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Cardiac Imaging After Ischemic Stroke or Transient Ischemic Attack
This article summarizes the latest research on this topic and provides an approach to clinical practice to use cardiac imaging after stroke.Recent FindingsEchocardiography remains the primary imaging method for cardiac work-up after stroke. Recent echocardiography studies further demonstrated promising results regarding the prediction of non-permanent atrial fibrillation after ischemic stroke. Cardiac magnetic resonance imaging and computed tomography have been tested for their diagnostic value, in particular in patients with cryptogenic stroke, and can be considered as second line methods, providing complementary informat...
Source: Current Neurology and Neuroscience Reports - June 29, 2020 Category: Neuroscience Source Type: research

Protocol for LASER: A Randomized Evaluation and an Associated Registry of Early Anticoagulation With Edoxaban After Ischemic Stroke in Patients With Atrial Fibrillation
This study will provide data required for a definitive safety/efficacy study sample size power calculation.
Source: Frontiers in Neurology - March 31, 2021 Category: Neurology Source Type: research

Gait speed and spasticity are independently associated with estimated failure load in the distal tibia after stroke: an HR-pQCT study
ConclusionThe paretic distal tibia showed more compromised vBMD, cortical area, cortical thickness, and estimated failure load than the non-paretic tibia. Gait speed and spasticity were independently associated with estimated failure load. As treatment programs focusing on these potentially modifiable stroke-related impairments are feasible to administer, future studies are needed to determine the efficacy of such intervention strategies for improving bone strength in individuals with chronic stroke.
Source: Osteoporosis International - October 12, 2021 Category: Orthopaedics Source Type: research

Thoracic Aortic < sup > 18 < /sup > F-Sodium Fluoride Activity and Ischemic Stroke in Patients With Established Cardiovascular Disease
CONCLUSIONS: In patients with established cardiovascular disease, thoracic aortic 18F-sodium fluoride activity is associated with the progression of atherosclerosis and future ischemic stroke. Arterial 18F-sodium fluoride activity identifies localized areas of atherosclerotic disease activity that are directly linked to disease progression and downstream regional clinical atherothrombotic events. (DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury [DIAMOND], NCT02110303; Study Investigating the Effect of Drugs Used to Treat Osteoporosis on the Progression of Calcific Aortic Stenosis [SALTIRE II], NCT02132026; ...
Source: Atherosclerosis - February 20, 2022 Category: Cardiology Authors: Alexander J Fletcher Yong Y Tew Evangelos Tzolos Shruti S Joshi Jakub Kaczynski Jennifer Nash Samuel Debono Maria Lembo Jacek Kwiecinski Rong Bing Maaz B J Syed Mhairi K Doris Edwin J R van Beek Alistair J Moss William S Jenkins Niki L Walker Nikhil V Jos Source Type: research

The Relationship Between Aortic Arch Calcification and Recurrent Stroke in Patients With Embolic Stroke of Undetermined Source —A Case-Control Study
ConclusionsAortic arch calcification, especially spotty calcification, had a good predictive value for stroke recurrence in patients with ESUS.
Source: Frontiers in Neurology - April 25, 2022 Category: Neurology Source Type: research

Pre- and in-hospital delays in the use of thrombolytic therapy for patients with acute ischemic stroke in rural and urban Egypt
ConclusionThe limited availability of stroke-ready hospitals in rural Egypt leads to delays in stroke management, with subsequent treatment inequality of rural patients with acute stroke.
Source: Frontiers in Neurology - January 20, 2023 Category: Neurology Source Type: research

Clinical features of ischemic stroke in patients with nonvalvular atrial fibrillation combined with intracranial atherosclerotic stenosis
ConclusionNVAF with ICAS ischemic stroke is more likely to occur in older patients. Infarctions occurred mainly in the right cerebral hemisphere. Neurological deficits in NVAF are more severe than those in NVAF combined with ICAS and in simple ICAS ischemic strokes. HsCRP, LEVF, andNTpro-BNP seem to be closely associated with NVAF+ICAS ischemic stroke.
Source: Brain and Behavior - May 2, 2023 Category: Neurology Authors: Ning Wu, Xinli Wang, Shuai Jia, Xiaomei Cui, Yaozhen Wang, Jian Li, Xiaojun Zhang, Yanqiang Wang Tags: ORIGINAL ARTICLE Source Type: research

Comparing 5G mobile stroke unit and emergency medical service in patients acute ischemic stroke eligible for t ‐PA treatment: A prospective, single‐center clinical trial in Ya'an, China
ConclusionsOur findings indicate that 5G MSU care significantly reduces the time from symptom onset to stroke diagnosis and intravenous thrombolysis in patients with AIS, resulting in improved functional outcomes compared to EMS care. As China continues its deployment of 5G technology and other digital infrastructures, the adoption of 5G MSU care on a broader scale may eventually supplant traditional stroke treatment approaches.
Source: Brain and Behavior - August 26, 2023 Category: Neurology Authors: Bo Zheng, Yan Li, Gangfeng Gu, Jian Yang, Junyao Jiang, Zhao Chen, Yang Fan, Sheng Wang, Han Pei, Jian Wang Tags: ORIGINAL ARTICLE Source Type: research

Tissue Window in Stroke Thrombolysis Study (TWIST): A Safety Study.
Conclusions: Patients who awake with their deficits can be safely treated with thrombolysis based upon a tissue window defined by NCCT and CTA/TCD. PMID: 23250122 [PubMed - in process]
Source: The Canadian Journal of Neurological Sciences - January 1, 2013 Category: Neurology Authors: Hill MD, Kenney C, Dzialowski I, Boulanger JM, Demchuk AM, Barber PA, Watson TW, Weir NU, Buchan AM Tags: Can J Neurol Sci Source Type: research

Stroke Mortality And Its Predictors In Nigeria: Results Of A Hospital-Based Study (P2.120)
Conclusion: The 30-day case fatality rate among our stroke patients is high while the independent predictors of this outcome are severity of stroke on admission and presence of complications. Continuing health education of the public on stroke recognition and the need for early hospital presentation is necessary while optimal management of cases in a stroke care unit is advocated in order to improve outcome.Disclosure: Dr. Wahab has nothing to disclose. Dr. Sanya has nothing to disclose. Dr. Ademiluyi has nothing to disclose. Dr. Abiodun has nothing to disclose. Dr. Alaofin has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Wahab, K., Sanya, E., Ademiluyi, B., Abiodun, B., Alaofin, W. Tags: Cerebrovascular Disease and Interventional Neurology: Behavioral, Cognitive, and Miscellaneous Source Type: research

Stroke Mortality And Its Predictors In Nigeria: Results Of A Hospital-Based Study (I10-1.008)
Conclusion: The 30-day case fatality rate among our stroke patients is high while the independent predictors of this outcome are severity of stroke on admission and presence of complications. Continuing health education of the public on stroke recognition and the need for early hospital presentation is necessary while optimal management of cases in a stroke care unit is advocated in order to improve outcome.Disclosure: Dr. Wahab has nothing to disclose. Dr. Sanya has nothing to disclose. Dr. Ademiluyi has nothing to disclose. Dr. Abiodun has nothing to disclose. Dr. Alaofin has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Wahab, K., Sanya, E., Ademiluyi, B., Abiodun, B., Alaofin, W. Tags: The Global Burden of Neurological Diseases Poster Presentations Source Type: research

Prevalence of Ischemic and Hemorrhagic Strokes in Qena Governorate, Egypt: Community-based Study
Conclusions: The overall prevalence rate of stroke is nearly the same as in other Egyptian governorates and is higher than other Arabic countries.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2014 Category: Neurology Authors: Eman M. Khedr, Gharib Fawi, Mohamed Abdela, Talal A. Mohammed, Mohamed A. Ahmed, Noha Abo El-Fetoh, Ahmed F. Zaki Tags: Original Articles Source Type: research

Impact of Atrial Fibrillation and Inadequate Antithrombotic Management on Mortality in Acute Neurovascular Syndrome
Conclusions: Patients with AF have more severe stroke and higher mortality than stroke patients without AF. Adherence to the antithrombotic treatment guidelines for the prevention of AF-related cardioembolic strokes is suboptimal. Further studies are needed to evaluate the impact of current antithrombotic treatment guidelines on mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - August 25, 2014 Category: Neurology Authors: Jukka T. Saarinen, Harri Rusanen, Niko Sillanpää, Heini Huhtala, Heikki Numminen, Irina Elovaara Tags: Original Articles Source Type: research

Multiple Hypointense Vessels on Susceptibility-Weighted Imaging in Acute Ischemic Stroke: Surrogate Marker of Oxygen Extraction Fraction in Penumbra?
Background: Multiple hypointense vessels (MHV) on susceptibility-weighted imaging (SWI) are frequently observed in patients with acute cerebral ischemia, but their implication has not been clearly established. To elucidate the clinical significance of MHV on SWI, we investigated the association of MHV on SWI with clinical data and other MR markers in patients with acute ischemic stroke. Methods: We enrolled acute stroke patients with internal carotid or proximal middle cerebral artery occlusion who underwent MRI including SWI within 3 days from stroke onset. Baseline clinical data were reviewed. Stroke severity was measure...
Source: Cerebrovascular Diseases - November 12, 2014 Category: Neurology Source Type: research