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Nitrous oxide-based techniques versus nitrous oxide-free techniques for general anaesthesia.
CONCLUSIONS: Given the evidence from this Cochrane review, the avoidance of nitrous oxide may be reasonable in participants with pre-existing poor pulmonary function or at high risk of postoperative nausea and vomiting. Since there are eight studies awaiting classification, selection bias may exist in our systematic review. PMID: 26545294 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - November 6, 2015 Category: Journals (General) Authors: Sun R, Jia WQ, Zhang P, Yang K, Tian JH, Ma B, Liu Y, Jia RH, Luo XF, Kuriyama A Tags: Cochrane Database Syst Rev Source Type: research

Long-Term Exposure to Ambient Fine Particulate Matter and Renal Function in Older Men: The Veterans Administration Normative Aging Study
Conclusions: In this longitudinal sample of older men, the findings supported the hypothesis that long-term PM2.5 exposure negatively affects renal function and increases renal function decline. Citation: Mehta AJ, Zanobetti A, Bind MC, Kloog I, Koutrakis P, Sparrow D, Vokonas PS, Schwartz JD. 2016. Long-term exposure to ambient fine particulate matter and renal function in older men: the VA Normative Aging Study. Environ Health Perspect 124:1353–1360; http://dx.doi.org/10.1289/ehp.1510269 Address correspondence to A.J. Mehta, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Landmark Ce...
Source: EHP Research - September 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article September 2016 Source Type: research

Cardiopulmonary factors affecting 6-min walk distance in patients with idiopathic inflammatory myopathies
In conclusion, impaired DLCO due to interstitial lung disease was suggested to be a fundamental parameter affecting exercise capacity, in addition to heart involvement, in patients with idiopathic inflammatory myopathies.
Source: Rheumatology International - May 14, 2018 Category: Rheumatology Source Type: research

‘A clear case of chronic aspiration of starch (potato)’
In June 2011 a 74 years old‐non smoker woman came to our attention complaining for months dyspnea and dry cough resistant to nonspecific antibiotic therapy (amoxicillin/clavulanic acid and levofloxacin, prescribed by her physician, for 10 days). She had no history of respiratory diseases; she had instead history of cerebri stroke (in March 2006), without neurological outcome, and throat cancer treated with radiotherapy 10 years before. When she came to our attention, physical examination showed dry crackles bilaterally in the lower lung fields. Pulmonary function test showed a mild restrictive respiratory pattern while t...
Source: The Clinical Respiratory Journal - April 11, 2013 Category: Respiratory Medicine Authors: A. Andreani, G. Cappiello, M. Valli, E. Businarolo, R. Melara, M. Giovannini, G. Rossi Tags: Forum Source Type: research

Arrhythmia and exercise intolerance in Fontan patients: Current status and future burden
Conclusions: The prevalence of clinically relevant arrhythmia and severe exercise intolerance increased significantly with age in Danish Fontan patients. The future Fontan burden was estimated showing an increase in the prevalence of older patients, clinically relevant arrhythmia, and severe exercise intolerance.
Source: International Journal of Cardiology - January 21, 2013 Category: Cardiology Authors: L. Idorn, K. Juul, A.S. Jensen, B. Hanel, K.G. Nielsen, H. Andersen, J.I. Reimers, K.E. Sørensen, L. Søndergaard Tags: Original Articles Source Type: research

C-reactive protein: Its correlations with pulmonary function, physical capacity and anthropometric measurements in patients with metabolic syndrome
Conclusions: It was found negative relationships between CRP level with PF and PC. On the contrary, there were positive correlations of CRP with parameters of BC. We think that it can be provided decline in the CRP level and increment in PF improving the functional capacity and body composition with aerobic exercise in patients with MS.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Demirtas, R. N., Bozdemir Ozel, C., Arikan, H., Calik-Kutukcu, E., Saglam, M., Vardar-Yagli, N., Celer, O., Akalin, A., Alatas, F. Tags: 9.2 Physiotherapists Source Type: research

Impaired Pulmonary Diffusion in Heart Failure With Preserved Ejection Fraction
Conclusions Subjects with HFpEF display altered pulmonary function and gas exchange at rest and especially during exercise, which contributes to exercise intolerance. Novel therapies that improve gas diffusion may be effective to improve exercise tolerance in patients with HFpEF.
Source: JACC: Heart Failure - May 30, 2016 Category: Cardiology Source Type: research

Restrictive Spirometry Pattern is Associated with Increased Arterial Stiffness in Men and Women.
CONCLUSIONS: Both restrictive spirometry pattern and reduced FVC were associated with a higher risk of arterial stiffness, not only in males but also in females. Clinically, assessment of arterial stiffness might be considered in individuals with restrictive spirometry pattern. PMID: 28411113 [PubMed - as supplied by publisher]
Source: Chest - April 11, 2017 Category: Respiratory Medicine Authors: Wu IH, Sun ZJ, Lu FH, Yang YC, Chou CY, Chang CJ, Wu JS Tags: Chest Source Type: research

Cardiovascular comorbidity in Danish patients with scleroderma-associated interstitial lung disease
Conclusion: CC was frequent among patients with SSc-ILD but was not associated with increased mortality. As expected, PH was associated with severe excess mortality.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Madsen, G. A., Hyldgaard, C., Bendstrup, E. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Change in pulmonary function and cardiorespiratory fitness following chemotherapy in testicular cancer patients - a pilot study
Conclusions: There was a substantial reduction in VO2max after BEP corresponding to three decades of physiological aging. This reduction may reflect a decrease in the patients’ cardiac function and oxygen carrying capacity, and not to reduced DLco.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Edvardsen, E., Larsen, K.-O., Fossa, S. D., Ikdahl, T., Loge, J. H., Thorsen, L. Tags: Clinical Respiratory Physiology, Exercise and Functional Imaging Source Type: research

Mortality causes in patients with advanced lung disease in long term oxygen therapy
Conclusion: Patients presented exacerbations of respiratory diseases as the main causes of mortality and with a very low survival time rate.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Oliveira, V., Bastos, T. M. L. C., Taliberti, I. B., Rodrigues, T. S. C., Silva, R. S., Goulart Filho, L. R., Cunha, T. M., Damian, M. G. C., Gomes, M. A. G. Tags: Clinical Problems Source Type: research

Compensation of Respiratory-Related Postural Perturbation Is Achieved by Maintenance of Head-to-Pelvis Alignment in Healthy Humans
Conclusion Extreme lung volume variations over vital capacity is associated with changes of thoracic curvature bringing it outside the normal range, which would theoretically compromise verticality. This is however fully compensated by adaptations of the cervical curvature and pelvic tilt to preserve adequate head-to-pelvis verticality and horizontal gaze alignment. Lung volume related postural perturbations increase with age, but age did not affect head-to-pelvis alignment. Future studies are needed to investigate potential postural dysfunction in chronic respiratory diseases that induce changes of lung volume or chest g...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Cardiopulmonary Capacity in Children During Exercise Testing: The Differences Between Treadmill and Upright and Supine Cycle Ergometry
Conclusion: There are no differences in peak cardiac output between the upright bicycle test and supine bicycle tests. Heart rate and corrected peak V.O2 are lower in the supine test (0°) than the upright bicycle test. In the treadmill test, it is a higher absolute and relative peak V.O2. Despite the latter differences, we are convinced that both upright and supine bicycle tests are apt in the clinical setting when needed.
Source: Frontiers in Physiology - November 28, 2019 Category: Physiology Source Type: research

Breast cancer survivors with preserved or rescued cardiorespiratory fitness have similar cardiac, pulmonary and muscle function compared to controls
AbstractBreast cancer survivors (BCS) have a high prevalence of cardiovascular disease and low cardiorespiratory fitness (CRF). CRF is an important predictor of survival in BCS. However, the physiological factors that contribute to low CRF in BCS have not been completely elucidated. To assess differences in physiological factors (cardiac, pulmonary, muscle function) related to CRF between BCS and controls. Twenty-three BCS and 23 age-body mass index (BMI) matched controls underwent a peak cycling exercise test to determine CRF, with physiological factors measured at resting and at peak exercise. Cardiac hemodynamics (strok...
Source: European Journal of Applied Physiology - July 7, 2022 Category: Physiology Source Type: research

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