Caveolin-1 aggravates neurological deficits by activating neuroinflammation following experimental intracerebral hemorrhage in rats

CONCLUSIONS: Our research revealed CAV1 aggravated neurological dysfunction in a rat ICH model. CAV1 knockdown exerted neuroprotective effect by suppressing microglia activation and neuroinflammation after ICH might via the C-Src/CAV1/IKK-β/NF-κB signaling pathway.PMID:37598879 | DOI:10.1016/j.expneurol.2023.114508

Source: Experimental Neurology - August 20, 2023 Category: Neurology Authors: Demao Cao Bing Li Cheng Cao Juyi Zhang Xiang Li Haiying Li Zhengquan Yu Haitao Shen Ming Ye Source Type: research