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Total 2417 results found since Jan 2013.

Stroke Neurologist's Perspective on the New Endovascular Trials Understanding and Applying the Endovascular Trials
In conclusion, stroke teams, including practicing neurologists caring for patients with stroke should now provide the option for intra-arterial thrombectomy for a subset of patients with acute stroke.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Grotta, J. C., Hacke, W. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Understanding and Applying the Endovascular Trials Source Type: research

General Anesthesia Versus Conscious Sedation for Endovascular Treatment of Acute Ischemic Stroke Clinical Sciences
Conclusions—In endovascular treatment for acute ischemic stroke, no difference was found between general anesthesia and conscious sedation in neurological outcome 3 months after stroke.Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT01872884.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Pia Lowhagen Henden, Alexandros Rentzos, Jan–Erik Karlsson, Lars Rosengren, Birgitta Leiram, Henrik Sundeman, Dennis Dunker, Kunigunde Schnabel, Gunnar Wikholm, Mikael Hellstrom, Sven–Erik Ricksten Tags: Revascularization, Ischemic Stroke Original Contributions Source Type: research

Hypotension During Endovascular Treatment of Ischemic Stroke Is a Risk Factor for Poor Neurological Outcome Brief Reports
Conclusions— Profound intraprocedural hypotension is an independent predictor for poor neurological outcome in patients with acute ischemic stroke undergoing endovascular therapy in general anesthesia.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Lowhagen Henden, P., Rentzos, A., Karlsson, J.-E., Rosengren, L., Sundeman, H., Reinsfelt, B., Ricksten, S.-E. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Other Stroke Treatment - Surgical Brief Reports Source Type: research

Optimal Workflow and Process-Based Performance Measures for Endovascular Therapy in Acute Ischemic Stroke: Analysis of the Solitaire FR Thrombectomy for Acute Revascularization Study Clinical Sciences
Conclusions— Interval times in the STAR study reflect current intra-arterial therapy for patients with acute ischemic stroke. Improving workflow metrics can further improve clinical outcome. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01327989.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Menon, B. K., Almekhlafi, M. A., Pereira, V. M., Gralla, J., Bonafe, A., Davalos, A., Chapot, R., Goyal, M., on behalf of the STAR Study Investigators Tags: Acute Stroke Syndromes, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Anesthesia Technique and Outcomes of Mechanical Thrombectomy in Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions—Using a comprehensive all-payer cohort of acute ischemic stroke patients undergoing mechanical thrombectomy in New York State, we identified an association of general anesthesia with increased case-fatality and length of stay. These considerations should be taken into account when standardizing acute stroke care.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Kimon Bekelis, Symeon Missios, Todd A. MacKenzie, Stavropoula Tjoumakaris, Pascal Jabbour Tags: Revascularization, Ischemic Stroke Original Contributions Source Type: research

Anesthesia-Related Outcomes for Endovascular Stroke Revascularization Clinical Sciences
Conclusions—Acute ischemic stroke patients undergoing intra-arterial therapy may have worse outcomes when treated with GA as compared with conscious sedation/local anesthesia. However, major limitations of current evidence (ie, retrospective studies and selection bias) indicate a need for adequately powered, multicenter randomized controlled trials to answer this question.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Waleed Brinjikji, Jeffrey Pasternak, Mohammad H. Murad, Harry J. Cloft, Tasha L. Welch, David F. Kallmes, Alejandro A. Rabinstein Tags: Revascularization, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Predictors of Good Outcome After Endovascular Therapy for Vertebrobasilar Occlusion Stroke Clinical Sciences
Background and Purpose—Endovascular therapy is increasingly used in acute ischemic stroke treatment and is now considered the gold standard approach for selected patient populations. Prior studies have demonstrated that eventual patient outcomes depend on both patient-specific factors and procedural considerations. However, these factors remain unclear for acute basilar artery occlusion stroke. We sought to determine prognostic factors of good outcome in acute posterior circulation large vessel occlusion strokes treated with endovascular therapy.Methods—We reviewed our prospectively collected endovascular databases at ...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Mehdi Bouslama, Diogo C. Haussen, Amin Aghaebrahim, Jonathan A. Grossberg, Gregory Walker, Srikant Rangaraju, Anat Horev, Michael R. Frankel, Raul G. Nogueira, Tudor G. Jovin, Ashutosh P. Jadhav Tags: Quality and Outcomes, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Type of Anesthesia and Differences in Clinical Outcome After Intra-Arterial Treatment for Ischemic Stroke Clinical Sciences
Conclusions— Our study suggests that patients with AIS of the anterior circulation undergoing IAT without GA have a higher probability of good clinical outcome compared with patients treated with general anesthesia.
Source: Stroke - April 27, 2015 Category: Neurology Authors: van den Berg, L. A., Koelman, D. L. H., Berkhemer, O. A., Rozeman, A. D., Fransen, P. S. S., Beumer, D., Dippel, D. W., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Brouwer, P. A., Jenniskens, S., Boiten, J., Lycklama a Nijeholt, G. A., Vos Tags: Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Association of Blood Pressure With Short- and Long-Term Functional Outcome After Stroke Thrombectomy Clinical Sciences
This study aims to assess the association of BP changes during general anesthesia versus conscious sedation with functional outcome after mechanical thrombectomy.Methods—SIESTA (Sedation vs Intubation for Endovascular Stroke Treatment) was a monocentric randomized trial of general anesthesia versus conscious sedation during mechanical thrombectomy involving BP target protocols. In this post hoc analysis, BP measurements were divided into 4 phases: preintervention, prerecanalization, postrecanalization, and postintervention. We examined the association between BP and functional outcomes (defined by improvement of 24-hour ...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Silvia Schonenberger, Lorenz Uhlmann, Matthias Ungerer, Johannes Pfaff, Simon Nagel, Christina Klose, Martin Bendszus, Wolfgang Wick, Peter A. Ringleb, Meinhard Kieser, Markus A. Mohlenbruch, Julian Bosel Tags: Ischemic Stroke Original Contributions Source Type: research

Magnetic Resonance Imaging Selection for Endovascular Stroke Therapy Clinical Sciences
Conclusions—Workflow in GOLIATH demonstrates that magnetic resonance imaging selection for endovascular therapy can be accomplished rapidly and within a similar time frame as computed tomography-based selection.Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT02317237.
Source: Stroke - May 25, 2018 Category: Neurology Authors: Claus Z. Simonsen, Albert J. Yoo, Mads Rasmussen, Kristina E. Sorensen, Thabele Leslie–Mazwi, Grethe Andersen, Leif H. Sorensen Tags: Magnetic Resonance Imaging (MRI), Revascularization, Ischemic Stroke Original Contributions Source Type: research

Clinical diagnostic tools for screening of perioperative stroke in general surgery: a systematic review
Perioperative stroke is a devastating complication that carries high mortality and functional disability. Unfortunately, residual anaesthesia and analgesia may obscure important warning signs and may lead to a delay in the assessment and treatment of major stroke after surgery. The purpose of this review is to examine the utility of existing stroke scales, for the recognition of perioperative stroke in the general surgical population. A total of 21 stroke scales have been described in the literature. Diagnostic performance was reported in 17 scales. The majority of the stroke scales were designed to evaluate current neurol...
Source: British Journal of Anaesthesia - February 10, 2016 Category: Anesthesiology Authors: Sun, Z., Yue, Y., Leung, C. C. H., Chan, M. T. V., Gelb, A. W., on behalf of the Study Group for Perioperative Stroke In China (POSIC), on behalf of the Study Group for Perioperative Stroke In China (POSIC), Wu, Yue, Sun, Guo, Ding, Wang, Tian, Mei, Yao, Tags: Review Articles Source Type: research

Drivers of Costs Associated With Reperfusion Therapy in Acute Stroke: The Interventional Management of Stroke III Trial Clinical Sciences
Conclusions— Minimizing the time to start of intravenous tPA and decreasing the use of routine general anesthesia may improve the cost-effectiveness of medical and endovascular therapy for acute stroke. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00359424.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Simpson, K. N., Simpson, A. N., Mauldin, P. D., Hill, M. D., Yeatts, S. D., Spilker, J. A., Foster, L. D., Khatri, P., Martin, R., Jauch, E. C., Kleindorfer, D., Palesch, Y. Y., Broderick, J. P., for the IMS III Investigators Tags: Thrombolysis Clinical Sciences Source Type: research

Intraoperative Completion Studies, Local Anesthesia, and Antiplatelet Medication Are Associated With Lower Risk in Carotid Endarterectomy Clinical Sciences
Conclusions—Local anesthesia, patch plasty compared with primary closure, intraoperative completion studies by duplex ultrasound or angiography, and perioperative antiplatelet medication were independently associated with lower in-hospital stroke or death rates after carotid endarterectomy.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Christoph Knappich, Andreas Kuehnl, Pavlos Tsantilas, Sofie Schmid, Thorben Breitkreuz, Michael Kallmayer, Alexander Zimmermann, Hans-Henning Eckstein Tags: Clinical Studies, Revascularization, Quality and Outcomes, Cerebrovascular Disease/Stroke, Atherosclerosis Original Contributions Source Type: research

Sedation vs. Intubation for Endovascular Stroke TreAtment (SIESTA) – a randomized monocentric trial
ConclusionThe aims of this study are to prospectively clarify whether the non‐intubated state of conscious sedation is feasible, safe, and superior with regard to early neurological improvement compared to the intubated state of general anesthesia in patients receiving acute endovascular stroke treatment.
Source: International Journal of Stroke - April 12, 2015 Category: Neurology Authors: Silvia Schönenberger, Markus Möhlenbruch, Johannes Pfaff, Sibu Mundiyanapurath, Meinhard Kieser, Martin Bendszus, Werner Hacke, Julian Bösel Tags: Protocol Source Type: research

Predictive value of transcranial evoked potentials during mechanical endovascular therapy for acute ischaemic stroke: a feasibility study
Conclusions MEPs and SSEPs are safe and feasible methods of real-time monitoring of reperfusion success with respect to functional outcome during MET for acute ischaemic stroke.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 12, 2016 Category: Neurosurgery Authors: Shiban, E., Wunderlich, S., Kreiser, K., Lehmberg, J., Hemmer, B., Prothmann, S., Zimmer, C., Meyer, B., Ringel, F. Tags: Immunology (including allergy), Stroke Cerebrovascular disease Source Type: research