Tumor Genomic Profile Is Associated With Arterial Thromboembolism Risk in  Patients With Solid Cancer

CONCLUSIONS: In a large genomic tumor-profiling registry of patients with solid cancers, alterations in KRAS and STK11 were associated with an increased risk for ATE independent of cancer type. Further investigation is needed to elucidate the mechanism by which these mutations contribute to ATE in this high-risk population.PMID:37144118 | PMC:PMC10152200 | DOI:10.1016/j.jaccao.2023.01.009

Source: Cancer Control - May 5, 2023 Category: Cancer & Oncology Authors: Stephanie Feldman Dipti Gupta Babak B Navi Ka-Wai Grace Ho Peter Willeit Sean Devlin Kelly L Bolton Maria E Arcila Simon Mantha Source Type: research