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Procedure: Carotid Endarterectomy

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Total 2934 results found since Jan 2013.

Urgent Carotid Surgery and Stenting May Be Safe After Systemic Thrombolysis for Stroke Clinical Sciences
Conclusions— Urgent carotid endarterectomy or carotid artery stenting after thrombolysis for stroke may be safe without increased risk of serious complications.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Koraen-Smith, L., Troeng, T., Bjorck, M., Kragsterman, B., Wahlgren, C.-M., on behalf of the Swedish Vascular Registry and the Riks-Stroke Collaboration, This work was supported by the Steering Committee of the Swedish Vascular Registry (Swedvasc):, Krags Tags: Acute Cerebral Infarction, Carotid Stenosis, Emergency treatment of Stroke, Carotid endarterectomy, Angioplasty and Stenting Clinical Sciences Source Type: research

Timing of Carotid Revascularization Procedures After Ischemic Stroke Brief Report
Background and Purpose—In 2006, the American Heart Association recommended that carotid revascularization generally occurs within 2 weeks of stroke based on data from 2 trials of carotid endarterectomy (CEA). We aimed to determine whether the time between stroke and CEA or carotid artery stenting (CAS) has decreased and whether the proportion of procedures occurring within 14 days has increased.Methods—Using validated International Classification of Diseases, Ninth Revision, Clinical Modification codes and administrative claims data from nonfederal hospitals in CA, FL, and NY, we identified patients with ischemic strok...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Michael Reznik, Hooman Kamel, Gino Gialdini, Ankur Pandya, Babak B. Navi, Ajay Gupta Tags: Secondary Prevention, Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Symptomatic Carotid Atherosclerotic Disease: Correlations Between Plaque Composition and Ipsilateral Stroke Risk Clinical Sciences
Conclusions— Features of the vulnerable carotid plaque, including plaque thrombus, low fibrous content, macrophage infiltration, and microvessel density, correlate with predicted stroke risk. This study provides a basis for plaque imaging studies focused on stroke risk stratification.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Howard, D. P. J., van Lammeren, G. W., Rothwell, P. M., Redgrave, J. N., Moll, F. L., de Vries, J.-P. P. M., de Kleijn, D. P. V., den Ruijter, H. M., de Borst, G. J., Pasterkamp, G. Tags: Pathophysiology, Carotid Stenosis, Primary and Secondary Stroke Prevention, Carotid endarterectomy Clinical Sciences Source Type: research

Deficiency of the Stroke Relevant HDAC9 Gene Attenuates Atherosclerosis in Accord With Allele-Specific Effects at 7p21.1 Basic Sciences
Conclusions— Our results suggest that HDAC9 represents the disease-relevant gene at the stroke and coronary artery disease risk locus on 7p21.1, and that risk alleles in this region mediate their effects through increased HDAC9 expression. Targeted inhibition of HDAC9 might be a viable strategy to prevent atherosclerosis.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Azghandi, S., Prell, C., van der Laan, S. W., Schneider, M., Malik, R., Berer, K., Gerdes, N., Pasterkamp, G., Weber, C., Haffner, C., Dichgans, M. Tags: Clinical genetics, Risk Factors, Genomics, Genetics of Stroke Basic Sciences Source Type: research

Residual High-Grade Stenosis After Recanalization of Extracranial Carotid Occlusion in Acute Ischemic Stroke Clinical Sciences
Conclusions— A residual high-grade stenosis of the extracranial ICA occurs in 1 of 6 patients with a symptomatic occlusion in the acute stage of cerebral ischemia. Because this may have implications for secondary prevention, we recommend follow-up imaging in these patients within a week after the event. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00880113.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Luitse, M. J. A., Velthuis, B. K., Dauwan, M., Dankbaar, J. W., Biessels, G. J., Kappelle, L. J., on behalf of the Dutch Acute Stroke Study Group, Majoie, Roos, Duijm, Keizer, van der Lugt, Dippel, Droogh-de Greve, Bienfait, van Walderveen, Wermer, Lyckla Tags: CT and MRI, Acute Cerebral Infarction, Carotid Stenosis Clinical Sciences Source Type: research

Nonstenotic carotid plaque on CT angiography in patients with cryptogenic stroke
Conclusions: Large but nonstenotic carotid artery plaque is considerably more common ipsilateral than contralateral to cryptogenic stroke, suggesting that nonstenotic plaque is an underrecognized cause of stroke. We measured plaque size using CT angiography, a method that could be easily implemented in clinical practice.
Source: Neurology - August 14, 2016 Category: Neurology Authors: Coutinho, J. M., Derkatch, S., Potvin, A. R. J., Tomlinson, G., Kiehl, T.-R., Silver, F. L., Mandell, D. M. Tags: CT, Stroke prevention, All Cerebrovascular disease/Stroke, Embolism ARTICLE Source Type: research

Plaque Inflammation and Unstable Morphology Are Associated With Early Stroke Recurrence in Symptomatic Carotid Stenosis Clinical Sciences
Conclusions— Plaque inflammation and other vulnerability features were associated with highest risk of stroke recurrence and may represent therapeutic targets for future stroke prevention trials.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Marnane, M., Prendeville, S., McDonnell, C., Noone, I., Barry, M., Crowe, M., Mulligan, N., Kelly, P. J. Tags: Pathophysiology Clinical Sciences Source Type: research

Early Carotid Revascularization Reduces Readmission for Recurrent Ischemic Stroke in Acute Ischemic Stroke Patients: Analysis of United States Nationwide Readmissions Database (P4.294)
Conclusions:Patients with ischemic stroke undergoing carotid revascularization during the initial hospitalization have significantly lower risk of readmission related to another ischemic strokeDisclosure: Dr. Chaudhry has nothing to disclose. Dr. Gheith has nothing to disclose. Dr. Gu has nothing to disclose. Dr. Afzal has nothing to disclose. Dr. Rahman has nothing to disclose. Dr. Riaz has nothing to disclose. Dr. Sachdeva has nothing to disclose. Dr. Sattar has nothing to disclose. Dr. Razak has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chaudhry, S., Gheith, T., Gu, S., Afzal, M.-R., Rahman, H., Riaz, A., Sachdeva, G., Sattar, A., Razak, A., Qureshi, A. Tags: In-Hospital Stroke Care Source Type: research

Risk of Stroke From New Carotid Artery Occlusion in the Asymptomatic Carotid Surgery Trial-1 Clinical Sciences
Conclusions— New occlusions were uncommon after carotid endarterectomy in ACST-1. During long-term follow-up, occlusion and stroke were commoner among patients with ≥70% stenosis, most of whom had not undergone carotid endarterectomy. Occlusion was an independent prognostic risk factor for occurrence of stroke.
Source: Stroke - May 24, 2013 Category: Neurology Authors: den Hartog, A. G., Halliday, A. W., Hayter, E., Pan, H., Kong, X., Moll, F. L., de Borst, G. J., on behalf of the Asymptomatic Carotid Surgery Trial Collaborators Tags: Acute Cerebral Infarction, Carotid Stenosis Clinical Sciences Source Type: research

Long-Term Outcome After Carotid Artery Stenting: A Population-Based Matched Cohort Study Clinical Sciences
Conclusions— In this nationwide cohort study, CAS was associated with an increased long-term risk of ipsilateral stroke and death during after the perioperative phase when compared with CEA.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Jonsson, M., Lindstrom, D., Gillgren, P., Wanhainen, A., Malmstedt, J. Tags: Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke, Stenosis, Vascular Disease Clinical Sciences Source Type: research

CYP2C19 Loss-of-Function Associated with First-Time Ischemic Stroke in Non-surgical Asymptomatic Carotid Artery Stenosis During Clopidogrel Therapy
This study measures effect ofCYP2C19 genotype on ischemic stroke risk during clopidogrel therapy for asymptomatic, extracranial carotid stenosis patients. Using deidentified electronic health records, patients were selected for retrospective cohort using administrative code for carotid stenosis, availability ofCYP2C19 genotype result, clopidogrel exposure, and established patient care. Patients with intracranial atherosclerosis, aneurysm, arteriovenous malformation, prior ischemic stroke, or observation time<1 month were excluded. Dual antiplatelet therapy patients were included. Patients with carotid endarterectomy or ...
Source: Translational Stroke Research - February 21, 2021 Category: Neurology Source Type: research

Short Time Interval Between Neurologic Event and Carotid Surgery Is Not Associated With an Increased Procedural Risk Clinical Sciences
Conclusions—The time interval between the index event and carotid endarterectomy was not associated with the risk of any in-hospital stroke or death in patients with symptomatic carotid stenosis in Germany. In clinically stable patients, carotid endarterectomy might, therefore, be performed safely as soon as possible after the neurological index event.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Tsantilas, P., Kuehnl, A., Konig, T., Breitkreuz, T., Kallmayer, M., Knappich, C., Schmid, S., Storck, M., Zimmermann, A., Eckstein, H.–H. Tags: Complications, Quality and Outcomes, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Age and the fuzzy edges of embolic stroke of undetermined source: Implications for trials
After an acute ischemic stroke, clinicians pursue further diagnostic assessment to identify the most plausible causes and tailor secondary prevention strategies. Available treatments with a high level of evidence for reducing recurrence stroke risk might include long-term oral anticoagulation in patients with a major-risk cardioembolic source (atrial fibrillation, prosthetic valves, etc), carotid endarterectomy in minor ischemic stroke related to moderate to severe internal carotid artery atherosclerotic stenosis, and best-practice medical management in those with lacunar stroke due to cerebral small vessel disease.1 Howev...
Source: Neurology - August 7, 2017 Category: Neurology Authors: Charidimou, A. Tags: Stroke in young adults, All Clinical trials, All Cerebrovascular disease/Stroke, Embolism, Infarction EDITORIALS Source Type: research

Reducing Delay of Carotid Endarterectomy in Acute Ischemic Stroke Patients: A Nationwide Initiative Clinical Sciences
Conclusions— Establishing time limits of 4 days to ultrasound examination of the carotids and of 2 weeks to CEA from onset of stroke followed by a systematic multidisciplinary monitoring and auditing of processes was associated with a substantial increase in the proportion of acute ischemic stroke patients who undergo CEA within 2 weeks in Denmark.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Witt, A. H., Johnsen, S. P., Jensen, L. P., Hansen, A. K., Hundborg, H. H., Andersen, G. Tags: Carotid Stenosis, Carotid endarterectomy Clinical Sciences Source Type: research

Recurrent stroke in symptomatic carotid stenosis awaiting revascularization: A pooled analysis
Conclusions: We found high risk of recurrent ipsilateral ischemic events within the 14-day time period currently recommended for CEA. Randomized trials are needed to determine the benefits and safety of urgent vs subacute carotid revascularization within 14 days after symptom onset.
Source: Neurology - February 8, 2016 Category: Neurology Authors: Johansson, E., Cuadrado-Godia, E., Hayden, D., Bjellerup, J., Ois, A., Roquer, J., Wester, P., Kelly, P. J. Tags: All Cerebrovascular disease/Stroke ARTICLE Source Type: research