs. Anticoagulation in Cervical Artery Dissection: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Conclusions: Compared with the antiplatelet group, the anticoagulation group has a lower risk of ischemic stroke without increasing bleeding risk when treating CAD. Anticoagulation seems to be superior over the antiplatelet in treating CAD but needs to be further tested by specifying several issues, such as location, initial symptom types, and treatment protocols.
Source: Frontiers in Neurology - November 24, 2021 Category: Neurology Source Type: research

Micro-Embolic Signals and Dissection: Association or Causation for Stroke? A Systematic Review and Meta-Analysis
Conclusions: Our meta-analysis showed 46% prevalence of MES in the studies which looked at acute stroke/TIA secondary to CAD using TCD. This finding supports the assumption that embolism may be a major cause of stroke in patients with dissection although this could be determined only in a small population.Cerebrovasc Dis
Source: Cerebrovascular Diseases - November 9, 2021 Category: Neurology Source Type: research

Internal carotid and vertebral artery dissections - a comparison of clinical, radiological and prognostic characteristics.
CONCLUSIONS AND CLINICAL IMPLICATIONS: In a series of patients with CeAD, we observed significant differences between VAD and ICAD in terms of clinical symptoms and radiological features. PMID: 33047785 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - October 13, 2020 Category: Neurology Authors: Kos J, Kos M, Jaworski J, Petit V, Wojtal K, Rejdak K Tags: Neurol Neurochir Pol Source Type: research

Differential Risk Factors and Outcomes of Ischemic Stroke due to Cervical Artery Dissection in Young Adults
Conclusions: While history of migraine and neck manipulation are significantly associated with CeAD, most of the traditional vascular risk factors for stroke are less prevalent in this group when compared to strokes due to other etiologies. For CeAD-related strokes, higher initial stroke severity and history of tobacco use may be associated with higher stroke-related disability, but overall, patients with CeAD have similar outcomes as compared to strokes due to other etiologies.Cerebrovasc Dis
Source: Cerebrovascular Diseases - September 25, 2020 Category: Neurology Source Type: research

Long-term outcome of cervical artery dissection
AbstractLong-term consequences of cervical artery dissection (CeAD), a major cause of ischemic stroke in young people, have been poorly investigated. The Italian Project on Stroke at Young Age – Cervical Artery Dissection (IPSYS CeAD) project is a multicenter, hospital-based, consecutively recruiting, observational, cohort study aimed to address clinically important questions about long-term outcome of CeAD patients, which are not covered by other large-scale registries. Patients with r adiologically diagnosed CeAD were consecutively included in the registry. Baseline demographic and clinical variables, as well as inform...
Source: Neurological Sciences - May 11, 2020 Category: Neurology Source Type: research

Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
Conclusion: The presence of atherosclerotic disease is considered rare in patients with cervical arterial dissection; however, our study found a high frequency of hypertension, smoking and dyslipidemia. The choice of antithrombotic remains controversial and will depend on the judgment of the medical professional; the clinical results with anticoagulation or antiaggregation were similar but there was more recanalization in the group treated with anticoagulation; its course was favorable in both situations. The recurrence of cervical arterial dissection and stroke is considered a rare event and its course is favorable.RESUMO...
Source: Arquivos de Neuro-Psiquiatria - September 23, 2019 Category: Neurology Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Propensity Score-Matched Analysis of Lesion Patterns in Stroke Patients With Patent Foramen Ovale and Patients With Spontaneous Intracranial Artery Dissection
Conclusion: The present study suggests that lesion patterns observed from DWI of patients with PFO and SIAD might provide clues to the etiology of infarcts. Single lesions (cortical or subcortical) might be a typical feature of PFO associated strokes, while multiple lesions in one vascular territory might be a specific feature of SIAD associated strokes. Introduction Both patent foramen ovale (PFO) and spontaneous intracranial artery dissection (SIAD) are important stroke risk factors, especially in young and middle-aged adults (1–3). About 25% of patients with ischemic stroke are cryptogenic (4), and PFO is ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Angiographical Identification of Intracranial, Atherosclerosis-Related, Large Vessel Occlusion in Endovascular Treatment
Conclusions Among only a few identification methods, the ICAS-LVO can be feasibly identified by angiographical findings. The identification of ICAS-LVO based on based on occlusion type, is a reliable and practical identification method for ICAS-LVO. Procedural details by occlusion type and its predictability to endovascular results were reported. Furthermore, occlusion type can be determined before or in the early stages of the procedure, which may be most helpful in setting up an optimal endovascular treatment strategy. Author Contributions J-HB established the study idea, designed the manuscript structure, acquired an...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Stroke in young adults: Five new things
Purpose of review The incidence of stroke in young adults is increasing, mainly driven by an increasing incidence of ischemic stroke in this population. We provide new information that has been recently presented regarding the risk factor prevalence, some specific etiologic causes, and management strategies in ischemic stroke in this population. Recent findings Recent studies indicate a rapid increase in traditional risk factors in young adults. New information regarding the management of patent foramen ovale in cryptogenic stroke and cervical artery dissection is available. Summary Stroke in young adults is a rapidly gr...
Source: Neurology Clinical Practice - December 10, 2018 Category: Neurology Authors: Bhatt, N., Malik, A. M., Chaturvedi, S. Tags: Stroke in young adults, Stroke prevention, All Cerebrovascular disease/Stroke, Carotid artery dissection Review Source Type: research

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