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Total 46 results found since Jan 2013.

Clinical and radiological risk factors for poststroke epilepsy in childhood
ConclusionSeizures, young age, cortical lesions, and multiple infarction at the time of stroke are independent risk factors for PSE in children following a first-ever AIS.
Source: Epilepsy and Behavior - October 5, 2018 Category: Neurology Source Type: research

Mortality outcomes in hospitals with public, private not-for-profit and private for-profit ownership in Chile 2001-2010
Discussion: The question about which type of hospital ownership performs better in Chile remains open. Policy decisions regarding health service provision requires more evidence explaining differences by ownership. Better controls for health risk and hospital characteristics are suggested to address these differences in hospital performance.
Source: Health Policy and Planning - March 10, 2015 Category: Health Management Authors: Cid Pedraza, C., Herrera, C. A., Prieto Toledo, L., Oyarzun, F. Tags: Original articles Source Type: research

The effect of physical activity on mortality and cardiovascular disease in 130  000 people from 17 high-income, middle-income, and low-income countries: the PURE study
We examined whether different amounts and types of physical activity are associated with lower mortality and CVD in countries at different economic levels. Methods In this prospective cohort study, we recruited participants from 17 countries (Canada, Sweden, United Arab Emirates, Argentina, Brazil, Chile, Poland, Turkey, Malaysia, South Africa, China, Colombia, Iran, Bangladesh, India, Pakistan, and Zimbabwe). Within each country, urban and rural areas in and around selected cities and towns were identified to reflect the geographical diversity. Within these communities, we invited individuals aged between 35 and 70 years ...
Source: The Lancet - September 22, 2017 Category: General Medicine Source Type: research

Canagliflozin Inhibits Human Endothelial Cell Proliferation and Tube Formation
In conclusion, the present study identified canagliflozin as a potent inhibitor of human EC proliferation. The anti-proliferative action of canagliflozin is observed in ECs isolated from both the venous and arterial circulation, and is partly due to the blockade of cyclin A expression. In addition, this study found that canagliflozin inhibits tube formation in cultured ECs and mouse aortic rings. Notably, these actions are specific for canagliflozin and not seen with other SGLT2 inhibitors. The ability of canagliflozin to exert these pleiotropic effects on EC function may contribute to both the adverse and salutary actions...
Source: Frontiers in Pharmacology - April 15, 2019 Category: Drugs & Pharmacology Source Type: research

Epidemiological profile of deaths after the 2010 earthquake in Chile - Lastra T J, Guzmán C G, Conejeros R C, Suárez V G, Chávez F O.
Background: On February 27, 2010 a powerful earthquake followed by a tsunami stroke Chile. The study of mortality during this emergency can provide important public health information. Aim: To describe the main characteristics of people who died during the...
Source: SafetyLit: All (Unduplicated) - February 21, 2013 Category: Global & Universal Tags: Age: Elder Adults Source Type: news

Usefulness and Pitfalls in Sodium Intake Estimation: Comparison of Dietary Assessment and Urinary Excretion in Chilean Children and Adults.
CONCLUSIONS: Our results showed that average sodium intake was higher than recommended in both children and adults (WHO ≤2,000mg/d). The sodium intake estimated by dietary assessment correlated with urinary excretion in all subjects, but in obese adults was more inaccurate than in children. Future studies to validate the appropriate test to assess sodium intake by age and nutritional status are warranted. PMID: 27279009 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - June 7, 2016 Category: Cardiology Authors: Campino C, Hill C, Baudrand R, Martínez-Aguayo A, Aglony M, Carrasco CA, Ferrada C, Loureiro C, Vecchiola A, Bancalari R, Grob F, Carvajal CA, Lagos CF, Valdivia C, Tapia-Castillo A, Fuentes CA, Mendoza C, Garcia H, Uauy R, Fardella CE Tags: Am J Hypertens Source Type: research

Hospital performance in a segmented and unequal health system: Chile 2001-2010.
Conclusions:: The analysis shows the inequities that exist between public hospitals and the private sector. PMID: 27991986 [PubMed - in process]
Source: Salud Publica de Mexico - August 31, 2016 Category: Epidemiology Authors: Cid C, Herrera CA, Prieto L Tags: Salud Publica Mex Source Type: research

Latin American Clinical Epidemiology Network Series – Paper 2: Apixaban was cost-effective vs. acenocoumarol in patients with nonvalvular atrial fibrillation with moderate to severe risk of embolism in Chile
The objective of this study was to assess the incremental cost –utility ratio (ICUR) for apixaban vs. acenocoumarol in patients treated in Chile's public health system.
Source: Journal of Clinical Epidemiology - October 15, 2016 Category: Epidemiology Authors: Fernando Lanas, Constanza Castro, Carlos Vallejos, Luis Bustos, Catherine de La Puente, Monica Velasquez, Carlos Zaror Tags: Series: the Latin American Clinical Epidemiology Network (LatinCLEN) Source Type: research

Atrial fibrillation in immigrant groups: a cohort study of all adults 45  years of age and older in Sweden
In conclusion, we observed substantial differences in incidence of AF between immigrant groups and the Swedish-born population. A greater awareness of the increased risk of AF development in some immigrant groups may enable for a timely diagnos is, treatment and prevention of its debilitating complications, such as stroke.
Source: European Journal of Epidemiology - July 12, 2017 Category: Epidemiology Source Type: research

Results of global fats and carbs study not very relevant for UK
Conclusion The results of the study have been presented in the media as if they overturn all current dietary guidelines. In the UK at least, that is completely misleading. The study results support the UK guidelines, having found that people who get around 50% of their calories from carbohydrates and 35% from fat, as recommended by Public Health England, were likely to live the longest. There are some limitations to the study, not least that observational studies cannot prove cause and effect. For example, the very low fat and high carbohydrate levels of diets found among some participants in the study might simply repres...
Source: NHS News Feed - August 30, 2017 Category: Consumer Health News Tags: Food/diet Source Type: news

Teaching NeuroImages: Typical neuroimaging features in high-altitude cerebral edema
A 61-year-old man presented with thunderclap headache followed by loss of consciousness, 2 days after arriving in Atacama Desert, Andes Mountains, Chile, at 4,000 meters. Examination showed coma. Mechanical ventilation was necessary. He had progressive improvement after transfer to low altitudes. Brain MRI showed diffuse vasogenic edema and microhemorrhages (figure), and high-altitude cerebral edema (HACE) was diagnosed.
Source: Neurology - October 2, 2017 Category: Neurology Authors: Marussi, V. H. R., Pedroso, J. L., Piccolo, A. M., Barsottini, O. G., Moraes, F. M. d., Oliveira, A. S. B., Freitas, L. F., Amaral, L. L. F. d. Tags: MRI, Other cerebrovascular disease/ Stroke, All Clinical Neurology RESIDENT AND FELLOW SECTION Source Type: research

7 medtech stories we missed this week: Oct. 20, 2017
[Image from unsplash.com]From InspireMD’s distribution deal to RenalGuard touting a new study, here are seven medtech stories we missed this week but thought were still worth a mention. 1. InspireMD inks Chile distribution deal InspireMD announced in an Oct. 12 press release that it has signed a distribution deal with CorpMedical Chile to distribute the MGuard Prime Embolic Protection System (EPS). The MGuard Prime EPS treats acute coronary syndromes like acute myocardial infarctions. 2. Medacta launches MiniMed hip stem Medacta has launched its MiniMAX Hip System in the U.S., according to an Oct. 12 press release. ...
Source: Mass Device - October 20, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: 510(k) Cardiovascular Clinical Trials Diagnostics Food & Drug Administration (FDA) Implants Orthopedics Patient Monitoring Regulatory/Compliance Surgical Ultrasound Esaote Hill-Rom Holdings Inc. Honeywell InspireMD Medacta Source Type: news

Spanish version of the mini-BESTest: a translation, transcultural adaptation and validation study in patients with Parkinson’s disease
Balance is affected in numerous neurologic disorders, like stroke, multiple sclerosis and Parkinson’s disease contributing to falls, and diminishing quality of life and functionality. The mini-BESTest is one of the most recommended scales to detect balance disorders in people with Parkinson’s disease, which has solid psychometric properties. Unfortunately, this scale has not been validated in Chile and there are no other validated scales that can determine balance disorders in patients with Parkinson’s disease to date. The study objective was to validate the mini-BESTest scale in Chilean Parkinson’s disease patient...
Source: International Journal of Rehabilitation Research - May 12, 2020 Category: Rehabilitation Tags: Original Articles Source Type: research

Incidence, risk factors, prognosis, and health-related quality of life after stroke in a low-resource community in Chile (ÑANDU): a prospective population-based study
Publication date: Available online 7 January 2021Source: The Lancet Global HealthAuthor(s): Pablo M Lavados, Lorena Hoffmeister, Ana M Moraga, Angelica Vejar, Carolina Vidal, Constanza Gajardo, Bernardita Portales, Daniela San Martín, Eduardo Lopez, Alexis Rojo, Veronica V Olavarria, Juan Almeida, Alejandro M Brunser, Paula Muñoz Venturelli, Violeta Diaz, Arnold Hoppe, Claudio Sacks
Source: The Lancet Global Health - January 8, 2021 Category: International Medicine & Public Health Source Type: research

Breaking Down Barriers: Easter Island's First Telestroke Thrombolysis Experience and Case Report
Easter Island (Rapa Nui), Chile, is remote, located in the Polynesian Triangle in Oceania. The closest continental point is Chile, 3,512  km east. It has a population of 7,750 inhabitants, who are Chilean citizens, and receives more than 60,000 tourists a year. For this entire population, there is a medium complexity hospital without a neurology specialist. In 2019, local professionals were trained in a Telestroke program with remot e clinical support conducted by neurologists located on mainland Chile.
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2022 Category: Neurology Authors: E. Mazzon, C. Delfino, S. Mirelis, M. Ar évalo, D. Rojas, L. Lara, D. Carcamo, F. Jurado, D. Rocha, P. Muñoz Venturelli, E. Mansilla Tags: Case Report Source Type: research