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Procedure: Carotid Endarterectomy

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Total 2934 results found since Jan 2013.

Utilization of Carotid Revascularization for Ischemic Stroke/TIA: A Canadian Perspective (P5.276)
Conclusions:Use of CEA/CAS in patients with acute ischemic stroke/TIA admitted to hospitals in Canada has doubled over the last decade. Differences in utilization by age, sex and across provinces are seen.Disclosure: Dr. Najm has nothing to disclose. Dr. Lindsay has nothing to disclose. Dr. Hill has nothing to disclose. Dr. Demchuk has nothing to disclose. Dr. Menon has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Najm, M., Lindsay, P., Hill, M. D., Demchuk, A., Menon, B. Tags: SubAcute Interventional Therapies in Cerebrovascular Disease Source Type: research

Primary Prevention of Stroke in Chronic Kidney Disease Patients: A Scientific Update
Background: Although chronic kidney disease (CKD) is an independent risk factor for stroke, official recommendations for the primary prevention of stroke in CKD are generally lacking.Summary: We searched PubMed and ISI Web of Science for randomised controlled trials, observational studies, reviews, meta-analyses and guidelines referring to measures of stroke prevention or to the treatment of stroke-associated risk factors (cardiovascular disease in general and atrial fibrillation (AF), arterial hypertension or carotid artery disease in particular) among the CKD population. The use of oral anticoagulation in AF appears safe...
Source: Cerebrovascular Diseases - January 9, 2018 Category: Neurology Source Type: research

Investigation of S-Nitrosoglutathione in stroke: A systematic review and meta-analysis of literature in pre-clinical and clinical research.
CONCLUSIONS: Pre-clinical studies showed positive benefit of GSNO in animal stroke models. The meta-analysis of clinical studies demonstrated that GSNO is effective in reducing embolic signals in patients with symptomatic internal carotid artery stenosis undergoing carotid endarterectomy or stenting. Further investigation of this molecule is warranted. PMID: 32119935 [PubMed - as supplied by publisher]
Source: Experimental Neurology - February 27, 2020 Category: Neurology Authors: Liu S, Zheng H, Yu W, Ramakrishnan V, Shah S, Gonzalez LF, Singh I, Graffagnino C, Feng W Tags: Exp Neurol Source Type: research

Surgical Approaches to Stroke Risk Reduction
This article examines the evidence for using the available options. RECENT FINDINGS Carotid endarterectomy is an effective treatment option for reducing the risk of stroke in appropriately selected patients. Patients should be stratified for future stroke risk based on both the degree of stenosis and the presence of symptoms referable to the culprit lesion. Carotid stenting is also useful in reducing stroke risk, again in carefully selected patients. Because of the publication of significant data regarding both carotid endarterectomy and carotid artery stenting in the last several years, selection can be far more person...
Source: CONTINUUM: Lifelong Learning in Neurology - April 1, 2020 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Stroke Prevention: Little-Known and Neglected Aspects
Combining available therapies has the potential to reduce the risk of stroke by 80% or more. A comprehensive review of all aspects of stroke prevention would be very lengthy; in this narrative review, we focus on some aspects of stroke prevention that are little-known and/or neglected. These include the following: (1) implementation of a Mediterranean diet; (2) B vitamins to lower homocysteine; (3) coordinated approaches to smoking cessation; (4) intensive lipid-lowering therapy; (5) lipid lowering in the elderly; (6) physiologically individualized therapy for hypertension based on renin/aldosterone phenotyping; (7) avoidi...
Source: Cerebrovascular Diseases - May 27, 2021 Category: Neurology Source Type: research

Extracranial carotid plaque hemorrhage predicts ipsilateral stroke recurrence in patients with carotid atherosclerosis - a study based on high-resolution vessel wall imaging MRI
CONCLUSIONS: Carotid intraplaque hemorrhage is strongly associated with recurrent ischemic events and could predict recurrent ipsilateral stroke.PMID:35764942 | DOI:10.1186/s12883-022-02758-3
Source: Atherosclerosis - June 28, 2022 Category: Cardiology Authors: Fengli Che Donghua Mi Anxin Wang Yi Ju Binbin Sui Xiaokun Geng Xihai Zhao Xingquan Zhao Source Type: research

Carotid Plaque Characteristics Predict Recurrent Ischemic Stroke and TIA: The PARISK (Plaque At RISK) Study
CONCLUSIONS: IPH and total plaque volume are independent risk factors for recurrent ipsilateral ischemic stroke or TIA in patients with mild-to-moderate carotid stenosis. These plaque characteristics improve current decision making. Validation studies to implement plaque characteristics in clinical scoring tools are needed. (PARISK: Validation of Imaging Techniques [PARISK]; NCT01208025).PMID:36202450 | DOI:10.1016/j.jcmg.2022.04.003
Source: Atherosclerosis - October 6, 2022 Category: Cardiology Authors: Dianne H K van Dam-Nolen Martine T B Truijman Anja G van der Kolk Madieke I Liem Floris H B M Schreuder Eric Boersma Mat J A P Daemen Werner H Mess Robert J van Oostenbrugge Antonius F W van der Steen Daniel Bos Peter J Koudstaal Paul J Nederkoorn Jeroen Source Type: research

Risk index for predicting perioperative stroke, myocardial infarction, or death risk in asymptomatic patients undergoing carotid endarterectomy
Objective: The latest guidelines recommend performance of carotid endarterectomy (CEA) on asymptomatic patients with high-grade carotid stenosis, only if the combined perioperative stroke, myocardial infarction (MI), or death risk is ≤3%. Our objective was to develop and validate a risk index to estimate the combined risk of perioperative stroke, MI, or death in asymptomatic patients undergoing elective CEA.Methods: Asymptomatic patients who underwent an elective CEA (n = 17,692) were identified from the 2005-2010 National Surgical Quality Improvement Program, a multicenter, prospective database. Multivariable logistic ...
Source: Journal of Vascular Surgery - November 19, 2012 Category: Surgery Authors: Prateek K. Gupta, Bala Ramanan, Jason N. MacTaggart, Abhishek Sundaram, Xiang Fang, Himani Gupta, Jason M. Johanning, Iraklis I. Pipinos Tags: Clinical research studies Source Type: research

Carotid plaque hemorrhage on MRI strongly predicts recurrent ischemia and stroke
Abstract OBJECTIVES:There is a recognized need to improve selection of patients with carotid artery stenosis for carotid endarterectomy (CEA). We assessed the value of MRI defined carotid plaque hemorrhage (MRIPH) to predict recurrent ipsilateral cerebral ischemic events, and stroke in symptomatic carotid stenosis. METHODS:179 symptomatic patients with ≥50% stenosis were prospectively recruited, underwent carotid MRI and were clinically followed up until CEA, death or ischemic event. MRIPH was diagnosed if the plaque signal intensity was >150% that of the adjacent muscle. Event‐free survival analysis was done using ...
Source: Annals of Neurology - March 6, 2013 Category: Neurology Authors: Akram A. Hosseini, Neghal Kandiyil, Shane T. MacSweeney, Nishath Altaf, Dorothee P. Auer Tags: Research Article Source Type: research

Carotid plaque hemorrhage on magnetic resonance imaging strongly predicts recurrent ischemia and stroke
ObjectiveThere is a recognized need to improve selection of patients with carotid artery stenosis for carotid endarterectomy (CEA). We assessed the value of magnetic resonance imaging (MRI)‐defined carotid plaque hemorrhage (MRIPH) to predict recurrent ipsilateral cerebral ischemic events, and stroke in symptomatic carotid stenosis. MethodsOne hundred seventy‐nine symptomatic patients with ≥50% stenosis were prospectively recruited, underwent carotid MRI, and were clinically followed up until CEA, death, or ischemic event. MRIPH was diagnosed if the plaque signal intensity was >150% that of the adjacent muscle. Ev...
Source: Annals of Neurology - June 4, 2013 Category: Neurology Authors: Akram A. Hosseini, Neghal Kandiyil, Shane T. S. MacSweeney, Nishath Altaf, Dorothee P. Auer Tags: Original Article Source Type: research

A Clinical Rule (Sex, Contralateral Occlusion, Age, and Restenosis) to Select Patients for Stenting Versus Carotid Endarterectomy: Systematic Review of Observational Studies With Validation in Randomized Trials Clinical Sciences
Conclusions— The SCAR rule is potentially useful to identify patients in whom CAS has a similar risk of perioperative stroke or death to CEA.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Touze, E., Trinquart, L., Felgueiras, R., Rerkasem, K., Bonati, L. H., Meliksetyan, G., Ringleb, P. A., Mas, J.-L., Brown, M. M., Rothwell, P. M., in collaboration with the Carotid Stenting Trialists' Collaboration Tags: Clinical Sciences Source Type: research

A Retrospective Study on Early Carotid Endarterectomy within 48 Hours after Transient Ischemic Attack and Stroke in Evolution
Conclusions: CEA can be performed with an acceptable risk in properly selected symptomatic patients within 48 hours after TIA or SIE. The benefits of early CEA in symptomatic patients include the prevention of recurrent stroke.
Source: Annals of Vascular Surgery - September 5, 2013 Category: Surgery Authors: Emanuele Ferrero, Michelangelo Ferri, Andrea Viazzo, Carmelo Labate, Giuseppe Berardi, Alberto Pecchio, Salvatore Piazza, Matteo Ripepi, Franco Nessi Tags: Clinical Research Source Type: research

Long-Term Follow-Up Study of Endarterectomy Versus Angioplasty in Patients With Symptomatic Severe Carotid Stenosis Trial Clinical Sciences
Conclusions— The long-term benefit–risk balance of carotid stenting versus endarterectomy for symptomatic carotid stenosis favored endarterectomy, a difference driven by a lower risk of procedural stroke after endarterectomy. Both techniques were associated with low and similar long-term risks of recurrent ipsilateral stroke beyond the procedural period. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00190398.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Mas, J.-L., Arquizan, C., Calvet, D., Viguier, A., Albucher, J.-F., Piquet, P., Garnier, P., Viader, F., Giroud, M., Hosseini, H., Hinzelin, G., Favrole, P., Henon, H., Neau, J.-P., Ducrocq, X., Padovani, R., Milandre, L., Rouanet, F., Wolff, V., Saudeau, Tags: Secondary prevention, Carotid Stenosis, Carotid endarterectomy, Angioplasty and Stenting Clinical Sciences Source Type: research

64-detector CT angiography within 24 hours after carotid endarterectomy and correlation with postoperative stroke.
CONCLUSIONS CTA within 24 hours of CEA demonstrates characteristic anatomical findings. CCA step-offs and ECA flaps are relatively common and clinically insignificant, whereas ICA/CCA flaps and thrombi are less frequently seen and are associated with postoperative stroke/TIA. PMID: 25555168 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 2, 2015 Category: Neurosurgery Authors: Gallati CP, Jain M, Damania D, Kanthala AR, Jain AR, Koch GE, Kung NT, Wang HZ, Replogle RE, Jahromi BS Tags: J Neurosurg Source Type: research