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Specialty: Neurology
Condition: Hemorrhagic Stroke
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Total 7056 results found since Jan 2013.
Caveolin-1 aggravates neurological deficits by activating neuroinflammation following experimental intracerebral hemorrhage in rats
CONCLUSIONS: Our research revealed CAV1 aggravated neurological dysfunction in a rat ICH model. CAV1 knockdown exerted neuroprotective effect by suppressing microglia activation and neuroinflammation after ICH might via the C-Src/CAV1/IKK-β/NF-κB signaling pathway.PMID:37598879 | DOI:10.1016/j.expneurol.2023.114508
Source: Experimental Neurology - August 20, 2023 Category: Neurology Authors: Demao Cao Bing Li Cheng Cao Juyi Zhang Xiang Li Haiying Li Zhengquan Yu Haitao Shen Ming Ye Source Type: research
Deferoxamine Therapy for Hemorrhagic Transformation Following Brain Ischemia
Source: Translational Stroke Research - August 17, 2023 Category: Neurology Source Type: research
Thrombectomy with and without computed tomography perfusion imaging for large-vessel occlusion stroke in the extended time window: a meta-analysis of randomized clinical trials
ConclusionThese findings suggest that the choice of NCCT ± CTA (without CTP) for the assessment of mechanical thrombectomy within 6–24 h after LVO in the anterior circulation is not significantly different from CTP; instead, the choice of NCCT ± CTA significantly reduces the time from onset to arterial puncture.
Source: Frontiers in Neurology - August 17, 2023 Category: Neurology Source Type: research
Intravenous thrombolysis and endovascular therapy for acute ischemic stroke in COVID-19: a systematic review and meta-analysis
ConclusionCOVID-19 appears to have an adverse impact on acute ischemic stroke patients who undergo reperfusion therapy, leading to an elevated risk of any ICH, higher mortality and lower likelihood of favorable functional outcome.Systematic review registrationhttps://clinicaltrials.gov/, identifier CRD42022309785.
Source: Frontiers in Neurology - August 15, 2023 Category: Neurology Source Type: research
Intravenous thrombolysis and mechanical recanalization for acute ischemic stroke in deep brain stimulation patients: a case series
ConclusionIVT and MT were tolerated by four patients with ischemic stroke more than 6 months after DBS surgery without bleeding complications.
Source: Journal of Neurology - August 12, 2023 Category: Neurology Source Type: research
Identifying large vessel occlusion at first glance in telemedicine
ConclusionThese findings confirm that the presence of head and/or gaze deviation serves as a reliable biomarker in stroke-based telemedicine for the diagnosis of LVO, as well as a strong indicator for MT. Furthermore, this marker is just as reliable as the NIHSS score but easier to assess. We therefore suggest that any stroke patient who displays head and/or gaze deviation should immediately be scheduled for vessel imaging and subsequently transported to a MT-competent center.
Source: Journal of Neurology - August 12, 2023 Category: Neurology Source Type: research
Ticagrelor versus clopidogrel after intracranial stent angioplasty: a real-world study
ConclusionIn our study involving patients with acute ischemic stroke who had undergone intracranial stenting, aspirin-ticagrelor was not found to be superior to aspirin-clopidogrel in reducing the rate of ischemic vascular events. The risk of bleeding did not differ between the two groups. Aspirin-ticagrelor does not lower total restenosis and symptomatic restenosis risk at follow-up.
Source: Frontiers in Neurology - August 11, 2023 Category: Neurology Source Type: research
Endovascular Treatment for Acute Ischemic Stroke in China: a study protocol for a prospective, national, multi-center, registry study
This study plans to enroll a total of 3,000 consecutive patients who received EVT for LVO. All eligible patients are adults aged 18 years or older with acute LVO who received EVT and standard medical treatment according to the Chinese stroke guidelines and local practice.OutcomeThe primary outcome is functional independence (modified Rankin Scale score, mRS ≤ 2) at 90 days. The secondary outcomes include (1) the proportion of patients with mRS scores of 0–1 at 90 days, (2) distribution of mRS at 90 days, (3) changes in National Institutes of Health stroke scale (NIHSS) at 24 h, 48 h, and 12 days or discharge (whichever...
Source: Frontiers in Neurology - August 10, 2023 Category: Neurology Source Type: research
Interpretable machine learning for predicting 28-day all-cause in-hospital mortality for hypertensive ischemic or hemorrhagic stroke patients in the ICU: a multi-center retrospective cohort study with internal and external cross-validation
ConclusionsThe XGBoost model accurately predicted 28-day all-cause in-hospital mortality among hypertensive ischemic or hemorrhagic stroke patients admitted to the ICU. The SHAP method can provide explicit explanations of personalized risk prediction, which can aid physicians in understanding the model.
Source: Frontiers in Neurology - August 8, 2023 Category: Neurology Source Type: research
Response to: Aspirin and Subarachnoid Haemorrhage in the UK Biobank
Source: Translational Stroke Research - August 7, 2023 Category: Neurology Source Type: research
Assessment of rehabilitation following subarachnoid haemorrhage in China: findings from the Chinese Stroke Center Alliance
Rehabilitation improves functional recovery in subarachnoid hemorrhage (SAH) patients, and assessing patients for rehabilitation is the first step in this process. However, little is known about clinical pract...
Source: BMC Neurology - August 5, 2023 Category: Neurology Authors: Yi-Tong Chen, Mei-Ru Wu, Zi-Xiao Li, Hong-Qiu Gu, Qi Zhou, Dan-Dan Wang, Yong-Jun Wang and Xing-Quan Zhao Tags: Research Source Type: research
Dysphagia after ischemic and hemorrhagic stroke: A propensity-matched 20-year analysis of the national inpatient sample
Post-stroke dysphagia (PSD) is a common and debilitating complication of acute stroke associated with increased mortality and morbidity.1,2 Globally, 12.2 million strokes occur every year and 1 in 4 adults over the age of 25 will have a stroke within their lifetime.3 Of these, 87% of strokes are considered ischemic strokes (AIS) and 10% are hemorrhagic (ICH), both of which are associated with dysphagia as an adverse event.4 Recent studies have found that the prevalence of long-term PSD ranges from 42-50% and was an independent risk factor for prolonged hospital stay, institutionalization after discharge, poorer functional ...
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2023 Category: Neurology Authors: Vikram Vasan, Trevor A. Hardigan, Muhammad Ali, Margaret Downes, Alex Devarajan, Christina P. Rossitto, Braxton R. Schuldt, Ian C. Odland, Christopher P. Kellner, Johanna T. Fifi, J. Mocco, Shahram Majidi Source Type: research
The Functional Prognosis of Rescue Conscious Sedation During Mechanical Thrombectomy on Patients with Acute Anterior Circulation Ischemic Stroke: A Single-Center Retrospective Study
ConclusionCompared to LA, rescue CS during MT does not significantly improve the 90 days of good prognosis and reduce the incidence of sICH and mortality in patients with anterior circulation AIS. However, it has a significantly increased risk of poststroke pneumonia (PSP), particularly in patients with dysphagia.
Source: Neurology and Therapy - August 2, 2023 Category: Neurology Source Type: research
