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Condition: Diabetes
Procedure: Percutaneous Coronary Intervention

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Total 463 results found since Jan 2013.

Effectiveness of Percutaneous Coronary Intervention With Drug-Eluting Stents Compared With Bypass Surgery in Diabetics With Multivessel Coronary Disease: Comprehensive Systematic Review and Meta-analysis of Randomized Clinical Data Coronary Heart Disease
Conclusions These data demonstrate that CABG in diabetic patients with MVD at low to intermediate surgical risk (defined as EUROSCORE <5) is superior to MVD PCI with DES. CABG decreased overall death, nonfatal myocardial infarction, and repeat revascularization at the expense of an increase in stroke risk.
Source: JAHA:Journal of the American Heart Association - August 7, 2013 Category: Cardiology Authors: Hakeem, A., Garg, N., Bhatti, S., Rajpurohit, N., Ahmed, Z., Uretsky, B. F. Tags: Coronary Heart Disease Source Type: research

Cost‐effectiveness of percutaneous coronary intervention with drug‐eluting stents in patients with multivessel coronary artery disease compared to coronary artery bypass surgery 5 years after intervention
Conclusions. Cost‐effectiveness analysis of DES‐PCI vs. CABG demonstrated that CABG is the most effective, but most costly, treatment for preventing MACCE in patients with multivessel disease. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - January 9, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Lisa Krenn, Christoph Kopp, Dietmar Glogar, Irene M Lang, Georg Delle‐Karth, Thomas Neunteufl, Gerhard Kreiner, Alexandra Kaider, Jutta Bergler‐Klein, Aliasghar Khorsand, Maryam Nikfardjam, Günther Laufer, Gerald Maurer, Mariann Gyöngyösi Tags: Research Article Source Type: research

Outcome of primary PCI - An Indian tertiary care center experience.
CONCLUSION: Our study has shown that PPCI is feasible with good outcomes in Indian scenario. Even though the recommended door-to-balloon time can be achieved, the total ischemic time remained long. CS in the setting of STEMI was associated with poor outcomes. PMID: 24581092 [PubMed - in process]
Source: Indian Heart J - January 1, 2014 Category: Cardiology Authors: Subban V, Lakshmanan A, Victor SM, Pakshirajan B, Udayakumaran K, Gnanaraj A, Solirajaram R, Krishnamoorthy J, Janakiraman E, Pandurangi UM, Kalidoss L, Mullasari AS Tags: Indian Heart J Source Type: research

Abstract 249: Economic Outcomes for Patients with Acute Coronary Syndrome Managed with Percutaneous Coronary Intervention and Receiving Prasugrel or Ticagrelor: A Retrospective US Hospital Database Analysis Session Title: Poster Session II
Conclusion: Economic outcomes of ACS-PCI pts receiving pras were similar to ticag for the primary population with significant savings in total and medical costs for pts without prior TIA or stroke. These data indicate that ticag has no economic advantage compared with pras in routine clinical practice.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Molife, C., Frech-Tamas, F., Effron, M. B., DeKoven, M., Karkare, S., Zhu, Y. E., Larmore, C., Lu, J., Lee, W. C., Mc Collam, P., Marrett, E., Vetrovec, G. W. Tags: Session Title: Poster Session II Source Type: research

Outcomes With Coronary Artery Bypass Graft Surgery Versus Percutaneous Coronary Intervention for Patients With Diabetes Mellitus: Can Newer Generation Drug-Eluting Stents Bridge the Gap? Coronary Interventions
Conclusions— In patients with diabetes mellitus, evidence from indirect comparison shows similar mortality between CABG and PCI using cobalt–chromium everolimus-eluting stent. CABG was associated with numerically excess stroke and PCI with cobalt–chromium everolimus-eluting stent with numerically increased repeat revascularization. This hypothesis needs to be tested in future trials.
Source: Circulation: Cardiovascular Interventions - August 19, 2014 Category: Cardiology Authors: Bangalore, S., Toklu, B., Feit, F. Tags: Catheter-based coronary interventions: stents, CV surgery: coronary artery disease, Chronic ischemic heart disease Source Type: research

Coronary artery bypass grafting vs. percutaneous coronary intervention for patients with three-vessel disease: final five-year follow-up of the SYNTAX trial
Conclusion Five-year results of patients with 3VD treated with CABG or PCI using the first-generation paclitaxel-eluting DES suggest that CABG should remain the standard of care as it resulted in significantly lower rates of death, MI, and repeat revascularization, while stroke rates were similar. For patients with low SYNTAX scores, PCI is an acceptable revascularization strategy, although at a price of significantly higher rates of repeat revascularization. Clinical trial registration NCT00114972.
Source: European Heart Journal - October 21, 2014 Category: Cardiology Authors: Head, S. J., Davierwala, P. M., Serruys, P. W., Redwood, S. R., Colombo, A., Mack, M. J., Morice, M.-C., Holmes, D. R., Feldman, T. E., Stahle, E., Underwood, P., Dawkins, K. D., Kappetein, A. P., Mohr, F. W. Tags: Coronary artery disease Source Type: research

Meta-analysis of three randomized controlled trials comparing coronary artery bypass grafting with percutaneous coronary intervention using drug-eluting stenting in patients with diabetes
CONCLUSIONS In patients with diabetes, PCI was associated with no difference in death and MI at 1 year. However, at 5 years, PCI was associated with a higher incidence of death and MI. PCI was associated with a higher incidence of RRV but a lower incidence of stroke.
Source: Interactive CardioVascular and Thoracic Surgery - November 22, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Fanari, Z., Weiss, S. A., Zhang, W., Sonnad, S. S., Weintraub, W. S. Tags: Molecular biology Adult Cardiac Source Type: research

Coronary Stent Thrombosis With Vorapaxar Versus Placebo Results From the TRA 2°P-TIMI 50 Trial
BackgroundVorapaxar, a novel thrombin receptor antagonist, reduces cardiovascular death and recurrent thrombotic events when added to standard antiplatelet therapy in patients with stable atherosclerotic vascular disease.ObjectivesThe goal of this study was to test the hypothesis that treatment with vorapaxar reduces the rate of coronary stent thrombosis (ST) in stable patients with a history of coronary stenting.MethodsTRA 2°P-TIMI 50 (Trial to Assess the Effects of Vorapaxar in Preventing Heart Attack and Stroke in Patients With Atherosclerosis-Thrombolysis In Myocardial Infarction 50) was a multinational, randomized, d...
Source: Journal of the American College of Cardiology - December 1, 2014 Category: Cardiology Source Type: research

Long-term ischaemic and bleeding outcomes after primary percutaneous coronary intervention for ST-elevation myocardial infarction in the elderly.
CONCLUSION: Patients ≥ 80 years experienced high rates of ischaemic and bleeding complications; especially in this high-risk patient group individualised therapy is needed to optimise clinical outcomes. PMID: 26259967 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - August 11, 2015 Category: Cardiology Authors: Claessen BE, Kikkert WJ, Hoebers LP, Bahadurzada H, Vis MM, Baan J, Koch KT, de Winter RJ, Tijssen JG, Piek JJ, Henriques JP Tags: Neth Heart J Source Type: research

Long-term results of stenting versus coronary artery bypass surgery for left main coronary artery disease—A single-center experience
Conclusion PCI was a comparable alternative to CABG for high-risk patients with unprotected LM disease in terms of long-term risks of all-cause death/MI/stroke, but with a significantly higher repeat revascularization rate.
Source: Journal of the Chinese Medical Association - February 28, 2016 Category: Journals (General) Source Type: research

Pre-treatment clinical assessment in head and neck cancer: United Kingdom National Multidisciplinary Guidelines.
Authors: Robson A, Sturman J, Williamson P, Conboy P, Penney S, Wood H Abstract This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. This paper provides recommendations on the pre-treatment clinical assessment of patients presenting with head and neck cancer. Recommendations • Comorbidity data should be collected as it is important in the analysis of survival, quality of life and functional outcomes after treatment as well as for comparing results of different treatment regimens and different centres. (R) • Patients with hypertens...
Source: Journal of Laryngology and Otology - November 15, 2016 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research

Generalizability of EXCEL and NOBLE results to a large registry population with unprotected left main coronary artery disease
Conclusion: In the comparison of a large-sized, all-comer registry, the EXCEL trial might represent better generalizability with respect to baseline characteristics and observed clinical outcomes compared with the NOBLE trial.
Source: Coronary Artery Disease - November 2, 2017 Category: Cardiology Tags: Original Research Source Type: research

Outcomes of Coronary Artery Bypass Graft Surgery Versus Percutaneous Coronary Intervention in Patients Aged 18-45 Years with Diabetes Mellitus.
CONCLUSIONS: In DM patients aged 18-45 years, the cumulative survival rate, and freedom from MI and repeat revascularization for CABG were superior to those of PCI. However, a better trend to avoid stroke was observed with PCI. PMID: 29237922 [PubMed - in process]
Source: Chinese Medical Journal - December 15, 2017 Category: General Medicine Authors: Li Y, Dong R, Hua K, Liu TS, Zhou SY, Zhou N, Zhang HJ Tags: Chin Med J (Engl) Source Type: research

Stent versus Coronary Artery Bypass Surgery in Multi-Vessel and Left Main Coronary Artery Disease: A Meta-Analysis of Randomized Trials with Subgroups Evaluation
Conclusion: Compared with CABG, PCI using Stents showed lower 30 days mortality, higher late mortality and lower incidence of stroke. Diabetes and a high SYNTAX were the subgroups that influenced more adversely the results of PCI.Resumo Fundamento: A compara ção entre a intervenção coronária percutânea (ICP) utilizando stents e cirurgia de revascularização do miocárdio (CRM) permanece controversa. Objetivo: Realizar uma revisão sistemática com metanálise da ICP utilizando stents vs. CRM em estudos clínicos randomizados. Métodos: Foram pe squisadas bases de dados eletrônicas para identificar estudos randomiza...
Source: Arquivos Brasileiros de Cardiologia - June 7, 2019 Category: Cardiology Source Type: research

Evidence based decision making between PCI and CABG
Conclusion: Compared with CABG, PCI using Stents showed lower 30 days mortality, higher late mortality and lower incidence of stroke. Diabetes and a high SYNTAX were the subgroups that influenced more adversely the results of PCI.Resumo Fundamento: A compara ção entre a intervenção coronária percutânea (ICP) utilizando stents e cirurgia de revascularização do miocárdio (CRM) permanece controversa. Objetivo: Realizar uma revisão sistemática com metanálise da ICP utilizando stents vs. CRM em estudos clínicos randomizados. Métodos: Foram pe squisadas bases de dados eletrônicas para identificar estudos randomiza...
Source: Arquivos Brasileiros de Cardiologia - June 7, 2019 Category: Cardiology Source Type: research