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Condition: Hemorrhagic Stroke
Procedure: SPECT

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Total 26 results found since Jan 2013.

Design of Randomized, double‐blind, Evaluation in secondary Stroke Prevention comparing the EfficaCy and safety of the oral Thrombin inhibitor dabigatran etexilate vs. acetylsalicylic acid in patients with Embolic Stroke of Undetermined Source (RE‐SPECT ESUS)
DiscussionAcetylsalicylic acid is the most common antithrombotic given to patients with embolic strokes of undetermined source to reduce recurrence risk. This trial will determine whether anticoagulation with dabigatran is more effective than acetylsalicylic acid, and acceptably safe.
Source: International Journal of Stroke - September 30, 2015 Category: Neurology Authors: Hans‐Christoph Diener, J. Donald Easton, Christopher B. Granger, Lisa Cronin, Christine Duffy, Daniel Cotton, Martina Brueckmann, Ralph L. Sacco, Tags: Protocol Source Type: research

Design of Randomized, double ‐blind, Evaluation in secondary Stroke Prevention comparing the EfficaCy and safety of the oral Thrombin inhibitor dabigatran etexilate vs. acetylsalicylic acid in patients with Embolic Stroke of Undetermined Source (RE‐SPECT ESUS)
DiscussionAcetylsalicylic acid is the most common antithrombotic given to patients with embolic strokes of undetermined source to reduce recurrence risk. This trial will determine whether anticoagulation with dabigatran is more effective than acetylsalicylic acid, and acceptably safe.
Source: International Journal of Stroke - September 29, 2015 Category: Neurology Authors: Hans ‐Christoph Diener, J. Donald Easton, Christopher B. Granger, Lisa Cronin, Christine Duffy, Daniel Cotton, Martina Brueckmann, Ralph L. Sacco, Tags: Protocol Source Type: research

Intravenous Thrombolysis Resulting In Acute Ischemic Stroke Recanalization Can Lead To Cerebral Hyperperfusion Syndrome (P7.123)
Conclusion- Cerebral hyperperfusion syndrome after intravenous thrombolysis in acute ischemic stroke should be suspected in patients that achieve arterial recanalization and develop unexplained new neuropsychiatric manifestations.Disclosure: Dr. Ong has nothing to disclose. Dr. Yeo has nothing to disclose. Dr. Ting has nothing to disclose. Dr. Sinha has nothing to disclose. Dr. Teoh has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Seet has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ong, J., Yeo, L., Ting, E., Sinha, A., Teoh, H. L., Chan, B., Seet, C. S., Sharma, V. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment Source Type: research

Ischemic Conditioning Is Safe and Effective for Octo- and Nonagenarians in Stroke Prevention and Treatment
The objective of this study was to evaluate the safety and effectiveness of BAIPC in reducing stroke recurrence in octo- and nonagenarian patients with SIAS. Fifty-eight patients with SIAS were enrolled in this randomized controlled prospective study for 180 consecutive days. All patients enrolled in the study received standard medical management. Patients in the BAIPC group (n = 30) underwent 5 cycles consisting of bilateral arm ischemia followed by reperfusion for 5 min each twice daily. Those in the control group (n = 28) underwent sham-BAIPC twice daily. Blood pressure, heart rate, local skin status, plasma m...
Source: Neurotherapeutics - May 9, 2015 Category: Neurology Source Type: research

Posterior Fossa Syndrome After Cerebellar Stroke.
We report longitudinal clinical, neurocognitive and neuroradiological findings in a 71-year-old right-handed patient who developed PFS following a right cerebellar haemorrhage that was not surgically evacuated. During follow-up, functional neuroimaging was conducted by means of quantified Tc-99m-ECD SPECT studies. After a 10-day period of akinetic mutism, the clinical picture developed into cerebellar cognitive affective syndrome (CCAS) with reversion to a previously learnt accent, consistent with neurogenic foreign accent syndrome (FAS). No psychometric evidence for dementia was found. Quantified Tc-99m-ECD SPECT studies ...
Source: Cerebellum - April 11, 2013 Category: Neuroscience Authors: Mariën P, Verslegers L, Moens M, Dua G, Herregods P, Verhoeven J Tags: Cerebellum Source Type: research

Impact of cortical hemodynamic failure on both subsequent hemorrhagic stroke and effect of bypass surgery in hemorrhagic moyamoya disease: a supplementary analysis of the Japan Adult Moyamoya Trial.
CONCLUSIONS: Hemodynamic failure is an independent risk factor for subsequent hemorrhage in hemorrhagic moyamoya disease. Direct bypass surgery showed a significant preventive effect in the hemodynamically impaired hemispheres. Thus, hemodynamic failure, as well as previously proposed factors such as choroidal anastomosis, should be considered for the surgical indication in hemorrhagic moyamoya disease.Clinical trial registration no.: C000000166 (umin.ac.jp). PMID: 32168484 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - March 12, 2020 Category: Neurosurgery Authors: Takahashi JC, Funaki T, Houkin K, Kuroda S, Fujimura M, Tomata Y, Miyamoto S Tags: J Neurosurg Source Type: research

Preoperatively estimated graft flow rate contributes to the improvement of hemodynamics in revascularization for Moyamoya disease
Moyamoya disease is a cerebrovascular disease that is characterized by chronic progressive stenosis of the terminal portion of the internal carotid artery (ICA) on both sides of the brain, which results in an abnormal vascular network of the collateral pathways at the base of the brain.1,2 Therefore, patients with Moyamoya disease have a decreased cerebral blood flow (CBF) and reduced cerebral perfusion pressure,3 which can result in ischemic and/or hemorrhagic stroke. This hemodynamic condition can be evaluated using positron emission tomography (PET) or single-photon emission computed tomography (SPECT) as the gold standard procedure.
Source: Journal of Stroke and Cerebrovascular Diseases - November 7, 2020 Category: Neurology Authors: Tomoyoshi Kuribara, Takeshi Mikami, Katsuya Komatsu, Yusuke Kimura, Sangnyon Kim, Kei Miyata, Yukinori Akiyama, Rei Enatsu, Toru Hirano, Nobuhiro Mikuni Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Improvement of memory impairments in poststroke patients by hyperbaric oxygen therapy.
Objective: Several recent studies have shown that hyperbaric oxygen (HBO₂) therapy carry cognitive and motor therapeutic effects for patients with acquired brain injuries. The goal of this study was to address the specific effects of HBO₂ on memory impairments after stroke at late chronic stages. Method: A retrospective analysis was conducted on data of 91 stroke patients 18 years or older (mean age ∼60 years) who had either ischemic or hemorrhagic stroke 3–180 months before HBO₂ therapy (M = 30–35 months). The HBO₂ protocol included 40 to 60 daily sessions, 5 days per week, 90 min each, 100% oxygen at 2ATA, ...
Source: Neuropsychology - November 10, 2014 Category: Neurology Authors: Boussi-Gross, Rahav; Golan, Haim; Volkov, Olga; Bechor, Yair; Hoofien, Dan; Schnaider Beeri, Michal; Ben-Jacob, Eshel; Efrati, Shai Source Type: research

Recurrent Bleeding in Hemorrhagic Moyamoya Disease : Prognostic Implications of the Perfusion Status.
CONCLUSION: Decreased basal perfusion seems to be associated with recurrent bleeding. Revascularization might prevent recurrent stroke in hMMD by rectifying the perfusion abnormality. A larger-sized, controlled study is required to address this issue. PMID: 26962416 [PubMed]
Source: Journal of Korean Neurosurgical Society - March 12, 2016 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Left thalamus infarction in the thalamotuberal artery perfusion area causing subcortical diaschisis and transcortical sensory aphasia
The thalamus is related to language function, and some thalamic stroke cases can cause aphasia [1]. However, most previous cases reporting thalamic damage-induced ipsilateral subcortical diaschisis and aphasia were hemorrhagic stroke [1,2]. Only a few left thalamus infarction cases showed cortical hypoperfusion concerned with the aphasia, but no single-photon emission computed tomography (SPECT) or thalamic nucleus data were available [3]. Thus, aphasia pathology due to cortical hypoperfusion following thalamus infarction, especially with respect to thalamic nuclei, is still unknown.
Source: Journal of the Neurological Sciences - January 24, 2020 Category: Neurology Authors: Kosuke Matsuzono, Kohei Furuya, Azusa Karube, Akie Horikiri, Tadashi Ozawa, Takafumi Mashiko, Haruo Shimazaki, Reiji Koide, Ryota Tanaka, Shigeru Fujimoto Tags: Letter to the Editor Source Type: research

Diagnostic impact of baseline cerebral blood flow in patients with acute ischemic stroke prior to intravenous recombinant tissue plasminogen activator therapy
Conclusion: These results suggest that rt-PA therapy for patients with severe cerebral perfusion defects may cause SICH and baseline CBF may contribute to identify patients at high risk for SICH after intravenous rt-PA therapy.
Source: Clinical Neurology and Neurosurgery - February 22, 2013 Category: Neurosurgery Authors: Masaki Ito, Tetsuyuki Yoshimoto, Masahito Kawabori, Shin Fujimoto, Tohru Yamauchi, Hideshi Yamaguchi, Kouichi Tokuda, Sadao Kaneko Tags: Original articles Source Type: research

Reversible cerebral vasoconstriction syndrome associated with subarachnoid hemorrhage triggered by hydroxyzine pamoate
Reversible cerebral vasoconstriction syndrome (RCVS) is a disease of unknown etiology characterized by sudden headaches with or without additional neurologic deficits. RCVS has been documented in association with ischemic stroke and convexity subarachnoid hemorrhage (SAH) , but there are no reports of RCVS associated with SAH in conjunction with hydroxyzine pamoate treatment. Therefore, this is the first case of RCVS associated with SAH and hydroxyzine pamoate followed-up with N-isopropyl[123I]-p-iodoamphetamine single photon emission computed tomography-cerebral blood flow (IMP-SPECT-CBF) imaging and 3.0T magnetic resonan...
Source: Clinical Neurology and Neurosurgery - June 14, 2013 Category: Neurosurgery Authors: Fumihiro Matano, Yasuo Murai, Koji Adachi, Kenta Koketsu, Takayuki Kitamura, Akira Teramoto, Seiji Okubo, Yasuo Katayama, Tetsuro Sekine, Ryo Takagi, Shinichiro Kumita Tags: Case reports Source Type: research

123I-IMP-SPECT in a Patient with Cerebral Proliferative Angiopathy: A Case Report
We describe cerebral perfusion abnormalities in a patient with CPA by using N-isopropyl-p-[123I] iodoamphetamine single-photon emission computed tomography (123I-IMP-SPECT) and perfusion-weighted magnetic resonance imaging. The patient, a 13-year-old boy, had reversible focal neurological deficits unrelated to cerebral hemorrhage. 123I-IMP-SPECT at resting state showed preserved uptake within the vascular lesion, yet lower uptake in the area adjacent to the lesion. In addition, acetazolamide-stressed 123I-IMP-SPECT exhibited severely impaired cerebrovascular reactivity over the affected hemisphere, suggesting that his foca...
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2013 Category: Neurology Authors: Tomomi Kimiwada, Toshiaki Hayashi, Reizo Shirane, Teiji Tominaga Tags: Case Reports Source Type: research

White Matter Perivascular Spaces on Magnetic Resonance Imaging: Marker of Cerebrovascular Amyloid Burden? Brief Reports
Conclusions— This pilot study suggests a possible association between cerebrovascular amyloid deposition and CSO-PVS, with potential pathophysiological implications.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Charidimou, A., Hong, Y. T., Jager, H. R., Fox, Z., Aigbirhio, F. I., Fryer, T. D., Menon, D. K., Warburton, E. A., Werring, D. J., Baron, J.-C. Tags: PET and SPECT, Intracerebral Hemorrhage Brief Reports Source Type: research