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Specialty: Hematology
Condition: Heart Attack

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Total 519 results found since Jan 2013.

Non-vitamin K Antagonist Oral Anticoagulant, Warfarin, and ABC Pathway Adherence on Hierarchical Outcomes: Win Ratio Analysis of the COOL-AF Registry
CONCLUSION: This Win Ratio analysis demonstrates the significant benefits of NOACs over warfarin and ABC pathway adherence over nonadherence in reducing the composite outcome in patients with AF.PMID:37625457 | DOI:10.1055/s-0043-1772773
Source: Thrombosis and Haemostasis - August 25, 2023 Category: Hematology Authors: Sukrit Treewaree Gregory Y H Lip Rungroj Krittayaphong Source Type: research

Reticulated Platelets Predict Cardiovascular Death and Adverse Events in Coronary Artery Disease: A Systematic Review and Meta-analysis
CONCLUSION: Elevated RPs are significantly associated with increased risk of cardiovascular events and cardiovascular death.PMID:37696301 | DOI:10.1055/s-0043-1773763
Source: Thrombosis and Haemostasis - September 11, 2023 Category: Hematology Authors: Dario Bongiovanni Laura Novelli Francesco Condello Kilian Kirmes Jiaying Han Bastian Wein S ébastien Elvinger Giacomo Viggiani Moritz von Scheidt Karl-Ludwig Laugwitz Philip W J Raake Adnan Kastrati Mauro Chiarito Isabell Bernlochner Source Type: research

Occurrence of thrombosis in congenital thrombocytopenic disorders: a critical annotation of the literature
Patients with a low platelet count are prone to bleeding. The occurrence of a thrombotic event in congenital thrombocytopenic patients is rare and puzzling. At least nine patients with Glanzmann thrombasthenia have been reported to have had a thrombotic event, eight venous and one arterial (intracardiac, in the left ventricle). On the contrary, three patients with Bernard–Soulier syndrome have been shown to have had arterial thrombosis (myocardial infarction) but no venous thrombosis. Finally, seven patients with the familiar macrothrombocytopenia due to alterations of the MYH9 gene have been reported to have had thrombo...
Source: Blood Coagulation and Fibrinolysis - January 1, 2013 Category: Hematology Tags: Original Articles Source Type: research

Acute Promyelocytic Leukemia-Associated Thrombosis.
Abstract Patients with acute promyelocytic leukemia (APL) are prone to both bleeding and thrombosis. The bleeding complications are well known. In contrast, APL-associated thrombosis is relatively underappreciated. We aimed to explore the issue of APL-associated thrombosis events. In the past 20 years, 127 cases with APL were found in our hospital database. We collected their coagulation laboratory profiles, including leukemia burdens, white blood cell and platelet counts, prothrombin time, activated partial thromboplastin time, fibrinogen levels, and disseminated intravascular coagulation scores. Data were compar...
Source: Acta Haematologica - January 23, 2013 Category: Hematology Authors: Chang H, Kuo MC, Shih LY, Wu JH, Lin TL, Dunn P, Tang TC, Hung YS, Wang PN Tags: Acta Haematol Source Type: research

Cardiovascular mortality due to pulmonary embolism in subjects with renal impairment: patients’ comorbidities are crucial
Abstract we read with great interest the paper by Ocak et al. (1). The authors found that the age‐ and sex‐standardized mortality rate (SMR) for pulmonary embolism (PE) was 12.2 (95% CI 10.2‐14.6) times higher in dialysis patients than in the general population. Such SMR was even higher than that of myocardial infarction (MI) (11.0, 95% CI 10.6‐11.4), stroke (8.4 (95% CI 8.0‐8.8), and other cardiovascular disease (8.3, 95% CI 8.0‐8.5) On the one hand, the association between the different grade of impaired renal function and MI received important confirmation (2), and also a recent study from our group conducte...
Source: Journal of Thrombosis and Haemostasis - April 4, 2013 Category: Hematology Authors: Fabio Fabbian, Francesco Dentali, Walter Ageno, Roberto Manfredini Tags: Letter Rebuttal Source Type: research

Remote ischemic preconditioning reduces thrombus formation in the rat
Ischemic preconditioning (IPC) is known to protect tissue from ischemia and has effect both locally[i] and systemically[ii]. Remote IPC (RIPC) induced by limb ischemia provides systemic protection against prolonged ischemia in the target organ. RIPC has been reported to reduce infarct size in patients with ST‐elevation myocardial infarction (STEMI) undergoing primary angioplasty[iii] and is currently evaluated in patients with ischemic stroke undergoing thrombolysis (NCT00975962). © 2013 International Society on Thrombosis and Haemostasis
Source: Journal of Thrombosis and Haemostasis - March 18, 2013 Category: Hematology Authors: DM Røpcke, VE Hjortdal, GE Toft, MO Jensen, SD Kristensen Tags: Letter ‐ to the Editor Source Type: research

Blood Pressure Recordings During Hemodialysis Access Interventions: Implications for Acute Management
Abstract A retrospective study evaluating the pattern of blood pressure and its related complications before, during, and after percutaneous hemodialysis interventions was performed in patients presenting with asymptomatic hypertension. Hemodialysis patients undergoing percutaneous interventions including tunneled hemodialysis catheter insertion, percutaneous balloon angioplasty and thrombectomy procedure, and stage II hypertension (systolic blood pressure ≥160 mmHg) were included in this analysis. Blood pressure medications were not used while midazolam and fentanyl were routinely administered. Patients were followed f...
Source: Seminars In Dialysis - March 28, 2013 Category: Hematology Authors: Arif Asif, Hector Castro, Ahmed Ameen Waheed, Vishesh Kumar, Syed S Haqqie, Gary Siskin, Roy O Mathew, Darius Mason, Tushar Vachharajani, Ali Nayer, Donna Merrill, Muhammad UT Akmal, Loay Salman Tags: Investigation Source Type: research

Seek and You Shall Find—But Then What Do You Do? Cold Agglutinins in Cardiopulmonary Bypass and a Single-Center Experience With Cold Agglutinin Screening Before Cardiac Surgery
Abstract: Cardiopulmonary bypass (CPB) during cardiac surgery can involve deliberate hypothermia of the systemic (22-36°C) and coronary circulations (as low as 8-12°C). Adverse sequelae of cold-active antibodies have been feared and reported under such conditions, and some centers thus elect to screen for cold agglutinins before CPB. We reviewed the literature on cold agglutinins in cardiac surgery and described the yields and effects of cold agglutinin screening (CAS) in 14900 cardiac surgery patients undergoing CPB over 8 years at a single institution. Cold agglutinin screening was positive in 47 cases (0.3%), at an an...
Source: Transfusion Medicine Reviews - February 4, 2013 Category: Hematology Authors: Michael D. Jain, Rosa Cabrerizo-Sanchez, Keyvan Karkouti, Terrence Yau, Jacob M. Pendergrast, Christine M. Cserti-Gazdewich Tags: Original Articles Source Type: research

Bleeding risks associated with vitamin K antagonists
Abstract: Vitamin K antagonists are widely used for the prevention of stroke due to atrial fibrillation, treatment and secondary prevention of venous thromboembolism, prevention of valvular thromboembolism in patients with prosthetic heart valves, and secondary prevention of acute myocardial infarction. The most common adverse event experienced by patients receiving anticoagulant therapy is major bleeding. The incidence of major bleeding in patients receiving long-term anticoagulation with a vitamin K antagonist in contemporary studies is 1–3% per year. To determine if the benefits of anticoagulant therapy outweigh the r...
Source: Blood Reviews - March 11, 2013 Category: Hematology Authors: Lori-Ann Linkins Source Type: research

A low-volume, single pass in-vitro system of high shear thrombosis in a stenosis
Conclusions: Occlusive thrombus blocks the collagen-coated lumen with millions of platelets using human whole, heparinized blood. Rapid Platelet Accumulation rates in human blood are 4.5±2.4μm3/μm2/min (n=21). There is an initial lag time of 7.4±3.8min (n=21) before the onset of large scale thrombosis. The rates of platelet accumulation in vitro are consistent with the clinical timescale of coronary or carotid artery occlusion. Porcine blood has a faster accumulation rate of 9.6±6.1μm3/μm2/min (n=7, p
Source: Thrombosis Research - March 27, 2013 Category: Hematology Authors: Andrea N. Para, David N. Ku Tags: Coagulation and Fibrinolysis Source Type: research

Increased risk of CVD after VT is determined by common etiologic factors
In conclusion, individuals with VT had an increased risk of CVD. This could be explained by common etiologic factors.
Source: Blood - June 13, 2013 Category: Hematology Authors: Roach, R. E. J., Lijfering, W. M., Flinterman, L. E., Rosendaal, F. R., Cannegieter, S. C. Tags: Free Research Articles, Thrombosis and Hemostasis Source Type: research

A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia.
CONCLUSION: Two 750-mg FCM infusions are safe and superior to oral iron in increasing Hb levels in IDA patients with inadequate oral iron response. PMID: 23772856 [PubMed - as supplied by publisher]
Source: Transfusion - June 17, 2013 Category: Hematology Authors: Onken JE, Bregman DB, Harrington RA, Morris D, Acs P, Akright B, Barish C, Bhaskar BS, Smith-Nguyen GN, Butcher A, Koch TA, Goodnough LT Tags: Transfusion Source Type: research

MRI artifacts in the ferric chloride thrombus animal model: an alternative solution
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 29, 2013 Category: Hematology Authors: Martijn Wolters, Raf H.M. Hoof, A. Wagenaar, Kim Douma, Marc A.M.J. Zandvoort, Tilman H. Hackeng, Mark J. Post, Walter H. Backes, M. Eline Kooi Tags: Letter ‐ to the Editor Source Type: research

Impact of Altitude on Predicting Midterm Outcome in Patients With ST Elevation Myocardial Infarction
In conclusion, altitude status and altitude-related hematologic changes had no influence over the mid-term outcomes in STEMI patients treated with percutaneous intervention.
Source: Clinical and Applied Thrombosis/Hemostasis - July 3, 2013 Category: Hematology Authors: Isik, T., Tanboga, I. H., Ayhan, E., Uyarel, H., Kaya, A., Kurt, M., Erdogan, E., Ergelen, M., Cicek, G., Akgul, O., Ghannadian, B. Tags: Original Articles Source Type: research

Time trends in pulmonary embolism: A matter of age and gender
Venous thromboembolism (VTE) is the third most common cardiovascular disease . Pulmonary embolism (PE) is potentially lethal and is the most serious manifestation of VTE . Notably, PE is the leading preventable cause of death in hospitalized patients , and is the third most common cardiovascular cause of death after myocardial infarction and stroke in Western world . Risk factors for VTE and PE include old age, surgery, immobilization, trauma, fractures, cancer, pregnancy, puerperium, oral contraceptive pill (OCP) use, and hormone replacement therapy (HRT) . Genetic factors are also important in VTE risk and family history...
Source: Thrombosis Research - June 24, 2013 Category: Hematology Authors: Bengt Zöller Tags: Editorials Source Type: research