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Total 31 results found since Jan 2013.

Prevalence of Stroke and Stroke Risk Factors in a South-Western Community of Nepal
The global burden of stroke in 2016 suggests that stroke is associated with approximately one million deaths and 22 million disability-adjusted life-years (DALYs) in South Asia, of which nearly 15,000 deaths and 330,000 DALYs occurred in Nepal.1 Stroke incurs a substantial economic burden to the national healthcare system2 and is often unaffordable to low-income families, particularly for those bearing out-of-pocket expenses for all the treatment costs.
Source: Journal of Stroke and Cerebrovascular Diseases - March 13, 2021 Category: Neurology Authors: Lekhjung Thapa, Shakti Shrestha, Rashmi Kandu, Mahesh Raj Ghimire, Sulochana Ghimire, Navin Kumar Chaudhary, Bishnu Pahari, Suman Bhattarai, Ghanshyam Kharel, Raju Paudel, Pankaj Jalan, Avinash Chandra, Subash Phuyal, Bhojraj Adhikari, Nirmal Aryal, Om P Source Type: research

Demographic Characteristics and Prognostic Factors in Acute Ischemic Stroke in a Tertiary Care Hospital in Nepal (P1.073)
Conclusions: The factors that are independently associated with functional status at one month after acute ischemic stroke are the age of the patient at the time of stroke and the baseline neurological status as measured by the National Institute of Health Stroke Scale score. Study Supported by: Not applicableDisclosure: Dr. Gajurel has nothing to disclose. Dr. Oli has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Gajurel, B., Oli, K. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Association between Lys198Asn polymorphism of endothelin ‐1 gene and ischemic stroke: A meta‐analysis
ConclusionsThe present meta ‐analysis suggests that Lys198Asn polymorphism of EDN1 gene is associated with an increased risk for ischemic stroke.
Source: Brain and Behavior - September 29, 2019 Category: Neurology Authors: Gaurav Nepal, Rajeev Ojha, Hari Prasad Dulal, Binod Kumar Yadav Tags: ORIGINAL RESEARCH Source Type: research

Association between K469E polymorphism of ICAM ‐1 gene and susceptibility of ischemic stroke: An updated meta‐analysis
ConclusionK469E polymorphism of ICAM ‐1 gene might be a risk factor for ischemic stroke in Caucasians, which suggested that K469E polymorphism might help in early identification of those at risk and help in primary prevention of ischemic stroke.
Source: Molecular Genetics & Genomic Medicine - June 2, 2019 Category: Genetics & Stem Cells Authors: Gaurav Nepal, Jayant Kumar Yadav, YuHui Kong Tags: ORIGINAL ARTICLE Source Type: research

Are digital social media campaigns the key to raise stroke awareness in low-and middle-income countries? A study of feasibility and cost-effectiveness in Nepal
This study aims to (a) explore the feasibility of a social media-based stroke awareness campaign in Nepal using a cost-benefit analysis and (b) identify best practices for social media health education campaigns. MethodsWe performed a stroke awareness campaign over a period of 6 months as part of a Stroke Project in Nepal on four social media platforms (Facebook, Instagram, Twitter, TikTok) with organic traffic and paid advertisements. Adapted material based on the World Stroke Day Campaign and specifically created videos for TikTok were used. Performance of the campaign was analyzed with established quantitative social me...
Source: PLoS One - September 8, 2023 Category: Biomedical Science Authors: Christine Tunkl Source Type: research

Multicentre registration of wake-up stroke in China (MCRWUSC): a protocol for a prospective, multicentre, registry-based cohort study
This study is approved by the ethics committee of Shanghai Pudong Hospital (Shanghai, China) and rest of all participating centres. The findings will be disseminated through peer-reviewed publications and conference presentations. PROSPERO registration number ChiCTR2100049133.
Source: BMJ Open - November 10, 2022 Category: General Medicine Authors: Zhang, Z., Yang, H., Tu, Z., Nepal, G., Ojha, R., Xi, Y., Qiao, J., Hu, M., Li, C., Lin, F., Zhou, L., Jin, P., Hou, S. Tags: Open access, Neurology Source Type: research

An opportunity to improve Acute Ischemic Stroke care in the South Asian region through telestroke services
Ann Med Surg (Lond). 2021 Nov 25;72:103115. doi: 10.1016/j.amsu.2021.103115. eCollection 2021 Dec.ABSTRACTThe South Asian region accounts for more than 40% of the stroke burden of the developing world and is the highest contributor to global stroke mortality. Despite proven treatment guidelines, the limited number of neurologists, the number of dedicated stroke centers and the fact that most of these facilities are urban-centric renders poor access to thrombolysis in this region, especially in the rural areas. Studies have shown that thrombolysis using telestroke services are comparable to face-to-face thrombolysis. Telest...
Source: Annals of Medicine - December 10, 2021 Category: Internal Medicine Authors: Jayant Kumar Yadav Gaurav Nepal Yow Ka Shing Rohit Raman Banerji Bikram Prasad Gajurel Source Type: research

Role of female community health volunteers in ischemic stroke prevention, identification, referral and rehabilitation in Nepal
Ann Med Surg (Lond). 2021 Oct 8;72:102893. doi: 10.1016/j.amsu.2021.102893. eCollection 2021 Dec.ABSTRACTFor the past three decades, female community health volunteers (FCHVs) have been at the forefront of Nepal's health map and have contributed significantly to its improving health indicators such as maternal mortality rate and infant mortality rate. Given the changing epidemiology of Nepal and the shift of burden from communicable to non-communicable diseases (NCDs), it is important to revitalize their role with the changing times. The prevalence of ischemic stroke in Nepal is on the rise. However, very few people make i...
Source: Annals of Medicine - January 7, 2022 Category: Internal Medicine Authors: Babin Basnet Jayant Kumar Yadav Bikram Prasad Gajurel Yow Ka Shing Bipin Kandel Gaurav Nepal Source Type: research

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes syndrome: a case report from Nepal
Ann Med Surg (Lond). 2023 May 3;85(6):3026-3030. doi: 10.1097/MS9.0000000000000712. eCollection 2023 Jun.ABSTRACTMitochondrial encephalomyopathy, lactic acidosis, and stroke-like syndrome (MELAS) is a rare neurodegenerative inherited disorder that is characterized by stroke-like episodes, seizures, endocrine, and multiple system involvement. It is important to consider it as a differential diagnosis in a young patient with stroke-like episodes as it is progressive and has multiple complications.CASE PRESENTATION: A 28-year-old male presented with slurring of speech and drowsiness for 7 h. He was a diagnosed case of type 2 ...
Source: Annals of Medicine - June 26, 2023 Category: Internal Medicine Authors: Ram C Subedi Raju Paudel Sharma Paudel Lekhjung Thapa Subash Phuyal Naresh Kharbuja Ayush Adhikari Source Type: research

Atherosclerotic Cardiovascular Disease in South Asians in the United States: Epidemiology, Risk Factors, and Treatments: A Scientific Statement From the American Heart Association.
cial Populations Committee of the Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Quality of Care and Outcomes Research; and Stroke Council Abstract South Asians (from Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri Lanka) make up one quarter of the world's population and are one of the fastest-growing ethnic groups in the United States. Although native South Asians share genetic and cultural risk factors with South Asians abroad, South Asians in the United States can differ in socioeconomic status, education, healthcare behaviors, attitudes, and health in...
Source: Circulation - May 24, 2018 Category: Cardiology Authors: Volgman AS, Palaniappan LS, Aggarwal NT, Gupta M, Khandelwal A, Krishnan AV, Lichtman JH, Mehta LS, Patel HN, Shah KS, Shah SH, Watson KE, American Heart Association Council on Epidemiology and Prevention; Cardiovascular Disease and Stroke in Women and Sp Tags: Circulation Source Type: research

Status of prehospital delay and intravenous thrombolysis in the management of acute ischemic stroke in Nepal
The objective of this...
Source: BMC Neurology - July 9, 2019 Category: Neurology Authors: Gaurav Nepal, Jayant Kumar Yadav, Babin Basnet, Tirtha Man Shrestha, Ghanshyam Kharel and Rajeev Ojha Tags: Research article Source Type: research

Nepal: the pain of stroke treatment.
PMID: 32820059 [PubMed - as supplied by publisher]
Source: Practical Neurology - August 19, 2020 Category: Neurology Authors: Gajurel BP Tags: Pract Neurol Source Type: research