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Total 305 results found since Jan 2013.

Brain Scans Give Clues to Stress-Heart Attack Link
THURSDAY, March 24, 2016 -- A new brain study might help explain why a high level of stress is linked to an increased risk of heart attack and stroke. Increased activity in the amygdala -- the fear center of the brain -- appears to create an immune...
Source: Drugs.com - Daily MedNews - March 24, 2016 Category: Journals (General) Source Type: news

Decline in dementia rate offers “cautious hope”
“The number of Americans with Alzheimer’s disease and other dementias will grow each year as the size and proportion of the U.S. population age 65 and older continue to increase. The number will escalate rapidly in coming years as the baby boom generation ages.” 2015 Alzheimer’s disease Facts and Figures Despite these alarming projections, a report from a recent issue of the New England Journal of Medicine (NEJM) offered a few words of encouragement. Researchers from the longstanding Framingham study found that the rate of dementia has declined over the course of three decades. Framingham researchers had been study...
Source: New Harvard Health Information - March 9, 2016 Category: Consumer Health News Authors: Beverly Merz Tags: Alzheimer's Disease Behavioral Health Brain and cognitive health Caregiving Healthy Aging Memory Mental Health Prevention cognitive decline dementia Source Type: news

Simultaneous coronary and carotid revascularisation
Conclusion According to our experiences and results, the simultaneous performance of CEA and CABG in patients with severe coexisting carotid artery disease who require coronary revascularization has proved to be a safe and efficacious operative strategy in these high-risk patients.
Source: Cor et Vasa - February 23, 2016 Category: Cardiology Source Type: research

Dynamic Magnetic Resonance Angiography Provides Collateral Circulation and Hemodynamic Information in Acute Ischemic Stroke Brief Reports
Conclusions— As a fast, direct, feasible, noninvasive, and reliable method to assess site of occlusion, collateral circulation and hemodynamic alterations, dMRA provides profound insights in acute stroke.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Hernandez-Perez, M., Puig, J., Blasco, G., Perez de la Ossa, N., Dorado, L., Davalos, A., Munuera, J. Tags: Imaging, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke
Conclusions: Our data identify a genetic contribution to inflammatory and hemostatic biomarkers in a stroke population. Additionally, our results suggest shared genetic contributions to circulating CRP levels measured poststroke and risk for incident and recurrent ischemic stroke. These data broaden our understanding of genetic contributors to biomarker variation and ischemic stroke risk, which should be useful in clinical risk evaluation.
Source: Neurology - January 25, 2016 Category: Neurology Authors: Williams, S. R., Hsu, F.-C., Keene, K. L., Chen, W.-M., Nelson, S., Southerland, A. M., Madden, E. B., Coull, B., Gogarten, S. M., Furie, K. L., Dzhivhuho, G., Rowles, J. L., Mehndiratta, P., Malik, R., Dupuis, J., Lin, H., Seshadri, S., Rich, S. S., Sale Tags: All Cerebrovascular disease/Stroke, Case control studies, Risk factors in epidemiology, All Genetics, Association studies in genetics ARTICLE Source Type: research

Ascertainment, classification, and impact of neoplasm detection during prolonged treatment with dual antiplatelet therapy with prasugrel vs. clopidogrel following acute coronary syndrome
Conclusions Neoplasm events were infrequent during long-term DAPT after ACS, were associated with differential cancer-screening practices across regions, and the frequency of neoplasm detection was similar with prasugrel vs. clopidogrel. Trial registration ClinicalTrials.gov identifier: NCT00699998.
Source: European Heart Journal - January 21, 2016 Category: Cardiology Authors: Roe, M. T., Cyr, D. D., Eckart, D., Schulte, P. J., Morse, M. A., Blackwell, K. L., Ready, N. E., Zafar, S. Y., Beaven, A. W., Strickler, J. H., Onken, J. E., Winters, K. J., Houterloot, L., Zamoryakhin, D., Wiviott, S. D., White, H. D., Prabhakaran, D., Tags: Acute coronary syndromes Source Type: research

Combining patient proteomics and in vitro cardiomyocyte phenotype testing to identify potential mediators of heart failure with preserved ejection fraction
Conclusions: Platelets may harbor proteins associated with HFpEF. S100A8 is present in the platelets of subjects with HFpEF and increased in the plasma of the same subjects. We further established a bedside-to-bench translational system that can be utilized as a secondary screen to ascertain whether the biomarkers may be an associated finding or causal to the disease process. S100A8 has been linked with other cardiovascular disease such as atherosclerosis and risk for myocardial infarction, stroke, or death. This is the first report on association of S100A8 with HFpEF.
Source: Journal of Translational Medicine - January 20, 2016 Category: Research Authors: Roseanne RaphaelDiana PurushothamCourtney GastonguayMarla ChesnikWai-Meng KwokHsiang-En WuSanjiv ShahShama MirzaJennifer Strande Source Type: research

The Biggest Medical Stories You May Have Missed In 2015
SPECIAL FROM Next Avenue By Craig Bowron As we head into the New Year, let’s take a look back and see what lessons we should have learned from medical science in 2015. The New England Journal of Medicine’s publication Journal Watch provides physicians and other health care providers with expert analysis of the most recent medical research. Below is a brief synopsis of what the Journal Watch editors felt were the most important stories in general medicine for the year 2015. While you likely heard about a couple, others probably escaped your radar. Getting Aggressive with Strokes We’re familiar with the id...
Source: Science - The Huffington Post - January 15, 2016 Category: Science Source Type: news

Sugary drinks linked to increased fat levels around vital organs
Conclusion This US cohort study found drinking sugar-sweetened beverages on a daily basis is associated with the highest increase in fat accumulation around the abdominal organs, compared with people who do not consume them. But there was an average increase in the amount of this fat in all people who took part in the study, although this was lowest in people who never consumed sugar-sweetened beverages. The study was prospective, which limits some sources of bias, but it has some limitations. For example, the food frequency questionnaire was only conducted once, at baseline. The results are therefore reliant on the p...
Source: NHS News Feed - January 12, 2016 Category: Consumer Health News Tags: Food/diet Diabetes Heart/lungs Obesity Source Type: news

Very Early Carotid Endarterectomy After Intravenous Thrombolysis.
CONCLUSION: This experience suggests that very early CEA after thrombolysis, aimed at removing the source of potential embolisation and restoring blood flow, may be safe and can lead to a favourable outcome. PMID: 26712132 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - December 19, 2015 Category: Surgery Authors: Azzini C, Gentile M, De Vito A, Traina L, Sette E, Fainardi E, Mascoli F, Casetta I Tags: Eur J Vasc Endovasc Surg Source Type: research

Abdominal aortic calcification: a reappraisal of epidemiological and pathophysiological data
In men and women, there is a significant association between the risk of cardiovascular event (myocardial infarction, stroke) and risk of major fragility fracture (hip, vertebra). Abdominal aortic calcification (AAC) can be assessed using semiquantitative scores on spine radiographs and spine scans obtained by DXA. Severe AAC is associated with higher risk of major cardiovascular event. Not only does severe AAC reflect poor cardiovascular health status, but also directly disturbs blood flow in the vascular system.
Source: Bone - December 10, 2015 Category: Orthopaedics Authors: Pawel Szulc Tags: Review Source Type: research

Reversing the effects of the new anti-clotting drugs
The oral anticoagulant warfarin (Coumadin) became available for prescription in 1954. This anti-clotting drug commanded national attention when President Dwight Eisenhower received the drug as part of his treatment following a heart attack. No other oral anticoagulant was successfully developed and marketed in the United States until 2010. Warfarin is a dangerous drug. Along with insulin, it is responsible for the most emergency hospitalizations due to adverse drug reactions. Whereas insulin causes low blood sugar, warfarin is notorious for the complication of major bleeding. Warfarin is plagued by hundreds of drug-drug an...
Source: New Harvard Health Information - December 9, 2015 Category: Consumer Health News Authors: Samuel Z. Goldhaber, MD Tags: Drugs and Supplements Health Heart Health Hypertension and Stroke anti-clotting coumadin deep-vein-thrombosis DVT Source Type: news

What does age-comparative self-rated health measure? A cross-sectional study from the Northern Sweden MONICA Project.
CONCLUSIONS: Emotions and economic satisfaction were associated with comparative self-rated health as well as some medical variables. Utilization of the knowledge of these associations in health care should be further investigated. PMID: 26644159 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Public Health - December 7, 2015 Category: Global & Universal Authors: Waller G, Janlert U, Hamberg K, Forssén A Tags: Scand J Public Health Source Type: research

FDG PET/CT Imaging of Carotid Atherosclerosis
Atherosclerosis is a complex inflammatory process and an integral component of myocardial infarction and stroke. Atherosclerotic plaques can be detected using ultrasonography, myocardial perfusion imaging, coronary angiography, multidetector computed tomography (CT), and MR imaging. These modalities assess the luminal encroachment of the plaques or the structural features. Imaging plaque biology in concert with plaque structure may provide important insights. PET scanning using 18F fluorodeoxyglucose. (18F FDG-PET) is commonly combined with CT scanning to characterize oncological processes. This review examines the role of...
Source: Neuroimaging Clinics - November 25, 2015 Category: Radiology Authors: Abdelrahman Ali, Ahmed Tawakol Source Type: research