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Drug: Beta-Blockers

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Total 494 results found since Jan 2013.

{beta}-Blockers, Pneumonia, and Outcome After Ischemic Stroke: Evidence From Virtual International Stroke Trials Archive Clinical Sciences
Conclusions— In this large nonrandomized comparison, on-stroke BB was associated with reduced mortality. Prestroke and on-stroke BB were inversely associated with incidence of nosocomial pneumonia. Randomized trials investigating the potential of β-blockade in acute stroke may be warranted.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Sykora, M., Siarnik, P., Diedler, J., for the VISTA Acute Collaborators, VISTA Acute Collaborators, Lees, Alexandrov, Bath, Bluhmki, Bornstein, Claesson, Davis, Donnan, Diener, Fisher, Ginsberg, Gregson, Grotta, Hacke, Hennerici, Hommel, Kaste, Lyden, Mar Tags: Acute Cerebral Infarction, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Antihypertensive Drug Use, Blood Pressure Variability, and Incident Stroke Risk in Older Adults: Three-City Cohort Study Clinical Sciences
Conclusions— The angiotensin receptor blocker and β-blocker drug classes were associated with incident stroke and ischemic stroke in older adults. BPV was generally not associated with incident stroke.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Tully, P. J., Debette, S., Dartigues, J.-F., Helmer, C., Artero, S., Tzourio, C. Tags: High Blood Pressure, Hypertension, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Beta-blockers are not associated with stroke severity and outcome in hypertensive patients: data from a national stroke registry
Lowering blood pressure (BP) with beta-blockers is less effective in reducing the risk of stroke than with other agents. However, studies on associations between use of beta-blockers and stroke severity are inconclusive. We assessed the association between pre-stroke use of beta-blockers and stroke severity, disability and death in a large prospective national registry of hospitalized hypertensive patients with acute stroke.
Source: Journal of the American Society of Hypertension - March 31, 2016 Category: Cardiology Authors: Ehud Grossman, David Tanne, Silvia Koton Tags: Stroke Source Type: research

Does Prior Use of Beta Blockers Affect Functional Outcomes Post Ischemic Stroke Endovascular Intervention? (P5.296)
Conclusions:Prior use of beta blockers did not lead to better functional outcomes (MRS ≤2) in acute ischemic stroke patients undergoing EVI. Findings should be further confirmed in larger population.Disclosure: Dr. Albadareen has nothing to disclose. Dr. Gronseth has received personal compensation in an editorial capacity for Neurology. Dr. Gronseth has received research support from the American Academy of Neurology. Dr. Mittal has nothing to disclose. Dr. Sharrock has nothing to disclose. Dr. Keshary has nothing to disclose. Dr. Abraham has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Albadareen, R., Gronseth, G., Mittal, M., Sharrock, M., Keshary, S., Abraham, M. Tags: Stroke Recovery and Rehabilitation Source Type: research

Fitness and cognition in the elderly: The Austrian Stroke Prevention Study
Conclusions: Higher Vo2max is associated with better global cognitive function and with better performance in the cognitive domains of memory, executive function, and motor skills in the middle-aged and elderly. The association is not mediated by the presence of white matter lesions, lacunes, and brain atrophy.
Source: Neurology - February 1, 2016 Category: Neurology Authors: Freudenberger, P., Petrovic, K., Sen, A., Toglhofer, A. M., Fixa, A., Hofer, E., Perl, S., Zweiker, R., Seshadri, S., Schmidt, R., Schmidt, H. Tags: MRI, All Cerebrovascular disease/Stroke, Cognitive aging, Cohort studies ARTICLE Source Type: research

Postreperfusion Blood Pressure Variability After Endovascular Thrombectomy Affects Outcomes in Acute Ischemic Stroke Patients With Poor Collateral Circulation
Conclusion: Postreperfusion BP management by decreasing BPV may have influence on improving clinical outcome in cases of poor collateral circulation among patients achieving successful recanalization after ERT. Introduction Endovascular recanalization therapy (ERT) has been adopted as standard stroke care in patients with acute ischemic stroke (1–6). Time to recanalization and degree of recanalization are the most important predictors of clinical outcomes after ERT (7). Before recanalization, an effort to reduce the time from symptom onset to reperfusion is critical for penumbral salvage. After recanalization...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Are beta blockers effective in preventing stroke associated infections? - a systematic review and meta-analysis
CONCLUSION: Due to the lack of robust evidence, this meta-analysis may not support the preventive effect of beta blockers on stroke associated infection. But beta blockers treatment may be associated with development of post-stroke urinary tract infection and stroke associated pneumonia in some stroke patients.PMID:35585021 | DOI:10.18632/aging.204086
Source: Aging - May 18, 2022 Category: Biomedical Science Authors: Li Yang Xiang Wenping Zhang Jinfeng Pang Jiangxia Wang Jingbo Wang Baojun Source Type: research

Adherence to antihypertensive therapy prior to the first presentation of stroke in hypertensive adults: population-based study
Conclusion These data suggest that poor adherence to antihypertensive therapy substantially increases near- and long-term risk of stroke among hypertensive patients.
Source: European Heart Journal - October 7, 2013 Category: Cardiology Authors: Herttua, K., Tabak, A. G., Martikainen, P., Vahtera, J., Kivimaki, M. Tags: Hypertension Source Type: research

Interventions for deliberately altering blood pressure in acute stroke.
CONCLUSIONS: There is insufficient evidence that lowering blood pressure during the acute phase of stroke improves functional outcome. It is reasonable to withhold blood pressure-lowering drugs until patients are medically and neurologically stable, and have suitable oral or enteral access, after which drugs can than be reintroduced. In people with acute stroke, CCBs, ACEI, ARA, beta blockers and NO donors each lower blood pressure while phenylephrine probably increases blood pressure. Further trials are needed to identify which people are most likely to benefit from early treatment, in particular whether treatment started...
Source: Cochrane Database of Systematic Reviews - October 28, 2014 Category: Journals (General) Authors: Bath PM, Krishnan K Tags: Cochrane Database Syst Rev Source Type: research

Beta-blockers for preventing stroke recurrence.
CONCLUSIONS: To date, no available evidence supports the routine use of beta-blockers for secondary prevention after stroke or TIA. More studies with larger samples are needed. PMID: 25317988 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - October 15, 2014 Category: Journals (General) Authors: De Lima LG, Saconato H, Atallah AN, da Silva EM Tags: Cochrane Database Syst Rev Source Type: research

Get Rid of Toxins to Reduce Risk of Stroke
Effects of Toxins I’ve been warning you about the toxins in our environment for years. They cause inflammation… They make you gain weight… They cause you to feel fatigued… Our exposure to them starts before we’re even born. One study found 287 chemicals and toxins in the blood of newborn babies.1 It’s shocking. What is in the air we breathe? We breathe in toxins and air pollutants every day. Carbon dioxide, lead, nitrogen oxide, sulfur dioxide, and particulate matter (PM). Causes of Stroke Now, a new study reveals that air pollution is responsible for as many as one-third of all strokes.2 That’...
Source: Al Sears, MD Natural Remedies - July 15, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news

Pre-Stroke Use of Beta-Blockers Does Not Lower Post-Stroke Infection Rate: An Exploratory Analysis of the Preventive Antibiotics in Stroke Study
This study is aimed at investigating the association between BB treatment at baseline and post-stroke infection in the Preventive Antibiotics in Stroke Study (PASS), a prospective clinical trial.Methods: We performed an exploratory analysis in PASS, 2,538 patients with acute phase of stroke (24 h after onset) were randomized to ceftriaxone (intravenous, 2 g per day for 4 days) in addition to stroke unit care, or standard stroke unit care without preventive antibiotic treatment. All clinical data, including use of BBs, was prospectively collected. Infection was diagnosed by the treating physician, and independently by an ex...
Source: Cerebrovascular Diseases - October 4, 2016 Category: Neurology Source Type: research

Prestroke treatment with beta-blockers for hypertension is not associated with severity and poor outcome in patients with ischemic stroke: data from a national stroke registry
Background: Beta-blockers are not recommended as the initial therapy for hypertension. Reports on associations between use of beta-blockers and stroke severity are inconclusive. We assessed associations between prestroke use of beta-blockers and stroke severity, poststroke disability and death in a large group of hypertensive patients hospitalized with acute ischemic stroke. Methods: All 3915 patients with ischemic stroke, treated prestroke for hypertension and registered in the National Acute Stroke ISraeli, were included. Treatment for hypertension was classified by medication type (beta-blockers, diuretics, calcium ant...
Source: Journal of Hypertension - March 2, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research

Effect of Amlodipine in Stroke and Myocardial infarction: A Systematic Review and Meta-analysis
ConclusionIn the pooled analysis of data from 12 randomised controlled trials and one double-blinded cohort study measuring the effect of CCBs, we found that the CCB amlodipine reduced the risk of stroke and MI in hypertensive patients. Superior results for amlodipine were found in ten of the 13 studies included in this meta-analysis.
Source: Cardiology and Therapy - September 4, 2021 Category: Cardiology Source Type: research

Cardiorespiratory fitness in individuals post-stroke: reference values and determinants
CONCLUSIONS: Population specific reference values of cardiorespiratory fitness for individuals post-stroke corrected for age and sex were presented. These can give individuals post-stroke and health-care providers insight in their cardiorespiratory fitness compared to their peers. Furthermore, they can be used to determine the potential necessity for cardiorespiratory fitness training as part of the rehabilitation program for an individual post-stroke to enhance their fitness, functioning and health. Especially, individuals post-stroke with more mobility limitations and beta-blocker use are at a higher risk of low cardiore...
Source: Health Physics - May 12, 2023 Category: Physics Authors: Ilse J Blokland Floor P Groot Nadine H G Logt Prof Dr Coen A M Bennekom Dr Jos J de Koning Prof Dr Jaap H van Dieen Prof Dr Han Houdijk Source Type: research