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The incidence and prevalence of epilepsy in the United Kingdom 2013 –2018: A retrospective cohort study of UK primary care data
The estimated incidence (50 –80 per 100,000 person-years) and prevalence rates (5–10 per 1000 person / year) for epilepsy have been found to be relatively consistent across high income countries [1–3]. Nevertheless, changes in demographics and risk factors mean that the epidemiology of epilepsy may change over time. For instance, in countries with an aging population, the increasing prevalence of diseases of old age such as stroke or dementia could increase the prevalence of epilepsy. Conversely, improved General Practitioner (GP) and specialist training, improved guidance for clinicians, better obstetric care and mo...
Source: Seizure: European Journal of Epilepsy - January 5, 2023 Category: Neurology Authors: S Wigglesworth, A Neligan, JM Dickson, A Pullen, E Yelland, T Anjuman, M Reuber Source Type: research

The Incidence and Prevalence of Epilepsy in the United Kingdom 2013-2018: a retrospective cohort study of UK primary care data.
The estimated incidence (50-80 per 100,000 person-years) and prevalence rates (5-10 per 1000 person / year) for epilepsy have been found to be relatively consistent across high income countries [1 –3]. Nevertheless, changes in demographics and risk factors mean that the epidemiology of epilepsy may change over time. For instance, in countries with an aging population, the increasing prevalence of diseases of old age such as stroke or dementia could increase the prevalence of epilepsy. Conve rsely, improved General Practitioner (GP) and specialist training, improved guidance for clinicians, better obstetric care and more ...
Source: Seizure: European Journal of Epilepsy - January 5, 2023 Category: Neurology Authors: S Wigglesworth, A Neligan, JM Dickson, A Pullen, E Yelland, T Anjuman, M Reuber Source Type: research

ASPECT Score and Its Application to Vasospasm in Aneurysmal Subarachnoid Haemorrhage: a Case –Control Study
AbstractDelayed cerebral ischaemia (DCI) is a significant complication of aneurysmal subarachnoid haemorrhage (aSAH) and is strongly associated with poorer outcome. The Alberta Stroke Program Early Computer Tomography (ASPECT) score is an established scoring tool, used in acute ischaemic stroke, to quantify early ischaemic changes on CT head scans. We aim to identify if ASPECT scoring correlates with functional outcome in DCI following aSAH. Retrospective case –control study. Inclusion criteria: admission to the Department of Neurosurgery at Leeds Teaching Hospitals NHS Trust (a tertiary neurosurgical centre in the Unite...
Source: Translational Stroke Research - August 9, 2022 Category: Neurology Source Type: research

Ischemic Stroke –A Scientometric Analysis
ConclusionsResearch in ischemic stroke has substantially increased over time. Scientists from the USA have the highest number of publications, followed by China and Germany. Measured by the H-index, the USA held the highest publication quality, followed by Germany and the UK. The scientific landscape was male-dominated with 67.7% of all first authors being male. Worldwide international collaborations play a major role in ischemic stroke research.
Source: Frontiers in Neurology - April 28, 2022 Category: Neurology Source Type: research

Effect of Sex on Outcomes of Mechanical Thrombectomy in Basilar Artery Occlusion: A Multicentre Cohort Study
Conclusion: Females achieved comparable functional outcomes compared with males after undergoing MT for BAO acute ischemic stroke.Cerebrovasc Dis
Source: Cerebrovascular Diseases - April 7, 2022 Category: Neurology Source Type: research

Regional Differences in Early BP Management After Acute Ischemic Stroke in the ENCHANTED International Randomized Controlled Trials
Conclusion: Regional variations in early BP management in acute stroke translated into differences in early BP control parameters.
Source: Frontiers in Neurology - August 27, 2021 Category: Neurology Source Type: research

What is the Price of the Potential for a Meaningful Recovery following Intracerebral Hemorrhage?
In this issue of the Journal of Stroke and Cerebrovascular Diseases, Vardanyan and colleagues report on the cost-utility of minimally invasive surgery (MIS) with thrombolysis for spontaneous intracerebral hemorrhage (ICH) from the perspective of the United Kingdom (UK) National Health Service (NHS)1 using data from the Minimally Invasive Surgery Plus Alteplase in Intracerebral Hemorrhage Evacuation (MISTIE III) trial2 and the UK Sentinel Stroke National Audit Programme (SSNAP).3 The economic evaluation revealed that the incremental cost-effectiveness ratio for MIS with thrombolysis fell significantly above the UK's Nationa...
Source: Journal of Stroke and Cerebrovascular Diseases - July 27, 2021 Category: Neurology Authors: Lourdes R. Carhuapoma, Avni Kapadia, Henry A. Glick, Daniel F. Hanley Source Type: research

Exploration of patient- and relative-reported outcomes of cognitive, emotional, and social function after encephalitis.
Conclusions: Individuals affected by encephalitis experience the most significant symptoms in the somatic, cognitive, and communication domains. Outcomes as assessed by relatives were notably worse than those assessed by individuals themselves in nearly all domains. PMID: 33356613 [PubMed - as supplied by publisher]
Source: Brain Injury - December 29, 2020 Category: Neurology Tags: Brain Inj Source Type: research

Impact of COVID-19 Pandemic on a Regional Stroke Thrombectomy Service in the United Kingdom
Conclusion: The COVID-19 pandemic has had a negative impact on the stroke admission numbers but not stroke thrombectomy rate, successful recanalization rate, or early neurological outcome. Internal delays actually improved during the COVID-19 pandemic. Further studies should examine the effects of the COVID-19 pandemic on longer term outcome.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 11, 2020 Category: Neurology Source Type: research

Impact of COVID-19 on stroke caseload in a major HyperAcute Stroke Unit
Northwick Park Hospital in London, United Kingdom (UK) is one of the busiest stroke units in the country and is located in one of the areas most heavily affected by the COVID-19 pandemic in the first half of 2020. Admissions to the stroke unit and changes during the peak of COVID-19 were reviewed. Compared with the previous year, mean 96 patients were admitted with suspected stroke during April and May 2020 compared with mean 116 per month in non-COVID periods, ratio 0.82, P=0.01. This reduction involved both strokes and mimics and was unlikely to have occurred by chance.
Source: Journal of Stroke and Cerebrovascular Diseases - October 5, 2020 Category: Neurology Authors: Fionn Mag Uidhir, Raj Bathula, Aravinth Sivagnanaratnam, Mudhar Abdul-Saheb, Joseph Devine, David L. Cohen Source Type: research

Impact of COVID-19 on stroke admissions, treatments, and outcomes at a comprehensive stroke centre in the United Kingdom
ConclusionsDuring the COVID-19 pandemic, the number of stroke admissions fell, and stroke severity increased. There was no statistically significant change in the delivery of thrombolysis and mechanical thrombectomy and no increase in mortality.
Source: Neurological Sciences - October 5, 2020 Category: Neurology Source Type: research

The interplay between COVID 19 and non-communicable diseases
Since the coronavirus designated as COVID-19 emerged as a global pathogen in late 2019, there has been rapid spread across the globe. After originating in China, several high-income countries such as Italy, Spain, United States, and the United Kingdom have had high case prevalence and high levels of mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - June 30, 2020 Category: Neurology Authors: Seemant Chaturvedi, Philip Gorelick Source Type: research

Prognosis of Asymptomatic Intracranial Stenosis in Patients With Transient Ischemic Attack and Minor Stroke
This cohort study examines the age-specific prevalence and prognosis of asymptomatic intracranial stenosis in British patients with transient ischemic attack and minor stroke.
Source: JAMA Neurology - May 26, 2020 Category: Neurology Source Type: research

Age- and Sex-Associated Impacts of Body Mass Index on Stroke Type Risk: A 27-Year Prospective Cohort Study in a Low-Income Population in China
Conclusions Being overweight increased the risk of both ischemic and hemorrhagic strokes; obesity was only associated with an increased risk of IS. Additionally, the positive association between BMI and stroke risk was only observed in participants aged <65 years and the associations differed between men and women. Being overweight increased the risk of both ischemic and hemorrhagic strokes in men and being underweight increased their risk of hemorrhagic stroke. In women, being overweight increased the hemorrhagic stroke risk, whereas obesity increased their IS risks. The high prevalence of hypertension and elevat...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Acupuncture for Post-stroke Shoulder-Hand Syndrome: A Systematic Review and Meta-Analysis
Conclusions: Acupuncture therapy seems effective for motor function, pain relief and activities of daily living in stroke patients with mild SHS, when it is used in combination with rehabilitation. The low certainty of evidence downgrades our confidence in making recommendations to clinical practice. Introduction Shoulder-hand syndrome (SHS) is a common condition among people who have had a stroke, with its reported prevalence ranging from 12% to 49% (1, 2). The main symptoms of SHS include pain, hyperalgesia, joint swelling and limitations in range of motion (ROM) (3). Post-stroke SHS is also named type I complex ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

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