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Total 356 results found since Jan 2013.

5 ways to handle chronic pain
Chronic pain conditions now affect more than 116 million Americans, according to the Institute of Medicine, a figure that dwarfs the number of people who suffer from diabetes, coronary heart disease/stroke and cancer combined.
Source: WDSU.com - Health - May 23, 2013 Category: Consumer Health News Source Type: news

Deal with your chronic pain
Chronic pain conditions now affect more than 116 million Americans, according to the Institute of Medicine, a figure that dwarfs the number of people who suffer from diabetes, coronary heart disease/stroke and cancer combined.
Source: CNN.com - Health - May 23, 2013 Category: Consumer Health News Source Type: news

157 E-Books New to JEFFLINE
Scott Library added these 157 e-books to the growing collection in May and June: Accurate Results in the Clinical Laboratory Adult Emergency Medicine Adult-Gerontology and Family Nurse Practitioner Certification Examination (4th ed.) Advanced Assessment: Interpreting Findings and Formulating Differential Diagnoses (2nd ed.) Advancing Your Career: Concepts of Professional Nursing (5th ed.) Arrhythmia Essentials Atlas of Advanced Operative Surgery Atlas of Clinical Neurology (3rd ed.) Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches Atlas of Human Infectious Diseases Atlas of No...
Source: What's New on JEFFLINE - June 25, 2013 Category: Databases & Libraries Authors: Gary Kaplan Tags: All News Clinicians Researchers Students Teaching Faculty Source Type: news

Drugs to be offered to women at high risk of breast cancer
The National Institute of Health and Care Excellence (NICE) has today released updated guidelines on the care of women who are at increased risk of breast cancer due to their family history. One of the main changes to the original guidance from 2004 is that NICE now recommends drug treatment with tamoxifen or raloxifene to reduce risk of breast cancer in a specific group of women who are at high risk of breast cancer and have not had the disease. They say that these treatments could help prevent breast cancer in about 488,000 women aged 35 years and older. The updated guideline has also made changes to the recommende...
Source: NHS News Feed - June 25, 2013 Category: Consumer Health News Tags: Cancer Medical practice QA articles Source Type: news

If you could propose one idea to help improve health care delivery in the United States, what would it be?
Thumbnail: Tags: conversationsphrma conversationslarry hausnermyrl weinbergchris hansennancy brownContributors: 11621161115911631173Contributions: Read Larry Hausner's bio Despite the rapid development of innovative technologies in the health care field, we have yet to discover a panacea that will easily transform our health care system into one that provides high-quality and cost-effective care.  What we have discovered and come to agree on over the last decade is that our sick care system must be reconfigured to a health care system that emphasizes wellness and prevention.  For that reason, I offer ...
Source: PHRMA - June 24, 2013 Category: Pharmaceuticals Authors: rlowe Source Type: news

Why acupuncture is giving sceptics the needle
Acupuncture has been prescribed by half of Britain's doctors, but after 3,000 clinical trials its efficacy remains unproven. So is the NHS making a grave error in supporting this ancient treatment?• Are vitamin pills a sham? Q&A with Dr. Paul OffitYou can't get crystal healing on the NHS. The Department of Health doesn't fund faith healing. And most doctors believe magnets are best stuck on fridges, not patients. But ask for a treatment in which an expert examines your tongue, smells your skin and tries to unblock the flow of life force running through your body with needles and the NHS will be happy to oblige.The govern...
Source: Guardian Unlimited Science - July 26, 2013 Category: Science Authors: David Derbyshire Tags: Culture Health Science and scepticism Features NHS Alternative medicine The Observer Source Type: news

Preparation of well-defined ibuprofen prodrug micelles by RAFT polymerization.
Abstract Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat acute pain, fever and inflammation and are being explored in a new indication in cancer. Side effects associated with long-term use of NSAIDs such as gastrointestinal damage and elevated risk of stroke, however, can limit their use and exploration in new indications. Here we report a facile method to prepare well-defined amphiphilic diblock copolymer NSAID prodrugs by direct reversible addition fragmentation transfer (RAFT) polymerization of the acrylamide derivative of ibuprofen (IBU), a widely used NSAID. The synthesis and self-as...
Source: Biomacromolecules - August 12, 2013 Category: Biochemistry Authors: Hasegawa U, van der Vlies AJ, Wandrey C, Hubbell JA Tags: Biomacromolecules Source Type: research

Effect of Comorbidities and Psychosocial Conditions on HRQOL After Lumbar Spinal Fusion
To investigate the association between comorbidities and its impact on HRQOL scores following spinal fusion surgery. The SF-36, ODI and rating scales (0 to 10) for back and leg pain were administered prospectively to patients who had lumbar spine fusion. Data on 12 medical (diabetes, heart disease, DVT/PVD, hypertension, cancer, kidney disease, asthma, autoimmune diseases, osteoarthritis, osteoporosis, and stroke) and 5 psychosocial conditions (depression, anxiety, obesity, smoking status, and worker's compensation status) were collected. A Generalized Linear Model was created to test the impact of these comorbidities on ...
Source: Annals of Epidemiology - August 20, 2013 Category: Epidemiology Authors: N. Das, S.D. Glassman, M. Djurasovic, K.R. Bratcher, J.B. Nienhuis, L.Y. Carreon Tags: Abstracts Source Type: research

A rare cause of headache-the importance of a tissue diagnosis and perseverance
A 64 year old diabetic hypertensive milkman presented in September 2011 with 4 months progressive constant right frontotemporal retro–orbital pain. It was worse at night affecting sleep with slight right field blurring and later vomiting. Full examination including blood pressure was normal with acuities 6/9. Tension type headache was considered. Initial brain CT was reported as normal. With concern about giant cell arteritis steroids were trialled although ESR was 8 and CRP 25 with no other clinical features: pain reduction was short–lived and temporal artery biopsy negative. Symptoms worsened despite analgesi...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Defty, H., Cavazza, A., Warner, G. Tags: Immunology (including allergy), Cranial nerves, Headache (including migraine), Neurooncology, Pain (neurology), Stroke, Hypertension, CNS cancer, Ophthalmology, Pain (palliative care), Anxiety disorders (including OCD and PTSD), Radiology, Disability, Dru Source Type: research

Music gives people a voice when words fail them at the end of their lives | Bob Heath
A music therapist describes how improvising songs can open a vital channel of communication in palliative careAll that was dear to me, down below the seaI cannot hold this piece of driftwoodWhen life abandons meLiz, a patient at the Sobell House hospice, 2013In palliative care, when clients and their therapists get to know one another they do so with a shared knowledge, whether voiced or not, that while both of them are going to die eventually, at least one of them is going to be doing it very soon.The relationship between client and therapist is always unique. And whatever you may think about "therapy", all (or most) of i...
Source: Guardian Unlimited Science - November 5, 2013 Category: Science Tags: Psychology theguardian.com Music Health Medical research & wellbeing Society Life and style Editorial Science Source Type: news

Was Arafat poisoned by radioactive polonium?
Yasser Arafat The Maybe-Murder of Yasser Arafat: In a must-read post on Wired Science Blogs, Deborah Blum points out that despite the recent confirmation of traces of radioactive polonium-210 in the exhumed remains of Palestinian Liberation Organization chairman Yasser Arafat, it is far from certain that he died of radiation poisoning. In October 2004, a month before he died, Arafat developed vomiting and abdominal pain. The symptoms were so severe that he was transferred from his home on the West Bank to a hospital in France. The direct cause of Arafat’s death — which occurred on November 11 — was a hemorrha...
Source: The Poison Review - November 12, 2013 Category: Toxicology Authors: Leon Tags: Medical acute radiation syndrome arafat cesium himalayan mountain salt hypokalemia pablo neruda poisoning polonium-210 radioactivity smacc 2013 weekly web review in toxicology Source Type: news

Isolated Shoulder Palsy due to Cortical Infarction: A Case Report and Literature Review of Clinicoradiological Correlations
We report an 80-year-old woman with isolated shoulder palsy because of cortical ischemic infarction in the base of the left precentral gyrus as confirmed by brain magnetic resonance imaging. In our patient, cardiogenic embolism or Trousseau syndrome associated with lung cancer was considered the cause of ischemic infarction. Physicians should consider small cortical infarction, when a patient complains of sudden onset of shoulder weakness without pain. In line with the previous reports, a responsible cortical lesion in our patient corresponded to motor shoulder area in the motor homunculus reported to be located more media...
Source: Journal of Stroke and Cerebrovascular Diseases - September 4, 2013 Category: Neurology Authors: Akiko Kawasaki, Keisuke Suzuki, Hidehiro Takekawa, Norito Kokubun, Masanari Yamamoto, Yohei Asakawa, Madoka Okamura, Koichi Hirata Tags: Case Reports Source Type: research

Lamotrigine for chronic neuropathic pain and fibromyalgia in adults.
CONCLUSIONS: Large, high-quality, long-duration studies reporting clinically useful levels of pain relief for individual participants provided no convincing evidence that lamotrigine is effective in treating neuropathic pain and fibromyalgia at doses of about 200 to 400 mg daily. Given the availability of more effective treatments including antiepileptics and antidepressant medicines, lamotrigine does not have a significant place in therapy based on the available evidence. The adverse effect profile of lamotrigine is also of concern. PMID: 24297457 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - December 3, 2013 Category: Journals (General) Authors: Wiffen PJ, Derry S, Moore RA Tags: Cochrane Database Syst Rev Source Type: research

Getting Married and Not Getting Healthy: Decades of Data
If you get married, will you get healthier? Here I scrutinize decades of data, and take on the claims about physical health (including weight, exercise, blood pressure, stroke, heart health, sleep, Alzheimer’s, epilepsy, and cancer), and mental health (including emotional health, depression, suicide, and psychopathy). read more
Source: Psychology Today Food and Diet Center - December 28, 2013 Category: Nutrition Authors: Bella DePaulo, Ph.D. Tags: Depression Diet Health Relationships Alzheimer’s blood pressure cancer chronic illness emotional health epilepsy exercise heart disease mental health methodological flaws myths about single people pain physical health p Source Type: news

Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities
A family of detoxifying enzymes called aldehyde dehydrogenases (ALDHs) has been a subject of recent interest, as its role in detoxifying aldehydes that accumulate through metabolism and to which we are exposed from the environment has been elucidated. Although the human genome has 19 ALDH genes, one ALDH emerges as a particularly important enzyme in a variety of human pathologies. This ALDH, ALDH2, is located in the mitochondrial matrix with much known about its role in ethanol metabolism. Less known is a new body of research to be discussed in this review, suggesting that ALDH2 dysfunction may contribute to a variety of h...
Source: Physiological Reviews - January 1, 2014 Category: Physiology Authors: Chen, C.-H., Ferreira, J. C. B., Gross, E. R., Mochly-Rosen, D. Tags: Articles Source Type: research