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Condition: Stroke
Cancer: Childhood Cancer

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Total 243 results found since Jan 2013.

Risk of Radiation Vasculopathy and Stroke in Pediatric Patients Treated with Proton Therapy for Brain and Skull Base Tumors
Childhood cancer survivors are at risk of vasculopathy. This review of 651 children treated with proton therapy estimates the rate of serious vasculopathy is 2.6% at 3 years following treatment. Young age and doses ≥54 CGE to the suprasellar region are the dominant risk factors.
Source: International Journal of Radiation Oncology * Biology * Physics - March 29, 2018 Category: Radiology Authors: Matt D. Hall, Julie A. Bradley, Ronny L. Rotondo, Ricardo Hanel, Chetan Shah, Christopher G. Morris, Philipp R. Aldana, Daniel J. Indelicato Tags: Clinical Investigation Source Type: research

New 'unified theory' of childhood leukemia raises possibility of preventing the disease
Kids who develop acute lymphoblastic leukemia may be the victims of a triple-whammy stroke of bad luck, according to a provocative new theory from a respected British cancer researcher.If the explanation turns out to be correct, it would be good news for the most common type of childhood cancer:...
Source: Los Angeles Times - Science - May 23, 2018 Category: Science Authors: Melissa Healy Source Type: news

The management of childhood cancer survivors at risk for stroke: A Delphi survey of regional experts
Pediatric Blood&Cancer, EarlyView.
Source: Pediatric Blood and Cancer - August 10, 2018 Category: Cancer & Oncology Authors: Lisa B.Kenney , BethanyAmes , Alexis L.Michaud , David N.Williams , Peter E.Manley , Nicole J.Ullrich Source Type: research

Mayo Clinic Radio: Childhood cancer awareness / Ken Burns / Does aspirin prevent heart attack and stroke?
There are four words no parent or family ever wants to hear: Your child has cancer.?Families facing pediatric cancer experience a wide range of emotions, often feeling scared, overwhelmed, frustrated, helpless or hopeless.?And each family member may experience different emotions at different times, making it difficult to navigate and support each other. These and related [...]
Source: News from Mayo Clinic - September 10, 2018 Category: Databases & Libraries Source Type: news

Zero Hunger: our actions today are our future tomorrow
This article is part of a series of opinion pieces to mark World Food Day October 16   José Graziano da Silva is Director-General of the Food and Agriculture Organization of the United NationsThe post Zero Hunger: our actions today are our future tomorrow appeared first on Inter Press Service.
Source: IPS Inter Press Service - Health - October 15, 2018 Category: International Medicine & Public Health Authors: Jose Graziano da Silva Tags: Development & Aid Economy & Trade Editors' Choice Featured Food & Agriculture Global Headlines Health Poverty & SDGs TerraViva United Nations World Food Day 2018 Source Type: news

Air Pollution and Non-Communicable Diseases: A review by the Forum of International Respiratory Societies' Environmental Committee. Part 2: Air pollution and organ systems.
Abstract Although air pollution is well-known to be harmful to the lung and airways, it can also damage most other organ systems of the body. It is estimated that about 500,000 lung cancer deaths and 1.6 million chronic obstructive pulmonary disease (COPD) deaths can be attributed to air pollution, but air pollution may also account for 19% of all cardiovascular deaths and 21% of all stroke deaths. Air pollution has been linked to other malignancies, such as bladder cancer and childhood leukemia. Lung development in childhood is stymied with exposure to air pollutants, and poor lung development in children predict...
Source: Chest - November 9, 2018 Category: Respiratory Medicine Authors: Schraufnagel DE, Balmes J, Cowl CT, De Matteis S, Jung SH, Mortimer K, Perez-Padilla R, Rice MB, Riojas-Rodroguez H, Sood A, Thurston GD, To T, Vanker A, Wuebbles DJ Tags: Chest Source Type: research

IJERPH, Vol. 16, Pages 548: What Do We Know about Diet and Markers of Cardiovascular Health in Children: A Review
dmore Chronic diseases such as cancer, diabetes, and cardiovascular diseases (CVD) are the main health concerns in the 21st century, with CVD as the number one cause of mortality worldwide. Although CVD hard endpoints such as stroke or heart attack do not usually occur in children, evidence shows that the manifestation of CVD risk factors begins in childhood, preceding clinical complications of CVD in adulthood. Dietary intake is a modifiable risk factor that has been shown to make a substantial contribution to the risk of CVD in adulthood. However, less is known about the association between dietary intake and markers...
Source: International Journal of Environmental Research and Public Health - February 14, 2019 Category: Environmental Health Authors: Pouya Saeedi Amin Shavandi Paula M.L. Skidmore Tags: Review Source Type: research

Cardiovascular disease after childhood acute lymphoblastic leukaemia: a cohort study.
CONCLUSIONS: Despite attempts to reduce cardiotoxicity in childhood cancer treatment, CVD risks in ALL survivors treated more recently do not seem to have declined. PMID: 30852834 [PubMed - in process]
Source: Swiss Medical Weekly - February 24, 2019 Category: General Medicine Authors: Hau EM, Caccia JN, Kasteler R, Spycher B, Suter T, Ammann RA, von der Weid NX, Kuehni CE Tags: Swiss Med Wkly Source Type: research

Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier
We examined a possible protective effect of OX-A against LPS-induced ROS formation and microglia activation. To mimic in vitro the connection between gut and brain and to study the putative effect on the cortical microglia, we used a co-culture of Caco-2 cells and primary cortical microglia with Caco-2 cells placed at the apical side of a transwell and primary cortical microglia at the basolateral side. All treatments used to study the apical vs. basal connection were applied to the apical compartment. We used DHR (10 μM, 20 min), a cell-permeable fluorogenic probe useful for the detection of ROS formation, to dete...
Source: Frontiers in Endocrinology - April 9, 2019 Category: Endocrinology Source Type: research

Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

Hypothalamic-Pituitary Disorders in Childhood Cancer Survivors: Prevalence, Risk Factors and Long-Term Health Outcomes.
CONCLUSIONS: HP radiotherapy, CNS injury and, to a lesser extent, chemotherapy are associated with HP disorders, which are associated with adverse health outcomes. PMID: 31373627 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - August 1, 2019 Category: Endocrinology Authors: van Iersel L, Li Z, Srivastava DK, Brinkman TM, Bjornard KL, Wilson CL, Green DM, Merchant TE, Pui CH, Howell RM, Smith SA, Armstrong GT, Hudson MM, Robison LL, Ness KK, Gajjar A, Krull KR, Sklar CA, van Santen HM, Chemaitilly W Tags: J Clin Endocrinol Metab Source Type: research

Vital Signs: Estimated Proportion of Adult Health Problems Attributable to Adverse Childhood Experiences and Implications for Prevention - 25 States, 2015-2017.
CONCLUSIONS AND IMPLICATIONS FOR PUBLIC HEALTH PRACTICE: Efforts that prevent adverse childhood experiences could also potentially prevent adult chronic conditions, depression, health risk behaviors, and negative socioeconomic outcomes. States can use comprehensive public health approaches derived from the best available evidence to prevent childhood adversity before it begins. By creating the conditions for healthy communities and focusing on primary prevention, it is possible to reduce risk for adverse childhood experiences while also mitigating consequences for those already affected by these experiences. PMID: 316...
Source: MMWR Morb Mortal Wkl... - November 7, 2019 Category: Epidemiology Authors: Merrick MT, Ford DC, Ports KA, Guinn AS, Chen J, Klevens J, Metzler M, Jones CM, Simon TR, Daniel VM, Ottley P, Mercy JA Tags: MMWR Morb Mortal Wkly Rep Source Type: research

How to Keep Alzheimer ’s From Bringing About the Zombie Apocalypse
I tried to kill my father for years. To be fair, I was following his wishes. He’d made it clear that when he no longer recognized me, when he could no longer talk, when the nurses started treating him like a toddler, he didn’t want to live any longer. My father was 58 years old when he was diagnosed with Alzheimer’s disease. He took the diagnosis with the self-deprecating humor he’d spent a lifetime cultivating, constantly cracking jokes about how he would one day turn into a zombie, a walking corpse. We had a good 10 years with him after the diagnosis. Eventually, his jokes came true. Seven years ...
Source: TIME: Health - November 20, 2019 Category: Consumer Health News Authors: Jay Newton-Small Tags: Uncategorized Alzheimer's Disease Source Type: news