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Specialty: General Medicine

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Total 11289 results found since Jan 2013.

In-thrombus thrombin secretion: a new diagnostic marker of atrial fibrillation in cryptogenic stroke
Isr Med Assoc J. 2022 Dec 1;25(12):853-854.ABSTRACTEndovascularly retrieved clots may be a potential resource for diagnosing stroke etiology. This method may influence secondary prevention treatment. We measure thrombin activity eluted by serially washing clots. We concluded that an assay measuring the change in thrombin in clots retrieved during acute stroke endovascular thrombectomy procedures may serve as a diagnostic marker of the origin of the clot. The suggested mechanism for these differences may be the clot location before its retrieval, with high blood flow causing thrombin washout in atherosclerotic clots, in con...
Source: The Israel Medical Association Journal - August 16, 2023 Category: General Medicine Authors: Ze'ev Itsekson Hayosh Eiman Abu Bandora Natalia Shelestovich Maya Nulman Mati Bakon Gal Yaniv Boris Khaitovitch Shmuel Balan Alexandra Gerasimova Tali Drori Stefan Mausbach Yvonne Schwammenthal Arnon Afek Joab Chapman Efrat Shavit Stein David Orion Source Type: research

Door-in-Door-out Times for Transfer of Patients With Stroke
This retrospective study involving patients with acute stroke requiring transfers from hospitals in the Get With the Guidelines –Stroke registry assesses patient and hospital factors associated with door-in-door-out times.
Source: JAMA - August 15, 2023 Category: General Medicine Source Type: research

Interventions for the uptake of evidence-based recommendations in acute stroke settings
CONCLUSIONS: We are uncertain whether a multifaceted implementation intervention compared to no intervention improves adherence to evidence-based recommendations in acute stroke settings, because the certainty of evidence is very low.PMID:37565934 | PMC:PMC10416310 | DOI:10.1002/14651858.CD012520.pub2
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Elizabeth A Lynch Lemma N Bulto Heilok Cheng Louise Craig Julie A Luker Kathleen L Bagot Tharshanah Thayabaranathan Heidi Janssen Elizabeth McInnes Sandy Middleton Dominique A Cadilhac Source Type: research

Pharmacological interventions for asymptomatic carotid stenosis
CONCLUSIONS: Although there is no high-certainty evidence to support pharmacological intervention, this does not mean that pharmacological treatments are ineffective in preventing ischaemic cerebral events, morbidity, and mortality. High-quality RCTs are needed to better inform the best medical treatment that may reduce the burden of carotid stenosis. In the interim, clinicians will have to use other sources of information.PMID:37565307 | PMC:PMC10401652 | DOI:10.1002/14651858.CD013573.pub2
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Caroline Nb Clezar Carolina Dq Flumignan Nicolle Cassola Luis Cu Nakano Virginia Fm Trevisani Ronald Lg Flumignan Source Type: research

Interventions for the uptake of evidence-based recommendations in acute stroke settings
CONCLUSIONS: We are uncertain whether a multifaceted implementation intervention compared to no intervention improves adherence to evidence-based recommendations in acute stroke settings, because the certainty of evidence is very low.PMID:37565934 | DOI:10.1002/14651858.CD012520.pub2
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Elizabeth A Lynch Lemma N Bulto Heilok Cheng Louise Craig Julie A Luker Kathleen L Bagot Tharshanah Thayabaranathan Heidi Janssen Elizabeth McInnes Sandy Middleton Dominique A Cadilhac Source Type: research

Pharmacological interventions for asymptomatic carotid stenosis
CONCLUSIONS: Although there is no high-certainty evidence to support pharmacological intervention, this does not mean that pharmacological treatments are ineffective in preventing ischaemic cerebral events, morbidity, and mortality. High-quality RCTs are needed to better inform the best medical treatment that may reduce the burden of carotid stenosis. In the interim, clinicians will have to use other sources of information.PMID:37565307 | PMC:PMC10401652 | DOI:10.1002/14651858.CD013573.pub2
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Caroline Nb Clezar Carolina Dq Flumignan Nicolle Cassola Luis Cu Nakano Virginia Fm Trevisani Ronald Lg Flumignan Source Type: research

Interventions for the uptake of evidence-based recommendations in acute stroke settings
CONCLUSIONS: We are uncertain whether a multifaceted implementation intervention compared to no intervention improves adherence to evidence-based recommendations in acute stroke settings, because the certainty of evidence is very low.PMID:37565934 | PMC:PMC10416310 | DOI:10.1002/14651858.CD012520.pub2
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Elizabeth A Lynch Lemma N Bulto Heilok Cheng Louise Craig Julie A Luker Kathleen L Bagot Tharshanah Thayabaranathan Heidi Janssen Elizabeth McInnes Sandy Middleton Dominique A Cadilhac Source Type: research

Pharmacological interventions for asymptomatic carotid stenosis
CONCLUSIONS: Although there is no high-certainty evidence to support pharmacological intervention, this does not mean that pharmacological treatments are ineffective in preventing ischaemic cerebral events, morbidity, and mortality. High-quality RCTs are needed to better inform the best medical treatment that may reduce the burden of carotid stenosis. In the interim, clinicians will have to use other sources of information.PMID:37565307 | PMC:PMC10401652 | DOI:10.1002/14651858.CD013573.pub2
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Caroline Nb Clezar Carolina Dq Flumignan Nicolle Cassola Luis Cu Nakano Virginia Fm Trevisani Ronald Lg Flumignan Source Type: research

Exoskeletal wearable robot on ambulatory function in patients with stroke: a protocol for an international, multicentre, randomised controlled study
This study is an international, multicentre, randomised controlled study at five institutions with a total of 150 patients with subacute stroke. Participants will be randomised into two groups (75 patients in the robot-assisted gait training (RAGT) group and 75 patients in the control group). The gait training will be performed with a total of 20 sessions (60 min/session); 5 sessions a week for 4 weeks. The RAGT group will receive 30 min of gait training using an exoskeleton (ANGEL LEGS M20, Angel Robotics) and 30 min of conventional gait training, while the control group will receive 60 min conventional gait training. In ...
Source: BMJ Open - August 11, 2023 Category: General Medicine Authors: Chang, W. H., Kim, T.-W., Kim, H. S., Hanapiah, F. A., Kim, D. H., Kim, D. Y. Tags: Open access, Rehabilitation medicine Source Type: research

Cardiovascular effects of rivaroxaban in heart failure patients with sinus rhythm and coronary disease with and without diabetes: a retrospective international cohort study from COMMANDER-HF
Conclusions In COMMANDER-HF a diagnosis of diabetes conferred higher rates of cardiovascular events that, with exception of ischaemic stroke, was not substantially reduced by rivaroxaban. Rivaroxaban was associated with reduced risk of ischaemic stroke for patients with and without diabetes. Trial registration number NCT01877915; Post-results.
Source: BMJ Open - August 11, 2023 Category: General Medicine Authors: Sharma, A., Caldeira, D., Razaghizad, A., Pinto, F. J., van Veldhuisen, D. J., Mehra, M. R., Lam, C. S. P., Cleland, J., Anker, S. D., Greenberg, B., Ferreira, J. P., Zannad, F. Tags: Open access, Cardiovascular medicine Source Type: research

Early neurological deterioration in acute ischemic stroke
ConclusionOur study showed END may be associated with poor functional outcome in AIS patients. Higher blood glucose at admission and low serum albumin may be statistically significant causing END. Future prospective cohort with larger sample size may confirm the findings.
Source: Irish Journal of Medical Science - August 10, 2023 Category: General Medicine Source Type: research

Aspirin ‐induced urticaria in a recently diagnosed ischemic stroke patient: A case report and literature review
We report a case of a 53-year-old male, recently diagnosed with a stroke, who presented with complaints of multiple rashes over the trunk and upper extremities with aspirin. NSAIDs induced urticarial are usually neglected by physicians during diagnosis.
Source: Clinical Case Reports - August 8, 2023 Category: General Medicine Authors: Abhinav Dahal, Sushant Gautam, Aliza Shakya, Ashmita Pant, Kriti Bhandari, Shumneva Shrestha, Sajina Shrestha, Abhigan Babu Shrestha Tags: CASE REPORT Source Type: research

Integrative-interpersonal dynamic therapy for poststroke depression (INID): study protocol of a randomised controlled pilot trial
Introduction Depression is the most frequent psychiatric disorder following stroke, affecting about one-third of stroke survivors. Patients experience poorer recovery, lower quality of life and higher mortality compared with stroke survivors without depression. Despite these well-known malign consequences, poststroke depression (PSD) is regarded underdiagnosed and undertreated. Evidence of beneficial effects of psychotherapy to treat PSD remains scarce and inconclusive and is limited by heterogeneity in design, content and timing of the intervention. This pilot study aims to assess the feasibility of a newly developed inte...
Source: BMJ Open - August 8, 2023 Category: General Medicine Authors: Volz, M., Mundiyanapurath, S., Schauenburg, H., Meuth, S. G., Wild, B., Werheid, K., Barber, J. P., Schäfer, R., Beerbaum, L., Dinger, U. Tags: Open access, Rehabilitation medicine Source Type: research

AHA News: During a Stroke, Her Doctor Son Got Her Quick Care, Then Her Granddaughter Penned a Story
MONDAY, Aug. 7, 2023 (American Heart Association News) -- Rekha Desai planned to play Legos and blocks with her 2-year-old grandson, Kaveh, as she watched him in his Atlanta home. But Rekha never arrived. Instead, the 73-year-old lay in a gurney...
Source: Drugs.com - Daily MedNews - August 7, 2023 Category: General Medicine Source Type: news

Effect of arteriosclerotic intracranial arterial vessel wall enhancement on downstream collateral flow
CONCLUSIONS: Arteriosclerotic IAVWE significantly reduced downstream collateral flow and affected relevant neurological deficits. It was an independent factor affecting downstream collateral flow and NIHSS scores, which should be a focus of future studies.TRIAL REGISTRATION: ChiCTR.org.cn, ChiCTR2100053661.PMID:37545035 | DOI:10.1097/CM9.0000000000002307
Source: Chinese Medical Journal - August 7, 2023 Category: General Medicine Authors: Liqun Yan Zhenchang Wang Guoshi Wang Zhenzhong Li Jin Yan Yaping Hou Boyuan Huang Qianbo Dong Xiaodan Mu Wei Cao Pengfei Zhao Source Type: research