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Nutrition: Manganese

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Total 38 results found since Jan 2013.

Chrysophanol attenuates nitrosative/oxidative stress injury in a mouse model of focal cerebral ischemia/reperfusion
Publication date: Available online 25 August 2018Source: Journal of Pharmacological SciencesAuthor(s): Yongmei Zhao, Yuyou Huang, Yalan Fang, Haiping Zhao, Wenjuan Shi, Jincheng Li, Yunxia Duan, Yuwei Sun, Li Gao, Yumin LuoAbstractNitrosative/oxidative stress plays an important role in neuronal death following cerebral ischemia/reperfusion (I/R). Chrysophanol (CHR) has been shown to afford significant neuroprotection on ischemic stroke, however, whether its mechanism is related to attenuating nitrosative/oxidative stress is not clear. In the present study, we investigated the effect of CHR on neuronal injury related to nit...
Source: Journal of Pharmacological Sciences - August 25, 2018 Category: Drugs & Pharmacology Source Type: research

Iron Metabolism and Brain Development in Premature Infants
Yafeng Wang1,2,3, Yanan Wu2, Tao Li1,2,3, Xiaoyang Wang2,4 and Changlian Zhu2,3* 1Department of Neonatology (NICU), Children’s Hospital Affiliated Zhengzhou University, Zhengzhou, China 2Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China 3Department of Clinical Neuroscience, Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden 4Department of Physiology, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Got...
Source: Frontiers in Physiology - April 24, 2019 Category: Physiology Source Type: research

Association between Dietary Manganese Intake and Mortality from Cardiovascular Disease in Japanese Population: The Japan Collaborative Cohort Study
CONCLUSIONS: Our study is the first to show the prospective association between dietary Mn intake and reduced risk of mortality from CVD in the Japanese population.PMID:35082202 | DOI:10.5551/jat.63195
Source: Journal of Atherosclerosis and Thrombosis - January 27, 2022 Category: Cardiology Authors: Ouyang Meishuo Ehab S Eshak Isao Muraki Renzhe Cui Kokoro Shirai Hiroyasu Iso Akiko Tamakoshi Source Type: research

Preconditioning exercise reduces hippocampal neuronal damage via increasing Klotho expression in ischemic rats
In this study, we assessed neuroprotective effects of preconditioning exercise in rats (treadmill running at a speed of 20m/min,30min/day, six days/week, for3 weeks) on hippocampal Klotho and MnSOD expression in the brain using an animal model of stroke, middle cerebral artery occlusion (MCAO). Our study revealed a reduction in hippocampal Klotho and MnSOD expression as well as CA1 neuronal activity in MCAO compared to the sham group. Exercise prevented the ischemia-induced decline in Klotho and MnSOD expression levels as well as CA1 neuronal activity in Exercise + MCAO compared to the MCAO group. Also, exercise significan...
Source: Brain Research Bulletin - August 2, 2022 Category: Neurology Authors: Maryam Soleimani Karizmeh Maryam Shabani Mostafa Shabani Maryam Sardari Javad Fahanik Babaei Fatemeh Nabavizadeh Seyed Shahabeddin Sadr Soheila Adeli Source Type: research

Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits
Conclusions: Lag 0–2 OPDTT was associated with ED visits for multiple cardiorespiratory outcomes, providing support for the utility of OPDTT as a measure of fine particle toxicity. https://doi.org/10.1289/EHP1545 Received: 23 December 2016 Revised: 4 August 2017 Accepted: 12 August 2017 Published: 26 October 2017 Please address correspondence to J.Y. Abrams, Centers for Disease Control and Prevention, NCEZID/DHCPP, 1600 Clifton Rd. NE, CDC Mailstop A30, Atlanta, GA 30333 USA. Telephone: (404) 639-5121. Email: jabrams@cdc.gov Supplemental Material is available online (https://doi.org/10.1289/EHP1545). The authors ...
Source: EHP Research - October 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Urine Arsenic and Arsenic Metabolites in U.S. Adults and Biomarkers of Inflammation, Oxidative Stress, and Endothelial Dysfunction: A Cross-Sectional Study
Conclusion: In a cross-sectional study of U.S. adults, we observed some positive associations of uAs and toenail As concentrations with biomarkers potentially relevant to CVD pathogenesis and inflammation, and evidence of a higher capacity to metabolize inorganic As was negatively associated with a marker of oxidative stress. https://doi.org/10.1289/EHP2062 Received: 14 April 2017 Revised: 13 November 2017 Accepted: 15 November 2017 Published: 15 December 2017 Address correspondence to S.F. Farzan, 2001 N. Soto St., Los Angeles, CA, 90032. Telephone: (323)-442-5101; Email: sffarzan@usc.edu Supplemental Material is ava...
Source: EHP Research - December 16, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Acquired hepatocerebral degeneration (AHD): a peculiar neurological impairment in advanced chronic liver disease
AbstractWe discuss the case of a rare and often unrecognized neurologic syndrome, called Acquired Hepatocerebral Degeneration (AHD), observed in patients with advanced liver disease and portosystemic shunts. The clinical manifestations can be very heterogeneous and in our case included a combination of cerebellar and extrapyramidal signs, arisen in a period of few days. Brain Magnetic Resonance Imaging (MRI) showed, in T1-weighted images, diffuse bilateral hyper intensities in basal ganglia and biemispheric brain and cerebellar cortices, resembling paramagnetic deposits. No other neurological impairments, like stroke, infe...
Source: Metabolic Brain Disease - January 15, 2018 Category: Neurology Source Type: research

Evaluation of intestinal injury, inflammatory response and oxidative stress following intracerebral hemorrhage in mice.
Abstract Intestinal injury is a common complication following intracerebral hemorrhage (ICH), which leads to malnutrition, impaired immunity and unsatisfactory prognosis. Previous studies have revealed the pathogenesis of intestinal injury following traumatic brain injury using ischemic stroke models. However, the effects of ICH on intestinal injury remain unknown. The present study aimed to investigate the pathological alterations and molecular mechanism, as well as the time course of intestinal injury following ICH in mice. Male C57BL/6 mice were randomly divided into the following seven groups (n=6 mice/group...
Source: International Journal of Molecular Medicine - July 4, 2018 Category: Molecular Biology Authors: Cheng Y, Zan J, Song Y, Yang G, Shang H, Zhao W Tags: Int J Mol Med Source Type: research

MRI Tracking of iPS Cells-Induced Neural Stem Cells in Traumatic Brain Injury Rats.
In conclusion, using an in vivo MRI tracking technique to trace the fate of iPS cells-induced NSCs in host brain is feasible. PMID: 30574806 [PubMed - as supplied by publisher]
Source: Cell Transplantation - December 21, 2018 Category: Cytology Authors: Jiang L, Li R, Tang H, Zhong J, Sun H, Tang W, Wang H, Zhu J Tags: Cell Transplant Source Type: research