Staphylococcus aureus infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology.

CONCLUSIONS: Septic embolic stroke caused brain abscesses, increased mortality and upregulated Orm1 and Cxcl2 gene expressions compared to non-infected embolic stroke. The dramatic Orm1 increase observed in the septic group is unprecedented and suggests a significant biological role of Orm1 during septic neuroinflammation. PMID: 30707086 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30707086?dopt=Abstract

Source: Neurological Research - February 4, 2019 Category: Neurology Tags: Neurol Res Source Type: research