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Total 31 results found since Jan 2013.

Low-cost alternatives for the management of acute ischemic stroke in low and middle-income countries
Ann Med Surg (Lond). 2021 Oct 21;72:102969. doi: 10.1016/j.amsu.2021.102969. eCollection 2021 Dec.ABSTRACTAcute ischemic stroke (AIS) patients arriving within a suitable time frame are treated with recanalization therapy i.e. intravenous thrombolysis (IVT) with alteplase and/or mechanical thrombectomy (MT). IVT with alteplase is indicated in AIS patients presenting within 4.5 hours of onset regardless of vascular territory involved. MT is indicated in AIS patients presenting within 24 hours of onset with large vessel occlusion in the anterior circulation. However, MT is ludicrously expensive and requires exorbitant setup, ...
Source: Annals of Medicine - January 7, 2022 Category: Internal Medicine Authors: Gaurav Nepal Jayant Kumar Yadav Siddhartha Bhandari Jeevan Gautam Bikram Prasad Gajurel Source Type: research

Content validity of the Brief and Comprehensive ICF Core Sets for common disabling conditions in a developing country
The International Classification of Functioning, Disability and Health (ICF) features associated tools, the Brief and Comprehensive ICF Core Sets. These are designed to be universally applicable, but have limited evidence of content validity (i.e. comprehensiveness and relevance) in low income, non-Western countries. In this cross-sectional study, we aimed to assess the content validity of the ICF Core Sets in Nepal. We interviewed 161 participants with stroke, spinal cord injury (SCI), chronic obstructive pulmonary disease (COPD), and musculoskeletal conditions and asked them to identify activities they had difficulty per...
Source: International Journal of Rehabilitation Research - May 20, 2021 Category: Rehabilitation Tags: Original Articles Source Type: research

Cells to Society: Year of the Nurse / Global Impact
This study establishes baseline sociodemographic and clinical characteristics of hospitalized patients in Nepal who were experiencing heart failure.     Read more   Maternal Health ...
Source: Johns Hopkins University and Health Systems Archive - February 6, 2020 Category: Nursing Source Type: news

Radioimaging and Demographic Profiles of Patients with Spontaneous Intracerebral Hemorrhage: A Need for the Pragmatic Referral System
Adv Exp Med Biol. 2021 Nov 14. doi: 10.1007/5584_2021_662. Online ahead of print.ABSTRACTReferring patients with severe medical conditions, like brain stroke, from small or rural hospitals to tertiary care centers is often overexploited leading to a kind of defensive medicine. The issue of a patient referral system remains unaddressed in Nepal. In this article, we investigated the legitimacy of referring patients with spontaneous intracranial hemorrhage (ICH) from country peripheral hospitals to the leading tertiary neurological center in Nepal. We found that 81 out of the 130 ICH patients reviewed in the study were referr...
Source: Advances in Experimental Medicine and Biology - November 13, 2021 Category: Research Authors: Sunil Munakomi Source Type: research

The Economic Costs of Cardiovascular Disease, Diabetes Mellitus, and Associated Complications in South Asia: A Systematic Review
Conclusions Marked increases in costs have been identified when complications of these chronic diseases occur, underlining the importance of secondary prevention approaches in disease management in South Asia. Higher quality studies, especially those that include longitudinal costs, are required to establish more robust cost estimates.
Source: Value in Health Regional Issues - July 4, 2017 Category: International Medicine & Public Health Source Type: research

Population History and Altitude-Related Adaptation in the Sherpa
The first ascent of Mount Everest by Tenzing Norgay and Sir Edmund Hillary in 1953 brought global attention to the Sherpa people and human performance at altitude. The Sherpa inhabit the Khumbu Valley of Nepal, and are descendants of a population that has resided continuously on the Tibetan plateau for the past ~25,000 to 40,000 years. The long exposure of the Sherpa to an inhospitable environment has driven genetic selection and produced distinct adaptive phenotypes. This review summarizes the population history of the Sherpa and their physiological and genetic adaptation to hypoxia. Genome-wide studies have identified ro...
Source: Frontiers in Physiology - August 27, 2019 Category: Physiology Source Type: research

Endovascular management of acute ischaemic stroke in Nepal
Publication date: May 2020Source: The Lancet Global Health, Volume 8, Issue 5Author(s): Subash Phuyal, Raju Poudel, Gentle S Shrestha, Kapil Dawadi, Vivek K Rauniyar, Lekhjung Thapa, Rupendra B Adhikari, Amit Thapa, Gopal Sedain, Subhash P Acharya, Pankaj Jalan, Chakra R Pandey
Source: The Lancet Global Health - April 29, 2020 Category: International Medicine & Public Health Source Type: research

Polyphenolic-Rich Compounds From Dillenia pentagyna (Roxb.) Attenuates the Doxorubicin-Induced Cardiotoxicity: A High-Frequency Ultrasonography Assisted Approach
Cardiovascular complications are the foremost concern in patients undergoing anticancer therapy. There is an unmet need to address the problems arising from the drug-induced toxicity for the long-term benefit of the patients undergoing chemotherapy. Alternative medicines are gaining their prosperity in addressing the various drug-induced organ toxicity. Dillenia pentagyna Roxb (DP) is an ethnomedicinal plant rich in flavonoids and phenolic contents. In India & Nepal, DP is a common ingredient of traditional medicines used to treat multiple ailments like inflammation, cancer, and diabetes. However, its protective role a...
Source: Frontiers in Pharmacology - May 17, 2021 Category: Drugs & Pharmacology Source Type: research

Estimation of mean population salt intakes using spot urine samples and associations with body mass index, hypertension, raised blood sugar and hypercholesterolemia: Findings from STEPS Survey 2019, Nepal
by Saroj Bhattarai, Bihungum Bista, Binod Kumar Yadav, Pradip Gynawali, Anil Poudyal, Anjani Kumar Jha, Meghnath Dhimal BackgroundHigh dietary salt intake is recognized as a risk factor for several non-communicable diseases (NCDs), in particular cardiovascular diseases (CVDs), including heart attack and stroke. Accurate measurement of population level salt intake is essential for setting targeted goals and plans for salt reduction strategies. We used a spot urine sample to estimate the mean population salt intake in Nepal and evaluated the association of salt intake with excess weight, hypertension, raised blood sugar and ...
Source: PLoS One - April 12, 2022 Category: Biomedical Science Authors: Saroj Bhattarai Source Type: research

UN Aims at People-Centered Governance in a Post-Pandemic World
A rescued boat woman and her two children eat some welcome food at a centre in Kuala Cangkoi, Indonesia. The UN urges 'people-centred' approach to migrants and refugees in Southeast Asia. Credit: UNHCRBy Simone GalimbertiKATHMANDU, Nepal, Apr 29 2022 (IPS) The recently disseminated Zero Draft Ministerial Declaration of the High-Level Political Forum on Sustainable Development (HLPF)– the main UN event to track the member states’ progress to achieve the Agenda 2030 slated to be held in the first half of July– is a disappointment. For all its comprehensiveness, the document neglected to mention one of the most...
Source: IPS Inter Press Service - Health - April 29, 2022 Category: International Medicine & Public Health Authors: Simone Galimberti Tags: COVID-19 Development & Aid Featured Food and Agriculture Global Global Governance Headlines Poverty & SDGs TerraViva United Nations IPS UN Bureau Source Type: news

The Report of Lightning in Himalayan Locale
This report points at analyzing the varieties of lightning inside and over a long time from January 2011 to present. For this report, the information was taken from the Disaster Risk Reduction (DRR) portal of the Ministry of Home Affairs (MOHA). The investigation indicated that there was no lightning occasion in November, and the lightning stroke density was higher in the premonsoon period, and the number of harmed individuals was almost three times the number of individuals passing due to the lightning.PMID:37398914 | PMC:PMC10310457 | DOI:10.1155/2023/1888382
Source: The Scientific World Journal - July 3, 2023 Category: Science Authors: Pitri Bhakta Adhikari Source Type: research