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Total 305 results found since Jan 2013.

Surgical embolectomy for internal carotid artery terminus occlusion
Abstract The aim of this study was to assess the efficacy and safety of surgical embolectomy for internal carotid artery terminus (ICA-T) occlusion. Twenty-five consecutive patients with acute ischemic stroke attributed to embolic ICA-T occlusion who underwent surgical embolectomy were retrospectively reviewed. Twenty-four patients were examined based on magnetic resonance imaging, with one patient included based on a computed tomography scan. Recanalization rate, recanalization time, complications, National Institutes of Health Stroke Scale (NIHSS) score improvement at 1 month, and modified Rankin Scale (mRS) at...
Source: Neurosurgical Review - May 12, 2015 Category: Neurosurgery Source Type: research

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock.
CONCLUSIONS: Available evidence suggests that IABP may have a beneficial effect on some haemodynamic parameters. However, this did not result in survival benefits so there is no convincing randomised data to support the use of IABP in infarct-related cardiogenic shock. PMID: 25812932 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - April 2, 2015 Category: Journals (General) Authors: Unverzagt S, Buerke M, de Waha A, Haerting J, Pietzner D, Seyfarth M, Thiele H, Werdan K, Zeymer U, Prondzinsky R Tags: Cochrane Database Syst Rev Source Type: research

Effects of candesartan in acute stroke on vascular events during long‐term follow‐up: results from the Scandinavian Candesartan Acute Stroke Trial (SCAST)
ConclusionsTreatment with candesartan in the acute phase of stroke was not associated with clear long‐term clinical benefits. This result supports the conclusion from trials with short‐term follow‐up, that blood pressure lowering treatment with candesartan should not be given routinely to patients with acute stroke and raised blood pressure.
Source: International Journal of Stroke - March 23, 2015 Category: Neurology Authors: Astrid G. Hornslien, Else C. Sandset, Jannicke Igland, Andreas Terént, Gudrun Boysen, Philip M. W. Bath, Gordon D. Murray, Eivind Berge Tags: Research Source Type: research

Cardiovascular highlights from non-cardiology journals
Why is Atherosclerotic Cardiovascular Disease Risk Overestimated by the ACC/AHA Pooled Cohort Equation? The 2013 ACC/AHA Cholesterol Guidelines expand the recommendations for statin use to populations previously felt to be at lower risk. Central to risk-estimation in these guidelines is a new equation for determination of atherosclerotic cardiovascular disease (ASCVD) risk. However, this risk model has been criticized overestimating ASCVD risk in validation studies of the model. Using the Women's Health Study, Cook et al. sought to determine the reasons for risk-overestimation by the ACC/AHA model. Among 27,542 women, 632 ...
Source: Heart - February 25, 2015 Category: Cardiology Authors: Bradley, S. M. Tags: Journal scan Source Type: research

Effects of Blood Pressure-Lowering Treatment in Different Subtypes of Acute Ischemic Stroke Brief Reports
Conclusions— The results suggest that the effect of blood pressure–lowering treatment with candesartan may differ according to different types of acute ischemic stroke, but this needs to be confirmed in future trials. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Sandset, E. C., Jusufovic, M., Sandset, P. M., Bath, P. M. W., Berge, E., on behalf of the SCAST Study Group Tags: Cerebrovascular disease/stroke, Clinical Studies Brief Reports Source Type: research

Carotid artery stenting in nonagenarians: are there benefits in surgically treating this high risk population?
Conclusions CAS in nonagenarian patients carried increased risk of perioperative ischemic events, compared with contemporary trial results in symptomatic and asymptomatic patients. Further, mean survival time postprocedure fell short of guidelines for receiving procedural benefit. Although larger scale multicenter research is needed, we recommend careful consideration of overall health status when contemplating stenting in nonagenarians.
Source: Journal of NeuroInterventional Surgery - February 12, 2015 Category: Neurosurgery Authors: Wach, M. M., Dumont, T. M., Shakir, H. J., Snyder, K. V., Hopkins, L. N., Levy, E. I., Siddiqui, A. H. Tags: Editor''s choice, Ischemic stroke Source Type: research

Availability of highly sensitive troponin assays and acute coronary syndrome care: insights from the SNAPSHOT registry.
CONCLUSION: Use of hs troponin testing of patients hospitalised with possible ACS was associated with an increased rate of non-invasive cardiac investigations and fewer inhospital adverse events. PMID: 25588444 [PubMed - in process]
Source: Med J Aust - January 17, 2015 Category: Journals (General) Authors: Cullen L, French JK, Briffa TG, Redfern J, Hammett CJ, Brieger DB, Parsonage WA, Lefkovits J, Ellis C, Astley C, Howell TE, Elliott JM, Chew DP Tags: Med J Aust Source Type: research

Cardiovascular highlights from non-cardiology journals
Dual Antiplatelet Therapy Beyond 1-year after Percutaneous Coronary Interventions for Stable Coronary Artery Disease Results in Harm The benefit of extended dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) is uncertain. The ARTIC-Interruption Trial examined discontinuation of DAPT at 1-year after PCI vs continuation for an additional 6–18 months. The study randomized patients 1-year after PCI to continuation (N=635) or interruption (N=624) groups, and examined the primary composite endpoint of death, myocardial infarction, stent thrombosis, stroke, or urgent revascularization over a med...
Source: Heart - January 14, 2015 Category: Cardiology Authors: Bradley, S. M. Tags: Journal scan Source Type: research

Rivaroxaban vs. vitamin K antagonists for cardioversion in atrial fibrillation
Conclusion Oral rivaroxaban appears to be an effective and safe alternative to VKAs and may allow prompt cardioversion. Name of the trial registry Clinicaltrials.gov; Trial registration number: NCT01674647.
Source: European Heart Journal - December 14, 2014 Category: Cardiology Authors: Cappato, R., Ezekowitz, M. D., Klein, A. L., Camm, A. J., Ma, C.-S., Le Heuzey, J.-Y., Talajic, M., Scanavacca, M., Vardas, P. E., Kirchhof, P., Hemmrich, M., Lanius, V., Meng, I. L., Wildgoose, P., van Eickels, M., Hohnloser, S. H., on behalf of the X-Ve Tags: ESC Hot Line Barcelona Source Type: research

Effects of blood pressure lowering in patients with acute ischemic stroke and carotid artery stenosis
ConclusionsThere is no clear evidence that the effect of candesartan is qualitatively different in patients with carotid artery stenosis, but there are signals that patients with severe stenosis are at particularly high risk of stroke progression and poor functional outcome.
Source: International Journal of Stroke - December 3, 2014 Category: Neurology Authors: Mirza Jusufovic, Else Charlotte Sandset, Philip M. W. Bath, Björn W. Karlson, Eivind Berge, Tags: Research Source Type: research

10 Good Reasons To Get A Flu Shot
By Melaina Juntti for Men's Journal How many times have you heard you should get a flu shot? There's good reason for the hype: Over the past few years, the influenza vaccine has prevented millions of flu cases and tens of thousands of related hospitalizations, according to Centers for Disease Control and Prevention. Although an increasing number of people are getting vaccinated every year, more than half of American men still aren't doing it, for a variety of reasons, most of which aren't backed by science. "Men have this macho sense that if they do get the flu, they can tough it out," says William Schaffner, M.D., chair...
Source: Healthy Living - The Huffington Post - November 29, 2014 Category: Consumer Health News Source Type: news

Acoustic radiation force impulse imaging (ARFI) on an IVUS circular array.
Authors: Patel V, Dahl JJ, Bradway DP, Doherty JR, Lee SY, Smith SW Abstract Our long-term goal is the detection and characterization of vulnerable plaque in the coronary arteries of the heart using intravascular ultrasound (IVUS) catheters. Vulnerable plaque, characterized by a thin fibrous cap and a soft, lipid-rich necrotic core is a precursor to heart attack and stroke. Early detection of such plaques may potentially alter the course of treatment of the patient to prevent ischemic events. We have previously described the characterization of carotid plaques using external linear arrays operating at 9 MHz. In add...
Source: Ultrasonic Imaging - November 25, 2014 Category: Radiology Tags: Ultrason Imaging Source Type: research

Application of 68Ga-PRGD2 PET/CT for αvβ3-integrin Imaging of Myocardial Infarction and Stroke
Conclusions: 68Ga-PRGD2 uptake was observed around the ischemic region in both MI and stroke patients, which was correlated with the disease phase and severity. The different image patterns and uptake levels in MI and stroke patients warrant further investigations.
Source: Theranostics - November 15, 2014 Category: Molecular Biology Authors: Yi Sun, Yong Zeng, Yicheng Zhu, Feng Feng, Weihai Xu, Chenxi Wu, Bing Xing, Weihong Zhang, Peiling Wu, Liying Cui, Renzhi Wang, Fang Li, Xiaoyuan Chen, Zhaohui Zhu Tags: Research Paper Source Type: research

Barriers and opportunities in assessing calls to emergency medical communication centre - a qualitative study
Conclusion: Barriers in assessing the call to the EMCC were associated with contradictory information, the absence of a primary problem, or the structure of the call. Opportunities were associated with a clear symptom description that was also repeated, and the RN?s use of different communication strategies such as closed loop communication.
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - November 11, 2014 Category: Emergency Medicine Authors: Veronica LindströmKristiina HeikkiläKatarina BohmMaaret CastrènAnn-Charlotte Falk Source Type: research