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Specialty: Neurology
Condition: Epilepsy

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Total 1226 results found since Jan 2013.

Frequency and predictors of poststroke epilepsy after mechanical thrombectomy for large vessel occlusion stroke: results from a multicenter cohort study
ConclusionIn our study, patients with large vessel occlusion stroke receiving MT had a 9% prevalence of PSE over a median follow-up period of 6.5  years. Besides larger infarct size, presence of cerebral microbleeds on brain MRI predicted PSE occurrence.
Source: Journal of Neurology - September 2, 2023 Category: Neurology Source Type: research

Sleepiness in neurological disorders
Rev Neurol (Paris). 2023 Aug 17:S0035-3787(23)00986-4. doi: 10.1016/j.neurol.2023.07.005. Online ahead of print.ABSTRACTSleepiness is a frequent and underrecognized symptom in neurological disorders, that impacts functional outcomes and quality of life. Multiple and potentially additive factors might contribute to sleepiness in neurological disorders, including sleep quality alterations, circadian rhythm disorders, drugs, and sleep disorders including sleep apnea or central disorders of hypersomnolence. Physician awareness of the possible symptoms of hypersomnolence, and associated causes is of crucial importance to allow ...
Source: Revue Neurologique - August 19, 2023 Category: Neurology Authors: A-L Dubessy I Arnulf Source Type: research

Infraclavicular Catheter in MELAS Syndrome for Analgesic Purposes
M Onay, T Tanyel Kiremitçi, G Erdoğan Kayhan, D İlhan Algın, MS GüleçNeurology India 2023 71(4):764-766 MELAS syndrome is defined as mitochondrial myopathy accompanied by encephalopathy, lactic acidosis, myoclonus, stroke-like episodes. It has a progressive course, multi-systemic effects and severe complications. Myoclonic contractions are unresponsive to many anti-epileptic drugs; these contractions and spasms may lead to severe pain. Systemic analgesic drugs are not sufficient to control pain. Therefore, continuous brachial plexus blockage may be pr...
Source: Neurology India - August 18, 2023 Category: Neurology Authors: M Onay T Tanyel Kiremit & #231;i G Erdo & #287;an Kayhan D & #304;lhan Alg & #305;n MS G & #252;le & #231; Source Type: research

Telephone assistance for neurological diseases: a systematic review
CONCLUSIONS: Dementias are the diseases with more bibliographic references on their telephone assistance despite not being the most prevalent. The telephone is frequently used to administer diagnostic scales or support caregivers and is particularly useful in diseases that limit mobility and attending a medical practice.PMID:37466132 | DOI:10.33588/rn.7703.2022284
Source: Revista de Neurologia - July 19, 2023 Category: Neurology Authors: J M Trejo-Gabriel-Gal án E Cubo-Delgado Source Type: research

Preventing development of post-stroke hyperexcitability by optogenetic or pharmacological stimulation of cortical excitatory activity
Neurobiol Dis. 2023 Jul 17;184:106233. doi: 10.1016/j.nbd.2023.106233. Online ahead of print.ABSTRACTStroke is the most common cause of acquired epilepsy, but treatment for preventing the development of post-stroke epilepsy is still unavailable. Since stroke results in neuronal damage and death as well as initial loss of activity in the affected brain region, homeostatic plasticity may be trigged and contribute to an increase in network hyperexcitability that underlies epileptogenesis. Correspondingly, enhancing brain activity may inhibit hyperexcitability from enhanced homeostatic plasticity and prevent post-stroke epilep...
Source: Neurobiology of Disease - July 19, 2023 Category: Neurology Authors: Yadav Adhikari Cun-Gen Ma Zhi Chai Xiaoming Jin Source Type: research

Telephone assistance for neurological diseases: a systematic review
CONCLUSIONS: Dementias are the diseases with more bibliographic references on their telephone assistance despite not being the most prevalent. The telephone is frequently used to administer diagnostic scales or support caregivers and is particularly useful in diseases that limit mobility and attending a medical practice.PMID:37466132 | DOI:10.33588/rn.7703.2022284
Source: Revista de Neurologia - July 19, 2023 Category: Neurology Authors: J M Trejo-Gabriel-Gal án E Cubo-Delgado Source Type: research

TRPC Channels Activated by G Protein-Coupled Receptors Drive Ca2+ Dysregulation Leading to Secondary Brain Injury in the Mouse Model
AbstractCanonical transient receptor potential (TRPC) non-selective cation channels, particularly those assembled with TRPC3, TRPC6, and TRPC7 subunits, are coupled to Gαq-type G protein-coupled receptors for the major classes of excitatory neurotransmitters. Sustained activation of this TRPC channel-based pathophysiological signaling hub in neurons and glia likely contributes to prodigious excitotoxicity-driven secondary brain injury expansion. This was investigated in mouse models with selectiveTrpc gene knockout (KO). In adult cerebellar brain slices, application of glutamate and the class I metabotropic glutamate rece...
Source: Translational Stroke Research - July 18, 2023 Category: Neurology Source Type: research

Lifelong cerebrovascular disease burden among CADASIL patients: analysis from a global health research network
DiscussionEarly screening and targeted treatment strategies are warranted to help CADASIL patients with symptom management and risk mitigation.
Source: Frontiers in Neurology - July 14, 2023 Category: Neurology Source Type: research

External validation and comparison of clinical scores for predicting late seizures after intracerebral hemorrhage in Chinese patients
CONCLUSION: Our study showed that the CAVE, CAVS and LANE scores had similar AUCs for the occurrence of late seizures, but the LANE score had a relatively high PPV at the optimal cutoff score. Due to low evidence for using prophylactic antiseizure medications (ASM) in patients with ICH and poor availability of specialist stroke care in China, the LANE score with a cutoff score of 3 could be an applicable prediction tool in Chinese patients with ICH.PMID:37441984 | DOI:10.1016/j.yebeh.2023.109349
Source: Epilepsy and Behaviour - July 13, 2023 Category: Neurology Authors: Jiahe Lin Xianxian Li Jiahe Ye Guo Li Shanshan Huang Suiqiang Zhu Source Type: research

Case report: “Proust phenomenon” after right posterior cerebral artery occlusion
In this study, we provide the inaugural description of aversive odor-evoked autobiographical memories after stroke in the right hippocampal, parahippocampal, and thalamic nuclei. As potential underlying neural signatures of the phenomenon, we discuss the disinhibition of limbic circuits and impaired communication between the major networks, such as saliency, central executive, and default mode network.
Source: Frontiers in Neurology - July 13, 2023 Category: Neurology Source Type: research