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Total 11289 results found since Jan 2013.

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in patients with stroke or transient ischaemic attack.
CONCLUSIONS: PPAR-γ agonists were demonstrated to reduce recurrent stroke and total events of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke, and improve insulin sensitivity and the stabilisation of carotid plaques. There is evidence of limited quality that they are well-tolerated. However, the conclusions should be interpreted with caution considering the small number and the quality of the included studies. In future, well-designed, double-blind RCTs with large samples are required to test the efficacy and safety of PPAR-γ agonists in the secondary prevention of stroke and related vascular ev...
Source: Cochrane Database of Systematic Reviews - January 8, 2014 Category: Journals (General) Authors: Liu J, Wang LN Tags: Cochrane Database Syst Rev Source Type: research

Randomized clinical trial of the timing it right stroke family support program: research protocol
The objective of this multi-site randomized controlled trial is to determine if delivering the TIRSFSP across the stroke care continuum improves caregivers' sense of being supported and emotional well-being. Methods: Our multi-site single-blinded randomized controlled trial will recruit 300 family caregivers of stroke survivors from urban and rural acute care hospitals. After completing a baseline assessment, participants will be randomly allocated to one of three groups: 1) TIRSFSP guided by a stroke support person (health care professional with stroke care experience), delivered in-person during acute care and by telepho...
Source: BMC Health Services Research - January 17, 2014 Category: Journals (General) Authors: Jill CameronGary NaglieMonique GignacMark BayleyGrace WarnerTheresa GreenAnna CzerwonkaMaria HuijbregtsFrank SilverSteve PhillipsAngela Cheung Source Type: research

Mechanisms of early and delayed stroke after systematic off-pump coronary artery bypass.
CONCLUSION: The incidence of stroke after systematic OPCAB was low. Early and delayed strokes were equally distributed. Stroke mechanisms were predominantly embolic. Early and delayed stroke differed in their mechanisms. Early and delayed stroke should be considered as two separate entities and different preventive strategies should be applied in future intervention. PMID: 24560991 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - February 20, 2014 Category: Journals (General) Authors: Chen JW, Lin CH, Hsu RB Tags: J Formos Med Assoc Source Type: research

Tailored approaches to stroke health education (TASHE): study protocol for a randomized controlled trial
DiscussionThis is the first randomized trial of a church-placed narrative intervention to improve stroke outcomes in urban Black and Hispanic populations. A film intervention has the potential to make a significant public health impact, as film is a highly scalable and disseminable medium. Since there is at least one church in almost every neighborhood in the USA, churches have the ability and reach to play an important role in the dissemination and translation of stroke prevention programs in minority communities.Trial registrationNCT01909271; July 22, 2013
Source: Trials - April 19, 2015 Category: Journals (General) Authors: Joseph RavenellEllyn Leighton-HerrmannAmparo Abel-BeyAlexandra DeSorboJeanne TeresiLenfis ValdezMadeleine GordilloWilliam GerinMichael HechtMildred RamirezJames NobleElizabeth CohnGiardin Jean-LouisTanya SpruillSalina WaddyGbenga OgedegbeOlajide Williams Source Type: research

Closure versus medical therapy for preventing recurrent stroke in patients with patent foramen ovale and a history of cryptogenic stroke or transient ischemic attack.
CONCLUSIONS: The combined data from recent RCTs have shown no statistically significant differences between TDC and medical therapy in the prevention of recurrent ischemic stroke. TDC closure was associated with an increased risk of atrial fibrillation but not with serious adverse events. PMID: 26346232 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - September 8, 2015 Category: Journals (General) Authors: Li J, Liu J, Liu M, Zhang S, Hao Z, Zhang J, Zhang C Tags: Cochrane Database Syst Rev Source Type: research

Mechanisms of early and delayed stroke after systematic off-pump coronary artery bypass
Conclusion The incidence of stroke after systematic OPCAB was low. Early and delayed strokes were equally distributed. Stroke mechanisms were predominantly embolic. Early and delayed stroke differed in their mechanisms. Early and delayed stroke should be considered as two separate entities and different preventive strategies should be applied in future intervention.
Source: Journal of the Formosan Medical Association - September 27, 2015 Category: Journals (General) Source Type: research

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in patients with stroke or transient ischaemic attack.
CONCLUSIONS: PPAR-γ agonists appear to reduce recurrent stroke and total events of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke, and improve insulin sensitivity and the stabilisation of carotid plaques. There is evidence of limited quality that they are well tolerated. However, the conclusions should be interpreted with caution considering the small number and the quality of the included studies. In future, well-designed, double-blind RCTs with large samples are required to assess the efficacy and safety of PPAR-γ agonists in the secondary prevention of stroke and related vascular events in p...
Source: Cochrane Database of Systematic Reviews - October 29, 2015 Category: Journals (General) Authors: Liu J, Wang LN Tags: Cochrane Database Syst Rev Source Type: research

Association of Atrial Fibrillation and Stroke: Analysis of Maccabi Health Services Cardiovascular Database.
CONCLUSIONS: Analysis of the MHS vascular database yielded useful information on stroke prevalence and association of known risk factors with stroke, which is consistent with the epidemiological literature elsewhere. Further analysis of health fund data could potentially provide useful information in the future. PMID: 26394490 [PubMed - in process]
Source: The Israel Medical Association Journal - November 18, 2015 Category: Journals (General) Tags: Isr Med Assoc J Source Type: research

Barriers and facilitators to staying in work after stroke: insight from an online forum
Conclusions Despite having been able to return to work after a stroke, people may still experience difficulties in staying in work and risking losing their job. There is a need to improve awareness, in particular of invisible stroke-related impairments, among stroke survivors, work personnel and clinicians. This might be achieved through improved assessments of residual impairments in the workplace and in general practice. Future studies should investigate the effect of unrecognised fatigue and invisible impairments on staying in work following stroke, and explore the potential role for primary care in supporting stroke su...
Source: BMJ Open - April 5, 2016 Category: Journals (General) Authors: Balasooriya-Smeekens, C., Bateman, A., Mant, J., De Simoni, A. Tags: Open access, Cardiovascular medicine, General practice / Family practice, Occupational and environmental medicine, Qualitative research, Rehabilitation medicine, Research methods Source Type: research

Cardiovascular diseases in patients 65 years and younger with non-cardiogenic stroke.
CONCLUSIONS: Aetiologically heterogeneous stroke and cardiogenic stroke are the most commonly observed among young stroke patients. Cardiomyopathy and atrial fibrillation are the most common sources of cerebral embolism in young patients with cardiogenic stroke. Nearly 1/5 of patients with a non-cardiogenic stroke have congenital or acquired structural changes in the heart. PMID: 27279848 [PubMed]
Source: Archives of Medical Science - June 10, 2016 Category: Journals (General) Tags: Arch Med Sci Source Type: research

Improvement of survival in Polish stroke patients is related to reduced stroke severity and better control of risk factors: the Krakow Stroke Database.
CONCLUSIONS: Reduced stroke severity is associated with better recognition and control of risk factors and explains the improvement of survival in Polish stroke patients. PMID: 27279847 [PubMed]
Source: Archives of Medical Science - June 10, 2016 Category: Journals (General) Tags: Arch Med Sci Source Type: research

Exploring stroke survivors' and physiotherapists' views of self-management after stroke: a qualitative study in the UK
Conclusions If self-management support approaches are to be used, further work is required to explore the language and strategies used by professionals to support self-management, and the barriers to supporting self-management at different time points after stroke.
Source: BMJ Open - March 9, 2017 Category: Journals (General) Authors: Sadler, E., Wolfe, C. D. A., Jones, F., McKevitt, C. Tags: Open access, Health services research, Qualitative research Source Type: research

The effect of statins on National Institutes of Health Stroke Scale (NiHSS) in Ischemic stroke.
Conclusion. According to the findings of this research, taking statins before the onset of stroke and immediately after it showed no significant difference in the level of following dysfunction, measured with NIHSS, and further studies are necessary. PMID: 28316706 [PubMed]
Source: Journal of Medicine and Life - March 23, 2017 Category: Journals (General) Tags: J Med Life Source Type: research

Clinical role of von Willebrand factor in acute ischemic stroke.
CONCLUSION: Among the patients with ischemic stroke, levels of VWF were not increased in those with CE stroke. High levels of VWF were associated with greater severity of stroke as well as with poor clinical outcome. PMID: 28409234 [PubMed - as supplied by publisher]
Source: Wiener Klinische Wochenschrift - April 13, 2017 Category: Journals (General) Authors: Menih M, Križmarić M, Hojs Fabjan T Tags: Wien Klin Wochenschr Source Type: research

Stroke Hospital Characteristics in the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities Study.
CONCLUSIONS: Results from our survey indicated variability in hospital- and system-level characteristics in stroke care across hospitals in Florida and Puerto Rico. Identification of these variations, which may explain potential disparities, can help clinicians understand gaps in stroke care and outcomes and targeted interventions to reduce identified disparities can be implemented. PMID: 28679016 [PubMed - in process]
Source: Southern Medical Journal - July 6, 2017 Category: General Medicine Tags: South Med J Source Type: research