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Total 305 results found since Jan 2013.

How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you… Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China. I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1 We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004. Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

Higher versus lower fractions of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit
CONCLUSIONS: In adult ICU patients, it is still not possible to draw clear conclusions about the effects of higher versus lower oxygenation strategies on all-cause mortality, SAEs, quality of life, lung injuries, myocardial infarction, stroke, and sepsis at maximum follow-up. This is due to low or very low-certainty evidence.PMID:37700687 | DOI:10.1002/14651858.CD012631.pub3
Source: Cochrane Database of Systematic Reviews - September 13, 2023 Category: General Medicine Authors: Thomas L Klitgaard Olav L Schj ørring Frederik M Nielsen Christian S Meyhoff Anders Perner J ørn Wetterslev Bodil S Rasmussen Marija Barbateskovic Source Type: research

Finding Power in My Panic Attacks
Trouble started in the form of rivulets of sweat dampening the waistband of my underwear. It was a bluebird afternoon in Phoenix in December of 2020, mid 60s, desert dry, and my heart was jackhammering against my ribcage. Breathing felt like I was sucking air through a stir straw. A small ABC News crew was arrayed before me, ready to broadcast the report I’d written that day, but with my vision narrowed to a needle’s eye, I could barely see them. I tried to swallow away the sandiness in my mouth but realized I’d forgotten how. [time-brightcove not-tgx=”true”] “I can’t swallow!...
Source: TIME: Health - September 12, 2023 Category: Consumer Health News Authors: Matt Gutman Tags: Uncategorized freelance Source Type: news

Carotid total plaque area as an independent predictor of short-term subclinical polyvascular atherosclerosis progression and major adverse cardiac and cerebrovascular events
CONCLUSION: In patients from 40 to 64 years of age with various cardiovascular risks, among the indicators of the cPB, only an increase in cTPA > 42.0 mm2 was shown to be independently associated with an increase in the relative risk (RR) of progression of subclinical polyvascular atherosclerosis by 2.38 (1.08-5.25) times, as well as with the development of MACCE by 3.10 (1.54-6.26) times.PMID:37655749 | DOI:10.1177/17539447231194861
Source: Atherosclerosis - September 1, 2023 Category: Cardiology Authors: Vadim Genkel Alla Kuznetsova Evgeniy Lebedev Alexey Salashenko Albina Savochkina Karina Nikushkina Lubov Pykhova Veronika Sumerkina Igor Shaposhnik Source Type: research

AI-Guided Quantitative Plaque Staging Predicts Long-Term Cardiovascular Outcomes in Patients at Risk for Atherosclerotic CVD
CONCLUSIONS: Through 10-year follow-up, AI-QCT plaque staging showed important prognostic value for MACE and showed additional discriminatory value over clinical risk factors, CACS, and manual guideline-recommended CCTA assessment.PMID:37480907 | DOI:10.1016/j.jcmg.2023.05.020
Source: Atherosclerosis - July 22, 2023 Category: Cardiology Authors: Nick S Nurmohamed Michiel J Bom Ruurt A Jukema Robin J de Groot Roel S Driessen Pepijn A van Diemen Ruben W de Winter Emilie L Gaillard Ralf W Sprengers Erik S G Stroes James K Min James P Earls Rhanderson Cardoso Ron Blankstein Ibrahim Danad Andrew D Cho Source Type: research

Syncope Evaluation: Evidence-Based and Economical
This study eliminated low-risk syncope patients and those with non-syncope transient loss of consciousness, such as seizure and head trauma, using a structured approach in the emergency department (ED), with only high-risk syncope patients being admitted. These high-risk syncope patients made up 28% of the patients included in the study. After admission, a simplified Wells’ pulmonary embolism criteria score was calculated, and a D-dimer was obtained. If either was high, the patient was scanned for PE and 17% were found to be positive, with two-thirds of those being found to have large-vessel pulmonary emboli. The bottom ...
Source: The Hospitalist - July 5, 2023 Category: Hospital Management Authors: Ronda Whitaker Tags: Clinical Guidelines Source Type: research

Association of Arterial Stiffness and Atherosclerotic Burden With Brain Structural Changes Among Japanese Men
Conclusions Among Japanese men, higher arterial stiffness was associated with lower Alzheimer disease signature volumes, whereas higher atherosclerotic burden was associated with brain vascular damage. Arterial stiffness and atherosclerotic burden may be independently associated with brain structural changes via different pathways.PMID:37232267 | DOI:10.1161/JAHA.122.028586
Source: Atherosclerosis - May 26, 2023 Category: Cardiology Authors: Nazar M Azahar Yuichiro Yano Aya Kadota Akihiko Shiino Ali H Syaifullah Naoko Miyagawa Keiko Kondo Mohammad Moniruzzaman Sayuki Torii Hiroyoshi Segawa Takashi Hisamatsu Akira Fujiyoshi Kazuhiko Nozaki Ikuo Tooyama Hirotsugu Ueshima Katsuyuki Miura SESSA R Source Type: research

Tumor Genomic Profile Is Associated With Arterial Thromboembolism Risk in  Patients With Solid Cancer
CONCLUSIONS: In a large genomic tumor-profiling registry of patients with solid cancers, alterations in KRAS and STK11 were associated with an increased risk for ATE independent of cancer type. Further investigation is needed to elucidate the mechanism by which these mutations contribute to ATE in this high-risk population.PMID:37144118 | PMC:PMC10152200 | DOI:10.1016/j.jaccao.2023.01.009
Source: Cancer Control - May 5, 2023 Category: Cancer & Oncology Authors: Stephanie Feldman Dipti Gupta Babak B Navi Ka-Wai Grace Ho Peter Willeit Sean Devlin Kelly L Bolton Maria E Arcila Simon Mantha Source Type: research

Inflammation May Be the Culprit Behind Our Deadliest Diseases
In the early days of my medical residency, I met a man whom we’ll call Jason. He arrived to our emergency room on a holiday, nonchalant yet amiable, and complained of mild chest pain. Jason was tall and trim, with a strong South Boston accent and fingertips still faintly stained from his last home-improvement project. He was only 45 years old, but he looked much younger. He didn’t smoke, barely drank alcohol, and his cholesterol levels had always been normal. No one in his family had a history of heart disease. He asked us if we could work quickly—he wanted to be home for dinner with his daughters. [time-...
Source: TIME: Health - April 11, 2023 Category: Consumer Health News Authors: Shilpa Ravella Tags: Uncategorized freelance health Source Type: news

Deep-Learning for Epicardial Adipose Tissue Assessment With Computed  Tomography: Implications for Cardiovascular Risk Prediction
CONCLUSIONS: Automated assessment of EAT volume is possible in CCTA, including in patients who are technically challenging; it forms a powerful marker of metabolically unhealthy visceral obesity, which could be used for cardiovascular risk stratification.PMID:36881425 | DOI:10.1016/j.jcmg.2022.11.018
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Henry W West Muhammad Siddique Michelle C Williams Lucrezia Volpe Ria Desai Maria Lyasheva Sheena Thomas Katerina Dangas Christos P Kotanidis Pete Tomlins Ciara Mahon Attila Kardos David Adlam John Graby Jonathan C L Rodrigues Cheerag Shirodaria John Dean Source Type: research

An unusual case of takayasu arteritis presenting as acute myocardial infarction and ischaemic stroke
CONCLUSION: This disease should be considered in female patients who present with chronic inflammation and acute coronary syndrome.PMID:36791035 | PMC:PMC9766845 | DOI:10.36141/svdld.v39i3.12688
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - February 15, 2023 Category: Respiratory Medicine Authors: Sonja Golubovi ć Mia Manojlovi ć Tatjana Ili ć Filip Samardzi ć Biljana Vu čković Dragana Tomi ć-Naglić Ivana Bajkin Sla đana Pejaković Source Type: research