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Total 2417 results found since Jan 2013.

Photoacoustic microscopy reveals the hemodynamic basis of sphingosine 1-phosphate-induced neuroprotection against ischemic stroke
Conclusions: Our results reveal that elevated blood S1P significantly changes cerebral hemodynamics and oxygen metabolism under hypoxia but not normoxia. The improved blood oxygenation and reduced oxygen demand in the hypoxic brain may underlie the neuroprotective effect of S1P against ischemic stroke.
Source: Theranostics - December 7, 2018 Category: Molecular Biology Authors: Rui Cao, Jun Li, Yugesh Kharel, Chenchu Zhang, Emily Morris, Webster L. Santos, Kevin R. Lynch, Zhiyi Zuo, Song Hu Tags: Research Paper Source Type: research

Endovascular treatment of acute ischaemic stroke under conscious sedation: Predictors of poor outcomes
Conclusion: The outcome of patients who underwent endovascular treatment of AIS under CS depends on the mTICI score, NIHSS score and history of previous TIA.
Source: Indian Journal of Anaesthesia - December 10, 2018 Category: Anesthesiology Authors: Umeshkumar Athiraman Arbi Ben Abdallah Akash Kansagra Rene Tempelhoff Source Type: research

Spinal anesthesia-induced hypotension is caused by a decrease in stroke volume in elderly patients.
Conclusion: CO and blood pressure decreased significantly after the onset of SA in elderly patients. This is mainly caused by a decrease in SV and not by a decrease in SVR. There was no difference in CO and blood pressure change between dosages of 10 or 15 mg bupivacaine. PMID: 30881108 [PubMed]
Source: Local and Regional Anesthesia - March 20, 2019 Category: Anesthesiology Tags: Local Reg Anesth Source Type: research

Anesthesiological management in endovascular stroke treatment.
Abstract Early recanalization of the closed cerebral arteries after acute ischemic stroke (AIS) is the only treatment to minimize long-term disability and to reduce the associated morbidity and mortality. For a long time the only proven causal treatment of AIS was intravenous thrombolysis; however, after the publication of a series of randomized prospective studies concerning endovascular mechanical thrombectomy using stent retriever systems after AIS, new guidelines were published. It was found that endovascular treatment (EVT) dramatically improves the outcome of eligible patients. The stent retriever enables ...
Source: Der Anaesthesist - July 18, 2019 Category: Anesthesiology Authors: Theilen HJ, Gerber JC Tags: Anaesthesist Source Type: research

Incidence and impact of stroke following surgery for low-grade gliomas.
CONCLUSIONS: Recurrent surgeries and insular tumor locations are risk factors for intraoperative strokes. Although they do not affect survival, these strokes negatively affect patient activity and performance status, mainly during the first 3 postoperative months, with gradual functional improvement over 1 year. Several intraoperative parameters may suggest the impending development of an infarct. PMID: 31881532 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - December 26, 2019 Category: Neurosurgery Authors: Berger A, Tzarfati G, Costa M, Serafimova M, Korn A, Vendrov I, Alfasi T, Krill D, Aviram D, Ben Moshe S, Kashanian A, Ram Z, Grossman R Tags: J Neurosurg Source Type: research

Defining and Managing Pain in Stroke and Traumatic Brain Injury Research.
Abstract Neurologic conditions such as stroke and traumatic brain injury are challenging conditions to study in humans. Animal models are necessary to uncover disease processes and develop novel therapies. When attempting to model these or other neurologic diseases, the accompanying anesthesia and analgesia create variables that are not part of the onset of the clinical disease in the human population but are critical components of the postinjury care both in humans and animals. To maximize model validity, researchers must consider whether the disease process or a novel therapy is being studied. Damage to the neur...
Source: Comparative Medicine - December 19, 2019 Category: Zoology Authors: Larson CM, Wilcox GL, Fairbanks CA Tags: Comp Med Source Type: research

Single mean arterial blood pressure drops during stroke thrombectomy under general anaesthesia are associated with poor outcome
ConclusionsFor patients undergoing MT under GA, single MAP drops  <  60 mmHg are independently related to unfavourable 3-month outcome. Therefore, every effort should be made to prevent periinterventional hypotensive episodes, especially below this threshold.
Source: Journal of Neurology - January 17, 2020 Category: Neurology Source Type: research

Hemodynamic Changes via the Lung Recruitment Maneuver Can Predict Fluid Responsiveness in Stroke Volume and Arterial Pressure During One-Lung Ventilation
CONCLUSIONS: ΔSVRM and ΔMAPRM could predict hemodynamic responses after volume expansion during OLV.PMID:33687175 | DOI:10.1213/ANE.0000000000005375
Source: Anesthesia and Analgesia - March 9, 2021 Category: Anesthesiology Authors: Aya Kimura Koichi Suehiro Takashi Juri Yohei Fujimoto Hisako Yoshida Katsuaki Tanaka Takashi Mori Kiyonobu Nishikawa Source Type: research

Management of Endovascular Treatment for Acute Ischemic Stroke During the COVID-19 Pandemic at a Single Institution in Beijing, China: A Brief Report
Background: The coronavirus disease (COVID-19) pandemic is currently a major challenge for health care systems around the world. For a time-sensitive emergency such as acute ischemic stroke (AIS), streamlined workflow times are essential to ensure good clinical outcomes. Methods: The aim of this single-center, retrospective, observational study was to describe changes in stroke workflow patterns and clinical care during the COVID-19 pandemic. Data from AIS patients undergoing emergent endovascular treatment (EVT) between 23 January and 8 April 2020 were retrospectively collected and compared with data from patie...
Source: Journal of Neurosurgical Anesthesiology - June 18, 2021 Category: Anesthesiology Tags: Short Reports Source Type: research

Effect of Leg Lift on Stroke Volume Index in Children 11-17 Years Old Before and After Induction of General Anesthesia
CONCLUSIONS: 96% of normal 11 to 17-year-old children were fluid responsive while awake and 79% after induction of general anesthesia.PMID:34233078 | DOI:10.1111/pan.14254
Source: Paediatric Anaesthesia - July 7, 2021 Category: Anesthesiology Authors: Andrew F Stasic Bethany J Wolf Stephen F Dierdorf Nicole D Horn Korey Vecchione Brian N Egan Michael A Acquaviva Source Type: research

New-onset Atrial Fibrillation after Cardiac Surgery is a Significant Risk Factor for Long-term Stroke: An 8-Year Prospective Cohort Study
This study sought to determine the incidence and significance of new-onset atrial fibrillation as a risk factor for long-term stroke and mortality after cardiac surgery.Design: A prospective cohort study.Setting: 2 large tertiary public hospitalsParticipants: The study comprised 3008 patients who underwent coronary artery bypass grafting and/or valve surgery from 2008 to 2012.Interventions: None.Measurements and Main Results: new-onset atrial fibrillation was analysed as a risk factor for postoperative stroke using a multivariable logistic regression model following adjustment for potential confounders.
Source: Journal of Cardiothoracic and Vascular Anesthesia - July 8, 2021 Category: Anesthesiology Authors: Kevin K.P. Wang, Weiling Liu, Sophia T.H. Chew, Lian Kah Ti, Liang Shen Source Type: research

Effect of Leg Lift on Stroke Volume Index in Children 11-17 Years Old Before and After Induction of General Anesthesia
CONCLUSIONS: 96% of normal 11 to 17-year-old children were fluid responsive while awake and 79% after induction of general anesthesia.PMID:34233078 | DOI:10.1111/pan.14254
Source: Paediatric Anaesthesia - July 7, 2021 Category: Anesthesiology Authors: Andrew F Stasic Bethany J Wolf Stephen F Dierdorf Nicole D Horn Korey Vecchione Brian N Egan Michael A Acquaviva Source Type: research