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Condition: Hypertension
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Total 489 results found since Jan 2013.

Rates and Determinants of 5-Year Outcomes After Atrial Fibrillation-Related Stroke: A Population Study Clinical Sciences
Conclusions— AF-stroke is associated with considerable long-term morbidity, fatality, stroke recurrence, and nursing home requirement. Adequately resourced national AF strategies to improve AF detection and prevention are needed.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Hayden, D. T., Hannon, N., Callaly, E., Ni Chroinin, D., Horgan, G., Kyne, L., Duggan, J., Dolan, E., O'Rourke, K., Williams, D., Murphy, S., Kelly, P. J. Tags: Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Diabetes and stroke prevention: a review.
Authors: Hewitt J, Castilla Guerra L, Fernández-Moreno Mdel C, Sierra C Abstract Stroke and diabetes mellitus are two separate conditions which share multiple common threads. Both are increasing in prevalence, both are diseases which affect blood vessels, and both are associated with other vascular risk factors, such as hypertension and dyslipidemia. Abnormal glucose regulation, of which diabetes is one manifestation, is seen in up to two-thirds of people suffering from an acute stroke. Surprisingly, aggressive management of glucose after an acute stroke has not been shown to improve outcome or reduce the incidenc...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Risk Factors, Stroke Prevention Treatments, and Prevalence of Cerebral Microbleeds in the Framingham Heart Study Brief Reports
Conclusions— We observed the expected association of hypertension with deep CMB and low cholesterol and APOE 4 with lobar CMB. In addition, statin use was independently associated with CMB risk. This potential adverse effect of statin use needs to be examined in other cohorts.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Romero, J. R., Preis, S. R., Beiser, A., DeCarli, C., Viswanathan, A., Martinez-Ramirez, S., Kase, C. S., Wolf, P. A., Seshadri, S. Tags: Risk Factors for Stroke, Epidemiology Brief Reports Source Type: research

Stroke in Patients With Aortic Stenosis: The Simvastatin and Ezetimibe in Aortic Stenosis Study Clinical Sciences
Conclusions— In patients with aortic stenosis not prescribed oral anticoagulation, atrial fibrillation, AVR with concomitant coronary artery bypass grafting, and CHA2DS2-VASc score were the major predictors of stroke. Incident stroke was strongly associated with mortality. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00092677.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Greve, A. M., Dalsgaard, M., Bang, C. N., Egstrup, K., Ray, S., Boman, K., Rossebo, A. B., Gohlke-Baerwolf, C., Devereux, R. B., Kober, L., Wachtell, K. Tags: Thrombosis risk factors, CV surgery: valvular disease, Acute Cerebral Infarction Clinical Sciences Source Type: research

Metformin-inclusive Therapy Reduces the Risk of Stroke in Patients with Diabetes: A 4-Year Follow-up Study
Metformin is a kind of oral hypoglycemic agents commonly prescribed to patients with diabetes mellitus. Although past studies had proven its protective effect on cardiovascular risk and related mortality, the evidence of metformin on stroke prevention was still insufficient and conflicting. Our study randomly selected 14,856 patients with diabetes from the database provided by the Taiwan National Health Research Institute, and 2 cohorts were formulated according to whether metformin was in the prescription record. All cases were followed up for 4 years to track their stroke incidence. As a result, 701 (17.5%) of 3999 diabe...
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2013 Category: Neurology Authors: Yuan-Yang Cheng, Hsin-Bang Leu, Tzeng-Ji Chen, Chen-Ling Chen, Chia-Hua Kuo, Shin-Da Lee, Chung-Lan Kao Tags: Original Articles Source Type: research

Differences in lipid profiles in two Hispanic ischemic stroke populations
ConclusionWe found significant differences in lipid fractions in Hispanic ischemic stroke patients, with lower total cholesterol and low‐density lipoprotein, and higher triglyceride levels in Mexicans. These findings highlight the heterogeneity of dyslipidemia among the Hispanic race‐ethnic group and may lead to different secondary prevention strategies.
Source: International Journal of Stroke - December 20, 2013 Category: Neurology Authors: A. Arauz, J. G. Romano, A. Ruiz‐Franco, T. Shang, C. Dong, T. Rundek, S. Koch, B. Hernández‐Curiel, J. Pacheco, P. Rojas, F. Ruiz‐Navarro, M. Katsnelson, R. L. Sacco Tags: Research Source Type: research

Occurrence and Predictors of Persistent Impaired Glucose Tolerance After Acute Ischemic Stroke or Transient Ischemic Attack
Conclusions: Half of the patients with impaired glucose tolerance after a TIA or ischemic stroke have persistent impaired glucose tolerance. We provide a prediction model to identify patients at risk of persistent impaired glucose tolerance, with statin use, triglyceride, and fasting plasma glucose as the most important predictors, which after external validation might be used to optimize secondary prevention.
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2014 Category: Neurology Authors: Susanne Fonville, Heleen M. den Hertog, Adrienne A.M. Zandbergen, Peter J. Koudstaal, Hester F. Lingsma Tags: Original Articles Source Type: research

Meta-analysis of folic acid efficacy trials in stroke prevention: Insight into effect modifiers
Conclusions: Folic acid supplementation could reduce the stroke risk in regions without folic acid fortification, particularly in trials using a relatively low dosage of folic acid and with low vitamin B12 levels.
Source: Neurology - May 8, 2017 Category: Neurology Authors: Zhao, M., Wu, G., Li, Y., Wang, X., Hou, F. F., Xu, X., Qin, X., Cai, Y. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Clinical trials Randomized controlled (CONSORT agreement), All epidemiology ARTICLE Source Type: research

Overenthusiastic stroke risk factor modification in the over-80s: Are we being disingenuous to ourselves, and to our oldest patients?
Statins and antihypertensive therapy are widely used in our oldest patients (ie, those aged over 80 years). The epidemiology suggests that, by this age, hypertension is not an attributable risk factor for stroke, and hypercholesterolaemia has little effect on stroke risk overall. The largest trials of antihypertensive therapy and statins in this age group show at best a marginal clinical reduction in stroke and very modest clinical reductions in other cardiovascular end points. Older patients have very diverse views on the relative importance of stroke and death as end points, and these differ from physicians’ views....
Source: Evidence-Based Medicine - July 18, 2014 Category: Internal Medicine Authors: Byatt, K. Tags: Geriatric medicine, Clinical trials (epidemiology), Editor's choice, Press releases, Drugs: cardiovascular system, Stroke, Hypertension, Ethics, Legal and forensic medicine, Lipid disorders Perspective Source Type: research

Desirable Low-Density Lipoprotein Cholesterol Levels for Preventing Stroke Recurrence Clinical Sciences
Conclusions—The composite risk of stroke and transient ischemic attack reduced in the postrandomized LDL cholesterol level of 80 to 100 mg/dL after adjusting for statin usage.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00221104.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Naohisa Hosomi, Kazuo Kitagawa, Yoji Nagai, Yoko Nakagawa, Shiro Aoki, Tomohisa Nezu, Tatsuo Kagimura, Hirofumi Maruyama, Hideki Origasa, Kazuo Minematsu, Shinichiro Uchiyama, Masayasu Matsumoto Tags: Lipids and Cholesterol, Secondary Prevention, Treatment Original Contributions Source Type: research

Stroke Down to Fifth-Leading Killer in U.S. -- Here's What the Statistical Change Really Means
In the 1970s, Joseph Broderick was a resident at the Mayo Clinic in need of a focus for his fellowship. He decided to give stroke research a try. Part of the lure was all the unanswered questions, like: Who is most likely to have a stroke? Why do they have it when others seemingly like them don't? Is stroke getting more or less common? What can be done to prevent it? Another part of the lure was a landmark study on the frequency of stroke being done in the hospital's hometown of Rochester, Minnesota. Being part of it meant working for one of the nation's leading stroke researchers at the time, Jack Whisnant. By the mid-...
Source: Healthy Living - The Huffington Post - January 12, 2015 Category: Consumer Health News Source Type: news

How People With Diabetes Can Lower Stroke Risk
After spending nearly two decades trying to manage her Type 2 diabetes, Agnes Czuchlewski landed in the emergency room in 2015, with news that she’d just experienced a heart attack. She also learned that she had metabolic syndrome, a cluster of conditions that includes diabetes but also brings higher risk of heart disease and stroke. “Because I needed to lose quite a bit of weight when I was first diagnosed, I was focused on the number I saw on the scale, and then on my blood-sugar numbers,” recalls Czuchlewski, 68, who lives in New York City. “I didn’t realize other numbers came into play, li...
Source: TIME: Health - November 10, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Disease healthscienceclimate Source Type: news

The effect of statins on National Institutes of Health Stroke Scale (NiHSS) in Ischemic stroke.
Conclusion. According to the findings of this research, taking statins before the onset of stroke and immediately after it showed no significant difference in the level of following dysfunction, measured with NIHSS, and further studies are necessary. PMID: 28316706 [PubMed]
Source: Journal of Medicine and Life - March 23, 2017 Category: Journals (General) Tags: J Med Life Source Type: research

The Riga East University Hospital Stroke Registry-An Analysis of 4915 Consecutive Patients with Acute Stroke
Conclusions: Our stroke registry data are comparable to those of other major registries. Analysis of stroke registry data is important for improving stroke care and obtaining additional information for stroke studies.PMID:34207100 | DOI:10.3390/medicina57060632
Source: Medicina (Kaunas) - July 2, 2021 Category: Universities & Medical Training Authors: Guntis Karelis Madara Micule Evija Klavina Iveta Haritoncenko Ilga Kikule Biruta Tilgale Inese Polaka Source Type: research