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Infectious Disease: Pandemics

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Total 2877 results found since Jan 2013.

Treatments in Ischemic Stroke: Current and Future
Background and Aim: Despite progress made over the last 30 years, stroke is still a leading cause of disability and mortality; likewise, its burden is expected to increase over the next decades, due to population growth and aging. The development of drugs with better safety-efficacy profiles as well as strategies able to improve ischemic stroke management from the pre-hospital setting is needed.Summary: The pathophysiology of ischemic stroke involves multiple pathways resulting in cerebral artery obstruction and brain tissue ischemia. To date, the only approved drug for acute ischemic stroke is intravenous thrombolytic alt...
Source: European Neurology - August 2, 2022 Category: Neurology Source Type: research

The effects of racism and resilience on Black stroke- survivor quality of life: Study protocol and rationale for a mixed-methods approach
This study aims to examine the effects of experiences of racism and resilience on Black SS QoL during early stroke recovery. This article presents the study protocol.Methods and analysesThis will be a prospective observational mixed-methods study. Black community-dwelling adults who are within 4 weeks of a stroke will be eligible for inclusion. Baseline measures will include the exposure variables of experiences of racism and resilience. Covariates measured at baseline include sociodemographic variables (age, sex, marital status, education, income, health insurance, employment status, number of people in household, residen...
Source: Frontiers in Neurology - August 10, 2022 Category: Neurology Source Type: research

Effects of healthcare system transformations spurred by the COVID-19 pandemic on management of stroke and STEMI: a registry-based cohort study in France
Conclusions The pandemic did not markedly alter the functioning of the emergency network. Although stroke patient management deteriorated, the resilience of the STEMI pathway was linked to its stronger structuring. Transversal reorganisations, aiming at concentrating resources on emergency care, contributed to maintenance of the quality of care. Trial registration number NCT04979208.
Source: BMJ Open - September 21, 2022 Category: General Medicine Authors: Lesaine, E., Francis-Oliviero, F., Domecq, S., Bijon, M., Cetran, L., Coste, P., Lhuaire, Q., Miganeh-Hadi, S., Pradeau, C., Rouanet, F., Sevin, F., Sibon, I., Saillour-Glenisson, F., AVICOVID group, Faucheux, Leca Radu, Seignolles, Chazalon, Dan, Lucas, Tags: Open access, Public health, COVID-19 Source Type: research

National stroke management plan in Uruguay: Challenges and opportunities
Stroke accounts for 5.5% of the national Global Burden of Disease (GBD) and ~2,000 deaths per year in Uruguay. To respond to this medical emergency, the Ministry of Public Health (MPH) of Uruguay devised the National Stroke Plan (NSP). Scientific associations, universities, scholars, and patient organizations, both at the national and international levels, took part in the process, which ended with the generation of the national stroke management guidelines, including measures based on the best evidence available. This was accompanied by presidential regulatory decrees and several ordinances that set the foundations of the...
Source: Frontiers in Neurology - February 1, 2023 Category: Neurology Source Type: research

Association of the COVID-19 pandemic on stroke admissions and treatment globally: a systematic review
Conclusions During the COVID-19 pandemic, many populations hesitated to seek medical attention, decreasing hospital admissions for less severe strokes and increasing hospitalisation of more severe cases and mortality. The effect of the pandemic on society and healthcare systems needs to be addressed to improve stroke treatment pathways and prepare for potential future epidemics. PROSPERO registration number CRD42021248564.
Source: BMJ Open - March 17, 2023 Category: General Medicine Authors: Van Dusen, R. A., Abernethy, K., Chaudhary, N., Paudyal, V., Kurmi, O. Tags: Open access, Cardiovascular medicine, COVID-19 Source Type: research

Stroke patterns and outcomes during the second wave of COVID-19 pandemic: a cross-sectional study
CONCLUSION: The factors that cause the delayed transfer to the hospital and onset of treatment should be addressed. Patient counseling about the likely prognosis can be done after evaluating the probable outcome based on the NIHSS score and median duration of hospital stay. Nevertheless, mechanisms should be developed to reduce the prehospital delay at the ground level as well as at the policy level.PMID:37363610 | PMC:PMC10289718 | DOI:10.1097/MS9.0000000000000722
Source: Annals of Medicine - June 26, 2023 Category: Internal Medicine Authors: Bikram P Gajurel Subarna Giri Parishma Tamrakar Anupama Pandeya Niraj Gautam Aashish Shrestha Ragesh Karn Reema Rajbhandari Rajeev Ojha Source Type: research

COVID-19 presenting as stroke.
CONCLUSIONS: Timely assessment and hyperacute treatment is the key to minimize mortality and morbidity of patients with acute stroke. Stroke teams should be wary of the fact that COVID-19 patients can present with cerebrovascular accidents and dawn appropriate personal protective equipment in every suspected patient. Further studies are urgently needed for a comprehensive understanding of the neurological pathology of COVID-19 and its effects on the nervous system. PMID: 32360439 [PubMed - as supplied by publisher]
Source: Brain, Behavior, and Immunity - April 27, 2020 Category: Neurology Authors: Avula A, Nalleballe K, Narula N, Sapozhnikov S, Dandu V, Toom S, Glaser A, Elsayegh D Tags: Brain Behav Immun Source Type: research

Interventional Stroke Care in the Era of COVID-19
The current coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 has led to immense strain on healthcare systems and workers. Patients with severe symptoms of COVID-19 may also present with acute neurological emergencies such as ischemic stroke. Ischemic stroke in these patients may result from COVID-19 related complications or decompensation of previously asymptomatic cerebrovascular disorders, or concurrent ischemic stroke from common stroke risk factors in a patient with COVID-19. Acute ischemic stroke patients with large vessel occlusions require emergent triage, intensive c...
Source: Frontiers in Neurology - May 7, 2020 Category: Neurology Source Type: research

COVID-19: Stroke Admissions, Emergency Department Visits, and Prevention Clinic Referrals.
Abstract We assessed the impact of the coronavirus disease 19 (COVID-19) pandemic on code stroke activations in the ED, stroke unit admissions, and referrals to the stroke prevention clinic at London's regional stroke center, serving a population of 1.8 million in Ontario, Canada. We found a 20% drop in the number of code strokes in 2020 compared to 2019, immediately after the first cases of COVID-19 were officially confirmed. There were no changes in the number of stroke admissions and there was a 22% decrease in the number of clinic referrals, only after the provincial lockdown. Our findings suggest that the dec...
Source: The Canadian Journal of Neurological Sciences - May 25, 2020 Category: Neurology Authors: Bres Bullrich M, Fridman S, Mandzia JL, Mai LM, Khaw A, Vargas Gonzalez JC, Bagur R, Sposato LA Tags: Can J Neurol Sci Source Type: research

COVID-19 and \ stroke: Incidental, triggered or causative
Rohit Bhatia, M V. Padma SrivastavaAnnals of Indian Academy of Neurology 2020 23(3):318-324 Stroke is a serious neurological complication observed during the ongoing COVID-19 (coronavirus associated disease 2019) pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome, corona virus 2) and includes both ischemic stroke and intracerebral haemorrhage. We reviewed factors that could potentially contribute to the occurrence of stroke among patients with COVID-19. There could be an interaction between the conventional risk factors of stroke, infection, systemic inflammatory response and plaque destabilisation. Inflamma...
Source: Annals of Indian Academy of Neurology - June 9, 2020 Category: Neurology Authors: Rohit Bhatia M V. Padma Srivastava Source Type: research

Impact of the COVID-19 pandemic on hyperacute stroke treatment: experience from a comprehensive stroke centre in Singapore
AbstractThe Coronavirus disease 2019 (COVID-19) pandemic is rapidly evolving and affecting healthcare systems across the world. Singapore has escalated its alert level to Disease Outbreak Response System Condition (DORSCON) Orange, signifying severe disease with community spread. We aimed to study the overall volume of AIS cases and the delivery of hyperacute stroke services during DORSCON Orange. This was a single-centre, observational cohort study performed at a comprehensive stroke centre responsible for AIS cases in the western region of Singapore, as well as providing care for COVID-19 patients. All AIS patients revie...
Source: Journal of Thrombosis and Thrombolysis - July 12, 2020 Category: Hematology Source Type: research

Where have our patients gone? The impact of COVID ‐19 on stroke imaging and intervention at an Australian stroke centre
ConclusionsThe significant decrease in volume of ‘code stroke’ activations and acute stroke imaging following lockdown was accompanied by a concomitant decrease in patients with LVOs and ECRs. The decrease in imaging was therefore not driven purely by patients with mild strokes and stroke mimics, but also included those with severe strokes. Si nce Australia had a low prevalence of COVID‐19, this observed decrease cannot be attributed to hospital congestion and is instead likely driven by patient fear.
Source: Journal of Medical Imaging and Radiation Oncology - August 19, 2020 Category: Radiology Authors: Shalini A Amukotuwa, Roland Bammer, Julian Maingard Tags: Medical Imaging —Original Article Source Type: research

Impact of COVID-19 Pandemic on a Regional Stroke Thrombectomy Service in the United Kingdom
Conclusion: The COVID-19 pandemic has had a negative impact on the stroke admission numbers but not stroke thrombectomy rate, successful recanalization rate, or early neurological outcome. Internal delays actually improved during the COVID-19 pandemic. Further studies should examine the effects of the COVID-19 pandemic on longer term outcome.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 11, 2020 Category: Neurology Source Type: research

Effects of the COVID-19 pandemic on reperfusion therapy for acute ischemic stroke patients in Huizhou City, China
ConclusionDuring the COVID-19 pandemic in 2020, the number of AIS patients receiving reperfusion therapy significantly decreased when compared to the same period in 2019. The patients ’ condition increased severity, ODT increased, and the DNT decreased. DPT was not significant for self-visiting and ambulance patients. Moderate to severe stroke patients were more likely to utilize ambulance services.
Source: Neurological Sciences - January 7, 2021 Category: Neurology Source Type: research