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Specialty: Neurology
Condition: Hemorrhagic Stroke

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Total 7056 results found since Jan 2013.

Thrombectomy with or without Bridging Thrombolysis for Anterior Circulation Stroke
Conclusions: In this study, BT seems to yield better clinical and procedural outcomes with lower complication rates than d-MT. These findings may support the additional value of intravenous alteplase in anterior system strokes. Further large-scale, prospective, randomized-controlled studies will clarify the gray lines in this consensus, but this paper is important for reflecting the real-world data in developing countries.
Source: Neurology India - April 29, 2023 Category: Neurology Authors: Leyla Ramazanoglu Mehmet Kocak Isil Kalyoncu Aslan Yilmaz Onal Murat Velioglu Eren Gozke Source Type: research

Thrombectomy with or without Bridging Thrombolysis for Anterior System Stroke
Conclusions: In this study, BT seems to yield better clinical and procedural outcomes with lower complication rates than d-MT. These findings may support the additional value of intravenous alteplase in anterior system strokes. Further large-scale, prospective, randomized-controlled studies will clarify the gray lines in this consensus, but this paper is important for reflecting the real-world data in developing countries.
Source: Neurology India - April 29, 2023 Category: Neurology Authors: Leyla Ramazanoglu Mehmet Kocak Isil Kalyoncu Aslan Yilmaz Onal Murat Velioglu Eren Gozke Source Type: research

Activated neutrophil-derived exosomes contribute to blood-brain barrier damage and hemorrhagic transformation after cerebral ischemia/reperfusion
CONCLUSION: Neutrophils are abnormally recruited in HT after ischemic stroke, and are associated with cerebral hemorrhage. In vitro, A-Neu-derived exosomes facilitate BBB injury, which may be accomplished by exosomal transport of miRNAs.PMID:37116559 | DOI:10.1016/j.brainres.2023.148374
Source: Brain Research - April 28, 2023 Category: Neurology Authors: Ning Tang Xia-Rong Gong Hong Huang Qiang Meng Source Type: research

Low-dose vs. standard-dose intravenous alteplase for acute ischemic stroke with unknown time of onset
ConclusionThe effectiveness of low-dose alteplase might be comparable to that of standard-dose alteplase in AIS patients aged <70 years with favorable perfusion-imaging profiles in the unknown or extended time window but not in those aged ≥70 years. Furthermore, low-dose alteplase did not significantly reduce the risk of sICH compared to standard-dose alteplase.
Source: Frontiers in Neurology - April 28, 2023 Category: Neurology Source Type: research

Circadian variation in stroke onset: Differences between ischemic and hemorrhagic stroke and weekdays versus weekends
To delineate diurnal variation onset distinguishing ischemic from hemorrhagic stroke, wake from sleep onset, and weekdays from weekends/holidays.
Source: Journal of Stroke and Cerebrovascular Diseases - April 26, 2023 Category: Neurology Authors: Fatima Pariona-Vargas, Katherine T Mun, Eng H Lo, Sidney Starkman, Nerses Sanossian, Mersedeh Bahr Hosseini, Samuel Stratton, Marc Eckstein, Robin A. Conwit, David S Liebeskind, Latisha K Sharma, Neal M Rao, Kristina Shkirkova, Gilda Avila, May A Kim-Tens Source Type: research

Research advances in imaging markers for predicting hematoma expansion in intracerebral hemorrhage: a narrative review
ConclusionThe management of ICH presents a significant challenge, and identifying high-risk patients for HE is crucial to improving outcomes. The use of imaging markers for HE prediction can aid in the rapid identification of such patients and may serve as potential targets for anti-HE therapies in the acute phase of ICH. Therefore, further research is needed to establish the reliability and validity of these markers in identifying high-risk patients and guiding appropriate treatment decisions.
Source: Frontiers in Neurology - April 25, 2023 Category: Neurology Source Type: research

Ipsilateral weakness caused by ipsilateral stroke: A case series
There are few reported cases of ipsilateral weakness following ischemic or hemorrhagic stroke. In these rare cases, ipsilateral weakness is typically the result of damage to uncrossed components of the corticospinal tract (CST) which were recruited in response to previous CST injury.
Source: Journal of Stroke and Cerebrovascular Diseases - April 25, 2023 Category: Neurology Authors: Naim I. Kajtazi, Mohammed Bafaquh, Tanvir Rizvi, Souda El Sheikh, Juman Al Ghamdi, Razan Al Amoudi, Asma Al Jabbar, Kareem Al Shammari, Maher Saqqur, Saeed Al Ghamdi, Waleed Khoja, Andrew Demchuk, Fahmi Al Senani, Andreas R. Luft Source Type: research

Hemorrhagic Conversion of Acute Ischemic Stroke
AbstractStroke is a leading cause of morbidity and mortality worldwide; a serious complication of ischemic stroke is hemorrhagic transformation. Current treatment of acute ischemic stroke includes endovascular thrombectomy and thrombolytic therapy. Both of these treatment options are linked with increased risks of hemorrhagic conversion. The diagnosis and timely management of patients with hemorrhagic conversion is critically important to patient outcomes. This review aims to discuss hemorrhagic conversion of acute ischemic stroke including discussion of the pathophysiology, review of risk factors, imaging considerations, ...
Source: Neurotherapeutics - April 21, 2023 Category: Neurology Source Type: research

Close your eyes and see – stroke sequelae versus functional neurological disorder in a physician
The first author was a left-handed, 51-year-old nephrologist who experienced a neurologic event. She underwent neurosurgery complicated by hemorrhage. Post-operatively, she developed persistent vertigo and unilateral tongue pain which persisted for over five years. Early neuroimaging revealed expected encephalomalacia but no neuroanatomical basis for my symptoms. A functional neurological disorder was suspected, and she was seen by several psychiatrists and psychotherapists. However, she suspected a neuroanatomical lesion would better explain her unrelenting symptoms. After seeing many neurologists, a neuroanatomical diagn...
Source: European Neurology - April 20, 2023 Category: Neurology Source Type: research

Data lake-driven analytics identify nocturnal non-dipping of heart rate as predictor of unfavorable stroke outcome at discharge
ConclusionsOur data suggest that a lack of circadian HR modulation, specifically nocturnal non-dipping, is associated with short-term unfavorable functional outcome after stroke, and that including HR into machine learning-based prediction models may lead to improved stroke outcome prediction.
Source: Journal of Neurology - April 20, 2023 Category: Neurology Source Type: research

Optimizing  The Timing of Stereotactic Minimally Invasive Drainage for Hypertensive Intracerebral Hemorrhage
ConclusionsCustomized timing of stereotactic drainage may be superior to conventional fixed timing (within 12  h post-hemorrhage) in reducing post-surgery complications and promoting recovery, which supports the potential use of customized timing of stereotactic minimally invasive drainage as a new convention in clinics.
Source: Neurology and Therapy - April 18, 2023 Category: Neurology Source Type: research

Current status of endovascular treatment for older adults with acute large vessel occlusion stroke in China: subgroup analysis of ANGEL act registry
ConclusionWe found that patients less than or greater than 80 years of age share similar clinical outcomes, without increasing the risk of ICH and mortality.
Source: Frontiers in Neurology - April 18, 2023 Category: Neurology Source Type: research

Intra-arterial tenecteplase is safe and may improve the first-pass recanalization for acute ischemic stroke with large-artery atherosclerosis: the BRETIS-TNK trial
ConclusionThis is the first study to report that intra-arterial TNK during the first pass of EVT seems safe and feasible in AIS-LVO patients.
Source: Frontiers in Neurology - April 18, 2023 Category: Neurology Source Type: research