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Condition: Staphylococcus Aureus

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Total 124 results found since Jan 2013.

Microbiological Etiologies of Pneumonia Complicating Stroke Clinical Sciences
Conclusions—Although the analysis was limited by small and heterogeneous study populations, limiting determination of microbiological causality, this review suggests aerobic Gram-negative bacilli and Gram-positive cocci are frequently associated with pneumonia complicating stroke. This supports the need for appropriately designed studies to determine microbial cause and a consensus-based approach in antibiotic usage and further targeted antibiotic treatment trials for enhanced antibiotic stewardship.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Amit K. Kishore, Andy Vail, Adam R. Jeans, Angel Chamorro, Mario Di Napoli, Lalit Kalra, Peter Langhorne, Christine Roffe, Willeke Westendorp, Paul J. Nederkoorn, Javier Garau, Diederik van de Beek, Joan Montaner, Mark Woodhead, Andreas Meisel, Craig J. S Tags: Complications, Meta Analysis, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Prophylactic antibiotics after acute stroke for reducing pneumonia in patients with dysphagia (STROKE-INF): a prospective, cluster-randomised, open-label, masked endpoint, controlled clinical trial
This study assessed the effectiveness of antibiotic prophylaxis for reducing pneumonia in patients with dysphagia after acute stroke. Methods We did a prospective, multicentre, cluster-randomised, open-label controlled trial with masked endpoint assessment of patients older than 18 years with dysphagia after new stroke recruited from 48 stroke units in the UK, accredited and included in the UK National Stroke Audit. We excluded patients with contraindications to antibiotics, pre-existing dysphagia, or known infections, or who were not expected to survive beyond 14 days. We randomly assigned the units (1:1) by computer to ...
Source: The Lancet - September 5, 2015 Category: Journals (General) Source Type: research

Staphylococcus aureus infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology.
CONCLUSIONS: Septic embolic stroke caused brain abscesses, increased mortality and upregulated Orm1 and Cxcl2 gene expressions compared to non-infected embolic stroke. The dramatic Orm1 increase observed in the septic group is unprecedented and suggests a significant biological role of Orm1 during septic neuroinflammation. PMID: 30707086 [PubMed - as supplied by publisher]
Source: Neurological Research - February 4, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Pre-operative stroke and neurological disability do not independently affect short- and long-term mortality in infective endocarditis patients
Conclusions Pre-operative stroke and the severity of neurological disability do not independently affect short- and long-term mortality in patients with infective endocarditis. It appears that patients with pre-operative stroke present with a generally higher risk profile. This information may substantially affect decision-making.
Source: Clinical Research in Cardiology - April 26, 2016 Category: Cardiology Source Type: research

A Meta-Analysis of Early Versus Delayed Surgery for Valvular Infective Endocarditis Complicated by Embolic Ischemic Stroke
Conclusions: In patients with valvular IE complicated by ischemic stroke, early surgery is associated with an increased risk of operative mortality, with no observed benefit in 1-year survival.
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - May 1, 2016 Category: Cardiovascular & Thoracic Surgery Tags: Original Articles Source Type: research

Genome-wide Integration Study of Circulating miRNAs and Peripheral Whole-Blood mRNAs of Male Acute Ischemic Stroke Patients
This study provides an integrated view of interactions among circulating miRNAs and peripheral whole-blood mRNAs involved in the pathophysiological processes of male AIS.
Source: Neuroscience - April 18, 2018 Category: Neuroscience Source Type: research

Treatment with IgM-enriched intravenous immunoglobulins (IgM-IVIg) enhances clearance of stroke-associated bacterial lung infection
Immunology. 2022 Jul 26. doi: 10.1111/imm.13553. Online ahead of print.ABSTRACTPost-stroke infection is a common complication of stroke that is associated with poor outcome. We previously reported that stroke induces an ablation of multiple sub-populations of B cells and reduces levels of IgM antibody, which coincides with the development of spontaneous bacterial pneumonia. The loss of IgM after stroke could be an important determinant of infection susceptibility and highlights this pathway as a target for intervention. We treated mice with a replacement dose of IgM-enriched intravenous immunoglobulin (IgM-IVIg) prior to a...
Source: Immunology - July 26, 2022 Category: Allergy & Immunology Authors: Laura McCulloch Alison J Harris Alexandra Malbon Michael J D Daniels Mehwish Younas John R Grainger Stuart M Allan Craig J Smith Barry W McColl Source Type: research

Hochuekkito can Prevent the Colonization of Methicillin-Resistant Staphylococcus aureus in Upper Respiratory Tract of Acute Stroke Patients
Conclusion: Our results indicate that the administration of HET may contribute to the prevention of MRSA colonization and promote rehabilitation in stroke patients.
Source: Frontiers in Pharmacology - June 28, 2021 Category: Drugs & Pharmacology Source Type: research

Effect of oral hygiene interventions on opportunistic pathogens in patients after stroke
Conclusions: In our study cohort, there was no significant difference in the effectiveness of the 3 different oral hygiene interventions on the prevalence or viable counts of oral opportunistic pathogens.
Source: American Journal of Infection Control - July 23, 2012 Category: Infectious Diseases Authors: Otto L.T. Lam, Anne S. McMillan, Lakshman P. Samaranayake, Leonard S.W. Li, Colman McGrath Tags: Major Articles Source Type: research

Oral health interventions using chlorhexidine - effects on the prevalence of oral opportunistic pathogens in stroke survivors: a randomized clinical trial
Conclusion Oral hygiene intervention, using a powered tooth brush and 1% Chlorhexidine oral gel was effective in reducing the prevalence of oral opportunistic pathogens. (187 words)
Source: Journal of Evidence Based Dental Practice - August 17, 2017 Category: Dentistry Source Type: research

Oral Health Interventions Using Chlorhexidine —Effects on the Prevalence of Oral Opportunistic Pathogens in Stroke Survivors: A Randomized Clinical Trial
Conclusion Oral hygiene intervention using a powered tooth brush and 1% chlorhexidine oral gel was effective in reducing the prevalence of oral opportunistic pathogens.
Source: Journal of Evidence Based Dental Practice - September 14, 2017 Category: Dentistry Source Type: research

Oral Health Interventions Using Chlorhexidine—Effects on the Prevalence of Oral Opportunistic Pathogens in Stroke Survivors: A Randomized Clinical Trial
ConclusionOral hygiene intervention using a powered tooth brush and 1% chlorhexidine oral gel was effective in reducing the prevalence of oral opportunistic pathogens.
Source: Journal of Evidence Based Dental Practice - July 5, 2018 Category: Dentistry Source Type: research