Coronavirus Disease (COVID-19) Outbreak and Its Impact on Spinal Daily Practice : Preliminary Report from a Single (Regional) University Hospital in Republic of Korea.
Conclusion: The outbreak of COVID-19 affected our daily practice as OPD and ER visits reduced but did not affect the number of surgeries. We believe that this report will be informative to spinal specialists worldwide fighting the COVID-19 pandemic. PMID: 32455517 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - May 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Percutaneous Sacroplasty : Effectiveness and Long-Term Outcome Predictors.
Conclusion: PSP was effective for sacral insufficiency fractures and showed good long-term outcomes. Combined compression fractures in the thoracolumbar spine and degenerative lumbar pathologies could be possible poor outcome predictors. PMID: 32455518 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - May 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Influence of Antithrombotic Medication on the Risk of Chronic Subdural Hematoma Recurrence after Burr-Hole Surgery.
Conclusion: The present study found that preoperative antithrombotic medication was independently associated with CSDH recurrence. PMID: 32455519 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - May 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Comparison of Fusion Rate between Demineralized Bone Matrix versus Autograft in Lumbar Fusion : Meta-Analysis.
Authors: Han S, Park B, Lim JW, Youm JY, Choi SW, Kim DH, Ahn DK Abstract The demineralized bone matrix (DBM) as the bone graft material to increase the fusion rate was widely used in spinal fusion. The current study aimed to compare the fusion rate of DBM to the fusion rate of autograft in lumbar spine fusion via meta-analysis of published literature. After systematic search, comparative studies were selected according to eligibility criteria. Checklist (risk of bias assessment tool for non-randomized study) was used to evaluate the risk of bias of the included nonrandomized controlled studies. The corresponding 9...
Source: Journal of Korean Neurosurgical Society - May 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

The Influence of Comorbidities on Reoperations Following Primary Surgery of Lumbar Degenerative Diseases : A Nationwide Population-Based Retrospective Cohort Study from 2009-2016.
Authors: Park HK, Park SY, Lee PH, Park HR, Park SQ, Cho SJ, Chang JC Abstract Objective: Spinal degeneration is a progressive disease, worsening over time. Lumbar degenerative disease (LDD) is a major spinal disease in elderly patients. Surgical treatment is considered for medically intractable patients with LDD and reoperation after primary surgery is not uncommon. The surgical outcome is occasionally unpredictable because of comorbidities. In the present study, the relationship between comorbidities and the incidence of reoperation for LDD over time was determined. Methods: The claims data of the health insu...
Source: Journal of Korean Neurosurgical Society - May 22, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Radiosurgery for Cerebral Arteriovenous Malformation (AVM) : Current Treatment Strategy and Radiosurgical Technique for Large Cerebral AVM : Review Article.
Authors: Byun J, Kwon DH, Lee DH, Park W, Park JC, Ahn JS Abstract Arteriovenous malformations (AVMs) are congenital anomalies of the cerebrovascular system. AVM harbors 2.2% annual hemorrhage risk in unruptured cases and 4.5% annual hemorrhage risk of previously ruptured cases. Stereotactic radiosurgery (SRS) have been shown excellent treatment outcomes for patients with small- to moderated sized AVM which can be achieved in 80-90% complete obliteration rate with a 2-3 years latency period. The most important factors are associated with obliteration after SRS is the radiation dose to the AVM. In our institutional ...
Source: Journal of Korean Neurosurgical Society - May 21, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

INSPIRE Neuro-Spinal ScaffoldTM : An Implantable Alternative to Stem-Cell Therapy for Endogenous Repair in Spinal Cord Injury.
Authors: Brown N PMID: 32407612 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - May 15, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Surgical Management of Complex Spinal Cord Lipomas : A New Perspective.
Authors: Pang D Abstract This review summarises the classification, anatomy and embryogenesis of complex spinal cord lipomas, and describes in some detail the new technique of total lipoma resection and radical reconstruction of the affected neural placode. Its specific mission is to tackle two main issues surrounding the management of complex dysraphic lipomas : whether total resection confers better long term benefits than partial resection, and whether total resection does better than conservative treatment, i.e., no surgery, for asymptomatic lipomas. Accordingly, the 24 years progression-free survival data of t...
Source: Journal of Korean Neurosurgical Society - May 14, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Urological Evaluation of Tethered Cord Syndrome.
Authors: Park K Abstract To describe how to perform urological evaluation in children with tethered cord syndrome (TCS). Although a common manifestation of TCS is the development of neurogenic bladder in developing children, neurosurgeons often face difficulty in detecting urological problems in patients with TCS. From a urological perspective, diagnosis of TCS in developing children is further complicated due to the differentiation between neurogenic bladder dysfunctions and transient bladder dysfunctions owing to developmental problems. Due to the paucity of evidence regarding evaluation prior to and after unteth...
Source: Journal of Korean Neurosurgical Society - May 14, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Perspectives on Spinal Dysraphism : Past, Present, and Future.
This article recounts the author's personal views and recollections of the history, conception of embryogenetic theories, application of intraoperative electrophysiology, and development of prospective treatment recommendations of several important spinal dysraphic malformations, including limited dorsal myeloschisis, dermal sinus tract, retained medullary cord, terminal myelocystocoele, and complex spinal cord lipomas. PMID: 32392668 [PubMed] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - May 14, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

The Value of Tumor Treating Fields in Glioblastoma.
Authors: Zhang C, Du J, Xu W, Huang H, Gao L Abstract Glioblastoma (GBM) is one of the most common tumors of the central nervous system, which is the most lethal brain cancer. GBM treatment is based primarily on surgical resection, combined with radiotherapy and chemotherapy. Despite the positive treatment, progression free survival and overall survival were not significantly prolonged because GBM almost always recurs. We are always looking forward to some new and effective treatments. In recent years, a novel treatment method called tumor treating fields (TTFields) for cancer treatment has been proposed. TTFields ...
Source: Journal of Korean Neurosurgical Society - May 10, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Is It Possible to Replace Microendoscopic Discectomy with Percutaneous Transforaminal Discectomy for Treatment of Lumbar Disc Herniation? A Meta-Analysis Based on Recurrence and Revision Rate.
Conclusion: PTED has a number of advantages because it is a minimally invasive surgery, but its recurrence and revision rates are higher than MED. Therefore, MED should not be completely replaced by PTED. PMID: 32380585 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - May 10, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

A Preliminary Study of the Association between SOX17 Gene Variants and Intracranial Aneurysms Using Exome Sequencing.
Conclusion: No significant association between SOX17 gene variants and IA were noted in the Korean population. A large-scale exome sequencing study is necessary to investigate any Korean-specific genetic susceptibility to IA. PMID: 32380586 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - May 10, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Single-Stage Reconstruction with Titanium Mesh for Compound Comminuted Depressed Skull Fracture.
Conclusion: Immediate bony fragments replacement and reconstruction with reconstruction titanium mesh for FCCD did not increase infectious sequelae, even though FCCD involved sinus. This suggests that immediate single-stage reconstruction with titanium mesh for FCCD is a suitable surgical option with potential benefits in terms of cost-effectiveness, safety, and cosmetic and psychological outcomes. PMID: 32380587 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - May 10, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Secondary Neurulation Defects-1 : Retained Medullary Cord.
This article reviews the literature to elucidate the pathoembryogenesis, clinical significance and treatment of RMCs. PMID: 32336057 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - April 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Spinal Dysraphism in the Last Two Decades : What I Have Seen during the Era of Dynamic Advancement.
Authors: Wang KC Abstract Compared to any other decade, the last two decades have been the most dynamic period in terms of advances in the knowledge on spinal dysraphism. Among the several factors of rapid advancement, such as embryology during secondary neurulation and intraoperative neurophysiological monitoring, there is no doubt that Professor Dachling Pang stood high amidst the period. I review here the last two decades from my personal point of view on what has been achieved in the field of spinal dysraphism, focusing on occult tethered cord syndrome, lumbosacral lipomatous malformation, terminal myelocystoce...
Source: Journal of Korean Neurosurgical Society - April 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Terminal Myelocystocele : Pathoembryogenesis and Clinical Features.
Authors: Lee JY, Kim KH, Wang KC Abstract There has been confusion in the classification of terminal myelocystocele (TMCC) due to its diverse morphology and vague pathoembryogenesis. TMCC could be summarized as having the essential features of an elongated caudal spinal cord extruding out of the dorsal extraspinal space that fuses with the subcutaneous fat, which is in the shape of a trumpet-shaped cerebrospinal fluid-filled cyst. The extraspinal portion of the extruded spinal cord is nonfunctional. The morphological features suggest that TMCC is formed during secondary neurulation, specifically the failure of the ...
Source: Journal of Korean Neurosurgical Society - April 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Syringomyelia in the Tethered Spinal Cords.
Authors: Lee JY, Kim KH, Wang KC Abstract Cases of syringomyelia associated with spinal dysraphism are distinct from those associated with hindbrain herniation or arachnoiditis in terms of the suspected pathogenetic mechanism. The symptoms of terminal syringomyelia are difficult to differentiate from the symptoms caused by spinal dysraphism. Nonetheless, syringomyelia has important clinical implications, as it is an important sign of cord tethering. The postoperative assessment of syringomyelia should be performed with caution. PMID: 32336060 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - April 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Enlargement of Extraspinal Cysts in Spinal Dysraphism : A Reason for Early Untethering.
Authors: Kim KH, Wang KC, Lee JY Abstract Some types of spinal dysraphism can be accompanied by extraspinal cysts, including myelomeningocele, myelocystocele, myelocele, meningocele, limited dorsal myeloschisis, lipomyelomeningocele, and terminal myelocystocele. Each disease is classified according to the developmental mechanism, embryologic process, site of occurrence, or internal structure of the extraspinal cyst. In most cystic spinal dysraphisms except meningocele, part of the spinal cord is attached to the cyst dome. Most open spinal dysraphisms pose a risk of infection and require urgent surgical intervention...
Source: Journal of Korean Neurosurgical Society - April 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Preface : Invited Issue Editor Professor Dachling Pang and the Changing Concepts in Spinal Dysraphism during the Last Two Decades.
Authors: Kim CY, Kim SK PMID: 32336062 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - April 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Retethering : A Neurosurgical Viewpoint.
This article reviews the literature on the incidence and timing of deterioration, predisposing factors for retethering, clinical manifestations, diagnosis, surgical treatment and its complications, clinical outcomes, prognostic factors after retethering surgery and preventive measures of retethering. Current practice and opinions of Seoul National University Children's Hospital team were added in some parts. The literature shows a wide range of data regarding the incidence, rate and degree of surgical complications and long-term outcomes. The method of prevention is still one of the main topics of this entity. Although alt...
Source: Journal of Korean Neurosurgical Society - April 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Junctional Neural Tube Defect.
Authors: Eibach S, Pang D Abstract Junctional neurulation represents the most recent adjunct to the well-known sequential embryological processes of primary and secondary neurulation. While its exact molecular processes, occurring at the end of primary and the beginning of secondary neurulation, are still being actively investigated, its pathological counterpart -junctional neural tube defect (JNTD)- had been described in 2017 based on three patients whose well-formed secondary neural tube, the conus, is widely separated from its corresponding primary neural tube and functionally disconnected from corticospinal con...
Source: Journal of Korean Neurosurgical Society - April 28, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Covered Stenting Is an Effective Option for Traumatic Carotid Pseudoaneurysm with Promising Long-Term Outcome.
Conclusion: Satisfactory procedural and long-term outcomes were obtained, suggesting that covered stenting is an effective option for traumatic carotid pseudoaneurysm. PMID: 32272508 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - April 11, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Dexamethasone Interferes with Autophagy and Affects Cell Survival in Irradiated Malignant Glioma Cells.
Conclusion: Dexamethasone increased cell survival in p53 mutated malignant glioma cells and increased autophagy in PTEN-mutant malignant glioma cell but not in PTEN-wildtype cell. The difference of autophagy response could be mediated though the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin signaling pathway. PMID: 32272509 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - April 11, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Correlation between the Position of the Pituitary Stalk as Determined by Diffusion Tensor Imaging and Its Location as Determined at the Time of Surgical Resection of Pituitary Adenomas.
Conclusion: This study shows that DTI can identify the position of the HHT and thus the position of the PS with a high degree of reliability. PMID: 32182411 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - March 19, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

The Correlation between E-Selectin S128R Gene Polymorphism and Ischemic Stroke in Chinese Population : A Meta-Analysis.
Authors: Yang X, Ma R, Zhang Y, Wang G Abstract To perform a systematic review of the data collected from case-control studies conducted earlier to investigate the correlation between E-selectin S128R polymorphism and ischemic stroke (IS) risk among the Chinese population. The PubMed, Web of Science, Chinese biomedical literature database (CBM), Chinese databases China National Knowledge Infrastructure (CNKI), WanfangData knowledge service platform (Wanfang Data), and information resource integration service platform (VIP) Databases were searched to retrieve case-control studies on the correlation between E-selecti...
Source: Journal of Korean Neurosurgical Society - March 19, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Rutin Improves Bone Histomorphometric Values by Reduction of Osteoclastic Activity in Osteoporosis Mouse Model Induced by Bilateral Ovariectomy.
Conclusion: The present study demonstrated that rutin has therapeutic effects on improving bone histomorphometric values in an OVX mouse model. The improvement in histomorphometric values may be associated with the reduction of osteoclastic activity via inhibition of IL-1β, IL-6, and TNF-α. In future studies, the mechanism for the effect of rutin on osteoporosis should be demonstrated more clearly to use rutin in human osteoporosis. PMID: 32172552 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - March 18, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Expression and Significance of MicroRNA155 in Serum of Patients with Cerebral Small Vessel Disease.
This study aimed to investigate the changes and significance of microRNA155 levels in serum of patients with cerebral small vessel disease (CSVD). Methods: Thirty patients with CSVD who met the inclusion criteria were selected and divided into eight patients with lacunar infarction (LI) group and 22 patients with multiple lacunar infarction (MLI) combined with white matter lesions (WML) group according to the results of head magnetic resonance imaging (MRI). Thirty samples from healthy volunteers without abnormalities after head MRI examination were selected as the control group. The levels of serum microRNA155 in each...
Source: Journal of Korean Neurosurgical Society - March 12, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Thyroid-Stimulating Hormone-Secreting Pituitary Adenomas : Single Institutional Experience of 14 Consecutive Cases.
Authors: Byun J, Kim JH, Kim YH, Cho YH, Hong SH, Kim CJ Abstract Objective: Thyroid-stimulating hormone (TSH)-secreting pituitary adenoma (PA) is an extremely rare functioning form of PA that accounts for 0.7-2% of all such cases. The previously reported outcomes of the surgical removal of TSH-PA are poor. Owing to its extremely low incidence, most available reports on TSH-PA are case reports or small case series. Thus, we investigated the clinical and endocrinological outcomes of surgically treated TSH-PA through our institutional series. Methods: We retrospectively reviewed 14 consecutive cases of surgically...
Source: Journal of Korean Neurosurgical Society - March 11, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

An Optimization of AAV-82Q-Delivered Rat Model of Huntington's Disease.
Conclusion: Based on the results from the present study, high dose of AAV2-82Q is the optimum titer for establishing a Huntington rat model. Delivery of high dose of human AAV2-82Q resulted in the manifestation of Huntington behaviors and optimum expression of the huntingtin protein in vivo. PMID: 32131152 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - March 8, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Endovascular Treatment of Traumatic Arteriovenous Fistula in Young Adults with Pulsatile Tinnitus.
Authors: Kim HS, Song JH, Oh JK, Ahn JH, Kim JH, Chang IB Abstract Traumatic arteriovenous fistulas (AVFs) involving the external carotid artery are exceedingly rare in young adults. Since an AVF is the most common life-threatening cause for pulsatile tinnitus (PT), meticulous evaluation and treatment of patients with PT is crucial. Here, we present two traumatic AVF cases treated with coil embolization leading to no residual fistulous connections followed by an immediate and complete resolution of PT. A 20-year-old man developed left ear tinnitus three months after a traumatic brain injury involving the right temp...
Source: Journal of Korean Neurosurgical Society - March 6, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Can Computed Tomographic Angiography Be Used to Predict Who Will Not Benefit from Endovascular Treatment in Patients with Acute Ischemic Stroke? The CTA-ABC Score.
The objective of this study was to develop a score to predict patients with acute ischemic stroke (AIS) who will not benefit from endovascular treatment (EVT) using computed tomographic angiography (CTA) parameters. Methods: The CTA-ABC score was developed from 3 scales previously described in the literature: the Alberta Stroke Program Early CT Score (0-5 points, 3; 6-10 points, 0), the clot burden score (0-3 points, 1; 4-10 points, 0), and the leptomeningeal Collateral score (0-1 points, 2; 2-3 points, 0). We evaluated the predictive value of CTA parameters associated with symptomatic intracranial hemorrhage (sICH) or...
Source: Journal of Korean Neurosurgical Society - March 6, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Postoperative Non-Pathological Fever Following Posterior Cervical Fusion Surgery : Is Laminoplasty a Better Preventive Method than Laminectomy?
Conclusion: Patients who develop delayed fever 4 days after posterior cervical fusion surgery using CPS are more likely to have non-pathologic fever than surgical site infection. Laminectomy is a significant risk factor for non-pathologic fever. PMID: 32126749 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - March 6, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Eversion Carotid Endarterectomy : A Short Review.
Authors: Davidovic LB, Tomic IZ Abstract Carotid endarterectomy (CEA) is the main procedure in carotid surgery, as well as the most frequent vascular procedure. Two techniques of CEA are available : eversion and conventional plus patch angioplasty. Eversion CEA is anatomic procedure that reduces ischemic and total operative time. Simultaneous correction of the joined carotid kinking and coiling is possible, easy and safe, while the usage of patch is excluded. Thanks to oblique shape of anastomosis, eversion CEA is associated with low risk of long-term restenosis. The false anastomotic aneurysms occurrence is very r...
Source: Journal of Korean Neurosurgical Society - March 4, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

The Evolution of Flow-Diverting Stents for Cerebral Aneurysms; Historical Review, Modern Application, Complications, and Future Direction.
Authors: Shin DS, Carroll CP, Elghareeb M, Hoh BL, Kim BT Abstract In spite of the developing endovascular era, large (15-25 mm) and giant (>25 mm) wide-neck cerebral aneurysms remained technically challenging. Intracranial flow-diverting stents (FDS) were developed to address these challenges by targeting aneurysm hemodynamics to promote aneurysm occlusion. In 2011, the first FDS approved for use in the United States market. Shortly thereafter, the Pipeline of Uncoilable or Failed Aneurysms (PUFS) study was published demonstrating high efficacy and a similar complication profile to other intracranial stents. Th...
Source: Journal of Korean Neurosurgical Society - March 4, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Milk Fat Globule-Epidermal Growth Factor VIII Ameliorates Brain Injury in the Subacute Phase of Cerebral Ischemia in an Animal Model.
CONCLUSION: Our findings suggest that MFG-E8 improves neurological function by suppressing inflammation and enhancing angiogenesis and neuronal proliferation in the subacute phase of cerebral infarction. PMID: 32120456 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - March 4, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Comparative Analysis of Surgical Outcomes of C1-2 Fusion Spine Surgery between Intraoperative Computed Tomography Image Based Navigation-Guided Operation and Fluoroscopy-Guided Operation.
CONCLUSION: Spinal navigation using intraoperative cone-beam CT scans is reliable for posterior fixation in unstable C1-2 pathologies and can be reduced the operative time. PMID: 32120457 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - March 4, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Can Breast Asymmetry Following the Treatment of Juvenile Idiopathic Scoliosis with Growing Rod Be Prevented? : A Preliminary Analysis.
Conclusion: In the late follow-up period, BA was detected in 50% of the patients with JIS who achieved final fusion after treatment with growing rod. In majority of the patients, left breast was larger. The patients with JIS and their families can be informed prior to the operation about the probability of BA seen in the follow-up period after fusion. PMID: 32024355 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - February 8, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Accuracy Analysis of Iliac Screw Using Freehand Technique in Spinal Surgery : Relation between Screw Breach and Revision Surgery.
Authors: Lee S, Jung SK, Keshen SG, Lewis SJ, Park JH Abstract Objective: To analyze the accuracy of iliac screws using freehand technique performed by the same surgeon. We also analyzed how the breach of iliac screws was related to the clinical symptoms resulting in revision surgery. Methods: From January 2009 to November 2015, 100 patients (193 iliac screws) were analyzed using postoperative computed tomography scans. The breaches were classified based on the superior, inferior, lateral, and medial iliac wall violation by the screw. According to the length of screw extrusion, the classification grades were as...
Source: Journal of Korean Neurosurgical Society - January 15, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Spine Computed Tomography to Magnetic Resonance Image Synthesis Using Generative Adversarial Networks : A Preliminary Study.
Conclusion: This was the first study to apply GANs to synthesize spine MR images from CT images. Despite the small dataset of 280 pairs, the synthetic MR images were relatively well implemented. Synthesis of medical images using GANs is a new paradigm of artificial intelligence application in medical imaging. We expect that synthesis of MR images from spine CT images using GANs will improve the diagnostic usefulness of CT. To better inform the clinical applications of this technique, further studies are needed involving a large dataset, a variety of pathologies, and other MR sequence of the lumbar spine. PMID: 31931556...
Source: Journal of Korean Neurosurgical Society - January 15, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Paradigm Shift in Intra-Arterial Mechanical Thrombectomy for Acute Ischemic Stroke : A Review of Randomized Controlled Trials after 2015.
Authors: Sheen JJ, Kim YW Abstract Three randomized control trials (RCTs), published in 2013, investigated efficacy of mechanical thrombectomy in large vessel occlusions and did not show better results compared to intravenous (IV) recombinant tissue-type plasminogen activator (tPA) alone. However, most clinicians treating stroke consider mechanical thrombectomy as the standard treatment rather than using IV tPA alone. This paradigm shift was based on five RCTs investigating efficacy of mechanical thrombectomy in acute ischemic stroke conducted from 2010 to 2015. They demonstrated that mechanical thrombectomy was ef...
Source: Journal of Korean Neurosurgical Society - January 11, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

The Influential Articles and Title Words in the Journal of Korean Neurological Society Publications between the Years 2016 to 2018.
Authors: Im SB, Chung M, Kim BT PMID: 31916425 [PubMed] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - January 11, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Evaluation of Cumulative and Conditional Antibiotic Release from Vancomycin-Embedded Fibrin Sealant and Its Antibacterial Activity : An In Vitro Study.
CONCLUSION: This study suggests that fibrin sealant can provide an efficient vehicle for antibiotic drug release in a wide range of neurosurgical procedures and the safe and effective therapeutic dose will be at the concentration embedded of 4.167 mg/disc or more of vancomycin. PMID: 31916426 [PubMed] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - January 11, 2020 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Neuroprotective Effects of Lacosamide in Experimental Peripheral Nerve Injury in Rats : A Prospective Randomized and Placebo-Controlled Trial.
Conclusion: The biochemical and histological analyses revealed that lacosamide has neuroprotective effect in PNI in rats. This neuroprotective capacity depends on its scavenger role for free oxygen radicals by increasing antioxidant enzyme activity. PMID: 31805756 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - December 8, 2019 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Clinical Safety and Effectiveness of Stent-Assisted Coil Embolization with Neuroform Atlas Stent in Intracranial Aneurysm.
Conclusion: In this study, we found that stent-assisted coil embolization with NeuroForm Atlas stent may be safe and effective in the treatment of wide-neck intracranial aneurysms. NeuroForm Atlas SAC is feasible for the treatment of both ruptured and unruptured wide-neck aneurysms. PMID: 31805757 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - December 8, 2019 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Current Status and Future Strategies to Treat Spinal Cord Injury with Adult Stem Cells.
Authors: Jeong SK, Choi I, Jeon SR Abstract Spinal cord injury (SCI) is one of the most devastating conditions and many SCI patients suffer neurological sequelae. Stem cell therapies are expected to be beneficial for many patients with central nervous system injuries, including SCI. Adult stem cells (ASCs) are not associated with the risks which embryonic stem cells have such as malignant transformation, or ethical problems, and can be obtained relatively easily. Consequently, many researchers are currently studying the effects of ASCs in clinical trials. The environment of transplanted cells applied in the injured...
Source: Journal of Korean Neurosurgical Society - December 8, 2019 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Anterior Approach Following Intraoperative Reduction for Cervical Facet Fracture and Dislocation.
Conclusion: Anterior approach following intraoperative reduction monitored by somatosensory-evoked potentials under general anesthesia for cervical dislocation and locked facets is a relatively safe and effective alternative when cervical alignment is achieved by intraoperative reduction. PMID: 31805759 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - December 8, 2019 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Gamma Knife Radiosurgery Using Co-Registration with PET-CT and MRI for Recurrent Nasopharyngeal Carcinoma with Previous Radiotherapy : A Single Center 14-Year Experience.
Conclusion: GKS is an acceptable salvage treatment option for patients with recurrent NPC who previously received radiation therapy. PET-CT and MRI co-registration for dose planning can help achieve local control of recurrent NPC. PMID: 31775216 [PubMed - as supplied by publisher] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - November 30, 2019 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

In-Vitro Study of Urokinase Thrombolysis Following Stereotactic Aspiration of Intracerebral Hematoma.
Authors: Son W, Park J, Kang DH, Han YM, Choi YJ, Ohk B Abstract Objective: A consensus regarding the ideal regimen for urokinase (UK) thrombolysis subsequent to stereotactic spontaneous intracerebral hemorrhage aspiration has yet to be established. The purpose of this study is to evaluate the efficacy of UK thrombolysis relative to when the regimen is changed. Methods: Venous blood from 30 heathy volunteers was obtained for this in-vitro study. Various concentrations of UK solution were added to microcentrifuge tubes containing the clotted blood. The efficacy of UK thrombolysis was identified by checking the w...
Source: Journal of Korean Neurosurgical Society - November 23, 2019 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Comparison of Biomechanical Properties of Dura Mater Substitutes and Cranial Human Dura Mater : An In Vitro Study.
CONCLUSION: An important dura mater graft property is biomechanical similarity to cranial human dura mater. This biomechanical study contributed to the future development of artificial dura mater substitutes with biomechanical properties similar to those of human dura mater. PMID: 31679317 [PubMed] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - November 5, 2019 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research